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am 251 and Amnesia

am 251 has been researched along with Amnesia in 4 studies

AM 251: an analog of SR141716A; structure given in first source
AM-251 : A carbohydrazide obtained by formal condensation of the carboxy group of 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid with the amino group of 1-aminopiperidine. An antagonist at the CB1 cannabinoid receptor.

Amnesia: Pathologic partial or complete loss of the ability to recall past experiences (AMNESIA, RETROGRADE) or to form new memories (AMNESIA, ANTEROGRADE). This condition may be of organic or psychologic origin. Organic forms of amnesia are usually associated with dysfunction of the DIENCEPHALON or HIPPOCAMPUS. (From Adams et al., Principles of Neurology, 6th ed, pp426-7)

Research Excerpts

ExcerptRelevanceReference
" Such insights prompted us to investigate the influence of dorsal hippocampal (CA1) NMDA receptor agents on amnesia induced by cannabinoid CB1 receptor agonist, arachidonylcyclopropylamide (ACPA) in male mice."3.81The dual effect of CA1 NMDA receptor modulation on ACPA-induced amnesia in step-down passive avoidance learning task. ( Amin-Yavari, S; Ebrahimi-Ghiri, M; Nasehi, M; Torabi-Nami, M; Zarrindast, MR, 2015)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nasehi, M1
Amin-Yavari, S1
Ebrahimi-Ghiri, M1
Torabi-Nami, M1
Zarrindast, MR2
Mohammadmirzaei, N1
Rezayof, A2
Ghasemzadeh, Z1
García-Gutiérrez, MS1
Manzanares, J1
Alijanpour, S1

Other Studies

4 other studies available for am 251 and Amnesia

ArticleYear
The dual effect of CA1 NMDA receptor modulation on ACPA-induced amnesia in step-down passive avoidance learning task.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2015, Volume: 25, Issue:4

    Topics: 2-Amino-5-phosphonovalerate; Amnesia; Analysis of Variance; Animals; Arachidonic Acids; Avoidance Le

2015
Activation of cannabinoid CB1 receptors in the ventral hippocampus improved stress-induced amnesia in rat.
    Brain research, 2016, 09-01, Volume: 1646

    Topics: Amnesia; Animals; Arachidonic Acids; Hippocampus; Male; Memory Consolidation; Piperidines; Pyrazoles

2016
The cannabinoid CB1 receptor is involved in the anxiolytic, sedative and amnesic actions of benzodiazepines.
    Journal of psychopharmacology (Oxford, England), 2010, Volume: 24, Issue:5

    Topics: Alprazolam; Amnesia; Amygdala; Animals; Anti-Anxiety Agents; Anxiety; Avoidance Learning; Behavior,

2010
Dorsal hippocampal cannabinoid CB1 receptors mediate the interactive effects of nicotine and ethanol on passive avoidance learning in mice.
    Addiction biology, 2013, Volume: 18, Issue:2

    Topics: Amnesia; Analysis of Variance; Animals; Arachidonic Acids; Avoidance Learning; CA1 Region, Hippocamp

2013