am 251 has been researched along with Age-Related Memory Disorders in 15 studies
AM 251: an analog of SR141716A; structure given in first source
AM-251 : A carbohydrazide obtained by formal condensation of the carboxy group of 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid with the amino group of 1-aminopiperidine. An antagonist at the CB1 cannabinoid receptor.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Like emotional symptoms such as anxiety, modulations in working memory are among the frequently-reported but controversial psychiatric symptoms associated with nicotine (NC) administration." | 7.79 | Working memory- and anxiety-related behavioral effects of repeated nicotine as a stressor: the role of cannabinoid receptors. ( Hayase, T, 2013) |
| "Like emotional symptoms such as anxiety, modulations in working memory are among the frequently-reported but controversial psychiatric symptoms associated with nicotine (NC) administration." | 3.79 | Working memory- and anxiety-related behavioral effects of repeated nicotine as a stressor: the role of cannabinoid receptors. ( Hayase, T, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (13.33) | 29.6817 |
| 2010's | 11 (73.33) | 24.3611 |
| 2020's | 2 (13.33) | 2.80 |
| Authors | Studies |
|---|---|
| Rezaie, M | 1 |
| Nasehi, M | 4 |
| Vaseghi, S | 1 |
| Alimohammadzadeh, K | 1 |
| Islami Vaghar, M | 1 |
| Mohammadi-Mahdiabadi-Hasani, MH | 1 |
| Zarrindast, MR | 4 |
| Zhang, R | 1 |
| Lao, K | 1 |
| Lu, B | 1 |
| Guo, H | 1 |
| Cheng, J | 1 |
| Chen, P | 1 |
| Gou, X | 1 |
| Ito, S | 1 |
| Deyama, S | 1 |
| Domoto, M | 1 |
| Zhang, T | 1 |
| Sasase, H | 1 |
| Fukao, A | 1 |
| Esaki, H | 1 |
| Hinoi, E | 1 |
| Kaneko, S | 1 |
| Kaneda, K | 1 |
| Rasekhi, K | 1 |
| Oryan, S | 2 |
| Khodayar, E | 1 |
| Nedaei, SE | 1 |
| Rezayof, A | 1 |
| Pourmotabbed, A | 1 |
| Zhang, RS | 1 |
| He, Z | 1 |
| Jin, WD | 1 |
| Wang, R | 1 |
| Kruk-Slomka, M | 1 |
| Budzynska, B | 1 |
| Slomka, T | 1 |
| Banaszkiewicz, I | 1 |
| Biala, G | 1 |
| Maćkowiak, M | 2 |
| Chocyk, A | 2 |
| Dudys, D | 1 |
| Wedzony, K | 2 |
| Nawata, Y | 1 |
| Hiranita, T | 1 |
| Yamamoto, T | 1 |
| Baek, JH | 1 |
| Zheng, Y | 1 |
| Darlington, CL | 1 |
| Smith, PF | 1 |
| Dillon, GM | 1 |
| Lubbers, LS | 1 |
| Ferguson, MT | 1 |
| Lao, JZ | 1 |
| Huang, RR | 1 |
| Xiao, JC | 1 |
| Fong, TM | 1 |
| Hale, JJ | 1 |
| Rupprecht, K | 1 |
| Miao, S | 1 |
| Rowe, BA | 1 |
| Kornecook, TJ | 1 |
| Dodart, JC | 1 |
| Haghani, M | 1 |
| Shabani, M | 1 |
| Javan, M | 1 |
| Motamedi, F | 1 |
| Janahmadi, M | 1 |
| Hayase, T | 1 |
| Markowicz-Kula, K | 1 |
15 other studies available for am 251 and Age-Related Memory Disorders
| Article | Year |
|---|---|
The interaction effect of sleep deprivation and cannabinoid type 1 receptor in the CA1 hippocampal region on passive avoidance memory, depressive-like behavior and locomotor activity in rats.
