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alprenolol and Coronary Disease

alprenolol has been researched along with Coronary Disease in 16 studies

Alprenolol: One of the ADRENERGIC BETA-ANTAGONISTS used as an antihypertensive, anti-anginal, and anti-arrhythmic agent.
alprenolol : A secondary alcohol that is propan-2-ol substituted by a 2-allylphenoxy group at position 1 and an isopropylamino group at position 3. It is a beta-adrenergic antagonist used as a antihypertensive, anti-arrhythmia and a sympatholytic agent.

Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.

Research Excerpts

ExcerptRelevanceReference
"In 14 patients with coronary heart disease the effect of long-term treatment (mean 16 months, range 12-33) with alprenolol on platelet function and fibrinolytic activity was studied."9.05Effect of long-term beta-blockade with alprenolol on platelet function and fibrinolytic activity in patients with coronary heart disease. ( Dalsgaard-Nielsen, J; Gormsen, J; Jürgensen, HJ; Kjøller, E, 1981)
"The effects of nadolol on experimental arrhythmias were investigated and compared with those of propranolol and alprenolol."7.67Anti-arrhythmic effect of nadolol in experimental arrhythmias: comparison with propranolol and alprenolol. ( Hashimoto, H; Nakashima, M; Oguro, K; Sogabe, K; Takiguchi, Y, 1985)
"In 14 patients with coronary heart disease the effect of long-term treatment (mean 16 months, range 12-33) with alprenolol on platelet function and fibrinolytic activity was studied."5.05Effect of long-term beta-blockade with alprenolol on platelet function and fibrinolytic activity in patients with coronary heart disease. ( Dalsgaard-Nielsen, J; Gormsen, J; Jürgensen, HJ; Kjøller, E, 1981)
"The effects of nadolol on experimental arrhythmias were investigated and compared with those of propranolol and alprenolol."3.67Anti-arrhythmic effect of nadolol in experimental arrhythmias: comparison with propranolol and alprenolol. ( Hashimoto, H; Nakashima, M; Oguro, K; Sogabe, K; Takiguchi, Y, 1985)
"The author describes the notions that led to initiation of controlled trials of long-term medication with antiarrhythmic drugs following myocardial infarction, and reviews reports of controlled trials with diphenylhydantoin, alprenolol, and procaine amide."3.65Arrhythmia prophylaxis: Long-term suppressive medication. ( Lovell, RR, 1975)
"The effect is critically reviewed of chronic administration of beta-adrenoreceptor antagonists on morbidity and mortality in angina pectoris and myocardial infarction."1.26The effect of beta-adrenoreceptive antagonists on the morbidity and mortality in cardiovascular disease. ( Fitzgerald, JD, 1976)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199015 (93.75)18.7374
1990's0 (0.00)18.2507
2000's1 (6.25)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Callaerts-Vegh, Z1
Evans, KL1
Shipley, GL1
Davies, PJ1
Cuba, DL1
Gurji, HA1
Giles, H1
Bond, RA1
Johansson, SR1
McCall, M1
Wilhelmsson, C1
Vedin, JA1
Moses, JW1
Borer, JS1
Hjalmarson, A1
Jürgensen, HJ2
Nielsen, JD1
Gormsen, J2
Kjøller, E2
Frishman, WH1
Furberg, CD1
Friedewald, WT1
Rasmussen, SL1
Pedersen, F1
Nielsen, PB1
Dalsgaard-Nielsen, J1
Guse, PA1
Gaide, MS1
Myerburg, RJ1
Epstein, K1
Gelband, H1
Bassett, AL1
Storstein, L1
Fitzgerald, JD1
Tannenbaum, H1
Lovell, RR1
Dintenfass, L1
Lake, R1
Bailey, IK1
Anderson, SD1
Rozea, PJ1
Bernstein, L1
Nyberg, G1
Korner, PI1
Nakashima, M1
Takiguchi, Y1
Oguro, K1
Sogabe, K1
Hashimoto, H1

Reviews

4 reviews available for alprenolol and Coronary Disease

ArticleYear
Beta-adrenergic antagonists in the treatment of patients with heart disease.
    Disease-a-month : DM, 1981, Volume: 27, Issue:9

    Topics: Acebutolol; Adrenergic beta-Agonists; Alprenolol; Animals; Arrhythmias, Cardiac; Bronchial Spasm; Ca

1981
Beta blocking agents: current status in the prevention of sudden coronary death.
    Annals of the New York Academy of Sciences, 1982, Volume: 382

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Alprenolol; Atenolol; Clinical Trials as Topic; Coronary D

