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alprazolam and Panic Disorder

alprazolam has been researched along with Panic Disorder in 190 studies

Alprazolam: A triazolobenzodiazepine compound with antianxiety and sedative-hypnotic actions, that is efficacious in the treatment of PANIC DISORDERS, with or without AGORAPHOBIA, and in generalized ANXIETY DISORDERS. (From AMA Drug Evaluations Annual, 1994, p238)
alprazolam : A member of the class of triazolobenzodiazepines that is 4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine carrying methyl, phenyl and chloro substituents at positions 1, 6 and 8 respectively. Alprazolam is only found in individuals that have taken this drug.

Panic Disorder: A type of anxiety disorder characterized by unexpected panic attacks that last minutes or, rarely, hours. Panic attacks begin with intense apprehension, fear or terror and, often, a feeling of impending doom. Symptoms experienced during a panic attack include dyspnea or sensations of being smothered; dizziness, loss of balance or faintness; choking sensations; palpitations or accelerated heart rate; shakiness; sweating; nausea or other form of abdominal distress; depersonalization or derealization; paresthesias; hot flashes or chills; chest discomfort or pain; fear of dying and fear of not being in control of oneself or going crazy. Agoraphobia may also develop. Similar to other anxiety disorders, it may be inherited as an autosomal dominant trait.

Research Excerpts

ExcerptRelevanceReference
"The objective of this study was to ascertain the relationship of alprazolam plasma levels and an anxiety-prone cognitive style to the characteristics and severity of early withdrawal after abrupt discontinuation of alprazolam in 26 patients with panic disorder."9.12Abrupt discontinuation of alprazolam and cognitive style in patients with panic disorder: early effects on mood, performance, and vital signs. ( Antal, EJ; Barnhill, J; Javaid, JI; Matuzas, W; Qualls, C; Starcevic, V; Uhlenhuth, EH, 2006)
"Anxiolytic therapy with the benzodiazepine alprazolam is an established therapy in patients with panic disorder."9.12Anxiolytic therapy with alprazolam increases muscle sympathetic activity in patients with panic disorders. ( Béchir, M; Binggeli, C; Büchi, S; Buddeberg, C; Caduff, C; Chenevard, R; Lüscher, TF; Noll, G; Schwegler, K, 2007)
"This study compares the speed of onset of action of the extended release (XR) formulation of alprazolam with that of the compressed tablet (CT) formulation in a sample of outpatients with DSM-IV panic disorder."9.12The speed of onset of action of alprazolam-XR compared to alprazolam-CT in panic disorder. ( Raj, BA; Sheehan, DV; Sheehan, KH, 2007)
"In 123 panic disorder patients undergoing gradual tapered discontinuation of alprazolam in conjunction with pre-treatment with carbamazepine or placebo, the relationship between measures of 'symptom sensitivity' and 'harm avoidance', and severity of withdrawal symptoms measured as peak severity of symptoms, time before taper needed to be slowed due to symptoms, and ability to complete taper, was examined."9.10Personality and symptom sensitivity predictors of alprazolam withdrawal in panic disorder. ( Ballenger, J; Bell, J; Bystrisky, A; Corrigan, MH; Pollack, M; Rosenbaum, J; Roy-Byrne, P; Rush, AJ; Russo, J; Stewart, R; Stolk, J, 2003)
" Results showed that 75% of the Peoria sample and 76% of the Dartmouth sample were able to discontinue alprazolam therapy, remain abstinent of any type of treatment for panic disorder, and maintain their acute-treatment clinical gains over this follow-up period."9.09Cognitive-behavioral therapy helps prevent relapse and recurrence of panic disorder following alprazolam discontinuation: a long-term follow-up of the Peoria and Dartmouth studies. ( Bruce, TJ; Hegel, MT; Spiegel, DA, 1999)
