Page last updated: 2024-10-22

alprazolam and Postoperative Complications

alprazolam has been researched along with Postoperative Complications in 8 studies

Alprazolam: A triazolobenzodiazepine compound with antianxiety and sedative-hypnotic actions, that is efficacious in the treatment of PANIC DISORDERS, with or without AGORAPHOBIA, and in generalized ANXIETY DISORDERS. (From AMA Drug Evaluations Annual, 1994, p238)
alprazolam : A member of the class of triazolobenzodiazepines that is 4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine carrying methyl, phenyl and chloro substituents at positions 1, 6 and 8 respectively. Alprazolam is only found in individuals that have taken this drug.

Postoperative Complications: Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.

Research Excerpts

ExcerptRelevanceReference
"The effectiveness of alprazolam in treating symptoms of anxiety and depression in 60 patients undergoing coronary bypass surgery was assessed in a double-blind, placebo-controlled study."9.06Alprazolam treatment of postcoronary bypass anxiety and depression. ( Fleece, L; Folks, DG; Freeman, AM; Hall, KR; Karp, RB; Kirklin, JK; McGiffin, DC; Pacifico, AD; Sokol, RS; Zorn, GL, 1986)
"To assess the effects of melatonin on preoperative and postoperative anxiety compared to placebo or benzodiazepines."9.05Melatonin for preoperative and postoperative anxiety in adults. ( Madsen, BK; Møller, AM; Rosenberg, J; Zetner, D, 2020)
"To evaluate the effect of preoperative Alprazolam on complications of phacoemulsification cataract surgery, duration of surgery and early reoperation rate."8.31Using Alprazolam before phacoemulsification cataract surgery reduces complications and duration of the surgery. ( Kaderli, A; Kaderli, ST; Karalezli, A; Korkmaz, S; Sul, S, 2023)
"The effectiveness of alprazolam in treating symptoms of anxiety and depression in 60 patients undergoing coronary bypass surgery was assessed in a double-blind, placebo-controlled study."5.06Alprazolam treatment of postcoronary bypass anxiety and depression. ( Fleece, L; Folks, DG; Freeman, AM; Hall, KR; Karp, RB; Kirklin, JK; McGiffin, DC; Pacifico, AD; Sokol, RS; Zorn, GL, 1986)
"To assess the effects of melatonin on preoperative and postoperative anxiety compared to placebo or benzodiazepines."5.05Melatonin for preoperative and postoperative anxiety in adults. ( Madsen, BK; Møller, AM; Rosenberg, J; Zetner, D, 2020)
"To evaluate the effect of preoperative Alprazolam on complications of phacoemulsification cataract surgery, duration of surgery and early reoperation rate."4.31Using Alprazolam before phacoemulsification cataract surgery reduces complications and duration of the surgery. ( Kaderli, A; Kaderli, ST; Karalezli, A; Korkmaz, S; Sul, S, 2023)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's4 (50.00)18.2507
2000's1 (12.50)29.6817
2010's0 (0.00)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Korkmaz, S1
Kaderli, A1
Kaderli, ST1
Sul, S1
Karalezli, A1
Madsen, BK1
Zetner, D1
Møller, AM1
Rosenberg, J1
al-Hmoud, N1
Muchada, R1
Lucchesie, G1
Freda, JJ1
Bush, HL1
Barie, PS1
Freiberger, JJ1
Marsicano, TH1
Tamaki, K1
Nishida, M1
Hiraide, H1
Tamakuma, S1
Freeman, AM1
Fleece, L1
Folks, DG1
Sokol, RS1
Hall, KR1
Pacifico, AD1
McGiffin, DC1
Kirklin, JK1
Zorn, GL1
Karp, RB1

Clinical Trials (6)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Premedication With Melatonin vs. Placebo in Patients Undergoing Interventional Pain Procedure[NCT02415309]Phase 325 participants (Actual)Interventional2016-07-31Completed
SurgerySMART: Studying Melatonin and Recovery in Teens[NCT06093477]40 participants (Anticipated)Interventional2024-07-31Not yet recruiting
Anxiolytic and Analgesic Effects of Melatonin: A Randomized, Double-blinded, Placebo-controlled Clinical Study[NCT02386319]Phase 336 participants (Actual)Interventional2016-08-31Completed
Perioperative Analgesic and Anxiolytic Effect of Melatonin in Patients Undergoing Lumbar Laminectomy[NCT01126294]84 participants (Anticipated)Interventional2010-04-30Recruiting
Use of Melatonin for Prevention of POCD After TURP Surgery Under Spinal Anesthesia for Elderly Patients[NCT03966950]104 participants (Anticipated)Interventional2017-06-26Recruiting
The Effect of MElatonin on Depression, Anxiety, CIrcadian and Sleep Disturbances in Patients After Acute Myocardial Syndrome[NCT02451293]Phase 2/Phase 3252 participants (Actual)Interventional2016-01-18Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Preoperative Anxiety

