alprazolam has been researched along with Pregnancy in 19 studies
Alprazolam: A triazolobenzodiazepine compound with antianxiety and sedative-hypnotic actions, that is efficacious in the treatment of PANIC DISORDERS, with or without AGORAPHOBIA, and in generalized ANXIETY DISORDERS. (From AMA Drug Evaluations Annual, 1994, p238)
alprazolam : A member of the class of triazolobenzodiazepines that is 4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine carrying methyl, phenyl and chloro substituents at positions 1, 6 and 8 respectively. Alprazolam is only found in individuals that have taken this drug.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The newborn of a mother reporting alprazolam use during pregnancy presented with respiratory distress and clinical features consistent with neonatal withdrawal syndrome or neonatal sepsis of vertical transmission." | 7.74 | Confirmation of gestational exposure to alprazolam by analysis of biological matrices in a newborn with neonatal sepsis. ( García-Algar, O; López-Vílchez, MA; Martín, I; Mur, A; Pacifici, R; Pellegrini, M; Pichini, S; Rossi, S, 2007) |
| "To study the association between nitrazepam, medazepam, tofisopam, alprazolum and clonazepam treatments during pregnancy and prevalence of different congenital abnormalities (CAs)." | 7.71 | A population-based case-control teratologic study of nitrazepam, medazepam, tofisopam, alprazolum and clonazepam treatment during pregnancy. ( Czeizel, AE; Eros, E; Olsen, J; Rockenbauer, M; Sorensen, HT, 2002) |
| " In this study, the association between NAS and plasma alprazolam concentration was examined using the measured neonatal concentrations in the time series as well as simulated plasma concentrations of pregnant woman and neonate by physiologically based pharmacokinetic (PBPK) modeling." | 5.51 | Pharmacokinetic assessment of alprazolam-induced neonatal abstinence syndrome using physiologically based pharmacokinetic model. ( Fujioka, K; Fukushima, S; Hashimoto, M; Iijima, K; Mishima, Y; Yamakawa, K; Yamamoto, K; Yano, I, 2019) |
| "The use of benzodiazepines (BZDs) during pregnancy, especially alprazolam, is common and its impact on the fetal neural tissue is not known." | 4.12 | Prenatal effects of alprazolam treatment on the immature cerebellum of rats. ( Botelho, FV; Hirano, LQL; Mascarenhas, FNADP; Menezes-Reis, LT; Ribeiro, DL; Silva, NF; Vieira, LG; Zanon, RG, 2022) |
| "The newborn of a mother reporting alprazolam use during pregnancy presented with respiratory distress and clinical features consistent with neonatal withdrawal syndrome or neonatal sepsis of vertical transmission." | 3.74 | Confirmation of gestational exposure to alprazolam by analysis of biological matrices in a newborn with neonatal sepsis. ( García-Algar, O; López-Vílchez, MA; Martín, I; Mur, A; Pacifici, R; Pellegrini, M; Pichini, S; Rossi, S, 2007) |
| "Mice offspring that were exposed prenatally to alprazolam demonstrated more individual rather than group activities, avoidance of open areas, and aggression in males." | 3.72 | Effects from prenatal exposure to alprazolam on the social behavior of mice offspring. ( Christensen, HD; Gonzalez, CL; Rayburn, WF, 2003) |
| "To study the association between nitrazepam, medazepam, tofisopam, alprazolum and clonazepam treatments during pregnancy and prevalence of different congenital abnormalities (CAs)." | 3.71 | A population-based case-control teratologic study of nitrazepam, medazepam, tofisopam, alprazolum and clonazepam treatment during pregnancy. ( Czeizel, AE; Eros, E; Olsen, J; Rockenbauer, M; Sorensen, HT, 2002) |