" A previous study with agoraphobia/panic patients found that the BZ alprazolam impaired memory during an 8-week treatment and residual impairments were still manifest several weeks after drug withdrawal (Curran et al."9.09Long-term effects of alprazolam on memory: a 3.5 year follow-up of agoraphobia/panic patients. ( Başoğlu, M; Curran, HV; Kiliç, C; Marks, IM; Noshirvani, H, 1999)
"Our data suggest the comparable efficacy of alprazolam and imipramine in the short-term treatment of older adults with panic disorder."9.09Treatment of panic disorder in older adults: a pilot study comparison of alprazolam, imipramine, and placebo. ( Sheikh, JI; Swales, PJ, 1999)
"The pharmacokinetics and pharmacodynamics of the benzodiazepine alprazolam (1 mg, administered orally) were compared between eight patients with panic disorder and eight age- and sex-matched healthy volunteers."9.09Differences in pharmacodynamics but not pharmacokinetics between subjects with panic disorder and healthy subjects after treatment with a single dose of alprazolam. ( Ehrenberg, BL; Goddard, JE; Greenblatt, DJ; Harmatz, JS; Kaplan, GB; Shader, RI, 2000)
" As part of a placebo-controlled trial of alprazolam-XR (extended release) administered in combination with cognitive-behavioral therapy in patients with panic disorder, a battery of tests was used to measure neuropsychologic function."9.09Absence of neuropsychologic deficits in patients receiving long-term treatment with alprazolam-XR for panic disorder. ( Auerbach, M; Gladsjo, JA; Hahn, T; Haze, A; Judd, LL; McKinney, R; Oliver, T; Rabin, A; Rapaport, MH, 2001)
") and to clonidine (150 micrograms) were measured in 10 outpatients with panic disorder before and after 30 days of 2-2."9.08Alpha 2-adrenergic receptor sensitivity in panic disorder: I. GH response to GHRH and clonidine stimulation in panic disorder. ( Bellodi, L; Brambilla, F; Garberi, A; Nobile, P; Perna, G, 1995)
"The cortisol responses to acute administration of saline and of clonidine (Clon), 150 micrograms IV, were examined in 12 patients with panic disorder and agoraphobia, before and after 32 days of alprazolam therapy (2."9.08Alpha 2-adrenergic receptor sensitivity in panic disorder: II. Cortisol response to clonidine stimulation in panic disorder. ( Arancio, C; Bellodi, L; Brambilla, F; Nobile, P; Perna, G, 1995)
"22 patients with panic disorder (diagnosis according to ICD-10) were treated with alprazolam (monotherapy) in a dose of 1-2,5 mg/daily during 6 weeks."9.08[The efficacy of alprazolam in the therapy of panic disorders]. ( Diukova, GM; Petrova, EP; Smirnov, SV; Tumalaeva, ZN; Vorob'eva, OV, 1995)
"Cerebrospinal fluid (CSF) gamma-aminobutyric acid (GABA) levels were measured in 11 patients with panic disorder (PD) prior to and following 7 months of treatment with alprazolam or imipramine and in six neurological control patients."9.08Cerebrospinal fluid gamma-aminobutyric acid in patients with panic disorder. ( Halonen, T; Jolkkonen, J; Lepola, U; Riekkinen, P; Rimón, R, 1995)
"23 patients with a diagnosis of panic disorder with agoraphobia were randomly assigned to 8 weeks' treatment with alprazolam or placebo."9.08Behavioural aggression in panic disorder after 8 weeks' treatment with alprazolam. ( Bond, AJ; Bruce, MS; Curran, HV; O'Sullivan, G; Shine, P, 1995)
"Alprazolam has proven efficacy as a treatment for panic disorder, but the place of other benzodiazepines is less well established."9.08Diazepam versus alprazolam for the treatment of panic disorder. ( Burrows, GD; Cook, BL; Garvey, MJ; Judd, FK; Marriott, P; Norman, TR; Noyes, R; Reich, JH, 1996)
" The efficacy of alprazolam and placebo in panic disorder with agoraphobia, and the side-effect and adverse effect profiles of both drug groups were measured."9.07Safety and side-effects of alprazolam. Controlled study in agoraphobia with panic disorder. ( Başoğlu, M; Kirby, M; Kuch, K; Marks, IM; Noshirvani, H; O'Sullivan, GH; Swinson, R, 1994)
