altretamine has been researched along with Leukopenia in 14 studies
Altretamine: A hexamethyl-2,4,6-triamine derivative of 1,3,5-triazine.
Leukopenia: A decrease in the number of LEUKOCYTES in a blood sample below the normal range (LEUKOCYTE COUNT less than 4000).
| Excerpt | Relevance | Reference |
|---|---|---|
| "A four-drug combination of intermittent high-dose cyclophosphamide with 5-fluorouracil, hexamethylmelamine, and prednisone was given to 19 patients with advanced breast cancer." | 7.66 | Phase I--II evaluation of combination cyclophosphamide, 5-fluorouracil, hexamethylmelamine, and prednisone in advanced breast cancer. ( Chang, YC; Crowley, J; Falkson, G; Tormey, DC, 1981) |
| "A four-drug combination of intermittent high-dose cyclophosphamide with 5-fluorouracil, hexamethylmelamine, and prednisone was given to 19 patients with advanced breast cancer." | 3.66 | Phase I--II evaluation of combination cyclophosphamide, 5-fluorouracil, hexamethylmelamine, and prednisone in advanced breast cancer. ( Chang, YC; Crowley, J; Falkson, G; Tormey, DC, 1981) |
| "Leukopenia was the dose-limiting toxicity." | 2.70 | Phase II study of vinorelbine in the treatment of platinum-resistant ovarian carcinoma. ( Bertelsen, K; Havsteen, H; Høyer, M; Jakobsen, A; Malmström, H; Sørensen, P, 2001) |
| "Thirty-eight women with advanced ovarian cancer were given monthly cycles of intravenous cyclophosphamide, Adriamycin (doxorubicin) and cis-platin, and oral hexamethylmelamine." | 1.27 | Cis-platin based combination chemotherapy for advanced ovarian cancer. High overall response rate with curative potential only in women with small tumor burdens. ( Arseneau, J; Bennett, B; Greenwald, E; Kaplan, BH; Pagano, M; Vogl, SE, 1983) |
| "Twenty-three patients with metastatic breast carcinoma were induced with a complex systemic therapy regimen in an attempt to ascertain if a complete remission rate greater than 50% could be obtained with intensive drug exposure." | 1.27 | Short term high density systemic therapy for metastatic breast cancer. ( Carbone, PP; Davis, TE; Kline, JC; Love, RR; Palta, M; Tormey, DC, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (92.86) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goldsweig, HG | 1 |
| Edgerton, F | 1 |
| Redden, CS | 1 |
| Takita, H | 1 |
| Garza, JG | 1 |
| Bisel, HF | 1 |
| Bruckner, HW | 1 |
| Cohen, CJ | 1 |
| Goldberg, JD | 1 |
| Kabakow, B | 1 |
| Wallach, RC | 1 |
| Deppe, G | 1 |
| Reisman, AZ | 1 |
| Gusberg, SB | 1 |
| Holland, JF | 2 |
| Carmo-Pereira, J | 1 |
| Costa, FO | 1 |
| Henriques, E | 1 |
| Edwards, CL | 1 |
| Herson, J | 1 |
| Gershenson, DM | 1 |
| Copeland, LJ | 1 |
| Wharton, JT | 1 |
| Vogl, SE | 1 |
| Pagano, M | 1 |
| Kaplan, BH | 1 |
| Greenwald, E | 1 |
| Arseneau, J | 1 |
| Bennett, B | 1 |
| Neijt, JP | 1 |
| ten Bokkel Huinink, WW | 1 |
| van der Burg, ME | 1 |
| van Oosterom, AT | 1 |
| Kooyman, CD | 1 |
| van Houwelingen, JC | 1 |
| Pinedo, HM | 1 |
| Chahinian, AP | 1 |
| Green, G | 1 |
| Chang, YC | 1 |
| Falkson, G | 1 |
| Tormey, DC | 2 |
| Crowley, J | 1 |
| Sørensen, P | 1 |
| Høyer, M | 1 |
| Jakobsen, A | 1 |
| Malmström, H | 1 |
| Havsteen, H | 1 |
| Bertelsen, K | 1 |
| Lichinitser, MR | 1 |
| Perevodchikova, NI | 1 |
| Garin, AM | 1 |
| Asserkritova, IV | 1 |
| Vaarik, GKh | 1 |
| Wilson, WL | 2 |
| Ryzin, JV | 1 |
| Weiss, AJ | 1 |
| Frelick, RW | 2 |
| Moss, SE | 1 |
| Andrews, NC | 1 |
| Nealon, TF | 1 |
| Bick, RL | 1 |
| Adams, T | 1 |
| Kline, JC | 1 |
| Palta, M | 1 |
| Davis, TE | 1 |
| Love, RR | 1 |
| Carbone, PP | 1 |
8 trials available for altretamine and Leukopenia
| Article | Year |
|---|---|
Hexamethylmelamine as a single agent in the treatment of small-cell carcinoma of the lung.
