am 251 has been researched along with Burns in 2 studies
AM 251: an analog of SR141716A; structure given in first source
AM-251 : A carbohydrazide obtained by formal condensation of the carboxy group of 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid with the amino group of 1-aminopiperidine. An antagonist at the CB1 cannabinoid receptor.
Burns: Injuries to tissues caused by contact with heat, steam, chemicals (BURNS, CHEMICAL), electricity (BURNS, ELECTRIC), or the like.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mechanical allodynia and thermal hyperalgesia were tested on ventral paw for 14 days." | 1.40 | Cannabinoid receptor type 1 antagonist, AM251, attenuates mechanical allodynia and thermal hyperalgesia after burn injury. ( Iwasaki, H; Mao, J; Martyn, JA; Murata, E; Poon, KY; Ueda, M; Wang, S, 2014) |
| "WIN 55,212-2 attenuated both heat and mechanical hyperalgesia dose-dependently." | 1.32 | Activation of peripheral cannabinoid receptors attenuates cutaneous hyperalgesia produced by a heat injury. ( Johanek, LM; Simone, DA, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ueda, M | 1 |
| Iwasaki, H | 1 |
| Wang, S | 1 |
| Murata, E | 1 |
| Poon, KY | 1 |
| Mao, J | 1 |
| Martyn, JA | 1 |
| Johanek, LM | 1 |
| Simone, DA | 1 |
2 other studies available for am 251 and Burns
| Article | Year |
|---|---|
Cannabinoid receptor type 1 antagonist, AM251, attenuates mechanical allodynia and thermal hyperalgesia after burn injury.
Topics: Aging; Analgesics, Non-Narcotic; Animals; Burns; Hyperalgesia; Injections, Spinal; Male; Neuroglia; | 2014 |
Activation of peripheral cannabinoid receptors attenuates cutaneous hyperalgesia produced by a heat injury.
Topics: Animals; Benzoxazines; Burns; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Disea | 2004 |