" Eighty-two agoraphobics with panic disorder were randomly allocated to one of four treatment groups resulting from a combination of two drug treatments (alprazolam or placebo) and two psychological treatments (exposure or relaxation)."9.07Memory functions, alprazolam and exposure therapy: a controlled longitudinal study of agoraphobia with panic disorder. ( Bond, A; Bruce, M; Curran, HV; Lader, M; Lelliot, P; Marks, I; O'Sullivan, G; Shine, P, 1994)
"Pre-treatment predictors of treatment outcome were examined in a group of 144 patients with panic disorder and agoraphobia randomly allocated to alprazolam+exposure (AE), placebo+exposure (PE), alprazolam+relaxation (AR), and placebo+relaxation (PR)."9.07Pre-treatment predictors of treatment outcome in panic disorder and agoraphobia treated with alprazolam and exposure. ( Başoğlu, M; Kuch, K; Marks, IM; Noshirvani, H; O'Sullivan, G; Swinson, RP, 1994)
"In a controlled trial of alprazolam and exposure in 154 patients with panic disorder with agoraphobia, relations between panic, anticipatory anxiety, and phobic avoidance were examined."9.07Relationship of panic, anticipatory anxiety, agoraphobia and global improvement in panic disorder with agoraphobia treated with alprazolam and exposure. ( Başoğlu, M; Kiliç, C; Kuch, K; Marks, IM; Noshirvani, H; O'Sullivan, G; Swinson, RP, 1994)
"Patients with panic disorder plus agoraphobia had 8 weeks of drug treatment (alprazolam or placebo) plus psychological treatment (exposure or relaxation)."9.07Alprazolam and exposure for panic disorder with agoraphobia. Attribution of improvement to medication predicts subsequent relapse. ( Başoğlu, M; Brewin, CR; Kiliç, C; Marks, IM; Swinson, RP, 1994)
"This study was designed to examine the possibility that patients with panic disorder are especially vulnerable to alprazolam withdrawal, as well as to evaluate the efficacy of carbamazepine as adjunctive treatment during alprazolam discontinuation."9.07Alprazolam withdrawal in patients with panic disorder and generalized anxiety disorder: vulnerability and effect of carbamazepine. ( Colin, V; Klein, E; Lenox, RH; Stolk, J, 1994)
"This study examines clinical predictors of outcome for patients with panic disorder and depression in a 16 week, placebo-controlled trial of alprazolam and imipramine (n = 126)."9.07Anxiety psychopathology predictive of outcome in patients with panic disorder and depression treated with imipramine, alprazolam and placebo. ( Deltito, JA; Keller, MB; Leon, A; Otto, MW; Pollack, MH; Rosenbaum, JF; Sachs, GS; Shear, MK, 1994)
"The primary aim of this study was to determine if pretreatment with a single dose of alprazolam reduces anxiety and panic provoked by the inhalation of 35% carbon dioxide (CO2) in patients with panic disorder."9.07Alprazolam blockade of CO2-provoked panic in patients with panic disorder. ( Asnis, GM; Sanderson, WC; Wetzler, S, 1994)
"Date from a panic disorder treatment study with 506 patients, comparing alprazolam and placebo in a double-blind manner for 8 weeks, were analyzed to identify demographic and clinical characteristics of the patients that might predict response to treatment."9.07Predictors of response to alprazolam and placebo in patients with panic disorder. ( Ballenger, JC; Lydiard, RB; Mihalko, D; Noyes, R; Sievers, G; Woodman, CL, 1994)
"The authors investigated whether cognitive behavioral treatment could facilitate discontinuation of alprazolam therapy and maintenance of drug abstinence among panic disorder patients treated with alprazolam doses sufficient to suppress spontaneous panic attacks."9.07Does cognitive behavior therapy assist slow-taper alprazolam discontinuation in panic disorder? ( Bruce, TJ; Gregg, SF; Nuzzarello, A; Spiegel, DA, 1994)
