alprazolam has been researched along with Premenstrual Syndrome in 20 studies
Alprazolam: A triazolobenzodiazepine compound with antianxiety and sedative-hypnotic actions, that is efficacious in the treatment of PANIC DISORDERS, with or without AGORAPHOBIA, and in generalized ANXIETY DISORDERS. (From AMA Drug Evaluations Annual, 1994, p238)
alprazolam : A member of the class of triazolobenzodiazepines that is 4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine carrying methyl, phenyl and chloro substituents at positions 1, 6 and 8 respectively. Alprazolam is only found in individuals that have taken this drug.
Premenstrual Syndrome: A combination of distressing physical, psychologic, or behavioral changes that occur during the luteal phase of the menstrual cycle. Symptoms of PMS are diverse (such as pain, water-retention, anxiety, cravings, and depression) and they diminish markedly 2 or 3 days after the initiation of menses.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine the effectiveness of oral micronized progesterone, alprazolam, and placebo in premenstrual syndrome (PMS) treatment and the effect of clinical contact on treatment responses." | 9.08 | A double-blind trial of oral progesterone, alprazolam, and placebo in treatment of severe premenstrual syndrome. ( Freeman, EW; Polansky, M; Rickels, K; Sondheimer, SJ, 1995) |
| "We observed no significant differences in the severity of premenstrual symptom ratings during alprazolam administration compared with placebo on any scale except the Beck Depression Inventory Scale." | 9.07 | Alprazolam in the treatment of premenstrual syndrome. A double-blind, placebo-controlled trial. ( Grover, GN; Rubinow, DR; Schmidt, PJ, 1993) |
| "A double-blind, placebo-controlled, randomized multiple crossover study was designed to determine the effectiveness of alprazolam in the treatment of premenstrual syndrome." | 9.06 | Treatment of premenstrual syndrome with alprazolam: results of a double-blind, placebo-controlled, randomized crossover clinical trial. ( Rinehart, JS; Ruddock, VE; Schiff, I; Smith, S, 1987) |
| "Data were drawn from 3 double-blind, randomized, placebo-controlled, published treatment trials: alprazolam for patients with premenstrual syndrome (PMS) and diazepam and lorazepam for patients with generalized anxiety disorder (GAD)." | 5.09 | Prior benzodiazepine exposure and benzodiazepine treatment outcome. ( Freeman, EW; Rickels, K, 2000) |
| "To determine the effectiveness of oral micronized progesterone, alprazolam, and placebo in premenstrual syndrome (PMS) treatment and the effect of clinical contact on treatment responses." | 5.08 | A double-blind trial of oral progesterone, alprazolam, and placebo in treatment of severe premenstrual syndrome. ( Freeman, EW; Polansky, M; Rickels, K; Sondheimer, SJ, 1995) |
| "To determine the efficacy of fluoxetine (10 mg), alprazolam, propanolol and pyridoxine in the treatment of severe premenstrual syndrome (PMS)." | 5.08 | A double-blind trial of four medications to treat severe premenstrual syndrome. ( da Fonseca, AM; Diegoli, CA; Diegoli, MS; Pinotti, JA, 1998) |
| "We observed no significant differences in the severity of premenstrual symptom ratings during alprazolam administration compared with placebo on any scale except the Beck Depression Inventory Scale." | 5.07 | Alprazolam in the treatment of premenstrual syndrome. A double-blind, placebo-controlled trial. ( Grover, GN; Rubinow, DR; Schmidt, PJ, 1993) |
