alverine has been researched along with Abdominal Pain in 4 studies
alverine : A tertiary amine having one ethyl and two 3-phenylprop-1-yl groups attached to the nitrogen. An antispasmodic that acts directly on intestinal and uterine smooth muscle, it is used (particularly as the citrate salt) in the treatment of irritable bowel syndrome.
Abdominal Pain: Sensation of discomfort, distress, or agony in the abdominal region.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the efficacy of alverine citrate and simeticone combination in patients with IBS-related abdominal pain/discomfort." | 9.14 | Clinical trial: the efficacy of alverine citrate/simeticone combination on abdominal pain/discomfort in irritable bowel syndrome--a randomized, double-blind, placebo-controlled study. ( Andro Delestrain, MC; Bueno, L; Ducrotté, P; Paradowski, L; Wittmann, T, 2010) |
| "To evaluate the efficacy of alverine citrate and simeticone combination in patients with IBS-related abdominal pain/discomfort." | 5.14 | Clinical trial: the efficacy of alverine citrate/simeticone combination on abdominal pain/discomfort in irritable bowel syndrome--a randomized, double-blind, placebo-controlled study. ( Andro Delestrain, MC; Bueno, L; Ducrotté, P; Paradowski, L; Wittmann, T, 2010) |
| "The severity and frequency of abdominal pain improved in 66% and 68% of patients treated with alverine citrate vs." | 5.10 | Alverine citrate fails to relieve the symptoms of irritable bowel syndrome: results of a double-blind, randomized, placebo-controlled trial. ( Chapman, RW; Mee, AS; Mitchell, SA; Palmer, KR; Smith, GD, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ducrotte, P | 2 |
| Grimaud, JC | 1 |
| Dapoigny, M | 1 |
| Personnic, S | 1 |
| O'Mahony, V | 1 |
| Andro-Delestrain, MC | 1 |
| Wittmann, T | 1 |
| Paradowski, L | 1 |
| Bueno, L | 1 |
| Andro Delestrain, MC | 1 |
| Ford, AC | 1 |
| Mitchell, SA | 1 |
| Mee, AS | 1 |
| Smith, GD | 1 |
| Palmer, KR | 1 |
| Chapman, RW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Assessment of On-demand MeteoSpasmyl® Use Effectiveness in Irritable Bowel Syndrome[NCT01404923] | Phase 4 | 436 participants (Actual) | Interventional | 2009-12-31 | Completed | ||
| The Role of Irritable Bowel Syndrome in Lactose Intolerance (LION Trial): Protocol of a Multicentre Randomized Controlled Clinical Trial[NCT05100719] | 200 participants (Anticipated) | Interventional | 2022-09-30 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Irritable Bowel Syndrome Quality of Life total score (IBSQoL) is a health-related Quality of Life (QoL) disease-specific scale adapted for French patients. Total score ranges from minimum=0 to maximum = 100 representing the best outcome. (NCT01404923)
Timeframe: Baseline and 6 months
| Intervention | units on a scale (Mean) |
|---|---|
| Meteospasmyl | 13.8 |
| Standard of Care | 8.4 |
Improvement of the total IBSQoL scores from baseline to month 6 calculated in percentage (NCT01404923)
Timeframe: Baseline and 6 Months
| Intervention | % of improvement of IBSQoL total scores (Mean) |
|---|---|
| Meteospasmyl | 28.5 |
| Standard of Care | 18.6 |
3 trials available for alverine and Abdominal Pain
| Article | Year |
|---|---|
On-demand treatment with alverine citrate/simeticone compared with standard treatments for irritable bowel syndrome: results of a randomised pragmatic study.
Topics: Abdominal Pain; Antifoaming Agents; Double-Blind Method; Drug Combinations; Female; Humans; Irritabl | 2014 |
On-demand treatment with alverine citrate/simeticone compared with standard treatments for irritable bowel syndrome: results of a randomised pragmatic study.
Topics: Abdominal Pain; Antifoaming Agents; Double-Blind Method; Drug Combinations; Female; Humans; Irritabl | 2014 |
On-demand treatment with alverine citrate/simeticone compared with standard treatments for irritable bowel syndrome: results of a randomised pragmatic study.
Topics: Abdominal Pain; Antifoaming Agents; Double-Blind Method; Drug Combinations; Female; Humans; Irritabl | 2014 |
On-demand treatment with alverine citrate/simeticone compared with standard treatments for irritable bowel syndrome: results of a randomised pragmatic study.
Topics: Abdominal Pain; Antifoaming Agents; Double-Blind Method; Drug Combinations; Female; Humans; Irritabl | 2014 |
Clinical trial: the efficacy of alverine citrate/simeticone combination on abdominal pain/discomfort in irritable bowel syndrome--a randomized, double-blind, placebo-controlled study.
Topics: Abdominal Pain; Adolescent; Adult; Aged; Antifoaming Agents; Double-Blind Method; Drug Combinations; | 2010 |
Alverine citrate fails to relieve the symptoms of irritable bowel syndrome: results of a double-blind, randomized, placebo-controlled trial.
Topics: Abdomen; Abdominal Pain; Administration, Oral; Adult; Aged; Colonic Diseases, Functional; Double-Bli | 2002 |
1 other study available for alverine and Abdominal Pain
| Article | Year |
|---|---|
Alverine citrate, simeticone, and Rome III irritable bowel syndrome.
Topics: Abdominal Pain; Antifoaming Agents; Drug Therapy, Combination; Humans; Irritable Bowel Syndrome; Met | 2010 |