Page last updated: 2024-08-22

aluminum sulfate and 2019 Novel Coronavirus Disease

aluminum sulfate has been researched along with 2019 Novel Coronavirus Disease in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's34 (100.00)2.80

Authors

AuthorsStudies
An, J; Bao, L; Cao, X; Ding, L; Fan, J; Gu, C; Hu, D; Hu, Z; Huang, C; Jiang, Y; Li, J; Liu, G; Liu, H; Liu, J; Liu, Y; Miao, C; Song, Y; Wang, D; Xie, Y; Xu, J; Yan, H; Yang, Y; Yu, P; Zhang, C; Zhang, L; Zhou, C; Zhou, L; Zhu, H; Zhu, Q; Zhu, Y1
Liu, DB; Liu, ZG; Luo, XQ; Ma, K; Mo, LH; Shao, JB; Yang, PC; Zhang, GH; Zhang, HP1
Alberto, ER; Ambrosino, D; Baccarini, C; Badat, A; Bhorat, QE; Borja-Tabora, C; Bravo, L; Brochado, L; Buntinx, E; Carlos, J; Cerbino-Neto, J; Clemens, R; Clemens, SAC; de Los Reyes, MRA; de Salazar, DIM; Engelbrecht, J; Han, HH; Hernández, EA; Hites, M; Hosain, R; Hu, B; Jurgens, J; Li, P; Liang, J; Lopez, P; López-Medina, E; Luz, KG; Martinot, JB; Medina, T; Montellano, MEB; Paiva, MS; Panaligan, MM; Quinsaat, A; Reynales, H; Richmond, P; Roa, C; Rockhold, F; Rodríguez, CA; Rodriguez, EJ; Salvani-Bautista, M; Schwarzbold, AV; Siber, G; Smolenov, I; Sprinz, E; Toloza, LB; Velasquez, H; Yu, CY1
Ebihara, T; Fujita, R; Hino, M; Kakino, K; Karasaki, N; Kato, Y; Kusakabe, T; Lee, JM; Masuda, A; Miyata, T; Mon, H; Moriyama, T; Nagasato, T; Nakashima, A; Nakatake, H; Nishida, M; Oyama, K; Sakurai, Y; Sato, K; Suzuki, K; Takahashi, D; Tanaka, M; Tonooka, Y; Ueda, T; Yasuda, J1
Cao, H; Lin, K; Liu, C; Luan, N; Wang, Y1
Ding, D; Feng, RR; Gong, R; Guo, J; He, CB; Li, YT; Liu, YL; Lu, J; Wang, J; Wei, HW; Wen, Y; Yang, GF; Yin, XG; Zhang, HW; Zhang, RY; Zhou, SH1
Alcain, J; Álvarez, DE; Auguste, AJ; Bruno, LA; Cassataro, J; Castro, EF; Chemes, LB; Coria, LM; Darriba, ML; Mazzitelli, I; Pasquevich, KA; Pérez, PS; Pueblas Castro, C; Salvatori, M; Saposnik, LM; Stone, WB; Varese, A1
Amaishi, Y; Arase, H; Chono, H; Ehara, T; Hayashi, H; Ide, R; Ju, N; Kawabata, S; Komatsuno, T; Kubota-Koketsu, R; Matsuura, Y; Mineno, J; Morishita, R; Nakagami, H; Nakamaru, R; Okamoto, S; Ono, C; Otera, T; Rakugi, H; Saito, Y; Sakaguchi, M; Shimamura, M; Shioda, T; Sun, J; Tenma, A; Tomioka, H; Yanagida, Y; Yoshida, S1
Adhikari, R; Chen, WH; Elena Bottazzi, M; Gillespie, PM; Hotez, PJ; Jose Villar, M; Keegan, B; Kimata, JT; Kundu, R; Lee, J; Liu, Z; Lopez, B; Paradkar, V; Pollet, J; Poveda, C; Rani Thimmiraju, S; Reers, M; Ronca, S; Strych, U; Versteeg, L; Wei, J; Zhan, B1