"One hundred ninety-four patients with diagnosis of agoraphobia with panic attacks or panic disorder with limited phobic avoidance underwent a 1-week placebo washout before being randomly assigned to groups receiving 8 weeks of double-blind treatment with either sustained-release alprazolam or placebo."9.07Double-blind, placebo-controlled study of a once-a-day, sustained-release preparation of alprazolam for the treatment of panic disorder. ( Patterson, W; Rickels, K; Rosenthal, M; Schweizer, E, 1993)
"Fifty-five patients with moderate to sever panic disorder were treated for 9 weeks with alprazolam or imipramine and were then, except for one patient who had committed suicide, re-examined after on average 3 years of treatment."9.07Three-year follow-up of patients with panic disorder after short-term treatment with alprazolam and imipramine. ( Lepola, UM; Riekkinen, PJ; Rimón, RH, 1993)
"A series of 237 patients with DSM-III-diagnosed panic disorder, or agoraphobia with panic attacks, received alprazolam as part of the placebo-controlled Cross-National Collaborative Panic Study."9.07Plasma alprazolam concentrations. Relation to efficacy and side effects in the treatment of panic disorder. ( Greenblatt, DJ; Harmatz, JS; Shader, RI, 1993)
" According to logistic regression analysis, the relationships between plasma alprazolam concentration and response, as reflected by number of panic attacks reported, phobia ratings, physicians' and patients' ratings of global improvement, and the emergence of side effects, were significant."9.07Alprazolam plasma concentrations and treatment response in panic disorder and agoraphobia. ( Antal, E; Ballenger, JC; DuPont, R; Lesser, IM; Lydiard, RB; Rubin, RT, 1992)
"The reactivity of 40 panic disorder patients on mental arithmetic, cold pressor, and 5% CO2 inhalation stressors was tested before and after 8 weeks of treatment with imipramine, alprazolam, or placebo."9.07Imipramine and alprazolam effects on stress test reactivity in panic disorder. ( Agras, WS; Ehlers, A; Haddad, JM; Maddock, RJ; Margraf, J; Roth, WT; Taylor, CB, 1992)
"To investigate whether alprazolam (ALP) coprescription early in the imipramine (IMI) treatment of panic disorder would improve overall treatment response to IMI alone, 48 panic disorder patients were randomly assigned to receive either IMI plus placebo or IMI plus ALP for 4-6 weeks, followed by 2 weeks of IMI plus placebo-ALP taper and 2 more weeks of IMI alone."9.07Controlled trial of alprazolam supplementation during imipramine treatment of panic disorder. ( Charney, DS; Heninger, GR; Koleszar, AS; Krystal, JH; Nagy, LM; Woods, SW, 1992)
"A recently reported multinational, 8-week double-blind, placebo-controlled study assessing the efficacy of alprazolam versus placebo in the treatment of panic disorder indicated significant differences favoring alprazolam."9.07A fixed-dose study of alprazolam 2 mg, alprazolam 6 mg, and placebo in panic disorder. ( Ballenger, JC; DuPont, R; Laraia, M; Lesser, IM; Lydiard, RB; Rubin, RT, 1992)
"To investigate the potential impact of increasing prescription rates of alprazolam for the treatment of panic disorder (PD) in Australia through a review of efficacy, tolerability and adverse outcome literature."8.88The role of alprazolam for the treatment of panic disorder in Australia. ( Berk, M; Giorlando, F; Moylan, S; Nordfjærn, T, 2012)
"We performed a meta-analysis of all single- or double-blind, randomized controlled trials comparing alprazolam to another benzodiazepine in the treatment of adult patients meeting the Diagnostic and Statistical Manual of Mental Disorders, Third or Fourth Edition, criteria for panic disorder or agoraphobia with panic attacks."8.87The efficacy and safety of alprazolam versus other benzodiazepines in the treatment of panic disorder. ( Berk, M; Moylan, S; Rogerson, J; Staples, J; Stein, DJ; Ward, SA, 2011)
