Page last updated: 2024-10-22

am 251 and Injury, Ischemia-Reperfusion

am 251 has been researched along with Injury, Ischemia-Reperfusion in 4 studies

AM 251: an analog of SR141716A; structure given in first source
AM-251 : A carbohydrazide obtained by formal condensation of the carboxy group of 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid with the amino group of 1-aminopiperidine. An antagonist at the CB1 cannabinoid receptor.

Research Excerpts

ExcerptRelevanceReference
"Mean intraocular pressure was increased up to 88."1.39Neuroprotective effects of topical CB1 agonist WIN 55212-2 on retinal ganglion cells after acute rise in intraocular pressure induced ischemia in rat. ( Pinar-Sueiro, S; Sharma, SC; Vecino, E; Veiga-Crespo, P; Zorrilla Hurtado, JÁ, 2013)
"At 24h after the end of the last EA pretreatment, focal cerebral ischemia was induced by middle cerebral artery occlusion for 120min in rats."1.36Involvement of ERK 1/2 activation in electroacupuncture pretreatment via cannabinoid CB1 receptor in rats. ( Chen, S; Du, J; Hu, B; Lu, Y; Ma, L; Peng, Z; Wang, Q; Xiong, L; Zhao, Y; Zhu, X, 2010)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jing, N1
Fang, B1
Wang, ZL1
Ma, H1
Pinar-Sueiro, S1
Zorrilla Hurtado, JÁ1
Veiga-Crespo, P1
Sharma, SC1
Vecino, E1
Su, B1
Dong, H1
Ma, R1
Zhang, X1
Ding, Q1
Xiong, L2
Du, J1
Wang, Q1
Hu, B1
Peng, Z1
Zhao, Y1
Ma, L1
Lu, Y1
Zhu, X1
Chen, S1

Other Studies

4 other studies available for am 251 and Injury, Ischemia-Reperfusion

ArticleYear
Remote Ischemia Preconditioning Attenuates Blood-Spinal Cord Barrier Breakdown in Rats Undergoing Spinal Cord Ischemia Reperfusion Injury: Associated with Activation and Upregulation of CB1 and CB2 Receptors.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2017, Volume: 43, Issue:6

    Topics: Animals; Disease Models, Animal; Down-Regulation; Femoral Artery; Indoles; Ischemic Preconditioning;

2017
Neuroprotective effects of topical CB1 agonist WIN 55212-2 on retinal ganglion cells after acute rise in intraocular pressure induced ischemia in rat.
    Experimental eye research, 2013, Volume: 110

    Topics: Administration, Topical; Animals; Benzoxazines; Cell Count; Disease Models, Animal; Female; Intraocu

2013
Cannabinoid 1 receptor mediation of spinal cord ischemic tolerance induced by limb remote ischemia preconditioning in rats.
    The Journal of thoracic and cardiovascular surgery, 2009, Volume: 138, Issue:6

    Topics: Animals; Cannabinoid Receptor Antagonists; Cannabinoid Receptor Modulators; Indoles; Ischemia; Ische

2009
Involvement of ERK 1/2 activation in electroacupuncture pretreatment via cannabinoid CB1 receptor in rats.
    Brain research, 2010, Nov-11, Volume: 1360

    Topics: Animals; Behavior, Animal; Blotting, Western; Brain Ischemia; Butadienes; Electroacupuncture; Enzyme

2010