Page last updated: 2024-10-22
am 251 and Leanness
am 251 has been researched along with Leanness in 2 studies
AM 251: an analog of SR141716A; structure given in first source
AM-251 : A carbohydrazide obtained by formal condensation of the carboxy group of 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid with the amino group of 1-aminopiperidine. An antagonist at the CB1 cannabinoid receptor.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "05); the dose-response curve was shifted to the left in the obese." | 1.34 | Effects of cannabinoid receptors on skeletal muscle oxidative pathways. ( Cameron-Smith, D; Cavuoto, P; Hatzinikolas, G; McAinch, AJ; Wittert, GA, 2007) |
Research
Studies (2)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Zhou, D | 1 |
| Shearman, LP | 1 |
| Cavuoto, P | 1 |
| McAinch, AJ | 1 |
| Hatzinikolas, G | 1 |
| Cameron-Smith, D | 1 |
| Wittert, GA | 1 |
Clinical Trials (1)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effects of Topical Cannabidiol Cream on Post-exercise Recovery[NCT05044936] | Early Phase 1 | 0 participants (Actual) | Interventional | 2023-05-15 | Withdrawn (stopped due to The researchers were not able to acquire funding to initiate the study. Also, the study was not approved by the local IRB which requested a FDA new drug application.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Trials
1 trial available for am 251 and Leanness
| Article | Year |
|---|---|
Voluntary exercise augments acute effects of CB1-receptor inverse agonist on body weight loss in obese and lean mice.
Topics: Animals; Body Weight; Dose-Response Relationship, Drug; Eating; Female; Mice; Mice, Inbred C57BL; Mi | 2004 |
Other Studies
1 other study available for am 251 and Leanness
| Article | Year |
|---|---|
Effects of cannabinoid receptors on skeletal muscle oxidative pathways.
Topics: Adult; AMP-Activated Protein Kinases; Arachidonic Acids; Cells, Cultured; Dose-Response Relationship | 2007 |