"Alprazolam was the first pharmacological agent to be approved for the treatment of panic disorder."8.80Efficacy studies of alprazolam in panic disorder. ( Spiegel, DA, 1998)
" Doxapram is an analeptic capable of inducing panic attacks with respiratory symptoms in individuals diagnosed with the disorder; however, its neuroanatomical targets and its effects on experimental animals remain uncharacterized."8.02Intravenous doxapram administration as a potential model of panic attacks in rats. ( Batista, LA; Brianis, RC; Haibara, AS; Lopes, JB; Moreira, FA, 2021)
"We experienced an 11-year-old boy with panic disorder responding remarkably to paroxetine."7.7411-year-old boy with panic disorder responding to paroxetine. ( Matsumoto, H; Tamai, Y, 2007)
"This study investigated an anxiety-prone cognitive style (measured by the Anxious Thoughts and Tendencies Questionnaire, AT&T) as a predictor of the acute response to increasing alprazolam plasma levels in panic disorder."7.74Cognitive style, alprazolam plasma levels, and treatment response in panic disorder. ( Antal, EJ; Barnhill, J; Javaid, JI; Matuzas, W; Qualls, C; Starcevic, V; Uhlenhuth, EH, 2008)
"Escitalopram, the active enantiomer of the selective serotonin reuptake inhibitor (SSRI) citalopram, has effects in animal models for the detection of antidepressant and anxiolytic effect and in patients with major depressive and anxiety disorders."7.73Prediction of anti-panic properties of escitalopram in the dorsal periaqueductal grey model of panic anxiety. ( Hogg, S; Jessa, M; Michan, L, 2006)
" Changes in the plasma cortisol level were reported in a male patient with panic disorder during the period of low-dose alprazolam treatment (mean 0."7.70Decreased plasma cortisol level during alprazolam treatment of panic disorder: a case report. ( Fukuda, M; Hata, A; Hiramatsu, K; Iwanami, A; Kasai, K; Nakagome, K; Takazawa, S, 1998)
"Plasma concentrations of tumor necrosis factor-alpha (TNF-alpha) were measured in 10 outpatients with panic disorder, twice (at a 48-h interval) before and twice on days 30-32 of treatment with alprazolam (2-2."7.70Plasma levels of tumor necrosis factor-alpha in patients with panic disorder: effect of alprazolam therapy. ( Bellodi, L; Brambilla, F; Perna, G, 1999)
"In a previous paper the authors reported survival data for 20 panic disorder patients whose therapeutic doses of alprazolam were tapered by one of two methods: slow, flexible drug taper with supportive medical management or the same taper procedure carried out concurrently with cognitive behavior therapy."7.69Predictors of alprazolam discontinuation with and without cognitive behavior therapy in panic disorder. ( Bruce, TJ; Gregg, SF; Nuzzarello, A; Spiegel, DA, 1995)
"The aim of the current study was to determine the degree to which patients with panic disorder develop tolerance to subjective and physiological effects of benzodiazepine after chronic treatment with alprazolam."7.69Benzodiazepine sensitivity in panic disorder: effects of chronic alprazolam treatment. ( Cowley, DS; Greenblatt, DJ; Hommer, DW; Nemeroff, CB; Radant, A; Ritchie, JC; Roy-Byrne, PP, 1995)
"The authors report on seven consecutive openly treated patients with panic disorder who showed inadequate antipanic responses to treatment regimens including either a tricyclic (TCA) or fluoxetine."7.69Augmentation strategies with tricyclic or fluoxetine treatment in seven partially responsive panic disorder patients. ( Coplan, JD; Gorman, JM; Papp, LA; Tiffon, L, 1994)
"Thirty-six patients with panic disorder (PD) and 35 patients with generalized anxiety disorder (GAD) participated in an open alprazolam treatment phase that preceded controlled withdrawal from alprazolam."7.69Clinical similarity and biological diversity in the response to alprazolam in patients with panic disorder and generalized anxiety disorder. ( Colin, V; Greenberg, A; Klein, E; Lenox, RH; Levy, N; Zilberman, I; Zinder, O, 1995)
