altretamine has been researched along with Nausea in 18 studies
Altretamine: A hexamethyl-2,4,6-triamine derivative of 1,3,5-triazine.
Nausea: An unpleasant sensation in the stomach usually accompanied by the urge to vomit. Common causes are early pregnancy, sea and motion sickness, emotional stress, intense pain, food poisoning, and various enteroviruses.
Excerpt | Relevance | Reference |
---|---|---|
"A four-drug combination of intermittent high-dose cyclophosphamide with 5-fluorouracil, hexamethylmelamine, and prednisone was given to 19 patients with advanced breast cancer." | 7.66 | Phase I--II evaluation of combination cyclophosphamide, 5-fluorouracil, hexamethylmelamine, and prednisone in advanced breast cancer. ( Chang, YC; Crowley, J; Falkson, G; Tormey, DC, 1981) |
"A four-drug combination of intermittent high-dose cyclophosphamide with 5-fluorouracil, hexamethylmelamine, and prednisone was given to 19 patients with advanced breast cancer." | 3.66 | Phase I--II evaluation of combination cyclophosphamide, 5-fluorouracil, hexamethylmelamine, and prednisone in advanced breast cancer. ( Chang, YC; Crowley, J; Falkson, G; Tormey, DC, 1981) |
" Pharmacokinetic studies (100-500 mg m-2) indicated that PMM plasma levels are dose-dependent and that the PMM disposition-phase half-life is prolonged in patients with abnormal liver function." | 2.65 | Pentamethylmelamine (PMM): Phase I clinical and pharmacokinetic studies. ( Harrap, KR; Muindi, JR; Newell, DR; Smith, IE, 1983) |
"Ninety-eight patients with metastatic breast cancer, heavily pretreated with other agents, were entered in a phase II trial of hexamethylmelamine (HEX)." | 2.65 | Phase II evaluation of hexamethylmelamine in advanced breast cancer: a Southwest Oncology Group study. ( Balcerzak, S; Fabian, CJ; Haut, A; Rasmussen, S; Smith, F; Stephens, R; Tranum, B, 1979) |
"Eleven patients with metastatic breast cancer refractory to conventional therapy were treated with a combination of hexamethylmelamine 250 mg/m2 p." | 1.26 | An evaluation of hexamethylmelamine, cis-diamminedichloroplatinum, and mitomycin-C in advanced breast cancer. A pilot study of the Southeastern Cancer Study Group. ( Lawson, D; Moore, M; Smalley, R, 1980) |
"Pentamethylmelamine is a soluble monodemethylated derivative of hexamethylmelamine." | 1.26 | Phase I study of pentamethylmelamine. ( Goldberg, RS; Griffin, JP; Krakoff, IH; McSherry, JW, 1980) |
"Twenty-one patients with advanced ovarian cancer proven resistant to standard alkylating chemotherapy were evaluated in a prospective study of Hexamethylmelamine." | 1.26 | Hexamethylmelamine in alkylating agent-resistant ovarian carcinoma. ( Bender, RA; Chabner, BA; DeVita, VT; Fisher, RI; Johnson, BL; Young, RC, 1978) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 17 (94.44) | 18.7374 |
1990's | 1 (5.56) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Muindi, JR | 1 |
Newell, DR | 1 |
Smith, IE | 1 |
Harrap, KR | 1 |
Carmo-Pereira, J | 1 |
Costa, FO | 1 |
Henriques, E | 1 |
Gad-el-Mawla, N | 2 |
Ziegler, JL | 1 |
Hamza, R | 1 |
Elserafi, M | 1 |
Khaled, H | 2 |
Macdonald, JS | 1 |
Lawson, D | 1 |
Moore, M | 1 |
Smalley, R | 1 |
Freedman, RS | 1 |
Herson, J | 1 |
Wharton, JT | 1 |
Rutledge, FN | 1 |
Goldberg, RS | 1 |
Griffin, JP | 1 |
McSherry, JW | 1 |
Krakoff, IH | 1 |
Van Echo, DA | 1 |
Chiuten, DF | 1 |
Whitacre, M | 1 |
Aisner, J | 1 |
Lichtenfeld, JL | 1 |
Wiernik, PH | 1 |
Lopez, JA | 1 |
Krikorian, JG | 1 |
Dias, SF | 1 |
Spiers, AS | 1 |
Finkel, HE | 1 |
Barnard, DE | 1 |
Casper, ES | 1 |
Gralla, RJ | 1 |
Lynch, GR | 1 |
Jones, BR | 1 |
Woodcock, TM | 1 |
Gordon, C | 1 |
Kelsen, DP | 1 |
Young, CW | 1 |
Seski, JC | 1 |
Edwards, CL | 1 |
Copeland, LJ | 1 |
Gershenson, DM | 1 |
Chang, YC | 1 |
Falkson, G | 1 |
Tormey, DC | 1 |
Crowley, J | 1 |
Johnson, BL | 1 |
Fisher, RI | 1 |
Bender, RA | 1 |
DeVita, VT | 1 |
Chabner, BA | 1 |
Young, RC | 1 |
Fabian, CJ | 1 |
Rasmussen, S | 1 |
Stephens, R | 1 |
Haut, A | 1 |
Smith, F | 1 |
Balcerzak, S | 1 |
Tranum, B | 1 |
Wilson, WL | 1 |
Ryzin, JV | 1 |
Weiss, AJ | 1 |
Frelick, RW | 1 |
Moss, SE | 1 |
Denefrio, JM | 1 |
Vogel, CL | 1 |
Ames, MM | 1 |
Richardson, RL | 1 |
Kovach, JS | 1 |
Moertel, CG | 1 |
O'Connell, MJ | 1 |
Wilman, DE | 1 |
7 trials available for altretamine and Nausea
Article | Year |
---|---|
Pentamethylmelamine (PMM): Phase I clinical and pharmacokinetic studies.
