am 251 has been researched along with Blood Pressure, Low in 3 studies
AM 251: an analog of SR141716A; structure given in first source
AM-251 : A carbohydrazide obtained by formal condensation of the carboxy group of 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid with the amino group of 1-aminopiperidine. An antagonist at the CB1 cannabinoid receptor.
| Excerpt | Relevance | Reference |
|---|---|---|
| "When SR141716A or AM251 was administered, the MAP response to NE was (41." | 1.35 | CB1 cannabinoid receptor participates in the vascular hyporeactivity resulting from hemorrhagic shock in rats. ( Hou, LC; Ji, GL; Li, N; Lu, Y; Wang, YM; Xie, KL; Xiong, LZ; Zheng, LN, 2009) |
| "Anandamide was able to inhibit dural blood vessel dilation brought about by electrical stimulation by 50%, calcitonin gene-related peptide (CGRP) by 30%, capsaicin by 45%, and nitric oxide by 40%." | 1.32 | Anandamide is able to inhibit trigeminal neurons using an in vivo model of trigeminovascular-mediated nociception. ( Akerman, S; Goadsby, PJ; Kaube, H, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hou, LC | 1 |
| Li, N | 1 |
| Zheng, LN | 1 |
| Lu, Y | 1 |
| Xie, KL | 1 |
| Wang, YM | 1 |
| Ji, GL | 1 |
| Xiong, LZ | 1 |
| Akerman, S | 1 |
| Kaube, H | 1 |
| Goadsby, PJ | 1 |
| Bátkai, S | 1 |
| Pacher, P | 1 |
| Járai, Z | 1 |
| Wagner, JA | 1 |
| Kunos, G | 1 |
3 other studies available for am 251 and Blood Pressure, Low
| Article | Year |
|---|---|
CB1 cannabinoid receptor participates in the vascular hyporeactivity resulting from hemorrhagic shock in rats.
Topics: Animals; Blotting, Western; Gene Expression Regulation; Hypotension; Male; Piperidines; Pyrazoles; R | 2009 |
Anandamide is able to inhibit trigeminal neurons using an in vivo model of trigeminovascular-mediated nociception.
Topics: Animals; Arachidonic Acids; Blood Pressure; Calcitonin Gene-Related Peptide; Capsaicin; Electric Sti | 2004 |
Cannabinoid antagonist SR-141716 inhibits endotoxic hypotension by a cardiac mechanism not involving CB1 or CB2 receptors.
Topics: Animals; Cannabinoids; Endotoxins; Heart; Heart Rate; Hemodynamics; Hypotension; Male; Mice; Mice, K | 2004 |