am 251 has been researched along with Injury, Ischemia-Reperfusion in 4 studies
AM 251: an analog of SR141716A; structure given in first source
AM-251 : A carbohydrazide obtained by formal condensation of the carboxy group of 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid with the amino group of 1-aminopiperidine. An antagonist at the CB1 cannabinoid receptor.
Excerpt | Relevance | Reference |
---|---|---|
"Mean intraocular pressure was increased up to 88." | 1.39 | Neuroprotective effects of topical CB1 agonist WIN 55212-2 on retinal ganglion cells after acute rise in intraocular pressure induced ischemia in rat. ( Pinar-Sueiro, S; Sharma, SC; Vecino, E; Veiga-Crespo, P; Zorrilla Hurtado, JÁ, 2013) |
"At 24h after the end of the last EA pretreatment, focal cerebral ischemia was induced by middle cerebral artery occlusion for 120min in rats." | 1.36 | Involvement of ERK 1/2 activation in electroacupuncture pretreatment via cannabinoid CB1 receptor in rats. ( Chen, S; Du, J; Hu, B; Lu, Y; Ma, L; Peng, Z; Wang, Q; Xiong, L; Zhao, Y; Zhu, X, 2010) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (25.00) | 29.6817 |
2010's | 3 (75.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Jing, N | 1 |
Fang, B | 1 |
Wang, ZL | 1 |
Ma, H | 1 |
Pinar-Sueiro, S | 1 |
Zorrilla Hurtado, JÁ | 1 |
Veiga-Crespo, P | 1 |
Sharma, SC | 1 |
Vecino, E | 1 |
Su, B | 1 |
Dong, H | 1 |
Ma, R | 1 |
Zhang, X | 1 |
Ding, Q | 1 |
Xiong, L | 2 |
Du, J | 1 |
Wang, Q | 1 |
Hu, B | 1 |
Peng, Z | 1 |
Zhao, Y | 1 |
Ma, L | 1 |
Lu, Y | 1 |
Zhu, X | 1 |
Chen, S | 1 |
4 other studies available for am 251 and Injury, Ischemia-Reperfusion
Article | Year |
---|---|
Remote Ischemia Preconditioning Attenuates Blood-Spinal Cord Barrier Breakdown in Rats Undergoing Spinal Cord Ischemia Reperfusion Injury: Associated with Activation and Upregulation of CB1 and CB2 Receptors.
Topics: Animals; Disease Models, Animal; Down-Regulation; Femoral Artery; Indoles; Ischemic Preconditioning; | 2017 |
Neuroprotective effects of topical CB1 agonist WIN 55212-2 on retinal ganglion cells after acute rise in intraocular pressure induced ischemia in rat.
Topics: Administration, Topical; Animals; Benzoxazines; Cell Count; Disease Models, Animal; Female; Intraocu | 2013 |
Cannabinoid 1 receptor mediation of spinal cord ischemic tolerance induced by limb remote ischemia preconditioning in rats.
Topics: Animals; Cannabinoid Receptor Antagonists; Cannabinoid Receptor Modulators; Indoles; Ischemia; Ische | 2009 |
Involvement of ERK 1/2 activation in electroacupuncture pretreatment via cannabinoid CB1 receptor in rats.
Topics: Animals; Behavior, Animal; Blotting, Western; Brain Ischemia; Butadienes; Electroacupuncture; Enzyme | 2010 |