am 251 has been researched along with Gastric Ulcer in 3 studies
AM 251: an analog of SR141716A; structure given in first source
AM-251 : A carbohydrazide obtained by formal condensation of the carboxy group of 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid with the amino group of 1-aminopiperidine. An antagonist at the CB1 cannabinoid receptor.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the present study, we tested the effects (in rats) of a simple extract of medicinal cannabis (called "MFF") for its ability to promote resolution of colitis, to prevent gastric damage induced by naproxen, and to reduce gastric distention-induced visceral pain." | 3.79 | Pro-resolution, protective and anti-nociceptive effects of a cannabis extract in the rat gastrointestinal tract. ( Ferraz, JG; Flannigan, KL; McKnight, W; Tuitt, D; Wallace, JL; Wang, L, 2013) |
| "Treatment with AM 251 aggravated gastric damage and reversed protective effect of anandamide administration." | 1.33 | Cannabinoids in acute gastric damage and pancreatitis. ( Ceranowicz, P; Cieszkowski, J; Dembiński, A; Dembiński, M; Hładki, W; Konturek, PC; Konturek, SJ; Pawlik, WW; Tomaszewska, R; Warzecha, Z, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wallace, JL | 1 |
| Flannigan, KL | 1 |
| McKnight, W | 1 |
| Wang, L | 1 |
| Ferraz, JG | 1 |
| Tuitt, D | 1 |
| Gyires, K | 1 |
| Rónai, AZ | 1 |
| Zádori, ZS | 1 |
| Tóth, VE | 1 |
| Németh, J | 1 |
| Szekeres, M | 1 |
| Hunyady, L | 1 |
| Dembiński, A | 1 |
| Warzecha, Z | 1 |
| Ceranowicz, P | 1 |
| Dembiński, M | 1 |
| Cieszkowski, J | 1 |
| Pawlik, WW | 1 |
| Konturek, SJ | 1 |
| Tomaszewska, R | 1 |
| Hładki, W | 1 |
| Konturek, PC | 1 |
3 other studies available for am 251 and Gastric Ulcer
| Article | Year |
|---|---|
Pro-resolution, protective and anti-nociceptive effects of a cannabis extract in the rat gastrointestinal tract.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cannabis; Colitis; Gastrointestinal Tr | 2013 |
Angiotensin II-induced activation of central AT1 receptors exerts endocannabinoid-mediated gastroprotective effect in rats.
Topics: Angiotensin II; Animals; Atropine; CHO Cells; Cricetulus; Ethanol; Gastric Mucosa; Gene Expression R | 2014 |
Cannabinoids in acute gastric damage and pancreatitis.
Topics: Acute Disease; Animals; Arachidonic Acids; Cannabinoids; Ceruletide; DNA; Endocannabinoids; Gastric | 2006 |