am 251 has been researched along with Malignant Melanoma in 2 studies
AM 251: an analog of SR141716A; structure given in first source
AM-251 : A carbohydrazide obtained by formal condensation of the carboxy group of 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid with the amino group of 1-aminopiperidine. An antagonist at the CB1 cannabinoid receptor.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Human cutaneous melanoma is an aggressive and chemotherapy-resistant type of cancer." | 1.42 | AM251 induces apoptosis and G2/M cell cycle arrest in A375 human melanoma cells. ( Adinolfi, B; Breschi, MC; Carpi, S; Costa, B; Da Pozzo, E; Fogli, S; Martini, C; Nieri, P; Pellegrino, M; Podestà, A; Romanini, A, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Carpi, S | 1 |
| Fogli, S | 1 |
| Romanini, A | 1 |
| Pellegrino, M | 1 |
| Adinolfi, B | 1 |
| Podestà, A | 1 |
| Costa, B | 1 |
| Da Pozzo, E | 1 |
| Martini, C | 1 |
| Breschi, MC | 1 |
| Nieri, P | 1 |
| Kenessey, I | 1 |
| Bánki, B | 1 |
| Márk, A | 1 |
| Varga, N | 1 |
| Tóvári, J | 1 |
| Ladányi, A | 1 |
| Rásó, E | 1 |
| Tímár, J | 1 |
2 other studies available for am 251 and Malignant Melanoma
| Article | Year |
|---|---|
AM251 induces apoptosis and G2/M cell cycle arrest in A375 human melanoma cells.
Topics: Antineoplastic Agents; Apoptosis; Calcium Channels; Celecoxib; Cell Line, Tumor; Cell Survival; Cycl | 2015 |
Revisiting CB1 receptor as drug target in human melanoma.
Topics: Animals; Apoptosis; Arachidonic Acids; Base Sequence; Cannabinoids; Cell Line, Tumor; Cell Movement; | 2012 |