am 251 and Anochlesia
am 251 has been researched along with Anochlesia in 5 studies
AM 251: an analog of SR141716A; structure given in first source
AM-251 : A carbohydrazide obtained by formal condensation of the carboxy group of 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid with the amino group of 1-aminopiperidine. An antagonist at the CB1 cannabinoid receptor.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " The general aims of this study were to: 1) examine whether the limited antagonist activity of SR 141716A generalizes to the cannabinoid CB(1) antagonist N-(piperidin-1-yl)-5-(4-iodophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (AM 251); and 2) examine mechanisms by which cannabinoids produce hypothermia, catalepsy, and hypoactivity in C57BL/6J mice." | 3.74 | Differences in the relative potency of SR 141716A and AM 251 as antagonists of various in vivo effects of cannabinoid agonists in C57BL/6J mice. ( Koek, W; McMahon, LR, 2007) |
| "Both the catalepsy and analgesia induced by different doses of the synthetic cannabinoid WIN 55,212-2 (2 and 4 mg/kg, i." | 1.35 | Modulation by female sex hormones of the cannabinoid-induced catalepsy and analgesia in ovariectomized mice. ( Dehpour, AR; Ejtemaei Mehr, S; Ghasemi, M; Javadi, P; Kalbasi Anaraki, D; Paydar, MJ; Sadeghi, M; Sianati, S, 2008) |
Research
Studies (5)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Vigolo, A | 1 |
| Ossato, A | 2 |
| Trapella, C | 2 |
| Vincenzi, F | 2 |
| Rimondo, C | 2 |
| Seri, C | 1 |
| Varani, K | 2 |
| Serpelloni, G | 2 |
| Marti, M | 2 |
| Canazza, I | 1 |
| Fantinati, A | 1 |
| De Luca, MA | 1 |
| Margiani, G | 1 |
| Di Rosa, F | 1 |
| Gregori, A | 1 |
| Borea, PA | 1 |
| Antoniou, K | 1 |
| Galanopoulos, A | 1 |
| Vlachou, S | 1 |
| Kourouli, T | 1 |
| Nahmias, V | 1 |
| Thermos, K | 1 |
| Panagis, G | 1 |
| Daifoti, Z | 1 |
| Marselos, M | 1 |
| Papahatjis, D | 1 |
| Spyraki, C | 1 |
| McMahon, LR | 1 |
| Koek, W | 1 |
| Kalbasi Anaraki, D | 1 |
| Sianati, S | 1 |
| Sadeghi, M | 1 |
| Ghasemi, M | 1 |
| Paydar, MJ | 1 |
| Javadi, P | 1 |
| Ejtemaei Mehr, S | 1 |
| Dehpour, AR | 1 |
Other Studies
5 other studies available for am 251 and Anochlesia
| Article | Year |
|---|---|
Novel halogenated derivates of JWH-018: Behavioral and binding studies in mice.
Topics: Animals; Binding, Competitive; Cannabinoid Receptor Agonists; Cannabinoids; Catalepsy; CHO Cells; Cr | 2015 |
Effect of the novel synthetic cannabinoids AKB48 and 5F-AKB48 on "tetrad", sensorimotor, neurological and neurochemical responses in mice. In vitro and in vivo pharmacological studies.
Topics: Adamantane; Aggression; Animals; Behavior, Animal; Binding, Competitive; Cannabinoid Receptor Agonis | 2016 |
Behavioral pharmacological properties of a novel cannabinoid 1',1'-dithiolane delta8-THC analog, AMG-3.
Topics: Animals; Behavior, Animal; Binding, Competitive; Cannabinoids; Catalepsy; Cell Membrane; Cerebral Co | 2005 |
Differences in the relative potency of SR 141716A and AM 251 as antagonists of various in vivo effects of cannabinoid agonists in C57BL/6J mice.
Topics: Animals; Benzoxazines; Cannabinoids; Catalepsy; Dose-Response Relationship, Drug; Dronabinol; Hypoth | 2007 |
Modulation by female sex hormones of the cannabinoid-induced catalepsy and analgesia in ovariectomized mice.
Topics: Analgesics; Animals; Behavior, Animal; Benzoxazines; Cannabinoids; Catalepsy; Dose-Response Relation | 2008 |