Page last updated: 2024-10-22

am 251 and Burns

am 251 has been researched along with Burns in 2 studies

AM 251: an analog of SR141716A; structure given in first source
AM-251 : A carbohydrazide obtained by formal condensation of the carboxy group of 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid with the amino group of 1-aminopiperidine. An antagonist at the CB1 cannabinoid receptor.

Burns: Injuries to tissues caused by contact with heat, steam, chemicals (BURNS, CHEMICAL), electricity (BURNS, ELECTRIC), or the like.

Research Excerpts

ExcerptRelevanceReference
"Mechanical allodynia and thermal hyperalgesia were tested on ventral paw for 14 days."1.40Cannabinoid receptor type 1 antagonist, AM251, attenuates mechanical allodynia and thermal hyperalgesia after burn injury. ( Iwasaki, H; Mao, J; Martyn, JA; Murata, E; Poon, KY; Ueda, M; Wang, S, 2014)
"WIN 55,212-2 attenuated both heat and mechanical hyperalgesia dose-dependently."1.32Activation of peripheral cannabinoid receptors attenuates cutaneous hyperalgesia produced by a heat injury. ( Johanek, LM; Simone, DA, 2004)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ueda, M1
Iwasaki, H1
Wang, S1
Murata, E1
Poon, KY1
Mao, J1
Martyn, JA1
Johanek, LM1
Simone, DA1

Other Studies

2 other studies available for am 251 and Burns

ArticleYear
Cannabinoid receptor type 1 antagonist, AM251, attenuates mechanical allodynia and thermal hyperalgesia after burn injury.
    Anesthesiology, 2014, Volume: 121, Issue:6

    Topics: Aging; Analgesics, Non-Narcotic; Animals; Burns; Hyperalgesia; Injections, Spinal; Male; Neuroglia;

2014
Activation of peripheral cannabinoid receptors attenuates cutaneous hyperalgesia produced by a heat injury.
    Pain, 2004, Volume: 109, Issue:3

    Topics: Animals; Benzoxazines; Burns; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Disea

2004