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alprenolol and Cardiac Hypertrophy

alprenolol has been researched along with Cardiac Hypertrophy in 3 studies

Alprenolol: One of the ADRENERGIC BETA-ANTAGONISTS used as an antihypertensive, anti-anginal, and anti-arrhythmic agent.
alprenolol : A secondary alcohol that is propan-2-ol substituted by a 2-allylphenoxy group at position 1 and an isopropylamino group at position 3. It is a beta-adrenergic antagonist used as a antihypertensive, anti-arrhythmia and a sympatholytic agent.

Cardiac Hypertrophy: Enlargement of the HEART due to chamber HYPERTROPHY, an increase in wall thickness without an increase in the number of cells (MYOCYTES, CARDIAC). It is the result of increase in myocyte size, mitochondrial and myofibrillar mass, as well as changes in extracellular matrix.

Research Excerpts

ExcerptRelevanceReference
"Development of cardiac hypertrophy is associated with depletion of endogenous catecholamine stores and increased inotropic response to exogenous catecholamines."1.26Increased number of beta-adrenergic receptors in the hypertrophied myocardium. ( Limas, CJ, 1979)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ahlmark, G1
Saetre, H1
Harri, MN1
Limas, CJ1

Trials

1 trial available for alprenolol and Cardiac Hypertrophy

ArticleYear
Long-term treatment with beta-blockers after myocardial infarction.
    European journal of clinical pharmacology, 1976, Jun-15, Volume: 10, Issue:2

    Topics: Adult; Aged; Alprenolol; Angina Pectoris; Arrhythmias, Cardiac; Blood Pressure; Cardiomegaly; Clinic

1976

Other Studies

2 other studies available for alprenolol and Cardiac Hypertrophy

ArticleYear
Metabolic and cardiovascular responses to prolonged noradrenaline load and their antagonism by beta blockade in the rat.
    Acta physiologica Scandinavica, 1978, Volume: 104, Issue:4

    Topics: Adipose Tissue, Brown; Adrenal Glands; Alprenolol; Animals; Blood Pressure; Body Temperature; Body W

1978
Increased number of beta-adrenergic receptors in the hypertrophied myocardium.
    Biochimica et biophysica acta, 1979, Nov-15, Volume: 588, Issue:1

    Topics: Alprenolol; Animals; Binding, Competitive; Cardiomegaly; Dihydroalprenolol; Isoproterenol; Male; Rat

1979