"This study applied the corticotropin-releasing hormone (CRH) stimulation test to patients with panic disorder, before and during treatment with alprazolam, and to control subjects."7.69Adrenocorticotropic hormone and cortisol responses to corticotropin-releasing hormone: changes in panic disorder and effects of alprazolam treatment. ( Abelson, JL; Curtis, GC; Gold, PW, 1997)
"Out of 69 patients with panic disorder plus agoraphobia who had been in an 8-week controlled study of alprazolam and/or exposure, 31 were followed up at a mean of 3."7.69Agoraphobia and panic disorder: 3.5 years after alprazolam and/or exposure treatment. ( Başoğlu, M; Kiliç, C; Marks, I; Noshirvani, H, 1997)
"This 8-week double-blind placebo-controlled trial investigated the relative efficacy and safety of alprazolam and buspirone in the treatment of panic disorder."7.68The relative efficacy of high-dose buspirone and alprazolam in the treatment of panic disorder: a double-blind placebo-controlled study. ( Harnett-Sheehan, K; Knapp, E; Raj, AB; Sheehan, DV; Soto, S, 1993)
" The charts of 78 panic disorder outpatients treated with alprazolam (mean dose 4."7.68Alprazolam in panic disorder: a retrospective analysis. ( Harvey, DS; Loosen, PT; Shelton, RC; Stewart, PM, 1993)
"The most common pharmacological treatments for panic disorder with agoraphobia (PDA) include the use of imipramine and alprazolam while the most common behavior therapy is the use of graded in vivo exposure."7.68A meta-analysis of treatments for panic disorder with agoraphobia: imipramine, alprazolam, and in vivo exposure. ( Cox, BJ; Endler, NS; Lee, PS; Swinson, RP, 1992)
"Alprazolam-XR is an extended-release formulation of alprazolam designed to deliver sustained therapeutic concentrations for 24 h after once-daily dosing."6.71Alprazolam extended-release in panic disorder. ( Rickels, K, 2004)
" The aim of the XR preparation is to offer less frequent dosing and to reduce interdose anxiety."6.67A double-blind, placebo-controlled, multicenter study with alprazolam and extended-release alprazolam in the treatment of panic disorder. ( Alexander, P; Luthe, L; Munjack, D; Pecknold, J, 1994)
"Panic disorder is a chronic illness with only some degree of spontaneous recovery."6.67Discontinuation reactions to alprazolam in panic disorder. ( Pecknold, JC, 1993)
" If a side effect profile is known, it will be easier for a clinician to choose the right drug and the appropriate management by taking into account compliance, safety and efficacy in each patient under treatment."6.67Adverse effects associated with the short-term treatment of panic disorder with imipramine, alprazolam or placebo. ( Benkert, O; Cassano, GB; Curtis, G; Deltito, J; Hippius, H; Klerman, G; Maier, W; Petracca, A; Shera, D; Toni, C, 1994)
"5 years, 78% of patients remained on medication and the mean dosage of alprazolam and clonazepam did not increase."6.67Long-term outcome after acute treatment with alprazolam or clonazepam for panic disorder. ( Cohen, LS; Meltzer-Brody, S; Otto, MW; Pollack, MH; Rosenbaum, JF; Tesar, GE, 1993)
"Alprazolam therapy was effective and well tolerated at a mean daily dose of 5."6.67Maintenance drug treatment of panic disorder. I. Results of a prospective, placebo-controlled comparison of alprazolam and imipramine. ( Rickels, K; Schweizer, E; Weiss, S; Zavodnick, S, 1993)
"The etiology and optimum treatment of panic disorder remain unclear."6.39Serotonin uptake inhibitors are superior to imipramine and alprazolam in alleviating panic attacks: a meta-analysis. ( Boyer, W, 1995)
