altretamine has been researched along with Breast Neoplasms in 16 studies
Altretamine: A hexamethyl-2,4,6-triamine derivative of 1,3,5-triazine.
Breast Neoplasms: Tumors or cancer of the human BREAST.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A four-drug combination of intermittent high-dose cyclophosphamide with 5-fluorouracil, hexamethylmelamine, and prednisone was given to 19 patients with advanced breast cancer." | 7.66 | Phase I--II evaluation of combination cyclophosphamide, 5-fluorouracil, hexamethylmelamine, and prednisone in advanced breast cancer. ( Chang, YC; Crowley, J; Falkson, G; Tormey, DC, 1981) |
| "A four-drug combination of intermittent high-dose cyclophosphamide with 5-fluorouracil, hexamethylmelamine, and prednisone was given to 19 patients with advanced breast cancer." | 3.66 | Phase I--II evaluation of combination cyclophosphamide, 5-fluorouracil, hexamethylmelamine, and prednisone in advanced breast cancer. ( Chang, YC; Crowley, J; Falkson, G; Tormey, DC, 1981) |
| " Fifteen patients with sarcoma metastases in the soft tissue were treated with karminomycin in combnation with methotrexate and cyclophosphane." | 3.65 | [Carminomycin in drug combination in breast cancer and soft tissue sarcomas]. ( Assekritova, IV; Gorbunova, VA; Lichinitser, MR, 1977) |
| "Ninety-eight patients with metastatic breast cancer, heavily pretreated with other agents, were entered in a phase II trial of hexamethylmelamine (HEX)." | 2.65 | Phase II evaluation of hexamethylmelamine in advanced breast cancer: a Southwest Oncology Group study. ( Balcerzak, S; Fabian, CJ; Haut, A; Rasmussen, S; Smith, F; Stephens, R; Tranum, B, 1979) |
| "Five human breast carcinoma xenografts, MX-1, T-61, MCF-7, R-27 and Br-10, were inoculated subcutaneously into female nude mice." | 1.29 | In vivo antitumor activity of hexamethylmelamine against human breast, stomach and colon carcinoma xenografts. ( Furukawa, T; Kase, S; Kitajima, M; Koh, J; Kubota, T; Kuo, TH; Naito, Y; Saikawa, Y; Tanino, H; Yamada, Y, 1995) |
| "Twenty-three patients with metastatic breast carcinoma were induced with a complex systemic therapy regimen in an attempt to ascertain if a complete remission rate greater than 50% could be obtained with intensive drug exposure." | 1.27 | Short term high density systemic therapy for metastatic breast cancer. ( Carbone, PP; Davis, TE; Kline, JC; Love, RR; Palta, M; Tormey, DC, 1985) |
| "Eleven patients with metastatic breast cancer refractory to conventional therapy were treated with a combination of hexamethylmelamine 250 mg/m2 p." | 1.26 | An evaluation of hexamethylmelamine, cis-diamminedichloroplatinum, and mitomycin-C in advanced breast cancer. A pilot study of the Southeastern Cancer Study Group. ( Lawson, D; Moore, M; Smalley, R, 1980) |
| " The limited therapeutic benefit did not justify the toxicity produced, and suggested that intensive dosage schedules of vincristine, and use of low dose hexamethylmelamine during the time of anticipated hematologic nadir counts would not be of substantial benefit." | 1.26 | Adriamycin, vincristine, dibromodulcitol, and hexamethylmelamine in advanced previously treated breast cancer: an ECOG pilot study. ( Taylor, SG; Wolter, J, 1981) |
| "Its activity is most marked in ovarian cancer, lymphomas, and carcinoma of the cervix; the drug is also active in bronchogenic carcinoma and carcinoma of the breast." | 1.26 | Hexamethylmelamine. An evaluation of its role in the therapy of cancer. ( Carter, SK; Legha, SS; Slavik, M, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (81.25) | 18.7374 |
| 1990's | 3 (18.75) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Carter, SK | 2 |
| Lawson, D | 1 |
| Moore, M | 1 |
| Smalley, R | 1 |
| Taylor, SG | 1 |
| Wolter, J | 1 |
| Chang, YC | 1 |
| Falkson, G | 1 |
| Tormey, DC | 2 |
| Crowley, J | 1 |
| Quayle, JB | 1 |
| Tanino, H | 1 |
| Kubota, T | 1 |
| Yamada, Y | 1 |
| Koh, J | 1 |
| Kase, S | 1 |
| Furukawa, T | 1 |
| Kuo, TH | 1 |
| Saikawa, Y | 1 |
| Kitajima, M | 1 |
| Naito, Y | 1 |
| Yaguchi, S | 1 |
| Izumisawa, Y | 1 |
| Sato, M | 1 |
| Nakagane, T | 1 |
| Koshimizu, I | 1 |
| Sakita, K | 1 |
| Kato, M | 1 |
| Yoshioka, K | 1 |
| Sakato, M | 1 |
| Kawashima, S | 1 |
| Lichinitser, MR | 2 |
| Perevodchikova, NI | 1 |
| Garin, AM | 1 |
| Asserkritova, IV | 1 |
| Vaarik, GKh | 1 |
| Van Amburg, AL | 1 |
| Presant, CA | 1 |
| Vélez-García, E | 1 |
| Klahr, C | 1 |
| Fabian, CJ | 1 |
| Rasmussen, S | 1 |
| Stephens, R | 1 |
| Haut, A | 1 |
| Smith, F | 1 |
| Balcerzak, S | 1 |
| Tranum, B | 1 |
| Assekritova, IV | 1 |
| Gorbunova, VA | 1 |
| Denefrio, JM | 1 |
| Vogel, CL | 1 |
| Hill, GJ | 1 |
| Johnson, RO | 1 |
| Metter, G | 1 |
| Wilson, WL | 1 |
| Davis, HL | 1 |
| Grage, T | 1 |
| Fletcher, WS | 1 |
| Golomb, FM | 1 |
| Cruz, AB | 1 |
| Legha, SS | 1 |
| Slavik, M | 1 |
| Henderson, IC | 1 |
| Shapiro, CL | 1 |
| Kline, JC | 1 |
| Palta, M | 1 |
| Davis, TE | 1 |
| Love, RR | 1 |
| Carbone, PP | 1 |
2 reviews available for altretamine and Breast Neoplasms
| Article | Year |
|---|---|
New cytotoxic drugs for breast cancer and their clinical evaluation.
