am 251 has been researched along with Hyperesthesia in 2 studies
AM 251: an analog of SR141716A; structure given in first source
AM-251 : A carbohydrazide obtained by formal condensation of the carboxy group of 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid with the amino group of 1-aminopiperidine. An antagonist at the CB1 cannabinoid receptor.
Hyperesthesia: Increased sensitivity to cutaneous stimulation due to a diminished threshold or an increased response to stimuli.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Both mechanical allodynia and thermal hyperalgesia are seen both ipsilateral and contralateral to the side of nerve injury, but is significantly more severe ipsilaterally." | 1.34 | The synthetic cannabinoids attenuate allodynia and hyperalgesia in a rat model of trigeminal neuropathic pain. ( Hsu, KS; Huang, CC; Liang, YC, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hama, A | 1 |
| Sagen, J | 1 |
| Liang, YC | 1 |
| Huang, CC | 1 |
| Hsu, KS | 1 |
2 other studies available for am 251 and Hyperesthesia
| Article | Year |
|---|---|
Antinociceptive effect of cannabinoid agonist WIN 55,212-2 in rats with a spinal cord injury.
Topics: Analgesics; Animals; Benzoxazines; Cannabinoid Receptor Agonists; Hindlimb; Hyperesthesia; Male; Mor | 2007 |
The synthetic cannabinoids attenuate allodynia and hyperalgesia in a rat model of trigeminal neuropathic pain.
Topics: Analgesics; Analysis of Variance; Animals; Benzoxazines; Cannabinoids; Disease Models, Animal; Dose- | 2007 |