| "To assess prospectively pregnancy outcome associated with first-trimester exposure to alprazolam in order to monitor for early signals of potential drug-related risk to the fetus." | 3.68 | First-trimester exposure to alprazolam. ( Schirmer, RG; St Clair, SM, 1992) |
| "Alprazolam was administered orally ten days before mating and during the gestational period." | 1.91 | Alterations in the dentate gyrus of the offspring of rats treated with alprazolam during gestation. ( Mascarenhas, FNADP; Ribeiro, DL; Silva, NF; Zanon, RG, 2023) |
| " In this study, the association between NAS and plasma alprazolam concentration was examined using the measured neonatal concentrations in the time series as well as simulated plasma concentrations of pregnant woman and neonate by physiologically based pharmacokinetic (PBPK) modeling." | 1.51 | Pharmacokinetic assessment of alprazolam-induced neonatal abstinence syndrome using physiologically based pharmacokinetic model. ( Fujioka, K; Fukushima, S; Hashimoto, M; Iijima, K; Mishima, Y; Yamakawa, K; Yamamoto, K; Yano, I, 2019) |
| "Alprazolam exposure was associated with more aggression among C3H/He and C57BL/6 male offspring (P <." | 1.31 | Neurobehavior effects in four strains of mice offspring exposed prenatally to alprazolam. ( Christensen, HD; Gold, KM; Gonzalez, CL; Rayburn, WF, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (10.53) | 18.7374 |
| 1990's | 7 (36.84) | 18.2507 |
| 2000's | 6 (31.58) | 29.6817 |
| 2010's | 2 (10.53) | 24.3611 |
| 2020's | 2 (10.53) | 2.80 |
| Authors | Studies |
|---|---|
| Mascarenhas, FNADP | 2 |
| Silva, NF | 2 |
| Menezes-Reis, LT | 1 |
| Vieira, LG | 1 |
| Hirano, LQL | 1 |
| Botelho, FV | 1 |
| Ribeiro, DL | 2 |
| Zanon, RG | 2 |
| Yamamoto, K | 1 |
| Fukushima, S | 1 |
| Mishima, Y | 1 |
| Hashimoto, M | 1 |
| Yamakawa, K | 1 |
| Fujioka, K | 1 |
| Iijima, K | 1 |
| Yano, I | 1 |
| Mialon, O | 1 |
| Delotte, J | 1 |
| Lehert, P | 1 |
| Donzeau, M | 1 |
| Drici, M | 1 |
| Isnard, V | 1 |
| Bongain, A | 1 |
| Cannizzaro, C | 4 |
| Martire, M | 1 |
| Steardo, L | 1 |
| Cannizzaro, E | 4 |
| Gagliano, M | 4 |
| Mineo, A | 3 |
| Provenzano, G | 1 |
| Rayburn, WF | 2 |
| Christensen, HD | 2 |
| Gold, KM | 1 |
| Gonzalez, CL | 2 |
| Jaiswal, AK | 1 |
| García-Algar, O | 1 |
| López-Vílchez, MA | 1 |
| Martín, I | 1 |
| Mur, A | 1 |
| Pellegrini, M | 1 |
| Pacifici, R | 1 |
| Rossi, S | 1 |
| Pichini, S | 1 |
| Talmud, J | 1 |
| Straughan, JL | 1 |
| Robins, AH | 1 |
| Sabatino, M | 1 |
| Cannizzaro, G | 1 |
| Vendittelli, F | 1 |
| Alain, J | 1 |
| Nouaille, Y | 1 |
| Brosset, A | 1 |
| Tabaste, JL | 1 |
| Shader, RI | 1 |
| Mangiapane, N | 1 |
| Eros, E | 1 |
| Czeizel, AE | 1 |
| Rockenbauer, M | 1 |
| Sorensen, HT | 1 |
| Olsen, J | 1 |
| St Clair, SM | 1 |
| Schirmer, RG | 1 |
| Edwards, JG | 1 |
| Inman, WH | 1 |
| Pearce, GL | 1 |
| Rawson, NS | 1 |
| Pujol Doménech, J | 1 |
19 other studies available for alprazolam and Pregnancy
| Article | Year |
|---|---|
Prenatal effects of alprazolam treatment on the immature cerebellum of rats.
Topics: Alprazolam; Animals; Brain; Cerebellum; Female; Inflammation; Male; Pregnancy; Rats; Rats, Wistar | 2022 |
Alterations in the dentate gyrus of the offspring of rats treated with alprazolam during gestation.