| "A double-blind, placebo-controlled, randomized multiple crossover study was designed to determine the effectiveness of alprazolam in the treatment of premenstrual syndrome." | 5.06 | Treatment of premenstrual syndrome with alprazolam: results of a double-blind, placebo-controlled, randomized crossover clinical trial. ( Rinehart, JS; Ruddock, VE; Schiff, I; Smith, S, 1987) |
| "Alprazolam is a benzodiazepine derivative that is currently used in the treatment of generalized anxiety, panic attacks with or without agoraphobia, and depression." | 4.82 | Clinical pharmacology, clinical efficacy, and behavioral toxicity of alprazolam: a review of the literature. ( Verster, JC; Volkerts, ER, 2004) |
| "Alprazolam was found to be superior to placebo." | 2.67 | Treatment of premenstrual dysphoria with alprazolam. A controlled study. ( Endicott, J; Harrison, WM; Nee, J, 1990) |
| " Efficacy has been reported with both continuous dosing (all cycle) and intermittent or luteal phase dosing (from ovulation to menses)." | 2.48 | Psychotropic medications and other non-hormonal treatments for premenstrual disorders. ( Pearlstein, T, 2012) |
| "Three categories of treatments for premenstrual syndrome (PMS) have been proposed: those designed to correct the cause of the disorder; those designed for symptom relief; and those aimed at eliminating the menstrual cycle." | 2.38 | Problems in the treatment of premenstrual syndrome. ( Garfinkel, PE; Robinson, GE, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (15.00) | 18.7374 |
| 1990's | 12 (60.00) | 18.2507 |
| 2000's | 4 (20.00) | 29.6817 |
| 2010's | 1 (5.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pearlstein, T | 1 |
| Vleck, JP | 1 |
| Safranek, SM | 1 |
| Verster, JC | 1 |
| Volkerts, ER | 1 |
| Kroll, R | 1 |
| Rapkin, AJ | 1 |
| Freinhar, JP | 1 |
| van Leusden, HA | 1 |
| Freeman, EW | 3 |
| Rickels, K | 3 |
| Sondheimer, SJ | 1 |
| Polansky, M | 1 |
| Berger, CP | 1 |
| Presser, B | 1 |
| Schmidt, PJ | 1 |
| Grover, GN | 1 |
| Rubinow, DR | 1 |
| Diegoli, MS | 1 |
| da Fonseca, AM | 1 |
| Diegoli, CA | 1 |
| Pinotti, JA | 1 |
| Evans, SM | 2 |
| Haney, M | 1 |
| Levin, FR | 1 |
| Foltin, RW | 2 |
| Fischman, MW | 2 |
| Michener, W | 1 |
| Rozin, P | 1 |
| Freeman, E | 1 |
| Gale, L | 1 |
| Robinson, GE | 1 |
| Garfinkel, PE | 1 |
| Abraham, GE | 1 |
| Hargrove, JT | 1 |
| Harrison, WM | 2 |
| Endicott, J | 2 |
| Nee, J | 1 |
| Smith, S | 1 |
| Rinehart, JS | 1 |
| Ruddock, VE | 1 |
| Schiff, I | 1 |
| Rabkin, JG | 1 |
| Nee, JC | 1 |
| Sandberg, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Multicentre, Prospective, Open-label, Non-comparative Study to Evaluate Menstrual Bleeding Typology, Tolerability, and Compliance During a Monophasic Hormonal Contraceptive Treatment With Norgestimate + Ethinylestradiol in Italy.[NCT06067256] | Phase 4 | 228 participants (Anticipated) | Interventional | 2023-07-20 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for alprazolam and Premenstrual Syndrome
| Article | Year |
|---|---|
Psychotropic medications and other non-hormonal treatments for premenstrual disorders.
Topics: Alprazolam; Anti-Anxiety Agents; Antidepressive Agents; Calcium Compounds; Cognitive Behavioral Ther | 2012 |
Clinical inquiries. What medications are effective for treating symptoms of premenstrual syndrome (PMS)?
Topics: Alprazolam; Anti-Anxiety Agents; Calcium; Estrogen Antagonists; Female; Humans; Premenstrual Syndrom | 2002 |
Clinical pharmacology, clinical efficacy, and behavioral toxicity of alprazolam: a review of the literature.
Topics: Alprazolam; Animals; Anti-Anxiety Agents; Anxiety Disorders; Automobile Driving; Behavior; Clinical | 2004 |
Treatment of premenstrual disorders.