Abreu, DPB; Alvim, RGF; Conde, L; da Fonseca-Martins, AM; de Matos Guedes, HL; de Oliveira, AC; Dos-Santos, JS; Dumard, CH; Ferreira, JRM; Ferreira, OC; Filardy, AD; Firmino-Cruz, L; Gomes, AMO; Guedes-da-Silva, FH; Guimarães-Pinto, K; Leandro, MDS; Lima, TM; Marsili, FF; Mohana Borges, RDS; Oliveira-Maciel, D; Perez, GG; Rodrigues, DAS; Roncaglia-Pereira, VA; Rossi-Bergmann, B; Santos, ACV; Silva, JL; Silva, MVM; Souza, TML; Tanuri, A; Vale, AM1
Barbier, M; Batwal, S; Bevere, JR; Chandrasekaran, R; Cooper, M; Cyphert, HA; Dalvie, NC; Damron, FH; Johnston, RS; Kang, J; Lee, KS; Lothe, R; Love, JC; Martinez, I; Miller, OA; Nagar, G; Rader, NA; Rajurkar, M; Rao, H; Rodriguez-Aponte, SA; Russ, BP; Shaligram, U; Winters, MT; Wong, TY; Wong, ZY1
Ainai, A; Hasegawa, H; Hashiguchi, T; Hemmi, T; Iida, S; Iwata-Yoshikawa, N; Kanno, T; Miyamoto, S; Nagata, N; Saito, S; Sano, K; Sato, Y; Shiwa-Sudo, N; Suzuki, R; Suzuki, T; Tamura, K; Tobiume, M; Ueno, A1
Chen, Z; Chow, HY; Dai, L; Dong, B; Dong, X; Gan, C; Gong, Y; Li, W; Li, Y; Liu, Y; Qi, S; Tang, D; Tang, J; Valencia, CA; Wang, Y; Yang, L; Yang, Q; Zhang, T; Zhao, D1
Çelik, G; İnçeh, FN; Keser, D; Özcengiz, E; Özcengiz, G; Özkul, A1
Huang, H; Liu, Z; Quan, Q; Xiong, X; Yu, M; Zheng, X; Zhou, Z1
Darvish, M; Fatemi, F; Khatibi, A; Moosavi-Nejad, Z; Siadat, SOR1
Fox, CB; Jongkaewwattana, A; Khorattanakulchai, N; Malaivijitnond, S; Manopwisedjaroen, S; Phoolcharoen, W; Pichyangkul, S; Praserthsee, W; Shanmugaraj, B; Srisutthisamphan, K; Sunyakumthorn, P; Taepavarapruk, P; Taychakhoonavudh, S; Thitithanyanont, A; Tomai, M1
Andersen, H; Bekele, Y; Berzofsky, JA; Hoang, T; Kar, S; Lewis, MG; Li, J; Sui, Y1
Arunachalam, PS; Cheng, YC; Do, J; Feinberg, MB; Fontenot, J; Friedland, N; Hanson, C; Hu, M; Joshi, SB; Kim, PS; Kumru, OS; Morris, MK; Pulendran, B; Sanyal, M; Shirreff, L; Tang, S; Vasudevan, G; Villinger, FJ; Volkin, DB; Weidenbacher, PA1
Abuna, RPF; Andrade, JM; Báfica, A; da Silva, JS; de Araujo, ACVSC; de Magalhães, MTQ; Dias, GBM; Fabri, VMR; Heck, N; Homan, EJ; Leite, LCC; Mambelli, F; Mansur, DS; Marinho, FV; Mendes, DAGB; Oliveira, SC; Santos, BPO1
Appel, EA; Baillet, J; Bruun, TUJ; King, NP; Ou, BS; Saouaf, OM; Yan, J; Zhou, X1
Babayeva, M; Fomin, G; Petrovsky, N; Renu, S; Renukaradhya, GJ; Solomadin, M; Tabynov, K; Turebekov, N; Yadagiri, G; Yerubayev, T1
Bai, S; Chen, W; Kang, Y; Lv, M; Wang, J; Wu, J; Xie, H; Zhang, L; Zhao, W1
