aluminum-tetrasulfophthalocyanine and Rhabdomyosarcoma

aluminum-tetrasulfophthalocyanine has been researched along with Rhabdomyosarcoma* in 1 studies

Other Studies

1 other study(ies) available for aluminum-tetrasulfophthalocyanine and Rhabdomyosarcoma

Article	Year
Study of low doses cisplatin synergistic effect on photodynamic outcome of aluminum phythalocyanine on soft tissue sarcoma (RD) cell line. Photodiagnosis and photodynamic therapy, 2015, Volume: 12, Issue:1 Photodynamic therapy (PDT) in combination with other treatment modality expects to overcome the drug resistance experienced in monotherapy. In this present work combination of chemo cum PDT is studied over the range of doses. It is found that treating cells/exposing cells to chemo drug (cisplatin, CDDP) and PDT individually results in minimal cell killing (∼7% and ∼16%) compared to the administration of chemo followed by PDT (∼50% cells were viable). These results showed that cell viability synergistically decreases in case of combination treatment as compared with individual treatment. Photodynamic therapy (PDT) in combination with CDDP chemotherapy expects to overcome the drug resistance experienced in monotherapy. Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; Cisplatin; Dose-Response Relationship, Drug; Drug Synergism; Humans; Indoles; Organometallic Compounds; Photochemotherapy; Photosensitizing Agents; Rhabdomyosarcoma; Treatment Outcome	2015

Article

Year

Study of low doses cisplatin synergistic effect on photodynamic outcome of aluminum phythalocyanine on soft tissue sarcoma (RD) cell line.

Photodiagnosis and photodynamic therapy, 2015, Volume: 12, Issue:1

Photodynamic therapy (PDT) in combination with other treatment modality expects to overcome the drug resistance experienced in monotherapy. In this present work combination of chemo cum PDT is studied over the range of doses. It is found that treating cells/exposing cells to chemo drug (cisplatin, CDDP) and PDT individually results in minimal cell killing (∼7% and ∼16%) compared to the administration of chemo followed by PDT (∼50% cells were viable). These results showed that cell viability synergistically decreases in case of combination treatment as compared with individual treatment. Photodynamic therapy (PDT) in combination with CDDP chemotherapy expects to overcome the drug resistance experienced in monotherapy.

Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; Cisplatin; Dose-Response Relationship, Drug; Drug Synergism; Humans; Indoles; Organometallic Compounds; Photochemotherapy; Photosensitizing Agents; Rhabdomyosarcoma; Treatment Outcome

2015