am 251 has been researched along with Cirrhoses, Experimental Liver in 2 studies
AM 251: an analog of SR141716A; structure given in first source
AM-251 : A carbohydrazide obtained by formal condensation of the carboxy group of 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid with the amino group of 1-aminopiperidine. An antagonist at the CB1 cannabinoid receptor.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Anandamide can activate potassium (K(+)) channels to induce an endothelium-dependent vasorelaxation in normal rat mesenteric arteries." | 5.34 | Role of Ca2+-dependent potassium channels in in vitro anandamide-mediated mesenteric vasorelaxation in rats with biliary cirrhosis. ( Hou, MC; Huang, YT; Lee, FY; Lee, SD; Lee, TY; Lin, HC; Wang, YW; Yang, YY, 2007) |
| "Anandamide can activate potassium (K(+)) channels to induce an endothelium-dependent vasorelaxation in normal rat mesenteric arteries." | 1.34 | Role of Ca2+-dependent potassium channels in in vitro anandamide-mediated mesenteric vasorelaxation in rats with biliary cirrhosis. ( Hou, MC; Huang, YT; Lee, FY; Lee, SD; Lee, TY; Lin, HC; Wang, YW; Yang, YY, 2007) |
| " Dose-response curve for a beta-adrenergic agonist isoproterenol was constructed in the presence and absence of a CB-1 antagonist AM251 (1 microM)." | 1.33 | Role of endocannabinoids in the pathogenesis of cirrhotic cardiomyopathy in bile duct-ligated rats. ( Baik, SK; Gaskari, SA; Lee, SS; Li, Y; Liu, H; Moezi, L, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gaskari, SA | 1 |
| Liu, H | 1 |
| Moezi, L | 1 |
| Li, Y | 1 |
| Baik, SK | 1 |
| Lee, SS | 1 |
| Yang, YY | 1 |
| Lin, HC | 1 |
| Huang, YT | 1 |
| Lee, TY | 1 |
| Hou, MC | 1 |
| Wang, YW | 1 |
| Lee, FY | 1 |
| Lee, SD | 1 |
2 other studies available for am 251 and Cirrhoses, Experimental Liver
| Article | Year |
|---|---|
Role of endocannabinoids in the pathogenesis of cirrhotic cardiomyopathy in bile duct-ligated rats.
Topics: Amidohydrolases; Animals; Arachidonic Acids; Bile Ducts; Cardiomyopathies; Endocannabinoids; Gene Ex | 2005 |
Role of Ca2+-dependent potassium channels in in vitro anandamide-mediated mesenteric vasorelaxation in rats with biliary cirrhosis.
Topics: Acetylcholine; Animals; Apamin; Arachidonic Acids; Cannabinoid Receptor Modulators; Charybdotoxin; C | 2007 |