Chen, Z; Guo, J; Li, B; Li, Y; Liao, W; Lin, F; Lu, J; Lv, S; Meng, S; Pang, D; Shen, S; Wan, X; Wang, W; Wang, Z; Wu, J; Yang, A; Yang, D; Yang, J1
Fan, Z; Feng, S; Ha, Z; Jin, N; Liang, M; Lu, H; Ma, S; Xie, Y; Zhang, H; Zhou, K1
Chen, JJ; Cui, TT; Feng, GW; Han, X; He, P; Hu, ZY; Huang, LL; Huang, Z; Jiang, ZW; Lan, QY; Li, K; Liu, G; Ni, L; Wang, CF; Wang, ZF; Xie, ZQ; Yan, YQ; Yang, Q; Yang, SY; Yang, YZ; Yu, BW; Yuan, L; Zhao, JC; Zhou, LY1
Bajoria, S; Berman, K; Doering, J; Hickey, JM; Joshi, SB; Kaur, K; Kleanthous, H; Kumru, OS; Lien, H; Mantis, NJ; Richardson, C; Van Slyke, G; Volkin, DB1
Cao, H; Liu, C; Wang, L; Wang, Y1
Cao, F; Dai, L; Gao, XD; Ma, G; Peng, S; Xia, Y; Yan, J1
Lodaya, RN; Lofano, G; O'Hagan, DT1
Alter, G; Arunachalam, PS; Atyeo, C; Aye, P; Bohm, RP; Boyd, SD; Brunette, N; Carter, L; Coffman, RL; Doyle-Meyers, L; Dufour, J; Edara, VV; Ferrell, DE; Fiala, B; Fischinger, S; Flynn, JL; Fontenot, J; Golden, N; Gorman, MJ; Gupta, S; Hsieh, CL; Kepl, E; King, NP; Kleanthous, H; Kraft, JC; Lai, L; Li, C; Maness, NJ; McLellan, JS; Miranda, MC; Monjure, C; Montefiori, D; Murphy, M; Navarro, MJ; Novack, D; O'Hagan, DT; Pettie, D; Plante, JA; Plante, KS; Pulendran, B; Rappaport, J; Rappuoli, R; Rogers, K; Röltgen, K; Roy, C; Russell-Lodrigue, K; Shen, X; Shin, S; Shirreff, L; Spencer, S; Subramaniam, S; Suthar, MS; Sydeman, C; Trisal, M; Van Der Most, R; Veesler, D; Villinger, F; Walls, AC; White, AG; Wrenn, S; Zhu, A1
Alter, G; Amara, RR; Atyeo, C; Bollimpelli, VS; Cheedarla, N; Dinnon, KH; Edara, VV; Fischinger, S; Floyd, K; Fox, CB; Gangadhara, S; Gralinski, L; Gumber, S; Kirejczyk, S; Lai, L; Menachery, VD; Routhu, NK; Sahoo, A; Shi, PY; Shiferaw, A; Shin, SA; Styles, TM; Suthar, MS; Tomai, M; Vanderford, TH1
Abid, T; Bottazzi, ME; Chen, WH; Cohen, J; Connor-Stroud, F; Dutta, D; Easley, K; Edara, VV; Eisel, N; Ferrari, G; Floyd, K; Fox, CB; Gao, H; Gumber, S; Hotez, PJ; Jean, SM; Kasturi, SP; Kirejczyk, S; Kozlowski, PA; LaBranche, CC; Latif, MB; Lee, J; Liu, Z; Mielke, D; Montefiori, DC; Pacheco-Sanchez, G; Paiardini, M; Pereira Ribeiro, S; Pino, M; Pollara, J; Pollet, J; Sekaly, RP; Sette, A; Shen, X; Shenvi, N; Smith, JC; Stammen, RL; Strych, U; Suthar, MS; Tomai, MA; Tomaras, GD; Vanderford, TH; Wang, S; Wei, J; Weiskopf, D; Wood, JS; Zhan, B1
Amer, AO; Attia, Z; Boyaka, PN; Cormet-Boyaka, E; Ghimire, S; Kim, E; Kim, SH; Li, J; Liu, SL; Liyanage, NPM; Renukaradhya, GJ; Satoskar, AR; Shukla, RK; Steiner, HE; Woodfint, RM; Zeng, C1