Topics: Adult; Aged; Altretamine; Carcinoma, Small Cell; Clinical Trials as Topic; Humans; Leukopenia; Lung | 1982 |
Cisplatin regimens and improved prognosis of patients with poorly differentiated ovarian cancer.
Topics: Altretamine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclo | 1983 |
cis-Platinum, adriamycin, and hexamethylmelamine versus cyclophosphamide in advanced ovarian carcinoma.
Topics: Adult; Aged; Altretamine; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Femal | 1983 |
A prospective randomized clinical trial of melphalan and cis-platinum versus hexamethylmelamine, adriamycin, and cyclophosphamide in advanced ovarian cancer.
Topics: Adult; Altretamine; Anemia; Antineoplastic Agents; Cisplatin; Clinical Trials as Topic; Cyclophospha | 1983 |
Mitomycin-C, etoposide, cisplatin, and hexamethylmelamine (MEPH) as a second-line regimen in lung cancer.
Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic; Cy | 1984 |
Phase II study of vinorelbine in the treatment of platinum-resistant ovarian carcinoma.
Topics: Adult; Aged; Altretamine; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Pr | 2001 |
A phase III study in lung carcinoma comparing hexamethyl-melamine (NSC 13875) to dibromodulcitol (NSC 104800) 1,2.
Topics: Adenocarcinoma; Altretamine; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Clinical Trials as Top | 1975 |
Preliminary report on the use of CCNU (NSC-79037), adriamycin (NSC-123127), and hexamethylmelamine (NSC-13875) in carcinoma of the lung.
Topics: Adult; Aged; Altretamine; Carcinoma, Squamous Cell; Clinical Trials as Topic; Doxorubicin; Drug Eval | 1976 |
6 other studies available for altretamine and Leukopenia
| Article | Year |
|---|---|
Cis-platin based combination chemotherapy for advanced ovarian cancer. High overall response rate with curative potential only in women with small tumor burdens.
Topics: Adult; Aged; Altretamine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cis | 1983 |
Combination chemotherapy with or without hexamethylmelamine in alkylating-agent resistant ovarian carcinoma.
Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Doxorubicin; Female; Humans; | 1984 |
Phase I--II evaluation of combination cyclophosphamide, 5-fluorouracil, hexamethylmelamine, and prednisone in advanced breast cancer.
Topics: Adenocarcinoma; Adult; Aged; Altretamine; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; | 1981 |
[Effectiveness of ftorafur and hexamethylmelamine in advanced breast cancer].
Topics: Adult; Altretamine; Breast Neoplasms; Drug Therapy, Combination; Female; Fluorouracil; Humans; Leuko | 1978 |
Short term high density systemic therapy for metastatic breast cancer.
Topics: Altretamine; Antineoplastic Agents; Bleomycin; Breast Neoplasms; Combined Modality Therapy; Doxorubi | 1985 |
Phase II trials of hexamethylmelamine, dianhydrogalactitol, razoxane, and beta-2'-deoxythioguanosine as single agents against advanced measurable tumors of the pancreas. Gastrointestinal Tumor Study Group.
Topics: Adenocarcinoma; Altretamine; Antineoplastic Agents; Deoxyguanosine; Dianhydrogalactitol; Drug Evalua | 1985 |