Compounds > alprenolol
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alprenolol and Germinoblastoma

alprenolol has been researched along with Germinoblastoma in 5 studies

Alprenolol: One of the ADRENERGIC BETA-ANTAGONISTS used as an antihypertensive, anti-anginal, and anti-arrhythmic agent.
alprenolol : A secondary alcohol that is propan-2-ol substituted by a 2-allylphenoxy group at position 1 and an isopropylamino group at position 3. It is a beta-adrenergic antagonist used as a antihypertensive, anti-arrhythmia and a sympatholytic agent.

Research Excerpts

ExcerptRelevanceReference
"Bromoacetylalprenololmenthane was found to inhibit hormone-induced beta-adrenergic receptor internalization in a dose-dependent fashion in S49 lymphoma cells, besides its known ability to bind to beta-receptors irreversibly."3.67Bromoacetylalprenololmenthane binding to beta-receptors modulates the rate of hormone-induced internalization but not desensitization in S49 cells. ( Box, RJ; Staehelin, M, 1987)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19905 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Insel, PA4
Sanda, M1
Mahan, LC3
Hughes, RJ1
Box, RJ1
Staehelin, M1

Other Studies

5 other studies available for alprenolol and Germinoblastoma

ArticleYear
Temperature-dependent changes in binding to beta-adrenergic receptors of intact S49 lymphoma cells. Implications for the state of the receptor that activates adenylate cyclase under physiological conditions.
    The Journal of biological chemistry, 1979, Jul-25, Volume: 254, Issue:14

    Topics: Adenylyl Cyclases; Alprenolol; Binding, Competitive; Cell Line; Cyclic AMP; Enzyme Activation; Isopr

1979
Expression of beta-adrenergic receptors in synchronous and asynchronous S49 lymphoma cells. I. Receptor metabolism after irreversible blockade of receptors and in cells traversing the cell division cycle.
    Molecular pharmacology, 1986, Volume: 29, Issue:1

    Topics: Adrenergic beta-Antagonists; Alprenolol; Cell Cycle; Cell Division; Cell Line; Centrifugation; Human

1986
Certain beta-blockers can decrease beta-adrenergic receptor number: II. Down-regulation of receptor number by alprenolol and propranolol in cultured lymphoma and muscle cells.
    Circulation research, 1988, Volume: 63, Issue:2

    Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Cell Line; Cyclic AMP; Humans; Lymphoma; Muscles;

1988
Expression of beta-adrenergic receptors in synchronous and asynchronous S49 lymphoma cells. II. Relationship between receptor number and response.
    Molecular pharmacology, 1986, Volume: 29, Issue:1

    Topics: Adenylyl Cyclases; Alprenolol; Cell Cycle; Cell Line; Colforsin; Cyclic AMP; GTP-Binding Proteins; G

1986
Bromoacetylalprenololmenthane binding to beta-receptors modulates the rate of hormone-induced internalization but not desensitization in S49 cells.
    FEBS letters, 1987, Apr-20, Volume: 214, Issue:2

    Topics: Alprenolol; Cell Line; Cell Membrane; Cyclic AMP; Isoproterenol; Kinetics; Lymphoma; Propanolamines;

1987