altretamine has been researched along with Metastase in 21 studies
Altretamine: A hexamethyl-2,4,6-triamine derivative of 1,3,5-triazine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hexamethylmelamine, mitomycin C and 5-fluorouracil infusion (HexMF) achieved a median survival of 9 months for the 45 patients with either metastatic stage III or unresectable stage II carcinoma of the pancreas." | 3.67 | Primary treatment of regional and disseminated pancreatic cancer with hexamethylmelamine, mitomycin C and 5-fluorouracil infusion. ( Bruckner, HW; Butwell, N; Gorbaty, MI; Kalman, J; McKenna, A; Spigelman, M; Storch, J, 1989) |
| " Fifteen patients with sarcoma metastases in the soft tissue were treated with karminomycin in combnation with methotrexate and cyclophosphane." | 3.65 | [Carminomycin in drug combination in breast cancer and soft tissue sarcomas]. ( Assekritova, IV; Gorbunova, VA; Lichinitser, MR, 1977) |
| "The age adjusted death rate for ovarian cancer has remained unchanged for the past 20 years." | 2.64 | Advances in the staging and treatment of ovarian cancer. ( Fisher, RI; Young, RC, 1977) |
| "Twenty-three patients with metastatic breast carcinoma were induced with a complex systemic therapy regimen in an attempt to ascertain if a complete remission rate greater than 50% could be obtained with intensive drug exposure." | 1.27 | Short term high density systemic therapy for metastatic breast cancer. ( Carbone, PP; Davis, TE; Kline, JC; Love, RR; Palta, M; Tormey, DC, 1985) |
| "Eleven patients with metastatic breast cancer refractory to conventional therapy were treated with a combination of hexamethylmelamine 250 mg/m2 p." | 1.26 | An evaluation of hexamethylmelamine, cis-diamminedichloroplatinum, and mitomycin-C in advanced breast cancer. A pilot study of the Southeastern Cancer Study Group. ( Lawson, D; Moore, M; Smalley, R, 1980) |
| "HMM concentrations in metastases appeared to be higher than in the primary tumor, and in metastases with a diameter less than 3 mm, drug levels were two to ten times those in larger ones." | 1.26 | Hexamethylmelamine distribution in patients with ovarian and other pelvic cancers. ( D'Incalci, M; Farina, P; Garattini, S; Mangioni, C; Sessa, C, 1982) |
| "Thirteen cases of acute nonlymphocytic leukemia occurred among 5455 patients, as compared to 0." | 1.26 | Acute leukemia after alkylating-agent therapy of ovarian cancer. ( Fraumeni, JF; Hoover, R; Reimer, RR; Young, RC, 1977) |
| "Clinical chemotherapy in the treatment of neuroblastoma is undergoing further evaluation." | 1.26 | Studies and characterization of a murine neuroblastoma model. ( Chu, TM; Keogh, B; Moore, RH; Murphy, GP; Williams, P, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (95.24) | 18.7374 |
| 1990's | 1 (4.76) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chahinian, AP | 1 |
| Green, G | 1 |
| Holland, JF | 1 |
| Lawson, D | 1 |
| Moore, M | 1 |
| Smalley, R | 1 |
| Drelichman, A | 1 |
| Brownlee, R | 1 |
| Al-Sarraf, M | 1 |
| D'Incalci, M | 1 |
| Farina, P | 1 |
| Sessa, C | 1 |
| Mangioni, C | 1 |
| Garattini, S | 1 |
| Lichinitser, MR | 2 |
| Perevodchikova, NI | 1 |
| Garin, AM | 1 |
| Asserkritova, IV | 1 |
| Vaarik, GKh | 1 |
| Van Amburg, AL | 1 |
| Presant, CA | 1 |
| Vélez-García, E | 1 |
| Klahr, C | 1 |
| Krauss, S | 1 |
| Tornyos, K | 1 |
| DeSimone, P | 1 |
| Lowenbraun, S | 1 |
| McKeown, J | 1 |
| Solomon, A | 1 |
| Sonoda, T | 1 |
| Fisher, RI | 1 |
| Young, RC | 2 |
| Reimer, RR | 1 |
| Hoover, R | 1 |
| Fraumeni, JF | 1 |
| Assekritova, IV | 1 |
| Gorbunova, VA | 1 |
| Borden, EC | 1 |
| Larson, P | 1 |
| Ansfield, FJ | 1 |
| Bryan, GT | 1 |
| Johnson, RO | 1 |
| Ramirez, G | 1 |
| Wilson, WL | 2 |
| Denefrio, JM | 1 |
| Vogel, CL | 1 |
| Holoye, PY | 1 |
| Andrews, NC | 1 |
| Frelick, RW | 1 |
| Nealon, TF | 1 |
| Bick, RL | 1 |
| Adams, T | 1 |
| Keogh, B | 1 |
| Chu, TM | 1 |
| Williams, P | 1 |
| Moore, RH | 1 |
| Murphy, GP | 1 |
| Henderson, IC | 1 |
| Shapiro, CL | 1 |
| Tormey, DC | 1 |
| Kline, JC | 1 |
| Palta, M | 1 |
| Davis, TE | 1 |
| Love, RR | 1 |
| Carbone, PP | 1 |
| Patsner, B | 1 |
| Piver, MS | 1 |
| Lele, SB | 1 |
| Tsukada, Y | 1 |
| Bielat, K | 1 |
| Castillo, NB | 1 |
| Bruckner, HW | 1 |
| Kalman, J | 1 |
| Spigelman, M | 1 |
| Gorbaty, MI | 1 |
| Butwell, N | 1 |
| Storch, J | 1 |
| McKenna, A | 1 |
| Jacobs, RH | 1 |
| Greenburg, A | 1 |
| Bitran, JD | 1 |
| Hoffman, PC | 1 |
| Albain, KS | 1 |
| Desser, R | 1 |
| Potkul, L | 1 |
| Golomb, HM | 1 |
| Bonomi, PD | 1 |
| Pazdur, R | 1 |
| Stolbach, L | 1 |
| Mason, B | 1 |
| Ettinger, D | 1 |
1 review available for altretamine and Metastase
| Article | Year |
|---|---|
Hexamethylmelamine use in the treatment of metastatic breast cancer.