Topics: Altretamine; Aminoacridines; Amsacrine; Antineoplastic Agents; Breast Neoplasms; Clinical Trials as | 1980 |
Hexamethylmelamine use in the treatment of metastatic breast cancer.
Topics: Altretamine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms | 1991 |
3 trials available for altretamine and Breast Neoplasms
| Article | Year |
|---|---|
New cytotoxic drugs for breast cancer and their clinical evaluation.
Topics: Altretamine; Aminoacridines; Amsacrine; Antineoplastic Agents; Breast Neoplasms; Clinical Trials as | 1980 |
Phase I--II study of hexamethylmelamine plus dibromodulcitol in refractory carcinoma of the breast.
Topics: Adult; Aged; Altretamine; Breast Neoplasms; Clinical Trials as Topic; Drug Evaluation; Drug Therapy, | 1979 |
Phase II evaluation of hexamethylmelamine in advanced breast cancer: a Southwest Oncology Group study.
Topics: Aged; Altretamine; Breast Neoplasms; Drug Evaluation; Female; Humans; Middle Aged; Nausea; Nervous S | 1979 |
12 other studies available for altretamine and Breast Neoplasms
| Article | Year |
|---|---|
An evaluation of hexamethylmelamine, cis-diamminedichloroplatinum, and mitomycin-C in advanced breast cancer. A pilot study of the Southeastern Cancer Study Group.
Topics: Altretamine; Breast Neoplasms; Cisplatin; Drug Evaluation; Drug Therapy, Combination; Female; Humans | 1980 |
Adriamycin, vincristine, dibromodulcitol, and hexamethylmelamine in advanced previously treated breast cancer: an ECOG pilot study.
Topics: Aged; Altretamine; Breast Neoplasms; Doxorubicin; Drug Therapy, Combination; Female; Humans; Middle | 1981 |
Phase I--II evaluation of combination cyclophosphamide, 5-fluorouracil, hexamethylmelamine, and prednisone in advanced breast cancer.
Topics: Adenocarcinoma; Adult; Aged; Altretamine; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; | 1981 |
Tumour lysis as a factor affecting blood levels of CEA.
Topics: Altretamine; Animals; Breast Neoplasms; Carcinoembryonic Antigen; Cell Line; Colonic Neoplasms; Cycl | 1982 |
In vivo antitumor activity of hexamethylmelamine against human breast, stomach and colon carcinoma xenografts.
Topics: Altretamine; Animals; Antineoplastic Agents, Alkylating; Breast Neoplasms; Colonic Neoplasms; Dose-R | 1995 |
In vitro cytotoxicity of imidazolyl-1,3,5-triazine derivatives.
Topics: Altretamine; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Survival; Drug Screening Assays, | 1997 |
[Effectiveness of ftorafur and hexamethylmelamine in advanced breast cancer].
Topics: Adult; Altretamine; Breast Neoplasms; Drug Therapy, Combination; Female; Fluorouracil; Humans; Leuko | 1978 |
[Carminomycin in drug combination in breast cancer and soft tissue sarcomas].
Topics: Aged; Altretamine; Antibiotics, Antineoplastic; Breast Neoplasms; Carubicin; Cyclophosphamide; Drug | 1977 |
Phae II study of hexamethylmelamine in women with advanced breast cancer refractory to standard cytotoxic therapy.
Topics: Alkylating Agents; Altretamine; Breast Neoplasms; Drug Evaluation; Drug Resistance; Female; Humans; | 1978 |
Multimodal surgical adjuvant therapy for a broad spectrum of tumors in humans.?
Topics: Adult; Altretamine; Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Carmustine; Colonic Neo | 1976 |
Hexamethylmelamine. An evaluation of its role in the therapy of cancer.
Topics: Altretamine; Animals; Breast Neoplasms; Carcinoma, Bronchogenic; Chemical Phenomena; Chemistry; Drug | 1976 |
Short term high density systemic therapy for metastatic breast cancer.
Topics: Altretamine; Antineoplastic Agents; Bleomycin; Breast Neoplasms; Combined Modality Therapy; Doxorubi | 1985 |