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altretamine and Carcinoma, Renal Cell

altretamine has been researched along with Carcinoma, Renal Cell in 2 studies

Altretamine: A hexamethyl-2,4,6-triamine derivative of 1,3,5-triazine.

Carcinoma, Renal Cell: A heterogeneous group of sporadic or hereditary carcinoma derived from cells of the KIDNEYS. There are several subtypes including the clear cells, the papillary, the chromophobe, the collecting duct, the spindle cells (sarcomatoid), or mixed cell-type carcinoma.

Research Excerpts

ExcerptRelevanceReference
"Altretamine was administered orally at a dosage of 260 mg/m2 days 1 through 14 with cycles repeated every 28 days."2.70Altretamine for the treatment of metastatic renal cell carcinoma. A Hoosier Oncology Group trial. ( Ansari, R; Helman, D; Loehrer, PJ; McClean, J; Picus, J; Sandler, A; Williams, SD; Zon, RT, 2001)
" HMM, PMM, and 2,2,4,6 TetrMM concentrations determined in RC tissues were much higher than the plasma values, as indicated by the pharmacokinetic parameters (Cmax and AUC)."1.27Pharmacokinetics and metabolism of hexamethylmelamine in mice bearing renal cell tumors. ( Abikhalil, F; Atassi, G; Dubois, J; Hanocq, M, 1988)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zon, RT1
McClean, J1
Helman, D1
Ansari, R1
Picus, J1
Sandler, A1
Williams, SD1
Loehrer, PJ1
Dubois, J1
Atassi, G1
Hanocq, M1
Abikhalil, F1

Trials

1 trial available for altretamine and Carcinoma, Renal Cell

ArticleYear
Altretamine for the treatment of metastatic renal cell carcinoma. A Hoosier Oncology Group trial.
    Investigational new drugs, 2001, Volume: 19, Issue:3

    Topics: Adult; Aged; Altretamine; Antineoplastic Agents, Alkylating; Carcinoma, Renal Cell; Female; Humans;

2001

Other Studies

1 other study available for altretamine and Carcinoma, Renal Cell

ArticleYear
Pharmacokinetics and metabolism of hexamethylmelamine in mice bearing renal cell tumors.
    Cancer chemotherapy and pharmacology, 1988, Volume: 22, Issue:4

    Topics: Altretamine; Animals; Biological Availability; Carcinoma, Renal Cell; Kidney Neoplasms; Male; Mathem

1988