am 251 has been researched along with Autosomal Dominant Juvenile Parkinson Disease in 2 studies
AM 251: an analog of SR141716A; structure given in first source
AM-251 : A carbohydrazide obtained by formal condensation of the carboxy group of 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid with the amino group of 1-aminopiperidine. An antagonist at the CB1 cannabinoid receptor.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The long-term use of levodopa as a pharmacotherapy for Parkinson's disease is limited by the development of levodopa-induced dyskinesias." | 1.36 | The effects of cannabinoid drugs on abnormal involuntary movements in dyskinetic and non-dyskinetic 6-hydroxydopamine lesioned rats. ( Dowd, E; Finn, DP; Gorman, AM; Walsh, S, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Walsh, S | 1 |
| Gorman, AM | 1 |
| Finn, DP | 1 |
| Dowd, E | 1 |
| Fernandez-Espejo, E | 1 |
| Caraballo, I | 1 |
| Rodriguez de Fonseca, F | 1 |
| Ferrer, B | 1 |
| El Banoua, F | 1 |
| Flores, JA | 1 |
| Galan-Rodriguez, B | 1 |
2 other studies available for am 251 and Autosomal Dominant Juvenile Parkinson Disease
| Article | Year |
|---|---|
The effects of cannabinoid drugs on abnormal involuntary movements in dyskinetic and non-dyskinetic 6-hydroxydopamine lesioned rats.
Topics: Animals; Antiparkinson Agents; Disease Models, Animal; Dronabinol; Dyskinesia, Drug-Induced; Levodop | 2010 |
Experimental parkinsonism alters anandamide precursor synthesis, and functional deficits are improved by AM404: a modulator of endocannabinoid function.
Topics: Acyltransferases; Amidohydrolases; Amphetamine; Analysis of Variance; Animals; Antiparkinson Agents; | 2004 |