altretamine has been researched along with Nausea in 18 studies
Altretamine: A hexamethyl-2,4,6-triamine derivative of 1,3,5-triazine.
Nausea: An unpleasant sensation in the stomach usually accompanied by the urge to vomit. Common causes are early pregnancy, sea and motion sickness, emotional stress, intense pain, food poisoning, and various enteroviruses.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A four-drug combination of intermittent high-dose cyclophosphamide with 5-fluorouracil, hexamethylmelamine, and prednisone was given to 19 patients with advanced breast cancer." | 7.66 | Phase I--II evaluation of combination cyclophosphamide, 5-fluorouracil, hexamethylmelamine, and prednisone in advanced breast cancer. ( Chang, YC; Crowley, J; Falkson, G; Tormey, DC, 1981) |
| "A four-drug combination of intermittent high-dose cyclophosphamide with 5-fluorouracil, hexamethylmelamine, and prednisone was given to 19 patients with advanced breast cancer." | 3.66 | Phase I--II evaluation of combination cyclophosphamide, 5-fluorouracil, hexamethylmelamine, and prednisone in advanced breast cancer. ( Chang, YC; Crowley, J; Falkson, G; Tormey, DC, 1981) |
| " Pharmacokinetic studies (100-500 mg m-2) indicated that PMM plasma levels are dose-dependent and that the PMM disposition-phase half-life is prolonged in patients with abnormal liver function." | 2.65 | Pentamethylmelamine (PMM): Phase I clinical and pharmacokinetic studies. ( Harrap, KR; Muindi, JR; Newell, DR; Smith, IE, 1983) |
| "Ninety-eight patients with metastatic breast cancer, heavily pretreated with other agents, were entered in a phase II trial of hexamethylmelamine (HEX)." | 2.65 | Phase II evaluation of hexamethylmelamine in advanced breast cancer: a Southwest Oncology Group study. ( Balcerzak, S; Fabian, CJ; Haut, A; Rasmussen, S; Smith, F; Stephens, R; Tranum, B, 1979) |
| "Eleven patients with metastatic breast cancer refractory to conventional therapy were treated with a combination of hexamethylmelamine 250 mg/m2 p." | 1.26 | An evaluation of hexamethylmelamine, cis-diamminedichloroplatinum, and mitomycin-C in advanced breast cancer. A pilot study of the Southeastern Cancer Study Group. ( Lawson, D; Moore, M; Smalley, R, 1980) |
| "Pentamethylmelamine is a soluble monodemethylated derivative of hexamethylmelamine." | 1.26 | Phase I study of pentamethylmelamine. ( Goldberg, RS; Griffin, JP; Krakoff, IH; McSherry, JW, 1980) |
| "Twenty-one patients with advanced ovarian cancer proven resistant to standard alkylating chemotherapy were evaluated in a prospective study of Hexamethylmelamine." | 1.26 | Hexamethylmelamine in alkylating agent-resistant ovarian carcinoma. ( Bender, RA; Chabner, BA; DeVita, VT; Fisher, RI; Johnson, BL; Young, RC, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (94.44) | 18.7374 |
| 1990's | 1 (5.56) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Muindi, JR | 1 |
| Newell, DR | 1 |
| Smith, IE | 1 |
| Harrap, KR | 1 |
| Carmo-Pereira, J | 1 |
| Costa, FO | 1 |
| Henriques, E | 1 |
| Gad-el-Mawla, N | 2 |
| Ziegler, JL | 1 |
| Hamza, R | 1 |
| Elserafi, M | 1 |
| Khaled, H | 2 |
| Macdonald, JS | 1 |
| Lawson, D | 1 |
| Moore, M | 1 |
| Smalley, R | 1 |
| Freedman, RS | 1 |
| Herson, J | 1 |
| Wharton, JT | 1 |
| Rutledge, FN | 1 |
| Goldberg, RS | 1 |
| Griffin, JP | 1 |
| McSherry, JW | 1 |
| Krakoff, IH | 1 |
| Van Echo, DA | 1 |
| Chiuten, DF | 1 |
| Whitacre, M | 1 |
| Aisner, J | 1 |
| Lichtenfeld, JL | 1 |
| Wiernik, PH | 1 |
| Lopez, JA | 1 |
| Krikorian, JG | 1 |
| Dias, SF | 1 |
| Spiers, AS | 1 |
| Finkel, HE | 1 |
| Barnard, DE | 1 |
| Casper, ES | 1 |
| Gralla, RJ | 1 |
| Lynch, GR | 1 |
| Jones, BR | 1 |
| Woodcock, TM | 1 |
| Gordon, C | 1 |
| Kelsen, DP | 1 |
| Young, CW | 1 |
| Seski, JC | 1 |
| Edwards, CL | 1 |
| Copeland, LJ | 1 |
| Gershenson, DM | 1 |
| Chang, YC | 1 |
| Falkson, G | 1 |
| Tormey, DC | 1 |
| Crowley, J | 1 |
| Johnson, BL | 1 |
| Fisher, RI | 1 |
| Bender, RA | 1 |
| DeVita, VT | 1 |
| Chabner, BA | 1 |
| Young, RC | 1 |
| Fabian, CJ | 1 |
| Rasmussen, S | 1 |
| Stephens, R | 1 |
| Haut, A | 1 |
| Smith, F | 1 |
| Balcerzak, S | 1 |
| Tranum, B | 1 |
| Wilson, WL | 1 |
| Ryzin, JV | 1 |
| Weiss, AJ | 1 |
| Frelick, RW | 1 |
| Moss, SE | 1 |
| Denefrio, JM | 1 |
| Vogel, CL | 1 |
| Ames, MM | 1 |
| Richardson, RL | 1 |
| Kovach, JS | 1 |
| Moertel, CG | 1 |
| O'Connell, MJ | 1 |
| Wilman, DE | 1 |
7 trials available for altretamine and Nausea
| Article | Year |
|---|---|
Pentamethylmelamine (PMM): Phase I clinical and pharmacokinetic studies.