Reviews

1 review(s) available for aluminum sulfate and 2019 Novel Coronavirus Disease

ArticleYear
The continued advance of vaccine adjuvants - 'we can work it out'.
    Seminars in immunology, 2020, Volume: 50

    Topics: Adjuvants, Immunologic; Alum Compounds; COVID-19; COVID-19 Vaccines; Humans; SARS-CoV-2; Systems Biology; Vaccinology

2020

Trials

2 trial(s) available for aluminum sulfate and 2019 Novel Coronavirus Disease

ArticleYear
Efficacy of the adjuvanted subunit protein COVID-19 vaccine, SCB-2019: a phase 2 and 3 multicentre, double-blind, randomised, placebo-controlled trial.
    Lancet (London, England), 2022, 01-29, Volume: 399, Issue:10323

    Topics: Adjuvants, Immunologic; Adolescent; Adult; Aged; Alum Compounds; Belgium; Brazil; Colombia; COVID-19; COVID-19 Vaccines; Double-Blind Method; Female; Humans; Male; Middle Aged; Oligodeoxyribonucleotides; Philippines; Protein Multimerization; Recombinant Proteins; Risk; SARS-CoV-2; South Africa; Spike Glycoprotein, Coronavirus; Vaccine Efficacy; Young Adult

2022
Safety, tolerability, and immunogenicity of a CpG/Alum adjuvanted SARS-CoV-2 recombinant protein vaccine (ZR202-CoV) in healthy adults: Preliminary report of a phase 1, randomized, double-blind, placebo-controlled, dose-escalation trial.
    Human vaccines & immunotherapeutics, 2023, Volume: 19, Issue:2

    Topics: Adjuvants, Immunologic; Adolescent; Adult; Antibodies, Neutralizing; Antibodies, Viral; COVID-19; COVID-19 Vaccines; Double-Blind Method; Humans; Immunogenicity, Vaccine; Middle Aged; SARS-CoV-2; Vaccines, Synthetic; Young Adult

2023

Other Studies

31 other study(ies) available for aluminum sulfate and 2019 Novel Coronavirus Disease

ArticleYear
Development of recombinant COVID-19 vaccine based on CHO-produced, prefusion spike trimer and alum/CpG adjuvants.
    Vaccine, 2021, 11-26, Volume: 39, Issue:48

    Topics: Alum Compounds; Aluminum Hydroxide; Animals; Antibodies, Neutralizing; Antibodies, Viral; CHO Cells; COVID-19; COVID-19 Vaccines; Cricetinae; Cricetulus; Humans; Mice; Pandemics; SARS-CoV-2; Spike Glycoprotein, Coronavirus

2021
Superoxide Dismutase Prevents SARS-CoV-2-Induced Plasma Cell Apoptosis and Stabilizes Specific Antibody Induction.
    Oxidative medicine and cellular longevity, 2022, Volume: 2022

    Topics: Adjuvants, Immunologic; Alcoholic Beverages; Alum Compounds; Angiotensin-Converting Enzyme 2; Animals; Antibodies, Neutralizing; Antibodies, Viral; Apoptosis; COVID-19; COVID-19 Vaccines; Heat-Shock Response; Immunization, Secondary; Immunogenicity, Vaccine; Janus Kinase 2; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Plasma Cells; Reactive Oxygen Species; SARS-CoV-2; Signal Transduction; Specific Pathogen-Free Organisms; Spike Glycoprotein, Coronavirus; STAT1 Transcription Factor; Superoxide Dismutase-1; Vaccination

2022
Optimization of SARS-CoV-2 Spike Protein Expression in the Silkworm and Induction of Efficient Protective Immunity by Inoculation With Alum Adjuvants.
    Frontiers in immunology, 2021, Volume: 12

