aluminum-tetrasulfophthalocyanine and Burkitt-Lymphoma

aluminum-tetrasulfophthalocyanine has been researched along with Burkitt-Lymphoma* in 1 studies

Other Studies

1 other study(ies) available for aluminum-tetrasulfophthalocyanine and Burkitt-Lymphoma

Article	Year
Spin-trapping of free radicals during phthalocyanine photosensitization of lymphoma cells in vitro. Cancer biochemistry biophysics, 1992, Volume: 13, Issue:2 Spin-trapping and electron spin resonance (ESR) spectroscopy were used to detect free radicals generated during light exposure of lymphoma cells sensitized in vitro by metallotetrasulfophthalocyanines (Al-PcS4 and Zn-PcS4). 5,5-dimethyl-1-pyrroline-1-oxide (DMPO) and alpha-phenyl-beta-tert-butylnitrone (PBN) were used as spin-trapping agents. Hydroxyl radical spin-adducts were detected under conditions of both extracellular and intracellular photosensitization. In addition, organic radicals of different origin and/or variable yields were trapped, depending on the photosensitization conditions and the spin-trap used. For comparison, analogous experiments were carried out with another tumor-localizing photosensitizer, Photofrin II. Topics: Burkitt Lymphoma; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Extracellular Space; Free Radicals; Humans; Indoles; Intracellular Fluid; Nitrogen Oxides; Organometallic Compounds; Photochemotherapy; Radiation-Sensitizing Agents; Spin Labels; Tumor Cells, Cultured	1992

Article

Year

Spin-trapping of free radicals during phthalocyanine photosensitization of lymphoma cells in vitro.

Cancer biochemistry biophysics, 1992, Volume: 13, Issue:2

Spin-trapping and electron spin resonance (ESR) spectroscopy were used to detect free radicals generated during light exposure of lymphoma cells sensitized in vitro by metallotetrasulfophthalocyanines (Al-PcS4 and Zn-PcS4). 5,5-dimethyl-1-pyrroline-1-oxide (DMPO) and alpha-phenyl-beta-tert-butylnitrone (PBN) were used as spin-trapping agents. Hydroxyl radical spin-adducts were detected under conditions of both extracellular and intracellular photosensitization. In addition, organic radicals of different origin and/or variable yields were trapped, depending on the photosensitization conditions and the spin-trap used. For comparison, analogous experiments were carried out with another tumor-localizing photosensitizer, Photofrin II.

Topics: Burkitt Lymphoma; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Extracellular Space; Free Radicals; Humans; Indoles; Intracellular Fluid; Nitrogen Oxides; Organometallic Compounds; Photochemotherapy; Radiation-Sensitizing Agents; Spin Labels; Tumor Cells, Cultured

1992