am 251 has been researched along with Lesion of Sciatic Nerve in 2 studies
AM 251: an analog of SR141716A; structure given in first source
AM-251 : A carbohydrazide obtained by formal condensation of the carboxy group of 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid with the amino group of 1-aminopiperidine. An antagonist at the CB1 cannabinoid receptor.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mechanical allodynia and thermal hyperalgesia were evaluated in 46 rats allocated to receive: (1) Vehicle (before surgery)-Vehicle (after surgery); (2) Vehicle-WIN55,212-2; (3) WIN55,212-2-Vehicle; (4) WIN55,212-2-WIN55,212-2; (5) AM251+vehicle; (6) AM251+WIN55,212-2; (7) AM630+vehicle; (8) AM630+WIN55,212-2; (9) Sham receiving vehicle; and (10) Sham receiving WIN55,212-2." | 1.34 | Pre-emptive antinociceptive effects of a synthetic cannabinoid in a model of neuropathic pain. ( Beaulieu, P; Dani, M; Desroches, J; Guindon, J, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Guindon, J | 1 |
| Desroches, J | 1 |
| Dani, M | 1 |
| Beaulieu, P | 1 |
| Mitchell, VA | 1 |
| Greenwood, R | 1 |
| Jayamanne, A | 1 |
| Vaughan, CW | 1 |
2 other studies available for am 251 and Lesion of Sciatic Nerve
| Article | Year |
|---|---|
Pre-emptive antinociceptive effects of a synthetic cannabinoid in a model of neuropathic pain.
Topics: Analgesics; Animals; Benzoxazines; Cannabinoids; Hyperalgesia; Indoles; Male; Morpholines; Naphthale | 2007 |
Actions of the endocannabinoid transport inhibitor AM404 in neuropathic and inflammatory pain models.
Topics: Analgesics; Animals; Arachidonic Acids; Cannabinoid Receptor Modulators; Carrier Proteins; Disease M | 2007 |