am 251 has been researched along with Infarction, Middle Cerebral Artery in 3 studies
AM 251: an analog of SR141716A; structure given in first source
AM-251 : A carbohydrazide obtained by formal condensation of the carboxy group of 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid with the amino group of 1-aminopiperidine. An antagonist at the CB1 cannabinoid receptor.
Infarction, Middle Cerebral Artery: NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "At 24h after the end of the last EA pretreatment, focal cerebral ischemia was induced by middle cerebral artery occlusion for 120min in rats." | 1.36 | Involvement of ERK 1/2 activation in electroacupuncture pretreatment via cannabinoid CB1 receptor in rats. ( Chen, S; Du, J; Hu, B; Lu, Y; Ma, L; Peng, Z; Wang, Q; Xiong, L; Zhao, Y; Zhu, X, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Du, J | 1 |
| Wang, Q | 1 |
| Hu, B | 1 |
| Peng, Z | 1 |
| Zhao, Y | 1 |
| Ma, L | 1 |
| Xiong, L | 1 |
| Lu, Y | 1 |
| Zhu, X | 1 |
| Chen, S | 1 |
| Rojo, ML | 1 |
| Söderström, I | 1 |
| Fowler, CJ | 1 |
| Suzuki, N | 1 |
| Suzuki, M | 1 |
| Hamajo, K | 1 |
| Murakami, K | 1 |
| Tsukamoto, T | 1 |
| Shimojo, M | 1 |
3 other studies available for am 251 and Infarction, Middle Cerebral Artery
| Article | Year |
|---|---|
Involvement of ERK 1/2 activation in electroacupuncture pretreatment via cannabinoid CB1 receptor in rats.
Topics: Animals; Behavior, Animal; Blotting, Western; Brain Ischemia; Butadienes; Electroacupuncture; Enzyme | 2010 |
Residual effects of focal brain ischaemia upon cannabinoid CB(1) receptor density and functionality in female rats.
Topics: Animals; Autoradiography; Brain; Brain Ischemia; Cyclohexanols; Disease Models, Animal; Estradiol; E | 2011 |
Contribution of hypothermia and CB1 receptor activation to protective effects of TAK-937, a cannabinoid receptor agonist, in rat transient MCAO model.
Topics: Amides; Animals; Benzofurans; Body Temperature; Disease Models, Animal; Hypothermia; Infarction, Mid | 2012 |