    Topics: Adjuvants, Immunologic; Alum Compounds; Aluminum Hydroxide; Animals; Antibodies, Neutralizing; Antibodies, Viral; Bombyx; Cell Line; Chickens; Chlorocebus aethiops; COVID-19; COVID-19 Vaccines; Euglena gracilis; Euglenozoa Infections; Female; Humans; Mice; Mice, Inbred BALB C; Pandemics; SARS-CoV-2; Spike Glycoprotein, Coronavirus; Vaccination; Vero Cells

2021
Comparison of immune responses induced by two or three doses of an alum-adjuvanted inactivated SARS-CoV-2 vaccine in mice.
    Journal of medical virology, 2022, Volume: 94, Issue:5

    Topics: Alum Compounds; Animals; Antibodies, Neutralizing; Antibodies, Viral; BNT162 Vaccine; COVID-19; COVID-19 Vaccines; Humans; Immunity, Cellular; Immunoglobulin G; Mice; SARS-CoV-2; Spike Glycoprotein, Coronavirus

2022
A protein vaccine with Alum/c-GAMP/poly(I:C) rapidly boosts robust immunity against SARS-CoV-2 and variants of concern.
    Chemical communications (Cambridge, England), 2022, Mar-22, Volume: 58, Issue:24

    Topics: Adjuvants, Immunologic; Alum Compounds; Aluminum; Animals; Antibodies, Viral; COVID-19; COVID-19 Vaccines; Humans; Immunity, Cellular; Mice; Mice, Inbred BALB C; Poly I; SARS-CoV-2

2022
A Novel Bacterial Protease Inhibitor Adjuvant in RBD-Based COVID-19 Vaccine Formulations Containing Alum Increases Neutralizing Antibodies, Specific Germinal Center B Cells and Confers Protection Against SARS-CoV-2 Infection in Mice.
    Frontiers in immunology, 2022, Volume: 13

    Topics: Adjuvants, Immunologic; Alum Compounds; Animals; Antibodies, Neutralizing; Antibodies, Viral; Antibody Formation; B-Lymphocytes; Bacterial Outer Membrane Proteins; Brucella; COVID-19; COVID-19 Vaccines; Disease Resistance; Female; Germinal Center; Humans; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; SARS-CoV-2; Spike Glycoprotein, Coronavirus

2022
Preclinical study of a DNA vaccine targeting SARS-CoV-2.
    Current research in translational medicine, 2022, Volume: 70, Issue:4

    Topics: Antibodies, Neutralizing; Antibodies, Viral; COVID-19; COVID-19 Vaccines; Humans; Pandemics; SARS-CoV-2; Vaccines, DNA; Viral Vaccines

2022
Receptor-binding domain recombinant protein on alum-CpG induces broad protection against SARS-CoV-2 variants of concern.
    Vaccine, 2022, 06-09, Volume: 40, Issue:26

    Topics: Alum Compounds; Animals; Antibodies, Neutralizing; Antibodies, Viral; COVID-19; COVID-19 Serotherapy; COVID-19 Vaccines; Humans; Immunization, Passive; Mice; Recombinant Proteins; SARS-CoV-2; Spike Glycoprotein, Coronavirus

2022
Immunogenicity of SARS-CoV-2 Trimeric Spike Protein Associated to Poly(I:C) Plus Alum.
    Frontiers in immunology, 2022, Volume: 13

    Topics: Adjuvants, Immunologic; Alum Compounds; Animals; CD8-Positive T-Lymphocytes; COVID-19; COVID-19 Vaccines; Humans; Immunoglobulin G; Mice; Poly I-C; SARS-CoV-2; Spike Glycoprotein, Coronavirus; Viral Vaccines

2022
RBD-VLP Vaccines Adjuvanted with Alum or SWE Protect K18-hACE2 Mice against SARS-CoV-2 VOC Challenge.
    mSphere, 2022, 08-31, Volume: 7, Issue:4

