am 251 and Chronic Infantile Neurologic, Cutaneous, and Articular Syndrome studies

AM 251: an analog of SR141716A; structure given in first source
AM-251 : A carbohydrazide obtained by formal condensation of the carboxy group of 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid with the amino group of 1-aminopiperidine. An antagonist at the CB1 cannabinoid receptor.

Research Excerpts

Excerpt	Relevance	Reference
") suppressed the maintenance of mechanical and cold allodynia in the cisplatin and paclitaxel models."	7.78	The maintenance of cisplatin- and paclitaxel-induced mechanical and cold allodynia is suppressed by cannabinoid CB₂ receptor activation and independent of CXCR4 signaling in models of chemotherapy-induced peripheral neuropathy. ( Deng, L; Guindon, J; Hohmann, AG; Makriyannis, A; Thakur, GA; Vemuri, VK; White, FA, 2012)
") suppressed the maintenance of mechanical and cold allodynia in the cisplatin and paclitaxel models."	3.78	The maintenance of cisplatin- and paclitaxel-induced mechanical and cold allodynia is suppressed by cannabinoid CB₂ receptor activation and independent of CXCR4 signaling in models of chemotherapy-induced peripheral neuropathy. ( Deng, L; Guindon, J; Hohmann, AG; Makriyannis, A; Thakur, GA; Vemuri, VK; White, FA, 2012)

Research

Studies (1)

Authors

Other Studies

1 other study available for am 251 and Chronic Infantile Neurologic, Cutaneous, and Articular Syndrome

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors	Studies
Deng, L	1
Guindon, J	1
Vemuri, VK	1
Thakur, GA	1
White, FA	1
Makriyannis, A	1
Hohmann, AG	1