Topics: Animals; Arachidonic Acids; Avoidance Learning; Behavior, Animal; CA1 Region, Hippocampal; Cannabino | 2021 |
(m)RVD-hemopressin (α) and (m)VD-hemopressin (α) improve the memory-impairing effect of scopolamine in novel object and object location recognition tasks in mice.
Topics: Alzheimer Disease; Animals; Cognitive Dysfunction; Disease Models, Animal; Endocannabinoids; Hemoglo | 2021 |
Effects of the synthetic cannabinoid 5F-AMB on anxiety and recognition memory in mice.
Topics: Animals; Anxiety; Cannabinoids; Male; Memory Disorders; Mice; Mice, Inbred C57BL; Piperidines; Prefr | 2019 |
Involvement of the nucleus accumbens shell glutamatergic system in ACPA-induced impairment of inhibitory avoidance memory consolidation.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arachidonic Acids; Avoidance Learning; Cannabinoid Receptor Ag | 2014 |
Effect of nucleus accumbens shell 5-HT4 receptors on the impairment of ACPA-induced emotional memory consolidation in male Wistar rats.
Topics: Aniline Compounds; Animals; Arachidonic Acids; Cannabinoid Receptor Antagonists; Disease Models, Ani | 2016 |
Activation of endocannabinoid system in the rat basolateral amygdala improved scopolamine-induced memory consolidation impairment.
Topics: Animals; Arachidonic Acids; Avoidance Learning; Basolateral Nuclear Complex; Cannabinoid Receptor Ag | 2016 |
Effects of the cannabinoid 1 receptor peptide ligands hemopressin, (m)RVD-hemopressin(α) and (m)VD-hemopressin(α) on memory in novel object and object location recognition tasks in normal young and Aβ1-42-treated mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Behavior, Animal; Benzoxazines; Cannabinoid Recep | 2016 |
The Influence of the CB1 Receptor Ligands on the Schizophrenia-Like Effects in Mice Induced by MK-801.
Topics: Animals; Antipsychotic Agents; Cannabinoid Receptor Modulators; Disease Models, Animal; Dizocilpine | 2016 |
Activation of CB1 cannabinoid receptors impairs memory consolidation and hippocampal polysialylated neural cell adhesion molecule expression in contextual fear conditioning.
Topics: Animals; Conditioning, Psychological; Dentate Gyrus; Doublecortin Domain Proteins; Doublecortin Prot | 2009 |
A cannabinoid CB(1) receptor antagonist ameliorates impairment of recognition memory on withdrawal from MDMA (Ecstasy).
Topics: Analysis of Variance; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Admini | 2010 |
Evidence that spatial memory deficits following bilateral vestibular deafferentation in rats are probably permanent.
Topics: Analysis of Variance; Animals; Behavior, Animal; Benzoxazines; Cannabinoids; Exploratory Behavior; M | 2010 |
MK-7128, a novel CB1 receptor inverse agonist, improves scopolamine-induced learning and memory deficits in mice.
Topics: Animals; Azetidines; Cerebral Cortex; Cognition Disorders; Disease Models, Animal; Dose-Response Rel | 2011 |
CB1 cannabinoid receptor activation rescues amyloid β-induced alterations in behaviour and intrinsic electrophysiological properties of rat hippocampal CA1 pyramidal neurones.
Topics: Action Potentials; Amyloid beta-Peptides; Animals; Avoidance Learning; Behavior, Animal; Benzoxazine | 2012 |
Working memory- and anxiety-related behavioral effects of repeated nicotine as a stressor: the role of cannabinoid receptors.
Topics: Analysis of Variance; Animals; Anxiety; Brain; Disease Models, Animal; Dose-Response Relationship, D | 2013 |
Acute activation of CB1 cannabinoid receptors transiently decreases PSA-NCAM expression in the dentate gyrus of the rat hippocampus.
Topics: Animals; Cannabinoids; Cell Count; Cell Differentiation; Cell Proliferation; Dentate Gyrus; Dose-Res | 2007 |