Topics: Adult; Aged; Altretamine; Antineoplastic Agents; Clinical Trials as Topic; Female; Humans; Kinetics; | 1983 |
cis-Platinum, adriamycin, and hexamethylmelamine versus cyclophosphamide in advanced ovarian carcinoma.
Topics: Adult; Aged; Altretamine; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Femal | 1983 |
Randomized phase II trial of hexamethylmelamine versus pentamethylmelamine in carcinoma of the bilharzial bladder.
Topics: Altretamine; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Evaluation; Humans; Nausea; Rando | 1984 |
Single-agent chemotherapy for recurrent carcinoma of the cervix.
Topics: Altretamine; Anemia; Antineoplastic Agents; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; | 1980 |
Phase II evaluation of hexamethylmelamine in advanced breast cancer: a Southwest Oncology Group study.
Topics: Aged; Altretamine; Breast Neoplasms; Drug Evaluation; Female; Humans; Middle Aged; Nausea; Nervous S | 1979 |
A phase III study in lung carcinoma comparing hexamethyl-melamine (NSC 13875) to dibromodulcitol (NSC 104800) 1,2.
Topics: Adenocarcinoma; Altretamine; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Clinical Trials as Top | 1975 |
Phase I and clinical pharmacological evaluation of a parenteral hexamethylmelamine formulation.
Topics: Altretamine; Clinical Trials as Topic; Drug Administration Schedule; Drug Evaluation; Female; Humans | 1990 |
11 other studies available for altretamine and Nausea
| Article | Year |
|---|---|
Hexamethylmelamine in advanced head and neck cancer. A phase II study.
Topics: Aged; Altretamine; Carcinoma, Squamous Cell; Drug Evaluation; Egypt; Female; Head and Neck Neoplasms | 1984 |
An evaluation of hexamethylmelamine, cis-diamminedichloroplatinum, and mitomycin-C in advanced breast cancer. A pilot study of the Southeastern Cancer Study Group.
Topics: Altretamine; Breast Neoplasms; Cisplatin; Drug Evaluation; Drug Therapy, Combination; Female; Humans | 1980 |
Phase I study of pentamethylmelamine.
Topics: Adult; Altretamine; Dose-Response Relationship, Drug; Drug Evaluation; Electroencephalography; Human | 1980 |
Phase I trial of pentamethylmelamine in patients with previously treated malignancies.
Topics: Adult; Aged; Altretamine; Anorexia; Central Nervous System; Dose-Response Relationship, Drug; Drug A | 1980 |
cis-Platinum-hexamethylmelamine therapy of advanced ovarian cancer.
Topics: Adult; Altretamine; Cisplatin; Drug Therapy, Combination; Female; Humans; Middle Aged; Nausea; Ovari | 1981 |
Phase I and pharmacological studies of pentamethylmelamine administered by 24-hour intravenous infusion.
Topics: Adult; Aged; Altretamine; Antineoplastic Agents; Drug Administration Schedule; Drug Evaluation; Fema | 1981 |
Hexamethylmelamine chemotherapy for disseminated endometrial cancer.
Topics: Aged; Altretamine; Ataxia; Confusion; Female; Humans; Middle Aged; Muscle Hypotonia; Nausea; Reflex, | 1981 |
Phase I--II evaluation of combination cyclophosphamide, 5-fluorouracil, hexamethylmelamine, and prednisone in advanced breast cancer.
Topics: Adenocarcinoma; Adult; Aged; Altretamine; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; | 1981 |
Hexamethylmelamine in alkylating agent-resistant ovarian carcinoma.
Topics: Adenocarcinoma; Adult; Aged; Alkylating Agents; Altretamine; Bone Marrow; Drug Resistance; Female; H | 1978 |
Phae II study of hexamethylmelamine in women with advanced breast cancer refractory to standard cytotoxic therapy.
Topics: Alkylating Agents; Altretamine; Breast Neoplasms; Drug Evaluation; Drug Resistance; Female; Humans; | 1978 |
Prodrugs in cancer chemotherapy.
Topics: Altretamine; Aniline Mustard; Animals; Antineoplastic Agents; Azo Compounds; Biotransformation; Chem | 1986 |