am 251 and Amnesia
am 251 has been researched along with Amnesia in 4 studies
AM 251: an analog of SR141716A; structure given in first source
AM-251 : A carbohydrazide obtained by formal condensation of the carboxy group of 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid with the amino group of 1-aminopiperidine. An antagonist at the CB1 cannabinoid receptor.
Amnesia: Pathologic partial or complete loss of the ability to recall past experiences (AMNESIA, RETROGRADE) or to form new memories (AMNESIA, ANTEROGRADE). This condition may be of organic or psychologic origin. Organic forms of amnesia are usually associated with dysfunction of the DIENCEPHALON or HIPPOCAMPUS. (From Adams et al., Principles of Neurology, 6th ed, pp426-7)
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " Such insights prompted us to investigate the influence of dorsal hippocampal (CA1) NMDA receptor agents on amnesia induced by cannabinoid CB1 receptor agonist, arachidonylcyclopropylamide (ACPA) in male mice." | 3.81 | The dual effect of CA1 NMDA receptor modulation on ACPA-induced amnesia in step-down passive avoidance learning task. ( Amin-Yavari, S; Ebrahimi-Ghiri, M; Nasehi, M; Torabi-Nami, M; Zarrindast, MR, 2015) |
Research
Studies (4)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Nasehi, M | 1 |
| Amin-Yavari, S | 1 |
| Ebrahimi-Ghiri, M | 1 |
| Torabi-Nami, M | 1 |
| Zarrindast, MR | 2 |
| Mohammadmirzaei, N | 1 |
| Rezayof, A | 2 |
| Ghasemzadeh, Z | 1 |
| García-Gutiérrez, MS | 1 |
| Manzanares, J | 1 |
| Alijanpour, S | 1 |
Other Studies
4 other studies available for am 251 and Amnesia
| Article | Year |
|---|---|
The dual effect of CA1 NMDA receptor modulation on ACPA-induced amnesia in step-down passive avoidance learning task.
Topics: 2-Amino-5-phosphonovalerate; Amnesia; Analysis of Variance; Animals; Arachidonic Acids; Avoidance Le | 2015 |
Activation of cannabinoid CB1 receptors in the ventral hippocampus improved stress-induced amnesia in rat.
Topics: Amnesia; Animals; Arachidonic Acids; Hippocampus; Male; Memory Consolidation; Piperidines; Pyrazoles | 2016 |
The cannabinoid CB1 receptor is involved in the anxiolytic, sedative and amnesic actions of benzodiazepines.
Topics: Alprazolam; Amnesia; Amygdala; Animals; Anti-Anxiety Agents; Anxiety; Avoidance Learning; Behavior, | 2010 |
Dorsal hippocampal cannabinoid CB1 receptors mediate the interactive effects of nicotine and ethanol on passive avoidance learning in mice.
Topics: Amnesia; Analysis of Variance; Animals; Arachidonic Acids; Avoidance Learning; CA1 Region, Hippocamp | 2013 |