Page last updated: 2024-10-22

alprazolam and Vomiting

alprazolam has been researched along with Vomiting in 14 studies

Alprazolam: A triazolobenzodiazepine compound with antianxiety and sedative-hypnotic actions, that is efficacious in the treatment of PANIC DISORDERS, with or without AGORAPHOBIA, and in generalized ANXIETY DISORDERS. (From AMA Drug Evaluations Annual, 1994, p238)
alprazolam : A member of the class of triazolobenzodiazepines that is 4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine carrying methyl, phenyl and chloro substituents at positions 1, 6 and 8 respectively. Alprazolam is only found in individuals that have taken this drug.

Vomiting: The forcible expulsion of the contents of the STOMACH through the MOUTH.

Research Excerpts

ExcerptRelevanceReference
"Alprazolam, a newer benzodiazepine, may be useful in the control of nausea and vomiting in breast cancer patients."9.11Alprazolam significantly improves the efficacy of granisetron in the prophylaxis of emesis secondary to moderately emetogenic chemotherapy in patients with breast cancer. ( Abali, H; Guler, N; Oyan, B, 2005)
" We have studied the role of a benzodiazepine (alprazolam: A) in addition to granisetron for controlling emesis in patients treated with moderately emetogenic chemotherapy for malignant lymphomas according to an anxiety scale (Covi score)."9.09Granisetron plus or minus alprazolam for emesis prevention in chemotherapy of lymphomas: a randomized multicenter trial. Granisetron Trialists Group. ( Bauduer, F; Coiffier, B; Desablens, B, 1999)
"The usefulness of alprazolam (minor tranquilizer) used in combination with metoclopramide plus methylprednisolone for the prevention and control of emesis induced by chemotherapies, including 5-day continuous intravenous infusion of cisplatin (25 mg/m2/day) for advanced lung cancer, was evaluated using a double-blind randomized crossover design."9.07Antiemetic efficacy of alprazolam in the combination of metoclopramide plus methylprednisolone. Double-blind randomized crossover study in patients with cisplatin-induced emesis. ( Mori, K; Saito, Y; Tominaga, K, 1993)
"Usefulness of alprazolam for control of chemotherapy-induced emesis including 5-day continuous intravenous infusion of cisplatin for advanced lung cancer was evaluated by a randomized crossover design."9.07[Usefulness of alprazolam in controlling cisplatin-induced emesis]. ( Miyazawa, N; Mori, K; Saitoh, Y; Tominaga, K; Yokoi, K, 1991)
"To evaluate the efficacy of a combined therapy of prednisolone and alprazolam for controlling cisplatin-induced delayed emesis, a study involving 14 non-small cell lung cancer patients receiving cisplatin (80 mg/m2) was conducted."7.68[A combined anti-emesis therapy of oral prednisolone and alprazolam for cisplatin-induced delayed emesis]. ( Horio, Y; Iwahara, T; Minami, H; Sakai, S; Shibagaki, T; Shimokata, K; Watanabe, A, 1990)
"Alprazolam, a newer benzodiazepine, may be useful in the control of nausea and vomiting in breast cancer patients."5.11Alprazolam significantly improves the efficacy of granisetron in the prophylaxis of emesis secondary to moderately emetogenic chemotherapy in patients with breast cancer. ( Abali, H; Guler, N; Oyan, B, 2005)
" We have studied the role of a benzodiazepine (alprazolam: A) in addition to granisetron for controlling emesis in patients treated with moderately emetogenic chemotherapy for malignant lymphomas according to an anxiety scale (Covi score)."5.09Granisetron plus or minus alprazolam for emesis prevention in chemotherapy of lymphomas: a randomized multicenter trial. Granisetron Trialists Group. ( Bauduer, F; Coiffier, B; Desablens, B, 1999)
