am 251 has been researched along with Fatty Liver in 1 studies
AM 251: an analog of SR141716A; structure given in first source
AM-251 : A carbohydrazide obtained by formal condensation of the carboxy group of 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid with the amino group of 1-aminopiperidine. An antagonist at the CB1 cannabinoid receptor.
Fatty Liver: Lipid infiltration of the hepatic parenchymal cells resulting in a yellow-colored liver. The abnormal lipid accumulation is usually in the form of TRIGLYCERIDES, either as a single large droplet or multiple small droplets. Fatty liver is caused by an imbalance in the metabolism of FATTY ACIDS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our results indicate that the cannabinoid CB1 inverse agonist AM 251 represents a promising therapeutic strategy for the treatment of obesity and metabolic syndrome." | 7.79 | Novel effects of the cannabinoid inverse agonist AM 251 on parameters related to metabolic syndrome in obese Zucker rats. ( Aranda, P; Errami, M; Galisteo, M; Llopis, J; López-Chaves, C; López-Jurado, M; Martínez, R; Merroun, I; Porres, JM; Sánchez-González, C; Zarzuelo, A, 2013) |
| "Our results indicate that the cannabinoid CB1 inverse agonist AM 251 represents a promising therapeutic strategy for the treatment of obesity and metabolic syndrome." | 3.79 | Novel effects of the cannabinoid inverse agonist AM 251 on parameters related to metabolic syndrome in obese Zucker rats. ( Aranda, P; Errami, M; Galisteo, M; Llopis, J; López-Chaves, C; López-Jurado, M; Martínez, R; Merroun, I; Porres, JM; Sánchez-González, C; Zarzuelo, A, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Merroun, I | 1 |
| Sánchez-González, C | 1 |
| Martínez, R | 1 |
| López-Chaves, C | 1 |
| Porres, JM | 1 |
| Aranda, P | 1 |
| Llopis, J | 1 |
| Galisteo, M | 1 |
| Zarzuelo, A | 1 |
| Errami, M | 1 |
| López-Jurado, M | 1 |
1 other study available for am 251 and Fatty Liver
| Article | Year |
|---|---|
Novel effects of the cannabinoid inverse agonist AM 251 on parameters related to metabolic syndrome in obese Zucker rats.
Topics: Animals; Biomarkers; Cannabinoid Receptor Antagonists; Eating; Energy Metabolism; Fatty Liver; Insul | 2013 |