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altretamine and Metastase

altretamine has been researched along with Metastase in 21 studies

Altretamine: A hexamethyl-2,4,6-triamine derivative of 1,3,5-triazine.

Research Excerpts

ExcerptRelevanceReference
"Hexamethylmelamine, mitomycin C and 5-fluorouracil infusion (HexMF) achieved a median survival of 9 months for the 45 patients with either metastatic stage III or unresectable stage II carcinoma of the pancreas."3.67Primary treatment of regional and disseminated pancreatic cancer with hexamethylmelamine, mitomycin C and 5-fluorouracil infusion. ( Bruckner, HW; Butwell, N; Gorbaty, MI; Kalman, J; McKenna, A; Spigelman, M; Storch, J, 1989)
" Fifteen patients with sarcoma metastases in the soft tissue were treated with karminomycin in combnation with methotrexate and cyclophosphane."3.65[Carminomycin in drug combination in breast cancer and soft tissue sarcomas]. ( Assekritova, IV; Gorbunova, VA; Lichinitser, MR, 1977)
"The age adjusted death rate for ovarian cancer has remained unchanged for the past 20 years."2.64Advances in the staging and treatment of ovarian cancer. ( Fisher, RI; Young, RC, 1977)
"Twenty-three patients with metastatic breast carcinoma were induced with a complex systemic therapy regimen in an attempt to ascertain if a complete remission rate greater than 50% could be obtained with intensive drug exposure."1.27Short term high density systemic therapy for metastatic breast cancer. ( Carbone, PP; Davis, TE; Kline, JC; Love, RR; Palta, M; Tormey, DC, 1985)
"Eleven patients with metastatic breast cancer refractory to conventional therapy were treated with a combination of hexamethylmelamine 250 mg/m2 p."1.26An evaluation of hexamethylmelamine, cis-diamminedichloroplatinum, and mitomycin-C in advanced breast cancer. A pilot study of the Southeastern Cancer Study Group. ( Lawson, D; Moore, M; Smalley, R, 1980)
"HMM concentrations in metastases appeared to be higher than in the primary tumor, and in metastases with a diameter less than 3 mm, drug levels were two to ten times those in larger ones."1.26Hexamethylmelamine distribution in patients with ovarian and other pelvic cancers. ( D'Incalci, M; Farina, P; Garattini, S; Mangioni, C; Sessa, C, 1982)
"Thirteen cases of acute nonlymphocytic leukemia occurred among 5455 patients, as compared to 0."1.26Acute leukemia after alkylating-agent therapy of ovarian cancer. ( Fraumeni, JF; Hoover, R; Reimer, RR; Young, RC, 1977)
"Clinical chemotherapy in the treatment of neuroblastoma is undergoing further evaluation."1.26Studies and characterization of a murine neuroblastoma model. ( Chu, TM; Keogh, B; Moore, RH; Murphy, GP; Williams, P, 1976)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199020 (95.24)18.7374
1990's1 (4.76)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chahinian, AP1
Green, G1
Holland, JF1
Lawson, D1
Moore, M1
Smalley, R1
Drelichman, A1
Brownlee, R1
Al-Sarraf, M1
D'Incalci, M1
Farina, P1
Sessa, C1
Mangioni, C1
Garattini, S1
Lichinitser, MR2
Perevodchikova, NI1
Garin, AM1
Asserkritova, IV1
Vaarik, GKh1
Van Amburg, AL1
Presant, CA1
Vélez-García, E1
Klahr, C1
Krauss, S1
Tornyos, K1
DeSimone, P1
Lowenbraun, S1
McKeown, J1
Solomon, A1
Sonoda, T1
Fisher, RI1
Young, RC2
Reimer, RR1
Hoover, R1
Fraumeni, JF1
Assekritova, IV1
Gorbunova, VA1
Borden, EC1
Larson, P1
Ansfield, FJ1
Bryan, GT1
Johnson, RO1
Ramirez, G1
Wilson, WL2
Denefrio, JM1
Vogel, CL1
Holoye, PY1
Andrews, NC1
Frelick, RW1
Nealon, TF1
Bick, RL1
Adams, T1
Keogh, B1
Chu, TM1
Williams, P1
Moore, RH1
Murphy, GP1
Henderson, IC1
Shapiro, CL1
Tormey, DC1
Kline, JC1
Palta, M1
Davis, TE1
Love, RR1
Carbone, PP1
Patsner, B1
Piver, MS1
Lele, SB1
Tsukada, Y1
Bielat, K1
Castillo, NB1
Bruckner, HW1
Kalman, J1
Spigelman, M1
Gorbaty, MI1
Butwell, N1
Storch, J1
McKenna, A1
Jacobs, RH1
Greenburg, A1
Bitran, JD1
Hoffman, PC1
Albain, KS1
Desser, R1
Potkul, L1
Golomb, HM1
Bonomi, PD1
Pazdur, R1
Stolbach, L1
Mason, B1
Ettinger, D1

Reviews

1 review available for altretamine and Metastase

ArticleYear
Hexamethylmelamine use in the treatment of metastatic breast cancer.
    Cancer treatment reviews, 1991, Volume: 18 Suppl A

    Topics: Altretamine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms

1991

Trials

5 trials available for altretamine and Metastase

ArticleYear
Mitomycin-C, etoposide, cisplatin, and hexamethylmelamine (MEPH) as a second-line regimen in lung cancer.
    American journal of clinical oncology, 1984, Volume: 7, Issue:5

    Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic; Cy

1984
Phase I--II study of hexamethylmelamine plus dibromodulcitol in refractory carcinoma of the breast.
    Cancer treatment reports, 1979, Volume: 63, Issue:1