"The State scale of the State-Trait Anxiety Inventory (STAI). Construct: Current level of anxiety. Scale range: 20-40 (higher scores indicate higher level of current anxiety) Scores are calculated according to the STAI scoring manual by adding point from each item (possible point for each item is 1-4)." (NCT02386319)
Timeframe: 60 minutes preoperative

Interventionscore on a scale (Median)
Melatonin27
Placebo28

Reviews

1 review available for alprazolam and Postoperative Complications

ArticleYear
Melatonin for preoperative and postoperative anxiety in adults.
    The Cochrane database of systematic reviews, 2020, 12-08, Volume: 12

    Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi

2020
Melatonin for preoperative and postoperative anxiety in adults.
    The Cochrane database of systematic reviews, 2020, 12-08, Volume: 12

    Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi

2020
Melatonin for preoperative and postoperative anxiety in adults.
    The Cochrane database of systematic reviews, 2020, 12-08, Volume: 12

    Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi

2020
Melatonin for preoperative and postoperative anxiety in adults.
    The Cochrane database of systematic reviews, 2020, 12-08, Volume: 12

    Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi

2020
Melatonin for preoperative and postoperative anxiety in adults.
    The Cochrane database of systematic reviews, 2020, 12-08, Volume: 12

    Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi

2020
Melatonin for preoperative and postoperative anxiety in adults.
    The Cochrane database of systematic reviews, 2020, 12-08, Volume: 12

    Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi

2020
Melatonin for preoperative and postoperative anxiety in adults.
    The Cochrane database of systematic reviews, 2020, 12-08, Volume: 12

    Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi

2020
Melatonin for preoperative and postoperative anxiety in adults.
    The Cochrane database of systematic reviews, 2020, 12-08, Volume: 12

    Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi

2020
Melatonin for preoperative and postoperative anxiety in adults.
    The Cochrane database of systematic reviews, 2020, 12-08, Volume: 12

    Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi

2020
Melatonin for preoperative and postoperative anxiety in adults.
    The Cochrane database of systematic reviews, 2020, 12-08, Volume: 12

    Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi

2020
Melatonin for preoperative and postoperative anxiety in adults.
    The Cochrane database of systematic reviews, 2020, 12-08, Volume: 12

    Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi

2020
Melatonin for preoperative and postoperative anxiety in adults.
    The Cochrane database of systematic reviews, 2020, 12-08, Volume: 12

    Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi

2020
Melatonin for preoperative and postoperative anxiety in adults.
    The Cochrane database of systematic reviews, 2020, 12-08, Volume: 12

    Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi

2020
Melatonin for preoperative and postoperative anxiety in adults.
    The Cochrane database of systematic reviews, 2020, 12-08, Volume: 12

    Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi

2020
Melatonin for preoperative and postoperative anxiety in adults.
    The Cochrane database of systematic reviews, 2020, 12-08, Volume: 12

    Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi

2020
Melatonin for preoperative and postoperative anxiety in adults.
    The Cochrane database of systematic reviews, 2020, 12-08, Volume: 12

    Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi

2020
Melatonin for preoperative and postoperative anxiety in adults.
    The Cochrane database of systematic reviews, 2020, 12-08, Volume: 12

    Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi

2020
Melatonin for preoperative and postoperative anxiety in adults.
    The Cochrane database of systematic reviews, 2020, 12-08, Volume: 12

    Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi

2020
Melatonin for preoperative and postoperative anxiety in adults.
    The Cochrane database of systematic reviews, 2020, 12-08, Volume: 12

    Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi

2020
Melatonin for preoperative and postoperative anxiety in adults.
    The Cochrane database of systematic reviews, 2020, 12-08, Volume: 12

    Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi

2020
Melatonin for preoperative and postoperative anxiety in adults.
    The Cochrane database of systematic reviews, 2020, 12-08, Volume: 12

    Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi

2020
Melatonin for preoperative and postoperative anxiety in adults.
    The Cochrane database of systematic reviews, 2020, 12-08, Volume: 12

    Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi

2020
Melatonin for preoperative and postoperative anxiety in adults.
    The Cochrane database of systematic reviews, 2020, 12-08, Volume: 12

    Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi

2020
Melatonin for preoperative and postoperative anxiety in adults.
    The Cochrane database of systematic reviews, 2020, 12-08, Volume: 12

    Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi

2020
Melatonin for preoperative and postoperative anxiety in adults.
    The Cochrane database of systematic reviews, 2020, 12-08, Volume: 12

    Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi

2020
Melatonin for preoperative and postoperative anxiety in adults.
    The Cochrane database of systematic reviews, 2020, 12-08, Volume: 12

    Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi

2020
Melatonin for preoperative and postoperative anxiety in adults.
    The Cochrane database of systematic reviews, 2020, 12-08, Volume: 12

    Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi

2020
Melatonin for preoperative and postoperative anxiety in adults.
    The Cochrane database of systematic reviews, 2020, 12-08, Volume: 12

    Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi

2020
Melatonin for preoperative and postoperative anxiety in adults.
    The Cochrane database of systematic reviews, 2020, 12-08, Volume: 12

    Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi

2020
Melatonin for preoperative and postoperative anxiety in adults.
    The Cochrane database of systematic reviews, 2020, 12-08, Volume: 12

    Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi

2020
Melatonin for preoperative and postoperative anxiety in adults.
    The Cochrane database of systematic reviews, 2020, 12-08, Volume: 12

    Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi

2020
Melatonin for preoperative and postoperative anxiety in adults.
    The Cochrane database of systematic reviews, 2020, 12-08, Volume: 12

    Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi

2020
Melatonin for preoperative and postoperative anxiety in adults.
    The Cochrane database of systematic reviews, 2020, 12-08, Volume: 12

    Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi

2020
Melatonin for preoperative and postoperative anxiety in adults.
    The Cochrane database of systematic reviews, 2020, 12-08, Volume: 12

    Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi

2020
Melatonin for preoperative and postoperative anxiety in adults.
    The Cochrane database of systematic reviews, 2020, 12-08, Volume: 12

    Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi

2020
Melatonin for preoperative and postoperative anxiety in adults.
    The Cochrane database of systematic reviews, 2020, 12-08, Volume: 12

    Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi

2020

Trials

1 trial available for alprazolam and Postoperative Complications

ArticleYear
Alprazolam treatment of postcoronary bypass anxiety and depression.
    Journal of clinical psychopharmacology, 1986, Volume: 6, Issue:1

    Topics: Adult; Aged; Alprazolam; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Benzodiazepines; Clini

1986

Other Studies

6 other studies available for alprazolam and Postoperative Complications

ArticleYear
Using Alprazolam before phacoemulsification cataract surgery reduces complications and duration of the surgery.
    International ophthalmology, 2023, Volume: 43, Issue:7

    Topics: Alprazolam; Cataract; Humans; Lens Capsule, Crystalline; Lenses, Intraocular; Phacoemulsification; P

2023
Koro-like syndrome in a Jordanian male.
    Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit, 1999, Volume: 5, Issue:3

    Topics: Adult; Alprazolam; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Behavior Therapy; Combined

1999
[Carotid endarterectomy under remifentanil].
    Revista espanola de anestesiologia y reanimacion, 2001, Volume: 48, Issue:10

    Topics: Aged; Aged, 80 and over; Alprazolam; Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetic

2001
Alprazolam withdrawal in a critically ill patient.
    Critical care medicine, 1992, Volume: 20, Issue:4

    Topics: Aged; Akathisia, Drug-Induced; Alprazolam; Aorta, Abdominal; Aortic Aneurysm; Critical Illness; Huma

1992
Alprazolam withdrawal presenting as delirium after cardiac surgery.
    Journal of cardiothoracic and vascular anesthesia, 1991, Volume: 5, Issue:2

    Topics: Alprazolam; Delirium; Humans; Male; Middle Aged; Myocardial Revascularization; Postoperative Complic

1991
[Alprazolam for patients with psychotic symptoms or autonomic imbalance symptoms after breast cancer surgery].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1991, Volume: 18, Issue:8

    Topics: Adult; Aged; Alprazolam; Autonomic Nervous System Diseases; Breast Neoplasms; Female; Humans; Mastec

1991