Topics: Altretamine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms | 1991 |
5 trials available for altretamine and Metastase
| Article | Year |
|---|---|
Mitomycin-C, etoposide, cisplatin, and hexamethylmelamine (MEPH) as a second-line regimen in lung cancer.
Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic; Cy | 1984 |
Phase I--II study of hexamethylmelamine plus dibromodulcitol in refractory carcinoma of the breast.
Topics: Adult; Aged; Altretamine; Breast Neoplasms; Clinical Trials as Topic; Drug Evaluation; Drug Therapy, | 1979 |
cis-Dichlorodiammineplatinum(II) and hexamethylmelamine in the treatment of non-oat cell lung cancer: a pilot study of the Southeastern Cancer Study Group.
Topics: Adenocarcinoma; Adult; Aged; Altretamine; Carcinoma; Carcinoma, Squamous Cell; Cisplatin; Clinical T | 1979 |
Advances in the staging and treatment of ovarian cancer.
Topics: Alkylating Agents; Altretamine; Antimetabolites, Antineoplastic; Clinical Trials as Topic; Cyclophos | 1977 |
Preliminary report on the use of CCNU (NSC-79037), adriamycin (NSC-123127), and hexamethylmelamine (NSC-13875) in carcinoma of the lung.
Topics: Adult; Aged; Altretamine; Carcinoma, Squamous Cell; Clinical Trials as Topic; Doxorubicin; Drug Eval | 1976 |
15 other studies available for altretamine and Metastase
| Article | Year |
|---|---|
An evaluation of hexamethylmelamine, cis-diamminedichloroplatinum, and mitomycin-C in advanced breast cancer. A pilot study of the Southeastern Cancer Study Group.
Topics: Altretamine; Breast Neoplasms; Cisplatin; Drug Evaluation; Drug Therapy, Combination; Female; Humans | 1980 |
Phase II study of hexamethylmelamine for disseminated prostatic carcinoma.
Topics: Aged; Altretamine; Drug Evaluation; Humans; Male; Middle Aged; Neoplasm Metastasis; Prostatic Neopla | 1981 |
Hexamethylmelamine distribution in patients with ovarian and other pelvic cancers.
Topics: Adipose Tissue; Adult; Aged; Altretamine; Chromatography, Gas; Female; Humans; Kinetics; Middle Aged | 1982 |
[Effectiveness of ftorafur and hexamethylmelamine in advanced breast cancer].
Topics: Adult; Altretamine; Breast Neoplasms; Drug Therapy, Combination; Female; Fluorouracil; Humans; Leuko | 1978 |
Acute leukemia after alkylating-agent therapy of ovarian cancer.
Topics: Acute Disease; Alkylating Agents; Altretamine; Chlorambucil; Cyclophosphamide; Female; Fluorouracil; | 1977 |
[Carminomycin in drug combination in breast cancer and soft tissue sarcomas].
Topics: Aged; Altretamine; Antibiotics, Antineoplastic; Breast Neoplasms; Carubicin; Cyclophosphamide; Drug | 1977 |
Hexamethylmelamine treatment of sarcomas and lymphomas.
Topics: Adolescent; Adult; Altretamine; Bone Marrow; Bone Neoplasms; Child; Digestive System; Female; Hodgki | 1977 |
Phae II study of hexamethylmelamine in women with advanced breast cancer refractory to standard cytotoxic therapy.
Topics: Alkylating Agents; Altretamine; Breast Neoplasms; Drug Evaluation; Drug Resistance; Female; Humans; | 1978 |
Management of small-cell bronchogenic carcinoma.
Topics: Altretamine; Antibiotics, Antineoplastic; Brain Neoplasms; Carcinoma, Bronchogenic; Cyclophosphamide | 1978 |
Studies and characterization of a murine neuroblastoma model.
Topics: Altretamine; Animals; Antigens, Neoplasm; Antineoplastic Agents; Cyclophosphamide; Disease Models, A | 1976 |
Short term high density systemic therapy for metastatic breast cancer.
Topics: Altretamine; Antineoplastic Agents; Bleomycin; Breast Neoplasms; Combined Modality Therapy; Doxorubi | 1985 |
Small cell carcinoma of the ovary: a rapidly lethal tumor occurring in the young.
Topics: Adolescent; Altretamine; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Small | 1985 |
Primary treatment of regional and disseminated pancreatic cancer with hexamethylmelamine, mitomycin C and 5-fluorouracil infusion.
Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Fluorouracil; Humans; Infusi | 1989 |
A 10-year experience with combined modality therapy for stage III small cell lung carcinoma.
Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modalit | 1986 |
Phase II trial of mitomycin, vindesine, and hexamethylmelamine in metastatic non-small cell bronchogenic carcinoma.
Topics: Adult; Aged; Altretamine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Bronchogenic; C | 1986 |