Page last updated: 2024-10-22

am 251 and Albuminuria

am 251 has been researched along with Albuminuria in 2 studies

AM 251: an analog of SR141716A; structure given in first source
AM-251 : A carbohydrazide obtained by formal condensation of the carboxy group of 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid with the amino group of 1-aminopiperidine. An antagonist at the CB1 cannabinoid receptor.

Albuminuria: The presence of albumin in the urine, an indicator of KIDNEY DISEASES.

Research Excerpts

ExcerptRelevanceReference
"In experimental type 1 diabetes, the CB1 receptor is overexpressed by glomerular podocytes, and blockade of the CB1 receptor ameliorates albuminuria possibly via prevention of nephrin, podocin, and ZO-1 loss."3.76Cannabinoid receptor 1 blockade ameliorates albuminuria in experimental diabetic nephropathy. ( Barutta, F; Corbelli, A; Di Marzo, V; Gambino, R; Gruden, G; Mastrocola, R; Perin, PC; Pinach, S; Rastaldi, MP, 2010)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jenkin, KA1
O'Keefe, L1
Simcocks, AC1
Grinfeld, E1
Mathai, ML1
McAinch, AJ1
Hryciw, DH1
Barutta, F1
Corbelli, A1
Mastrocola, R1
Gambino, R1
Di Marzo, V1
Pinach, S1
Rastaldi, MP1
Perin, PC1
Gruden, G1

Other Studies

2 other studies available for am 251 and Albuminuria

ArticleYear
Chronic administration of AM251 improves albuminuria and renal tubular structure in obese rats.
    The Journal of endocrinology, 2015, Volume: 225, Issue:2

    Topics: Albuminuria; Animals; Collagen; Diet, High-Fat; Humans; Kidney Tubules; Male; Obesity; Piperidines;

2015
Cannabinoid receptor 1 blockade ameliorates albuminuria in experimental diabetic nephropathy.
    Diabetes, 2010, Volume: 59, Issue:4

    Topics: Albuminuria; Animals; Connective Tissue Growth Factor; Diabetes Mellitus, Experimental; Diabetic Nep

2010