Topics: Adult; Aged; Altretamine; Antineoplastic Agents; Clinical Trials as Topic; Female; Humans; Kinetics; | 1983 |
cis-Platinum, adriamycin, and hexamethylmelamine versus cyclophosphamide in advanced ovarian carcinoma.
Topics: Adult; Aged; Altretamine; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Femal | 1983 |
Randomized phase II trial of hexamethylmelamine versus pentamethylmelamine in carcinoma of the bilharzial bladder.
Topics: Altretamine; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Evaluation; Humans; Nausea; Rando | 1984 |
Single-agent chemotherapy for recurrent carcinoma of the cervix.
Topics: Altretamine; Anemia; Antineoplastic Agents; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; | 1980 |
Phase II evaluation of hexamethylmelamine in advanced breast cancer: a Southwest Oncology Group study.
Topics: Aged; Altretamine; Breast Neoplasms; Drug Evaluation; Female; Humans; Middle Aged; Nausea; Nervous S | 1979 |
A phase III study in lung carcinoma comparing hexamethyl-melamine (NSC 13875) to dibromodulcitol (NSC 104800) 1,2.
Topics: Adenocarcinoma; Altretamine; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Clinical Trials as Top | 1975 |
Phase I and clinical pharmacological evaluation of a parenteral hexamethylmelamine formulation.
Topics: Altretamine; Clinical Trials as Topic; Drug Administration Schedule; Drug Evaluation; Female; Humans | 1990 |
11 other studies available for altretamine and Nausea
Article | Year |
---|---|
Hexamethylmelamine in advanced head and neck cancer. A phase II study.
Topics: Aged; Altretamine; Carcinoma, Squamous Cell; Drug Evaluation; Egypt; Female; Head and Neck Neoplasms | 1984 |
An evaluation of hexamethylmelamine, cis-diamminedichloroplatinum, and mitomycin-C in advanced breast cancer. A pilot study of the Southeastern Cancer Study Group.
Topics: Altretamine; Breast Neoplasms; Cisplatin; Drug Evaluation; Drug Therapy, Combination; Female; Humans | 1980 |
Phase I study of pentamethylmelamine.
Topics: Adult; Altretamine; Dose-Response Relationship, Drug; Drug Evaluation; Electroencephalography; Human | 1980 |
Phase I trial of pentamethylmelamine in patients with previously treated malignancies.
Topics: Adult; Aged; Altretamine; Anorexia; Central Nervous System; Dose-Response Relationship, Drug; Drug A | 1980 |
cis-Platinum-hexamethylmelamine therapy of advanced ovarian cancer.
Topics: Adult; Altretamine; Cisplatin; Drug Therapy, Combination; Female; Humans; Middle Aged; Nausea; Ovari | 1981 |
Phase I and pharmacological studies of pentamethylmelamine administered by 24-hour intravenous infusion.
Topics: Adult; Aged; Altretamine; Antineoplastic Agents; Drug Administration Schedule; Drug Evaluation; Fema | 1981 |
Hexamethylmelamine chemotherapy for disseminated endometrial cancer.
Topics: Aged; Altretamine; Ataxia; Confusion; Female; Humans; Middle Aged; Muscle Hypotonia; Nausea; Reflex, | 1981 |
Phase I--II evaluation of combination cyclophosphamide, 5-fluorouracil, hexamethylmelamine, and prednisone in advanced breast cancer.
Topics: Adenocarcinoma; Adult; Aged; Altretamine; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; | 1981 |
Hexamethylmelamine in alkylating agent-resistant ovarian carcinoma.
Topics: Adenocarcinoma; Adult; Aged; Alkylating Agents; Altretamine; Bone Marrow; Drug Resistance; Female; H | 1978 |
Phae II study of hexamethylmelamine in women with advanced breast cancer refractory to standard cytotoxic therapy.
Topics: Alkylating Agents; Altretamine; Breast Neoplasms; Drug Evaluation; Drug Resistance; Female; Humans; | 1978 |
Prodrugs in cancer chemotherapy.
Topics: Altretamine; Aniline Mustard; Animals; Antineoplastic Agents; Azo Compounds; Biotransformation; Chem | 1986 |