Page last updated: 2024-10-22

am 251 and Hyperesthesia

am 251 has been researched along with Hyperesthesia in 2 studies

AM 251: an analog of SR141716A; structure given in first source
AM-251 : A carbohydrazide obtained by formal condensation of the carboxy group of 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid with the amino group of 1-aminopiperidine. An antagonist at the CB1 cannabinoid receptor.

Hyperesthesia: Increased sensitivity to cutaneous stimulation due to a diminished threshold or an increased response to stimuli.

Research Excerpts

ExcerptRelevanceReference
"Both mechanical allodynia and thermal hyperalgesia are seen both ipsilateral and contralateral to the side of nerve injury, but is significantly more severe ipsilaterally."1.34The synthetic cannabinoids attenuate allodynia and hyperalgesia in a rat model of trigeminal neuropathic pain. ( Hsu, KS; Huang, CC; Liang, YC, 2007)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hama, A1
Sagen, J1
Liang, YC1
Huang, CC1
Hsu, KS1

Other Studies

2 other studies available for am 251 and Hyperesthesia

ArticleYear
Antinociceptive effect of cannabinoid agonist WIN 55,212-2 in rats with a spinal cord injury.
    Experimental neurology, 2007, Volume: 204, Issue:1

    Topics: Analgesics; Animals; Benzoxazines; Cannabinoid Receptor Agonists; Hindlimb; Hyperesthesia; Male; Mor

2007
The synthetic cannabinoids attenuate allodynia and hyperalgesia in a rat model of trigeminal neuropathic pain.
    Neuropharmacology, 2007, Volume: 53, Issue:1

    Topics: Analgesics; Analysis of Variance; Animals; Benzoxazines; Cannabinoids; Disease Models, Animal; Dose-

2007