1982
Beta-adrenergic blockade for survivors of acute myocardial infarction.
    The New England journal of medicine, 1984, Mar-29, Volume: 310, Issue:13

    Topics: Adrenergic beta-Antagonists; Aged; Alprenolol; Arrhythmias, Cardiac; Clinical Trials as Topic; Coron

1984
[Long-term utilization of beta-blockers in arterial hypertension].
    La Nouvelle presse medicale, 1978, Sep-20, Volume: 7, Issue:31

    Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Blood Pressure; Coronary Disease; Drug Toleranc

1978

Trials

5 trials available for alprenolol and Coronary Disease

ArticleYear
Duration of action of beta blockers.
    Clinical pharmacology and therapeutics, 1980, Volume: 27, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Alprenolol; Atenolol; Blood Pressure; Coronary Disease; Heart Ra

1980
Beta blocking agents: current status in the prevention of sudden coronary death.
    Annals of the New York Academy of Sciences, 1982, Volume: 382

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Alprenolol; Atenolol; Clinical Trials as Topic; Coronary D

1982
Beta-adrenergic blockade for survivors of acute myocardial infarction.
    The New England journal of medicine, 1984, Mar-29, Volume: 310, Issue:13

    Topics: Adrenergic beta-Antagonists; Aged; Alprenolol; Arrhythmias, Cardiac; Clinical Trials as Topic; Coron

1984
Effect of long-term beta-blockade with alprenolol on platelet function and fibrinolytic activity in patients with coronary heart disease.
    European journal of clinical pharmacology, 1981, Volume: 20, Issue:4

    Topics: Adenosine Diphosphate; Adult; Aged; Alprenolol; Blood Platelets; Clinical Trials as Topic; Coronary

1981
Letter: Beta blocker and blood viscosity.
    Lancet (London, England), 1976, May-08, Volume: 1, Issue:7967

    Topics: Alprenolol; Blood Viscosity; Coronary Disease; Erythrocytes; Humans; Male; Middle Aged

1976

Other Studies

9 other studies available for alprenolol and Coronary Disease

ArticleYear
Effects of different beta adrenoceptor ligands in mice with permanent occlusion of the left anterior descending coronary artery.
    British journal of pharmacology, 2003, Volume: 138, Issue:8

    Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Carbazoles; Carvedilol; Coronary Disease; Coronary

2003
[Thrombocyte aggregation and fibrinolytic activity during long-term beta-block therapy].
    Ugeskrift for laeger, 1982, Nov-22, Volume: 144, Issue:47

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Alprenolol; Coronary Disease; Female; Fibrinolysis; Humans

1982
Systolic time intervals during long-term beta-blockade with alprenol in ischaemic heart disease.
    European journal of clinical pharmacology, 1983, Volume: 25, Issue:4

    Topics: Aged; Alprenolol; Blood Pressure; Coronary Disease; Double-Blind Method; Drug Evaluation; Electrocar

1983
Electrophysiological effects of alprenolol on depressed canine myocardium.
    Cardiovascular research, 1980, Volume: 14, Issue:11

    Topics: Action Potentials; Alprenolol; Animals; Coronary Disease; Dogs; Heart; Heart Ventricles; Purkinje Fi

1980
Delay of onset of second degree pacemaker block by beta-blockade in patients with P-synchronous pacemakers.
    Acta medica Scandinavica, 1981, Volume: 209, Issue:5

    Topics: Adult; Aged; Alprenolol; Coronary Disease; Exercise Test; Female; Heart Rate; Humans; Male; Middle A

1981
The effect of beta-adrenoreceptive antagonists on the morbidity and mortality in cardiovascular disease.
    Postgraduate medical journal, 1976, Volume: 52, Issue:614

    Topics: Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Animals; Coronary Disease; Dogs; Follow-Up

1976
Arrhythmia prophylaxis: Long-term suppressive medication.
    Circulation, 1975, Volume: 52, Issue:6 Suppl

    Topics: Acute Disease; Aged; Alprenolol; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Coronary Diseas

1975
Effect of beta-adrenergic blockade with alprenolol on ST-segment depression and circulatory dynamics during exercise in patients with effort angina.
    American heart journal, 1976, Volume: 92, Issue:4

    Topics: Adult; Alprenolol; Angina Pectoris; Blood Pressure; Cardiac Output; Coronary Disease; Exercise Test;

1976
Anti-arrhythmic effect of nadolol in experimental arrhythmias: comparison with propranolol and alprenolol.
    Journal of pharmacobio-dynamics, 1985, Volume: 8, Issue:1

    Topics: Alprenolol; Anesthesia; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Disease; Dog

1985