Page last updated: 2024-10-22

altretamine and Plasmacytoma

altretamine has been researched along with Plasmacytoma in 4 studies

Altretamine: A hexamethyl-2,4,6-triamine derivative of 1,3,5-triazine.

Plasmacytoma: Any discrete, presumably solitary, mass of neoplastic PLASMA CELLS either in BONE MARROW or various extramedullary sites.

Research Excerpts

ExcerptRelevanceReference
" Pharmacokinetic studies in mouse, rat and man did not show the major species differences characteristic of PMM."1.27Preclinical toxicology, pharmacokinetics and formulation of N2,N4,N6-trihydroxymethyl-N2,N4,N6-trimethylmelamine (trimelamol), a water-soluble cytotoxic s-triazine which does not require metabolic activation. ( Abel, G; Goddard, PM; Harrap, KR; Judson, IR; Newell, DR; Rutty, CJ, 1986)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19904 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Morimoto, M1
Green, D1
Rahman, A1
Goldin, A1
Schein, PS1
Cumber, AJ1
Ross, WC1
Paolini, A1
D'Incalci, M1
Rutty, CJ1
Judson, IR1
Abel, G1
Goddard, PM1
Newell, DR1
Harrap, KR1

Other Studies

4 other studies available for altretamine and Plasmacytoma

ArticleYear
Comparative pharmacology of pentamethylmelamine and hexamethylmelamine in mice.
    Cancer research, 1980, Volume: 40, Issue:8 Pt 1

    Topics: Alkylating Agents; Altretamine; Animals; DNA Replication; DNA, Neoplasm; Leukocyte Count; Male; Mice

1980
Analogues of hexamethylmelamine. The anti-neoplastic activity of derivatives with enhanced water solubility.
    Chemico-biological interactions, 1977, Volume: 17, Issue:3

    Topics: Altretamine; Animals; Humans; Lung Neoplasms; Mice; Neoplasm Transplantation; Neoplasms, Experimenta

1977
Effect of phenobarbital pretreatment on the metabolism and antitumor activity of hexamethylmelamine.
    Cancer treatment reports, 1986, Volume: 70, Issue:4

    Topics: Altretamine; Animals; Cell Line; Chromatography, Gas; Drug Interactions; Female; Kinetics; Male; Mic

1986
Preclinical toxicology, pharmacokinetics and formulation of N2,N4,N6-trihydroxymethyl-N2,N4,N6-trimethylmelamine (trimelamol), a water-soluble cytotoxic s-triazine which does not require metabolic activation.
    Cancer chemotherapy and pharmacology, 1986, Volume: 17, Issue:3

    Topics: Altretamine; Animals; Antineoplastic Agents; Carcinoma 256, Walker; Chromatography, High Pressure Li

1986