am 251 has been researched along with Bone Loss, Osteoclastic in 3 studies
AM 251: an analog of SR141716A; structure given in first source
AM-251 : A carbohydrazide obtained by formal condensation of the carboxy group of 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid with the amino group of 1-aminopiperidine. An antagonist at the CB1 cannabinoid receptor.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Accelerated osteoclastic bone resorption has a central role in the pathogenesis of osteoporosis and other bone diseases." | 1.33 | Regulation of bone mass, bone loss and osteoclast activity by cannabinoid receptors. ( Baker, D; Greig, IR; Idris, AI; Ralston, SH; Ridge, SA; Ross, RA; van 't Hof, RJ, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Allen, JG | 1 |
| Fotsch, C | 1 |
| Babij, P | 1 |
| Idris, AI | 2 |
| Sophocleous, A | 1 |
| Landao-Bassonga, E | 1 |
| van't Hof, RJ | 1 |
| Ralston, SH | 2 |
| van 't Hof, RJ | 1 |
| Greig, IR | 1 |
| Ridge, SA | 1 |
| Baker, D | 1 |
| Ross, RA | 1 |
1 review available for am 251 and Bone Loss, Osteoclastic
| Article | Year |
|---|---|
Emerging targets in osteoporosis disease modification.
Topics: Animals; Biomarkers; Bone Density; Bone Resorption; Humans; Osteoporosis | 2010 |
2 other studies available for am 251 and Bone Loss, Osteoclastic
| Article | Year |
|---|---|
Regulation of bone mass, osteoclast function, and ovariectomy-induced bone loss by the type 2 cannabinoid receptor.
Topics: Animals; Bone and Bones; Bone Density; Bone Marrow Cells; Bone Resorption; Cannabinoids; Cells, Cult | 2008 |
Regulation of bone mass, bone loss and osteoclast activity by cannabinoid receptors.
Topics: Animals; Apoptosis; Bone and Bones; Bone Density; Bone Resorption; Camphanes; Carrier Proteins; Cell | 2005 |