"Posttraumatic stress disorder (PTSD) and panic disorder (PD) share several clinical features, and theory postulates that phasic arousal is similarly dysregulated in both."5.30Alprazolam reduces response to loud tones in panic disorder but not in posttraumatic stress disorder. ( Bloch, M; Bonne, O; Peri, T; Shalev, AY, 1998)
" Here, we found that the translocator protein (18 kD) ligand XBD173 enhanced gamma-aminobutyric acid-mediated neurotransmission and counteracted induced panic attacks in rodents in the absence of sedation and tolerance development."5.14Translocator protein (18 kD) as target for anxiolytics without benzodiazepine-like side effects. ( Baghai, TC; Bertaina-Anglade, V; Chaperon, F; Eser, D; Floesser, A; Gentsch, C; Holsboer, F; Kalkman, HO; Kiese, B; Kucher, K; La Rochelle, CD; Landgraf, R; McAllister, KH; Nothdurfter, C; Rammes, G; Rupprecht, R; Schüle, C; Schumacher, M; Troxler, T; Tuerck, D; Uzunov, V, 2009)
"The objective of this study was to ascertain the relationship of alprazolam plasma levels and an anxiety-prone cognitive style to the characteristics and severity of early withdrawal after abrupt discontinuation of alprazolam in 26 patients with panic disorder."5.12Abrupt discontinuation of alprazolam and cognitive style in patients with panic disorder: early effects on mood, performance, and vital signs. ( Antal, EJ; Barnhill, J; Javaid, JI; Matuzas, W; Qualls, C; Starcevic, V; Uhlenhuth, EH, 2006)
"Anxiolytic therapy with the benzodiazepine alprazolam is an established therapy in patients with panic disorder."5.12Anxiolytic therapy with alprazolam increases muscle sympathetic activity in patients with panic disorders. ( Béchir, M; Binggeli, C; Büchi, S; Buddeberg, C; Caduff, C; Chenevard, R; Lüscher, TF; Noll, G; Schwegler, K, 2007)
"This study compares the speed of onset of action of the extended release (XR) formulation of alprazolam with that of the compressed tablet (CT) formulation in a sample of outpatients with DSM-IV panic disorder."5.12The speed of onset of action of alprazolam-XR compared to alprazolam-CT in panic disorder. ( Raj, BA; Sheehan, DV; Sheehan, KH, 2007)
"A compared, 12 week, placebo controlled study, with fixed dose, outpatient study of patients diagnosed with panic disorder with and without agoraphobia according to ICD-10, was conducted to evaluate the efficacy and safety of sertraline and alprazolam."5.11Sertraline and alprazolam in the treatment of panic desorder. ( Fiseković, S; Loga-Zec, S, 2005)
"In 123 panic disorder patients undergoing gradual tapered discontinuation of alprazolam in conjunction with pre-treatment with carbamazepine or placebo, the relationship between measures of 'symptom sensitivity' and 'harm avoidance', and severity of withdrawal symptoms measured as peak severity of symptoms, time before taper needed to be slowed due to symptoms, and ability to complete taper, was examined."5.10Personality and symptom sensitivity predictors of alprazolam withdrawal in panic disorder. ( Ballenger, J; Bell, J; Bystrisky, A; Corrigan, MH; Pollack, M; Rosenbaum, J; Roy-Byrne, P; Rush, AJ; Russo, J; Stewart, R; Stolk, J, 2003)
" Results showed that 75% of the Peoria sample and 76% of the Dartmouth sample were able to discontinue alprazolam therapy, remain abstinent of any type of treatment for panic disorder, and maintain their acute-treatment clinical gains over this follow-up period."5.09Cognitive-behavioral therapy helps prevent relapse and recurrence of panic disorder following alprazolam discontinuation: a long-term follow-up of the Peoria and Dartmouth studies. ( Bruce, TJ; Hegel, MT; Spiegel, DA, 1999)
" A previous study with agoraphobia/panic patients found that the BZ alprazolam impaired memory during an 8-week treatment and residual impairments were still manifest several weeks after drug withdrawal (Curran et al."5.09Long-term effects of alprazolam on memory: a 3.5 year follow-up of agoraphobia/panic patients. ( Başoğlu, M; Curran, HV; Kiliç, C; Marks, IM; Noshirvani, H, 1999)