    Topics: Alum Compounds; Animals; Antibodies, Viral; COVID-19; COVID-19 Vaccines; Emulsions; gamma-Globulins; Hepatitis B Surface Antigens; Humans; Melphalan; Mice; Mice, Inbred BALB C; mRNA Vaccines; Pandemics; RNA, Messenger; RNA, Viral; SARS-CoV-2; Squalene; Vaccines, Synthetic; Vaccines, Virus-Like Particle; Water

2022
Intranasal vaccination induced cross-protective secretory IgA antibodies against SARS-CoV-2 variants with reducing the potential risk of lung eosinophilic immunopathology.
    Vaccine, 2022, 09-29, Volume: 40, Issue:41

    Topics: Adjuvants, Immunologic; Administration, Intranasal; Alum Compounds; Animals; Antibodies, Neutralizing; Antibodies, Viral; COVID-19; COVID-19 Vaccines; Humans; Immunoglobulin A, Secretory; Immunoglobulin G; Lung; Mice; Oligonucleotides; SARS-CoV-2; Spike Glycoprotein, Coronavirus; Vaccination

2022
A vaccine based on the yeast-expressed receptor-binding domain (RBD) elicits broad immune responses against SARS-CoV-2 variants.
    Frontiers in immunology, 2022, Volume: 13

    Topics: Adjuvants, Immunologic; Animals; COVID-19; COVID-19 Vaccines; Humans; Immunity; Mice; Mice, Inbred BALB C; Pandemics; Recombinant Proteins; Saccharomyces cerevisiae; SARS-CoV-2; Viral Vaccines

2022
Two formulations of coronavirus disease-19 recombinant subunit vaccine candidate made up of S1 fragment protein P1, S2 fragment protein P2, and nucleocapsid protein elicit strong immunogenicity in mice.
    Immunity, inflammation and disease, 2022, Volume: 10, Issue:12

    Topics: Aluminum Hydroxide; Animals; COVID-19; COVID-19 Vaccines; Humans; Mice; Nucleocapsid Proteins; Spike Glycoprotein, Coronavirus; Vaccines, Subunit

2022
SARS-CoV-2 delta (B.1.617.2) spike protein adjuvanted with Alum-3M-052 enhances antibody production and neutralization ability.
    Frontiers in public health, 2022, Volume: 10

    Topics: Animals; Antibody Formation; COVID-19; COVID-19 Vaccines; Female; Humans; Mice; SARS-CoV-2; Spike Glycoprotein, Coronavirus

2022
Enhancing neutralizing antibodies against receptor binding domain of SARS-CoV-2 by a safe natural adjuvant system.
    Virus research, 2023, Volume: 326

    Topics: Animals; Antibodies, Blocking; Antibodies, Neutralizing; Antibodies, Viral; COVID-19; Humans; Mammals; Mice; SARS-CoV-2; Spike Glycoprotein, Coronavirus

2023
Preclinical evaluation of immunogenicity, efficacy and safety of a recombinant plant-based SARS-CoV-2 RBD vaccine formulated with 3M-052-Alum adjuvant.
    Vaccine, 2023, 04-24, Volume: 41, Issue:17

    Topics: Adjuvants, Immunologic; Aluminum Hydroxide; Animals; Antibodies, Neutralizing; Antibodies, Viral; COVID-19; Immunogenicity, Vaccine; Macaca fascicularis; Mice; Rats; Rats, Sprague-Dawley; SARS-CoV-2; Spike Glycoprotein, Coronavirus

2023
Protection from COVID-19 disease in hamsters vaccinated with subunit SARS-CoV-2 S1 mucosal vaccines adjuvanted with different adjuvants.
    Frontiers in immunology, 2023, Volume: 14

    Topics: Adjuvants, Immunologic; Adjuvants, Pharmaceutic; Animals; COVID-19; COVID-19 Vaccines; Cricetinae; Female; Humans; Male; SARS-CoV-2; Vaccines, Subunit

