alrestatin has been researched along with Diabetic Neuropathies in 6 studies
alrestatin: aldose reductase inhibitor; RN given refers to parent cpd; structure
Diabetic Neuropathies: Peripheral, autonomic, and cranial nerve disorders that are associated with DIABETES MELLITUS. These conditions usually result from diabetic microvascular injury involving small blood vessels that supply nerves (VASA NERVORUM). Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy (see OCULOMOTOR NERVE DISEASES); MONONEUROPATHY; mononeuropathy multiplex; diabetic amyotrophy; a painful POLYNEUROPATHY; autonomic neuropathy; and thoracoabdominal neuropathy. (From Adams et al., Principles of Neurology, 6th ed, p1325)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (83.33) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kador, PF | 1 |
| Kinoshita, JH | 1 |
| Sharpless, NE | 1 |
| Culebras, A | 1 |
| Alió, J | 1 |
| Herrera, JL | 1 |
| López-Fraile, MI | 1 |
| Handelsman, DJ | 1 |
| Turtle, JR | 1 |
| Fagius, J | 1 |
| Jameson, S | 1 |
| Pfeifer, MA | 1 |
| Schumer, MP | 1 |
| Gelber, DA | 1 |
| Gabbay, KH | 1 |
| Spack, N | 1 |
| Loo, S | 1 |
| Hirsch, HJ | 1 |
| Ackil, AA | 1 |
2 reviews available for alrestatin and Diabetic Neuropathies
| Article | Year |
|---|---|
Aldose reductase inhibitors: a potential new class of agents for the pharmacological control of certain diabetic complications.
Topics: Aldehyde Reductase; Animals; Binding Sites; Blood Glucose; Cataract; Chemical Phenomena; Chemistry; | 1985 |
Aldose reductase inhibitors: the end of an era or the need for different trial designs?
Topics: Aldehyde Reductase; Autonomic Nervous System; Diabetic Neuropathies; Enzyme Inhibitors; Humans; Imid | 1997 |
3 trials available for alrestatin and Diabetic Neuropathies
| Article | Year |
|---|---|
Clinical trial of an aldose reductase inhibitor in diabetic neuropathy.
Topics: Action Potentials; Adult; Aged; Aldehyde Reductase; Clinical Trials as Topic; Diabetic Neuropathies; | 1981 |
Effects of aldose reductase inhibitor treatment in diabetic polyneuropathy - a clinical and neurophysiological study.
Topics: Adult; Albuminuria; Aldehyde Reductase; Autonomic Nervous System; Clinical Trials as Topic; Diabetic | 1981 |
Aldose reductase inhibitors: the end of an era or the need for different trial designs?
Topics: Aldehyde Reductase; Autonomic Nervous System; Diabetic Neuropathies; Enzyme Inhibitors; Humans; Imid | 1997 |
2 other studies available for alrestatin and Diabetic Neuropathies
| Article | Year |
|---|---|
Effect of an aldose reductase inhibitor on diabetic peripheral neuropathy. Preliminary report.
Topics: Adult; Aged; Aldehyde Reductase; Diabetic Neuropathies; Female; Humans; Isoquinolines; Male; Middle | 1981 |
Aldose reductase inhibition: studies with alrestatin.
Topics: Absorption; Aged; Aldehyde Reductase; Diabetic Neuropathies; Drug Evaluation; Female; Half-Life; Hum | 1979 |