Topics: Alprazolam; Androstenes; Cognitive Behavioral Therapy; Contraceptives, Oral; Exercise; Female; Gonad | 2006 |
Problems in the treatment of premenstrual syndrome.
Topics: Alprazolam; Combined Modality Therapy; Female; Humans; Premenstrual Syndrome | 1990 |
12 trials available for alprazolam and Premenstrual Syndrome
| Article | Year |
|---|---|
A double-blind trial of oral progesterone, alprazolam, and placebo in treatment of severe premenstrual syndrome.
Topics: Administration, Oral; Adult; Alprazolam; Analysis of Variance; Double-Blind Method; Drug Administrat | 1995 |
Alprazolam in the treatment of two subsamples of patients with late luteal phase dysphoric disorder: a double-blind, placebo-controlled crossover study.
Topics: Adult; Alprazolam; Analysis of Variance; Double-Blind Method; Female; Follicular Phase; Humans; Lute | 1994 |
Alprazolam in the treatment of premenstrual syndrome. A double-blind, placebo-controlled trial.
Topics: Adult; Alprazolam; Anxiety; Depression; Dose-Response Relationship, Drug; Double-Blind Method; Drug | 1993 |
A double-blind trial of four medications to treat severe premenstrual syndrome.
Topics: Alprazolam; Anti-Anxiety Agents; Double-Blind Method; Female; Fluoxetine; Humans; Premenstrual Syndr | 1998 |
Mood and performance changes in women with premenstrual dysphoric disorder: acute effects of alprazolam.
Topics: Adult; Affect; Alprazolam; Anti-Anxiety Agents; Dose-Response Relationship, Drug; Double-Blind Metho | 1998 |
Food "cravings" and the acute effects of alprazolam on food intake in women with premenstrual dysphoric disorder.
Topics: Adult; Alprazolam; Anti-Anxiety Agents; Dietary Fats; Eating; Feeding and Eating Disorders; Female; | 1999 |
Characteristics of placebo responses in medical treatment of premenstrual syndrome.
Topics: Adolescent; Adult; Alprazolam; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up | 1999 |
The role of low progesterone and tension as triggers of perimenstrual chocolate and sweets craving: some negative experimental evidence.
Topics: Adult; Alprazolam; Analysis of Variance; Anti-Anxiety Agents; Anxiety; Appetite; Behavior, Addictive | 1999 |
Prior benzodiazepine exposure and benzodiazepine treatment outcome.
Topics: Alprazolam; Anxiety Disorders; Benzodiazepines; Diazepam; Dose-Response Relationship, Drug; Double-B | 2000 |
Treatment of premenstrual dysphoria with alprazolam. A controlled study.
Topics: Adolescent; Adult; Alprazolam; Attitude to Health; Female; Humans; Middle Aged; Outcome and Process | 1990 |
Treatment of premenstrual syndrome with alprazolam: results of a double-blind, placebo-controlled, randomized crossover clinical trial.
Topics: Adult; Alprazolam; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Premenstrual Syndr | 1987 |
Treatment of premenstrual dysphoria with alprazolam and placebo.
Topics: Adolescent; Adult; Alprazolam; Female; Humans; Middle Aged; Premenstrual Syndrome | 1987 |
3 other studies available for alprazolam and Premenstrual Syndrome
| Article | Year |
|---|---|
Alprazolam and premenstrual syndrome.
Topics: Adult; Alprazolam; Anti-Anxiety Agents; Benzodiazepines; Female; Humans; Premenstrual Syndrome | 1984 |
Premenstrual syndrome no progesterone; premenstrual dysphoric disorder no serotonin deficiency.
Topics: Affect; Alprazolam; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Female; Fluoxetin | 1995 |
Diagnosis and treatment of premenstrual syndrome.
Topics: Alprazolam; Female; Humans; Premenstrual Syndrome | 1990 |