2023
A ferritin-based COVID-19 nanoparticle vaccine that elicits robust, durable, broad-spectrum neutralizing antisera in non-human primates.
    Nature communications, 2023, 04-17, Volume: 14, Issue:1

    Topics: Animals; Antibodies, Neutralizing; Antibodies, Viral; COVID-19; COVID-19 Vaccines; Ferritins; Geranium; Humans; Immune Sera; Nanoparticles; Primates; SARS-CoV-2

2023
Recombinant Bacillus Calmette-Guérin Expressing SARS-CoV-2 Chimeric Protein Protects K18-hACE2 Mice against Viral Challenge.
    Journal of immunology (Baltimore, Md. : 1950), 2023, 06-15, Volume: 210, Issue:12

    Topics: Animals; BCG Vaccine; COVID-19; Mice; Mycobacterium bovis; Recombinant Fusion Proteins; SARS-CoV-2; Vaccines, Synthetic

2023
Broad and Durable Humoral Responses Following Single Hydrogel Immunization of SARS-CoV-2 Subunit Vaccine.
    Advanced healthcare materials, 2023, Volume: 12, Issue:28

    Topics: Antibodies, Viral; COVID-19; COVID-19 Vaccines; Humans; Hydrogels; Immunity, Humoral; Immunization; SARS-CoV-2; Vaccination; Vaccines, Subunit

2023
An intranasal vaccine comprising SARS-CoV-2 spike receptor-binding domain protein entrapped in mannose-conjugated chitosan nanoparticle provides protection in hamsters.
    Scientific reports, 2023, 07-26, Volume: 13, Issue:1

    Topics: Adjuvants, Immunologic; Aluminum Hydroxide; Animals; Antibodies, Neutralizing; Antibodies, Viral; Chitosan; COVID-19; COVID-19 Vaccines; Cricetinae; Mannose; Mesocricetus; Mice; Mice, Inbred BALB C; Nanoparticles; SARS-CoV-2; Spike Glycoprotein, Coronavirus; Vaccines

2023
Comparison of Immunogenicity of Alum and MF59-Like Adjuvant Inactivated SARS-CoV-2 Vaccines Against SARS-CoV-2 Variants in Elderly Mice.
    Viral immunology, 2023, Volume: 36, Issue:8

    Topics: Adjuvants, Immunologic; Aged; Animals; Antibodies, Neutralizing; Antibodies, Viral; COVID-19; COVID-19 Vaccines; Humans; Infant; Mice; SARS-CoV-2; Vaccines, Inactivated

2023
The immunogenicity of Alum+CpG adjuvant SARS-CoV-2 inactivated vaccine in mice.
    Vaccine, 2023, 09-22, Volume: 41, Issue:41

    Topics: Adjuvants, Immunologic; Aluminum Hydroxide; Animals; COVID-19; Mice; SARS-CoV-2

2023
Subunit vaccine raised against the SARS-CoV-2 spike of Delta and Omicron variants.
    Journal of medical virology, 2023, Volume: 95, Issue:10

    Topics: Animals; Antibodies, Neutralizing; Antibodies, Viral; COVID-19; Cricetinae; Mesocricetus; Mice; Mice, Inbred C57BL; Recombinant Proteins; SARS-CoV-2; Spike Glycoprotein, Coronavirus; Vaccines, Subunit

2023
Effects of aluminum-salt, CpG and emulsion adjuvants on the stability and immunogenicity of a virus-like particle displaying the SARS-CoV-2 receptor-binding domain (RBD).
    Human vaccines & immunotherapeutics, 2023, Volume: 19, Issue:2

    Topics: Adjuvants, Immunologic; Aluminum; Animals; Antibodies, Neutralizing; Antibodies, Viral; COVID-19; COVID-19 Vaccines; Emulsions; Humans; Mice; SARS-CoV-2; Spike Glycoprotein, Coronavirus; Vaccines, Synthetic; Vaccines, Virus-Like Particle

2023
SARS-CoV-2 S1 is superior to the RBD as a COVID-19 subunit vaccine antigen.
    Journal of medical virology, 2021, Volume: 93, Issue:2

