alprenolol has been researched along with Glioma in 8 studies
Alprenolol: One of the ADRENERGIC BETA-ANTAGONISTS used as an antihypertensive, anti-anginal, and anti-arrhythmic agent.
alprenolol : A secondary alcohol that is propan-2-ol substituted by a 2-allylphenoxy group at position 1 and an isopropylamino group at position 3. It is a beta-adrenergic antagonist used as a antihypertensive, anti-arrhythmia and a sympatholytic agent.
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The action of the (-)- and (+)-enantiomers of the beta-adrenoceptor blocking drug propranolol on the inward calcium current (ICa) was studied in single mouse neuroblastoma x rat glioma hybrid cells of clone 108CC5 by suction pipette technique for intracellular perfusion and voltage clamp." | 7.67 | [Calcium current effects in the presence and absence of propranolol on cloned neuroblastoma and glioma hybrid cells]. ( Bodewei, R; Fischer, W; Hering, S; Wollenberger, A, 1988) |
| "Rat glioma C6 cells, cultured in the presence of the tricyclic antidepressant desipramine, lost a significant number of beta-adrenergic receptors in a time- and dose-dependent manner." | 7.67 | Effect of the tricyclic antidepressant desipramine on beta-adrenergic receptors in cultured rat glioma C6 cells. ( Finberg, JP; Fishman, PH, 1987) |
| " Using [3H]DHA and unlabeled L-alprenolol, a substantial amount of over 64% specific binding of beta-adrenergic receptor has been identified on the neuroblastoma x glioma hybrid NG108-15 cell, which has been proven to display numerous functional characteristics of intact neurons." | 3.68 | Identification and characterization of the beta-adrenergic receptor on neuroblastoma x glioma hybrid NG108-15 cells. ( Cheng, KW; Ghahary, A, 1990) |
| "The action of the (-)- and (+)-enantiomers of the beta-adrenoceptor blocking drug propranolol on the inward calcium current (ICa) was studied in single mouse neuroblastoma x rat glioma hybrid cells of clone 108CC5 by suction pipette technique for intracellular perfusion and voltage clamp." | 3.67 | [Calcium current effects in the presence and absence of propranolol on cloned neuroblastoma and glioma hybrid cells]. ( Bodewei, R; Fischer, W; Hering, S; Wollenberger, A, 1988) |
| " The selectivity of [125I]iodopindolol, [125I]iodocyanopindolol, [125I]iodohydroxybenzylpindolol and [3H]dihydroalprenolol for beta-1 and beta-2 adrenergic receptors was assessed by inhibiting the binding of each radioligand with the beta-1-selective unlabeled ligand ICI 89,406 at increasing concentrations of the radioligand, using membranes prepared from C6 glioma cells, which have both beta-1 and beta-2 adrenergic receptors." | 3.67 | Quantitative analysis of the selectivity of radioligands for subtypes of beta adrenergic receptors. ( McGonigle, P; Molinoff, PB; Neve, KA, 1986) |
| "Rat glioma C6 cells, cultured in the presence of the tricyclic antidepressant desipramine, lost a significant number of beta-adrenergic receptors in a time- and dose-dependent manner." | 3.67 | Effect of the tricyclic antidepressant desipramine on beta-adrenergic receptors in cultured rat glioma C6 cells. ( Finberg, JP; Fishman, PH, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (75.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Giron, LT | 1 |
| Davis, JN | 1 |
| Kim, GD | 1 |
| Milligan, G | 1 |
| Lucas, M | 1 |
| Bockaert, J | 1 |
| Ghahary, A | 1 |
| Cheng, KW | 1 |
| Bodewei, R | 1 |
| Fischer, W | 1 |
| Hering, S | 1 |
| Wollenberger, A | 1 |
| Affolter, H | 1 |
| Hertel, C | 1 |
| Jaeggi, K | 1 |
| Portenier, M | 1 |
| Staehelin, M | 1 |
| Neve, KA | 1 |
| McGonigle, P | 1 |
| Molinoff, PB | 1 |
| Fishman, PH | 1 |
| Finberg, JP | 1 |
8 other studies available for alprenolol and Glioma
| Article | Year |
|---|---|
(-)-[3H]Dihydroalprenolol binding in subcellular fractions of rat cortex following noradrenergic denervation.
Topics: Alprenolol; Animals; Brain Neoplasms; Cerebral Cortex; Denervation; Dihydroalprenolol; Glioma; Kinet | 1981 |
Receptor availability defines the extent of agonist-mediated G-protein down-regulation in neuroblastoma x glioma hybrid cells transfected to express the beta 2-adrenoceptor.
Topics: Adenylyl Cyclases; Adrenergic beta-2 Receptor Antagonists; Alprenolol; Down-Regulation; Gene Express | 1994 |
Use of (-)-[3H]dihydroalprenolol to study beta adrenergic receptor-adenylate cyclase coupling in C6 glioma cells: role of 5'-guanylylimidodiphosphate.
Topics: Adenylyl Cyclases; Alprenolol; Binding Sites; Clone Cells; Drug Interactions; Enzyme Activation; Gli | 1977 |
Identification and characterization of the beta-adrenergic receptor on neuroblastoma x glioma hybrid NG108-15 cells.
Topics: Alprenolol; Bucladesine; Catecholamines; Cell Differentiation; Dihydroalprenolol; Glioma; Hybrid Cel | 1990 |
[Calcium current effects in the presence and absence of propranolol on cloned neuroblastoma and glioma hybrid cells].
Topics: Alprenolol; Animals; Calcium Channels; Cells, Cultured; Clone Cells; Glioma; Hybrid Cells; Mice; Neu | 1988 |
(-)-S-[3H]CGP-12177 and its use to determine the rate constants of unlabeled beta-adrenergic antagonists.
Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Cell Line; Computers; Glioma; Kinetics; Pindolol; | 1985 |
Quantitative analysis of the selectivity of radioligands for subtypes of beta adrenergic receptors.
Topics: Alprenolol; Animals; Cell Line; Dihydroalprenolol; Dose-Response Relationship, Drug; Glioma; Heart A | 1986 |
Effect of the tricyclic antidepressant desipramine on beta-adrenergic receptors in cultured rat glioma C6 cells.
Topics: Adenylyl Cyclases; Alprenolol; Animals; Cells, Cultured; Cyclic AMP; Desipramine; Glioma; Isoprotere | 1987 |