    Topics: Adult; Aged; Altretamine; Breast Neoplasms; Clinical Trials as Topic; Drug Evaluation; Drug Therapy,

1979
cis-Dichlorodiammineplatinum(II) and hexamethylmelamine in the treatment of non-oat cell lung cancer: a pilot study of the Southeastern Cancer Study Group.
    Cancer treatment reports, 1979, Volume: 63, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Altretamine; Carcinoma; Carcinoma, Squamous Cell; Cisplatin; Clinical T

1979
Advances in the staging and treatment of ovarian cancer.
    Cancer, 1977, Volume: 39, Issue:2 Suppl

    Topics: Alkylating Agents; Altretamine; Antimetabolites, Antineoplastic; Clinical Trials as Topic; Cyclophos

1977
Preliminary report on the use of CCNU (NSC-79037), adriamycin (NSC-123127), and hexamethylmelamine (NSC-13875) in carcinoma of the lung.
    Cancer treatment reports, 1976, Volume: 60, Issue:3

    Topics: Adult; Aged; Altretamine; Carcinoma, Squamous Cell; Clinical Trials as Topic; Doxorubicin; Drug Eval

1976

Other Studies

15 other studies available for altretamine and Metastase

ArticleYear
An evaluation of hexamethylmelamine, cis-diamminedichloroplatinum, and mitomycin-C in advanced breast cancer. A pilot study of the Southeastern Cancer Study Group.
    Cancer clinical trials, 1980, Volume: 3, Issue:4

    Topics: Altretamine; Breast Neoplasms; Cisplatin; Drug Evaluation; Drug Therapy, Combination; Female; Humans

1980
Phase II study of hexamethylmelamine for disseminated prostatic carcinoma.
    Cancer clinical trials, 1981,Fall, Volume: 4, Issue:3

    Topics: Aged; Altretamine; Drug Evaluation; Humans; Male; Middle Aged; Neoplasm Metastasis; Prostatic Neopla

1981
Hexamethylmelamine distribution in patients with ovarian and other pelvic cancers.
    Cancer treatment reports, 1982, Volume: 66, Issue:2

    Topics: Adipose Tissue; Adult; Aged; Altretamine; Chromatography, Gas; Female; Humans; Kinetics; Middle Aged

1982
[Effectiveness of ftorafur and hexamethylmelamine in advanced breast cancer].
    Voprosy onkologii, 1978, Volume: 24, Issue:8

    Topics: Adult; Altretamine; Breast Neoplasms; Drug Therapy, Combination; Female; Fluorouracil; Humans; Leuko

1978
Acute leukemia after alkylating-agent therapy of ovarian cancer.
    The New England journal of medicine, 1977, Jul-28, Volume: 297, Issue:4

    Topics: Acute Disease; Alkylating Agents; Altretamine; Chlorambucil; Cyclophosphamide; Female; Fluorouracil;

1977
[Carminomycin in drug combination in breast cancer and soft tissue sarcomas].
    Antibiotiki, 1977, Volume: 22, Issue:10

    Topics: Aged; Altretamine; Antibiotics, Antineoplastic; Breast Neoplasms; Carubicin; Cyclophosphamide; Drug

1977
Hexamethylmelamine treatment of sarcomas and lymphomas.
    Medical and pediatric oncology, 1977, Volume: 3, Issue:4

    Topics: Adolescent; Adult; Altretamine; Bone Marrow; Bone Neoplasms; Child; Digestive System; Female; Hodgki

1977
Phae II study of hexamethylmelamine in women with advanced breast cancer refractory to standard cytotoxic therapy.
    Cancer treatment reports, 1978, Volume: 62, Issue:1

    Topics: Alkylating Agents; Altretamine; Breast Neoplasms; Drug Evaluation; Drug Resistance; Female; Humans;

1978
Management of small-cell bronchogenic carcinoma.
    Comprehensive therapy, 1978, Volume: 4, Issue:2

    Topics: Altretamine; Antibiotics, Antineoplastic; Brain Neoplasms; Carcinoma, Bronchogenic; Cyclophosphamide

1978
Studies and characterization of a murine neuroblastoma model.
    Journal of surgical oncology, 1976, Volume: 8, Issue:6

    Topics: Altretamine; Animals; Antigens, Neoplasm; Antineoplastic Agents; Cyclophosphamide; Disease Models, A

1976
Short term high density systemic therapy for metastatic breast cancer.
    Breast cancer research and treatment, 1985, Volume: 5, Issue:2

    Topics: Altretamine; Antineoplastic Agents; Bleomycin; Breast Neoplasms; Combined Modality Therapy; Doxorubi

1985
Small cell carcinoma of the ovary: a rapidly lethal tumor occurring in the young.
    Gynecologic oncology, 1985, Volume: 22, Issue:2

    Topics: Adolescent; Altretamine; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Small

1985
Primary treatment of regional and disseminated pancreatic cancer with hexamethylmelamine, mitomycin C and 5-fluorouracil infusion.
    Oncology, 1989, Volume: 46, Issue:6

    Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Fluorouracil; Humans; Infusi

1989
A 10-year experience with combined modality therapy for stage III small cell lung carcinoma.
    Cancer, 1986, Nov-15, Volume: 58, Issue:10

    Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modalit

1986
Phase II trial of mitomycin, vindesine, and hexamethylmelamine in metastatic non-small cell bronchogenic carcinoma.
    Cancer treatment reports, 1986, Volume: 70, Issue:12

    Topics: Adult; Aged; Altretamine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Bronchogenic; C

1986