Page last updated: 2024-10-22

am 251 and Brain Swelling

am 251 has been researched along with Brain Swelling in 2 studies

AM 251: an analog of SR141716A; structure given in first source
AM-251 : A carbohydrazide obtained by formal condensation of the carboxy group of 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid with the amino group of 1-aminopiperidine. An antagonist at the CB1 cannabinoid receptor.

Research Excerpts

ExcerptRelevanceReference
"The results showed that JZL lowered brain infarction, neurological disorders, TNF-α and MMP9 more effectively than JZL plus AM251."1.48JZL184, as a monoacylglycerol lipase inhibitor, down-regulates inflammation in a cannabinoid pathway dependent manner. ( Allahtavakoli, M; Bazmandegan, G; Moghadam-Ahmadi, A; Rahmani, MR; Shamsizadeh, A, 2018)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rahmani, MR1
Shamsizadeh, A1
Moghadam-Ahmadi, A1
Bazmandegan, G1
Allahtavakoli, M1
Lopez-Rodriguez, AB1
Siopi, E1
Finn, DP1
Marchand-Leroux, C1
Garcia-Segura, LM1
Jafarian-Tehrani, M1
Viveros, MP1

Other Studies

2 other studies available for am 251 and Brain Swelling

ArticleYear
JZL184, as a monoacylglycerol lipase inhibitor, down-regulates inflammation in a cannabinoid pathway dependent manner.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 103

    Topics: Animals; Benzodioxoles; Brain Edema; Brain Infarction; Cannabinoids; Down-Regulation; Enzyme Inhibit

2018
CB1 and CB2 cannabinoid receptor antagonists prevent minocycline-induced neuroprotection following traumatic brain injury in mice.
    Cerebral cortex (New York, N.Y. : 1991), 2015, Volume: 25, Issue:1

    Topics: Animals; Axons; Brain; Brain Edema; Brain Injuries; Cannabinoid Receptor Antagonists; Indoles; Male;

2015