    Topics: Adjuvants, Immunologic; Alum Compounds; Animals; Antibodies, Neutralizing; Antibodies, Viral; Antigens, Viral; COVID-19; COVID-19 Vaccines; Female; HEK293 Cells; Humans; Immunity, Humoral; Immunization; Immunization Schedule; Immunogenicity, Vaccine; Immunoglobulin A; Immunoglobulin G; Mice; Mice, Inbred BALB C; Protein Domains; Recombinant Proteins; SARS-CoV-2; Spike Glycoprotein, Coronavirus; Th1 Cells; Th2 Cells

2021
Particulate Alum via Pickering Emulsion for an Enhanced COVID-19 Vaccine Adjuvant.
    Advanced materials (Deerfield Beach, Fla.), 2020, Volume: 32, Issue:40

    Topics: Adjuvants, Immunologic; Alum Compounds; Animals; Antigens, Viral; Coronavirus Infections; COVID-19; COVID-19 Vaccines; Emulsions; HEK293 Cells; Humans; Interferon-gamma; Mice, Inbred BALB C; Pandemics; Pneumonia, Viral; Spike Glycoprotein, Coronavirus; T-Lymphocytes; Viral Vaccines

2020
Adjuvanting a subunit COVID-19 vaccine to induce protective immunity.
    Nature, 2021, Volume: 594, Issue:7862

    Topics: Adjuvants, Immunologic; Alum Compounds; Animals; Antibodies, Neutralizing; Antibodies, Viral; CD4-Positive T-Lymphocytes; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; COVID-19; COVID-19 Vaccines; Disease Models, Animal; Immunity, Cellular; Immunity, Humoral; Macaca mulatta; Male; Oligodeoxyribonucleotides; SARS-CoV-2; Spike Glycoprotein, Coronavirus; Squalene; Vaccines, Subunit

2021
SARS-CoV-2 RBD trimer protein adjuvanted with Alum-3M-052 protects from SARS-CoV-2 infection and immune pathology in the lung.
    Nature communications, 2021, 06-11, Volume: 12, Issue:1

    Topics: Adjuvants, Immunologic; Alum Compounds; Angiotensin-Converting Enzyme 2; Animals; Antibodies, Neutralizing; Antibodies, Viral; Antibody Formation; COVID-19; COVID-19 Vaccines; Disease Models, Animal; Heterocyclic Compounds, 3-Ring; Humans; Macaca mulatta; Mice; Protein Binding; SARS-CoV-2; Spike Glycoprotein, Coronavirus; Stearic Acids

2021
A yeast expressed RBD-based SARS-CoV-2 vaccine formulated with 3M-052-alum adjuvant promotes protective efficacy in non-human primates.
    Science immunology, 2021, 07-15, Volume: 6, Issue:61

    Topics: Adjuvants, Immunologic; Administration, Inhalation; Administration, Intranasal; Alum Compounds; Animals; Antibodies, Neutralizing; Antibodies, Viral; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Line; COVID-19; COVID-19 Vaccines; Cytokines; Humans; Immunoglobulin G; Lung; Macaca mulatta; Male; Protein Binding; Protein Domains; Saccharomycetales; SARS-CoV-2; Spike Glycoprotein, Coronavirus; Viral Load

2021
Inhibition of elastase enhances the adjuvanticity of alum and promotes anti-SARS-CoV-2 systemic and mucosal immunity.
    Proceedings of the National Academy of Sciences of the United States of America, 2021, 08-24, Volume: 118, Issue:34

    Topics: Adjuvants, Immunologic; Alum Compounds; Animals; Antibodies, Neutralizing; Antibodies, Viral; Antibody Formation; COVID-19; COVID-19 Drug Treatment; Enzyme Inhibitors; HEK293 Cells; Humans; Immunity, Innate; Immunity, Mucosal; Immunoglobulin A; Leukocyte Elastase; Mice; Mice, Inbred C57BL; Mice, Knockout; SARS-CoV-2; Spike Glycoprotein, Coronavirus; Swine; Th1 Cells

2021