am 251 has been researched along with Cirrhosis, Liver in 2 studies
AM 251: an analog of SR141716A; structure given in first source
AM-251 : A carbohydrazide obtained by formal condensation of the carboxy group of 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid with the amino group of 1-aminopiperidine. An antagonist at the CB1 cannabinoid receptor.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Advanced liver cirrhosis is associated with hyperdynamic circulation consisting of systemic hypotension, decreased peripheral resistance, and cardiac dysfunction, termed cirrhotic cardiomyopathy." | 1.34 | Endocannabinoids acting at CB1 receptors mediate the cardiac contractile dysfunction in vivo in cirrhotic rats. ( Bátkai, S; Harvey-White, J; Kechrid, R; Kunos, G; Mukhopadhyay, P; Pacher, P, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gaskari, SA | 1 |
| Liu, H | 1 |
| D'Mello, C | 1 |
| Kunos, G | 2 |
| Lee, SS | 1 |
| Bátkai, S | 1 |
| Mukhopadhyay, P | 1 |
| Harvey-White, J | 1 |
| Kechrid, R | 1 |
| Pacher, P | 1 |
2 other studies available for am 251 and Cirrhosis, Liver
| Article | Year |
|---|---|
Blunted cardiac response to hemorrhage in cirrhotic rats is mediated by local macrophage-released endocannabinoids.
Topics: Animals; Arachidonic Acids; Blood Pressure; Cardiac Output; Endocannabinoids; Gadolinium; Glycerides | 2015 |
Endocannabinoids acting at CB1 receptors mediate the cardiac contractile dysfunction in vivo in cirrhotic rats.
Topics: Amidohydrolases; Animals; Blood Pressure; Cannabinoid Receptor Modulators; Carbon Tetrachloride; Dis | 2007 |