Topics: Alprazolam; Animals; Body Weight; Cell Proliferation; Cell Size; Dentate Gyrus; Female; Lipid Peroxi | 2023 |
Pharmacokinetic assessment of alprazolam-induced neonatal abstinence syndrome using physiologically based pharmacokinetic model.
Topics: Alprazolam; Female; Humans; Hypnotics and Sedatives; Models, Biological; Neonatal Abstinence Syndrom | 2019 |
[Comparison between two analgesic protocols on IVF success rates].
Topics: Acetaminophen; Adult; Alprazolam; Analgesia; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Em | 2011 |
Prenatal exposure to diazepam and alprazolam, but not to zolpidem, affects behavioural stress reactivity in handling-naïve and handling-habituated adult male rat progeny.
Topics: Age Factors; Alprazolam; Animals; Anti-Anxiety Agents; Behavior, Animal; Convulsants; Diazepam; Expl | 2002 |
Neurobehavior effects in four strains of mice offspring exposed prenatally to alprazolam.
Topics: Aggression; Alprazolam; Animals; Anti-Anxiety Agents; Anxiety, Separation; Behavior, Animal; Female; | 2002 |
Effect of prenatal alprazolam exposure on anxiety patterns in rat offspring.
Topics: Alprazolam; Animals; Anti-Anxiety Agents; Anxiety Disorders; Behavior, Animal; Exploratory Behavior; | 2002 |
Effects from prenatal exposure to alprazolam on the social behavior of mice offspring.
Topics: Aggression; Alprazolam; Animals; Anti-Anxiety Agents; Behavior, Animal; Escape Reaction; Female; Mal | 2003 |
Confirmation of gestational exposure to alprazolam by analysis of biological matrices in a newborn with neonatal sepsis.
Topics: Adult; Alprazolam; Anti-Anxiety Agents; Diagnosis, Differential; Female; Fetal Blood; Hair; Humans; | 2007 |
Alprazolam--a new triazolobenzodiazepine.
Topics: Alprazolam; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Depressive Disorder; Drug Inter | 1984 |
Effects of desipramine and alprazolam on forced swimming behaviour of adult rats exposed to prenatal diazepam.
Topics: Alprazolam; Animals; Behavior, Animal; Depression; Desipramine; Diazepam; Electroencephalography; El | 1995 |
A case of lipomeningocele reported with fluoxetine (and alprazolam, vitamins B1 and B6, heptaminol) prescribed during pregnancy.
Topics: Adult; Alprazolam; Depression; Drug Therapy, Combination; Female; Fluoxetine; Heptaminol; Humans; In | 1995 |
Is there anything new on the use of psychotropic drugs during pregnancy?
Topics: Abnormalities, Drug-Induced; Adult; Alprazolam; Anti-Anxiety Agents; Female; Humans; Infant, Newborn | 1994 |
Behavioural responsiveness to picrotoxin and desipramine in adult rats prenatally exposed to different benzodiazepine receptor agonists.
Topics: Adrenergic Uptake Inhibitors; Alprazolam; Animals; Behavior, Animal; Desipramine; Diazepam; Female; | 1995 |
Locomotor and antidepressant-like effects of 5-HT(1A) agonist LY 228729 in prenatally benzodiazepine-exposed rats.
Topics: Alprazolam; Animals; Anti-Anxiety Agents; Antidepressive Agents; Depressive Disorder; Diazepam; Ergo | 1998 |
A population-based case-control teratologic study of nitrazepam, medazepam, tofisopam, alprazolum and clonazepam treatment during pregnancy.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Alprazolam; Anti-Anxiety Agents; Antico | 2002 |
First-trimester exposure to alprazolam.
Topics: Abnormalities, Drug-Induced; Alprazolam; Female; Follow-Up Studies; Humans; Pregnancy; Pregnancy Out | 1992 |
Prescription-event monitoring of 10,895 patients treated with alprazolam.
Topics: Adult; Aged; Alprazolam; Anxiety Disorders; Depressive Disorder; Drug Overdose; Female; Follow-Up St | 1991 |
[Panic crisis in a pregnant hyperthyroid woman].
Topics: Adult; Alprazolam; Antithyroid Agents; Anxiety; Fear; Female; Humans; Hyperthyroidism; Monoamine Oxi | 1988 |