alprenolol has been researched along with Glial Cell Tumors in 8 studies
Alprenolol: One of the ADRENERGIC BETA-ANTAGONISTS used as an antihypertensive, anti-anginal, and anti-arrhythmic agent.
alprenolol : A secondary alcohol that is propan-2-ol substituted by a 2-allylphenoxy group at position 1 and an isopropylamino group at position 3. It is a beta-adrenergic antagonist used as a antihypertensive, anti-arrhythmia and a sympatholytic agent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The action of the (-)- and (+)-enantiomers of the beta-adrenoceptor blocking drug propranolol on the inward calcium current (ICa) was studied in single mouse neuroblastoma x rat glioma hybrid cells of clone 108CC5 by suction pipette technique for intracellular perfusion and voltage clamp." | 7.67 | [Calcium current effects in the presence and absence of propranolol on cloned neuroblastoma and glioma hybrid cells]. ( Bodewei, R; Fischer, W; Hering, S; Wollenberger, A, 1988) |
| "Rat glioma C6 cells, cultured in the presence of the tricyclic antidepressant desipramine, lost a significant number of beta-adrenergic receptors in a time- and dose-dependent manner." | 7.67 | Effect of the tricyclic antidepressant desipramine on beta-adrenergic receptors in cultured rat glioma C6 cells. ( Finberg, JP; Fishman, PH, 1987) |
| " Using [3H]DHA and unlabeled L-alprenolol, a substantial amount of over 64% specific binding of beta-adrenergic receptor has been identified on the neuroblastoma x glioma hybrid NG108-15 cell, which has been proven to display numerous functional characteristics of intact neurons." | 3.68 | Identification and characterization of the beta-adrenergic receptor on neuroblastoma x glioma hybrid NG108-15 cells. ( Cheng, KW; Ghahary, A, 1990) |
| "The action of the (-)- and (+)-enantiomers of the beta-adrenoceptor blocking drug propranolol on the inward calcium current (ICa) was studied in single mouse neuroblastoma x rat glioma hybrid cells of clone 108CC5 by suction pipette technique for intracellular perfusion and voltage clamp." | 3.67 | [Calcium current effects in the presence and absence of propranolol on cloned neuroblastoma and glioma hybrid cells]. ( Bodewei, R; Fischer, W; Hering, S; Wollenberger, A, 1988) |
| " The selectivity of [125I]iodopindolol, [125I]iodocyanopindolol, [125I]iodohydroxybenzylpindolol and [3H]dihydroalprenolol for beta-1 and beta-2 adrenergic receptors was assessed by inhibiting the binding of each radioligand with the beta-1-selective unlabeled ligand ICI 89,406 at increasing concentrations of the radioligand, using membranes prepared from C6 glioma cells, which have both beta-1 and beta-2 adrenergic receptors." | 3.67 | Quantitative analysis of the selectivity of radioligands for subtypes of beta adrenergic receptors. ( McGonigle, P; Molinoff, PB; Neve, KA, 1986) |
| "Rat glioma C6 cells, cultured in the presence of the tricyclic antidepressant desipramine, lost a significant number of beta-adrenergic receptors in a time- and dose-dependent manner." | 3.67 | Effect of the tricyclic antidepressant desipramine on beta-adrenergic receptors in cultured rat glioma C6 cells. ( Finberg, JP; Fishman, PH, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (75.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Giron, LT | 1 |
| Davis, JN | 1 |
| Kim, GD | 1 |
| Milligan, G | 1 |
| Lucas, M | 1 |
| Bockaert, J | 1 |
| Ghahary, A | 1 |
| Cheng, KW | 1 |
| Bodewei, R | 1 |
| Fischer, W | 1 |
| Hering, S | 1 |
| Wollenberger, A | 1 |
| Affolter, H | 1 |
| Hertel, C | 1 |
| Jaeggi, K | 1 |
| Portenier, M | 1 |
| Staehelin, M | 1 |
| Neve, KA | 1 |
| McGonigle, P | 1 |
| Molinoff, PB | 1 |
| Fishman, PH | 1 |
| Finberg, JP | 1 |
8 other studies available for alprenolol and Glial Cell Tumors
| Article | Year |
|---|---|
(-)-[3H]Dihydroalprenolol binding in subcellular fractions of rat cortex following noradrenergic denervation.
Topics: Alprenolol; Animals; Brain Neoplasms; Cerebral Cortex; Denervation; Dihydroalprenolol; Glioma; Kinet | 1981 |
Receptor availability defines the extent of agonist-mediated G-protein down-regulation in neuroblastoma x glioma hybrid cells transfected to express the beta 2-adrenoceptor.
Topics: Adenylyl Cyclases; Adrenergic beta-2 Receptor Antagonists; Alprenolol; Down-Regulation; Gene Express | 1994 |
Use of (-)-[3H]dihydroalprenolol to study beta adrenergic receptor-adenylate cyclase coupling in C6 glioma cells: role of 5'-guanylylimidodiphosphate.
Topics: Adenylyl Cyclases; Alprenolol; Binding Sites; Clone Cells; Drug Interactions; Enzyme Activation; Gli | 1977 |
Identification and characterization of the beta-adrenergic receptor on neuroblastoma x glioma hybrid NG108-15 cells.
Topics: Alprenolol; Bucladesine; Catecholamines; Cell Differentiation; Dihydroalprenolol; Glioma; Hybrid Cel | 1990 |
[Calcium current effects in the presence and absence of propranolol on cloned neuroblastoma and glioma hybrid cells].
Topics: Alprenolol; Animals; Calcium Channels; Cells, Cultured; Clone Cells; Glioma; Hybrid Cells; Mice; Neu | 1988 |
(-)-S-[3H]CGP-12177 and its use to determine the rate constants of unlabeled beta-adrenergic antagonists.
Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Cell Line; Computers; Glioma; Kinetics; Pindolol; | 1985 |
Quantitative analysis of the selectivity of radioligands for subtypes of beta adrenergic receptors.
Topics: Alprenolol; Animals; Cell Line; Dihydroalprenolol; Dose-Response Relationship, Drug; Glioma; Heart A | 1986 |
Effect of the tricyclic antidepressant desipramine on beta-adrenergic receptors in cultured rat glioma C6 cells.
Topics: Adenylyl Cyclases; Alprenolol; Animals; Cells, Cultured; Cyclic AMP; Desipramine; Glioma; Isoprotere | 1987 |