"The purpose of our study was to evaluate the effectiveness of alprazolam (APZ) as an adjuvant drug to ondansentron against cisplatin-induced emesis."5.07Comparison of ondansentron (GR 38032F) versus ondansentron plus alprazolam as antiemetic prophylaxis during cisplatin-containing chemotherapy. ( Bacoyiannis, C; Charalambidis, G; Karabelis, A; Kosmidis, P; Mylonakis, N; Pagou, M; Tsavaris, N, 1994)
"The usefulness of alprazolam (minor tranquilizer) used in combination with metoclopramide plus methylprednisolone for the prevention and control of emesis induced by chemotherapies, including 5-day continuous intravenous infusion of cisplatin (25 mg/m2/day) for advanced lung cancer, was evaluated using a double-blind randomized crossover design."5.07Antiemetic efficacy of alprazolam in the combination of metoclopramide plus methylprednisolone. Double-blind randomized crossover study in patients with cisplatin-induced emesis. ( Mori, K; Saito, Y; Tominaga, K, 1993)
"Usefulness of alprazolam for control of chemotherapy-induced emesis including 5-day continuous intravenous infusion of cisplatin for advanced lung cancer was evaluated by a randomized crossover design."5.07[Usefulness of alprazolam in controlling cisplatin-induced emesis]. ( Miyazawa, N; Mori, K; Saitoh, Y; Tominaga, K; Yokoi, K, 1991)
"Olanzapine antagonizes multiple receptors and has potential to treat a host of symptoms including nausea, anorexia, anxiety, and insomnia, but healthcare providers should be mindful of potential risks and unclear benefits for off-label indications."4.31Benefits and risks of off-label olanzapine use for symptom management in cancer patients-a case report. ( Amaram-Davila, JS; Bruera, E; Dev, R; Fortuno, ES; Haider, A, 2023)
"To evaluate the efficacy of a combined therapy of prednisolone and alprazolam for controlling cisplatin-induced delayed emesis, a study involving 14 non-small cell lung cancer patients receiving cisplatin (80 mg/m2) was conducted."3.68[A combined anti-emesis therapy of oral prednisolone and alprazolam for cisplatin-induced delayed emesis]. ( Horio, Y; Iwahara, T; Minami, H; Sakai, S; Shibagaki, T; Shimokata, K; Watanabe, A, 1990)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.14)18.7374
1990's9 (64.29)18.2507
2000's3 (21.43)29.6817
2010's0 (0.00)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Dev, R1
Fortuno, ES1
Amaram-Davila, JS1
Haider, A1
Bruera, E1
Abali, H1
Oyan, B1
Guler, N1
Tsavaris, N3
Kosmas, C1
Kopterides, P1
Vadiaka, M1
Kosmas, N1
Skopelitis, H1
Karadima, D1
Kolliokosta, G1
Tzima, E1
Loukeris, D1
Pagouni, E1
Batziou, E1
Xyla, V1
Koufos, C1
Weltzin, TE1
Bulik, CM1
McConaha, CW1
Kaye, WH1
Charalambidis, G1
Pagou, M1
Karabelis, A1
Mylonakis, N2
Bacoyiannis, C1
Kosmidis, P2
Mori, K2
Saito, Y1
Tominaga, K2
Loeb, P1
Adnet, P1
Boittiaux, P1
Forget, AP1
Mille, FX1
Bauduer, F1
Coiffier, B1
Desablens, B1
Lehoczky, O1
Bagaméri, A1
Sárosi, Z1
Kulcsár, T1
Pulay, T1
Tsoutsos, H1
Bacoyannis, C1
Karvounis, N1
Kozatsani-Halividi, D1
Tsaroucha-Noutsou, E1
Klinaki, A1
Saitoh, Y1
Yokoi, K1
Miyazawa, N1
Salles, G1
Archimbaud, E1
Thomas, X1
Fiere, D1
Watanabe, A1
Horio, Y1
Minami, H1
Shibagaki, T1
Iwahara, T1
Sakai, S1
Shimokata, K1
Greenberg, DB1
Surman, OS1
Clarke, J1
Baer, L1

Trials

6 trials available for alprazolam and Vomiting

ArticleYear
Alprazolam significantly improves the efficacy of granisetron in the prophylaxis of emesis secondary to moderately emetogenic chemotherapy in patients with breast cancer.
    Chemotherapy, 2005, Volume: 51, Issue:5

    Topics: Alprazolam; Anthracyclines; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Breast Neop

2005
Comparison of ondansentron (GR 38032F) versus ondansentron plus alprazolam as antiemetic prophylaxis during cisplatin-containing chemotherapy.
    American journal of clinical oncology, 1994, Volume: 17, Issue:6

    Topics: Adult; Aged; Alprazolam; Cisplatin; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Na

1994
Antiemetic efficacy of alprazolam in the combination of metoclopramide plus methylprednisolone. Double-blind randomized crossover study in patients with cisplatin-induced emesis.
    American journal of clinical oncology, 1993, Volume: 16, Issue:4

    Topics: Adult; Aged; Alprazolam; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non

1993
Granisetron plus or minus alprazolam for emesis prevention in chemotherapy of lymphomas: a randomized multicenter trial. Granisetron Trialists Group.
    Leukemia & lymphoma, 1999, Volume: 34, Issue:3-4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Antiemetics; Antineopla

1999
[Usefulness of alprazolam in controlling cisplatin-induced emesis].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1991, Volume: 18, Issue:4

    Topics: Adult; Aged; Alprazolam; Antiemetics; Carcinoma, Non-Small-Cell Lung; Cisplatin; Female; Humans; Inf

1991
Antiemetic activity of high-dose methylprednisolone associated with continuous-infusion metoclopramide and oral alprazolam during multiple-day chemotherapy.
    Cancer chemotherapy and pharmacology, 1991, Volume: 28, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alprazolam; Antineoplastic Combined Chemotherapy Protoco

1991

Other Studies

8 other studies available for alprazolam and Vomiting

ArticleYear
Benefits and risks of off-label olanzapine use for symptom management in cancer patients-a case report.
    Annals of palliative medicine, 2023, Volume: 12, Issue:3

    Topics: Adenocarcinoma; Aged; Alprazolam; Anorexia; Antiemetics; Cisplatin; Female; Humans; Male; Middle Age

2023
Efficacy of tropisetron in patients with advanced non-small-cell lung cancer receiving adjuvant chemotherapy with carboplatin and taxanes.
    European journal of cancer care, 2008, Volume: 17, Issue:2

    Topics: Aged; Alprazolam; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinom

2008
Laxative withdrawal and anxiety in bulimia nervosa.
    The International journal of eating disorders, 1995, Volume: 17, Issue:2

    Topics: Adult; Alprazolam; Anxiety; Bulimia; Cathartics; Female; Hospitalization; Humans; Substance Withdraw

1995
[Benzodiazepine withdrawal presenting as pseudo-surgical abdominal pain].
    Annales francaises d'anesthesie et de reanimation, 1997, Volume: 16, Issue:5

    Topics: Abdomen, Acute; Adult; Alprazolam; Anti-Anxiety Agents; Bromazepam; Diagnosis, Differential; Headach

1997
[Does the addition of an anxiolytic drug improve the anti-emetic effectiveness of the steroid and granisetron combination in the prophylaxis of cisplatin-induced vomiting?].
    Orvosi hetilap, 2001, Aug-05, Volume: 142, Issue:31

    Topics: Alprazolam; Anti-Anxiety Agents; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Cispla

2001
Antiemetic efficacy of alprazolam in carboplatin-induced emesis.
    Chemotherapy, 1991, Volume: 37, Issue:5

    Topics: Administration, Oral; Aged; Alprazolam; Carboplatin; Drug Therapy, Combination; Female; Humans; Infu

1991
[A combined anti-emesis therapy of oral prednisolone and alprazolam for cisplatin-induced delayed emesis].
    Gan no rinsho. Japan journal of cancer clinics, 1990, Volume: 36, Issue:8

    Topics: Administration, Oral; Adult; Aged; Alprazolam; Antineoplastic Combined Chemotherapy Protocols; Carci

1990
Alprazolam for phobic nausea and vomiting related to cancer chemotherapy.
    Cancer treatment reports, 1987, Volume: 71, Issue:5

    Topics: Adult; Alprazolam; Antineoplastic Agents; Female; Humans; Male; Nausea; Placebos; Vomiting

1987