"Our data suggest the comparable efficacy of alprazolam and imipramine in the short-term treatment of older adults with panic disorder."5.09Treatment of panic disorder in older adults: a pilot study comparison of alprazolam, imipramine, and placebo. ( Sheikh, JI; Swales, PJ, 1999)
"The pharmacokinetics and pharmacodynamics of the benzodiazepine alprazolam (1 mg, administered orally) were compared between eight patients with panic disorder and eight age- and sex-matched healthy volunteers."5.09Differences in pharmacodynamics but not pharmacokinetics between subjects with panic disorder and healthy subjects after treatment with a single dose of alprazolam. ( Ehrenberg, BL; Goddard, JE; Greenblatt, DJ; Harmatz, JS; Kaplan, GB; Shader, RI, 2000)
" As part of a placebo-controlled trial of alprazolam-XR (extended release) administered in combination with cognitive-behavioral therapy in patients with panic disorder, a battery of tests was used to measure neuropsychologic function."5.09Absence of neuropsychologic deficits in patients receiving long-term treatment with alprazolam-XR for panic disorder. ( Auerbach, M; Gladsjo, JA; Hahn, T; Haze, A; Judd, LL; McKinney, R; Oliver, T; Rabin, A; Rapaport, MH, 2001)
") and to clonidine (150 micrograms) were measured in 10 outpatients with panic disorder before and after 30 days of 2-2."5.08Alpha 2-adrenergic receptor sensitivity in panic disorder: I. GH response to GHRH and clonidine stimulation in panic disorder. ( Bellodi, L; Brambilla, F; Garberi, A; Nobile, P; Perna, G, 1995)
"The cortisol responses to acute administration of saline and of clonidine (Clon), 150 micrograms IV, were examined in 12 patients with panic disorder and agoraphobia, before and after 32 days of alprazolam therapy (2."5.08Alpha 2-adrenergic receptor sensitivity in panic disorder: II. Cortisol response to clonidine stimulation in panic disorder. ( Arancio, C; Bellodi, L; Brambilla, F; Nobile, P; Perna, G, 1995)
"22 patients with panic disorder (diagnosis according to ICD-10) were treated with alprazolam (monotherapy) in a dose of 1-2,5 mg/daily during 6 weeks."5.08[The efficacy of alprazolam in the therapy of panic disorders]. ( Diukova, GM; Petrova, EP; Smirnov, SV; Tumalaeva, ZN; Vorob'eva, OV, 1995)
"Cerebrospinal fluid (CSF) gamma-aminobutyric acid (GABA) levels were measured in 11 patients with panic disorder (PD) prior to and following 7 months of treatment with alprazolam or imipramine and in six neurological control patients."5.08Cerebrospinal fluid gamma-aminobutyric acid in patients with panic disorder. ( Halonen, T; Jolkkonen, J; Lepola, U; Riekkinen, P; Rimón, R, 1995)
"23 patients with a diagnosis of panic disorder with agoraphobia were randomly assigned to 8 weeks' treatment with alprazolam or placebo."5.08Behavioural aggression in panic disorder after 8 weeks' treatment with alprazolam. ( Bond, AJ; Bruce, MS; Curran, HV; O'Sullivan, G; Shine, P, 1995)
"Alprazolam has proven efficacy as a treatment for panic disorder, but the place of other benzodiazepines is less well established."5.08Diazepam versus alprazolam for the treatment of panic disorder. ( Burrows, GD; Cook, BL; Garvey, MJ; Judd, FK; Marriott, P; Norman, TR; Noyes, R; Reich, JH, 1996)
"A group of 20 patients who met the DSM-III-R criteria for panic disorder with or without agoraphobia underwent a 35% carbon dioxide (CO2) challenge after either 1 mg alprazolam or placebo in a double-blind, randomized, cross-over design."5.08Alprazolam premedication and 35% carbon dioxide vulnerability in panic patients. ( Griez, E; Hauzer, R; Meijer, J; Pols, H; Verburg, K, 1996)
" We reanalyzed a study of 81 panic patients treated with placebo, alprazolam 2 mg or 6 mg, or imipramine 225 mg daily to investigate the effect of baseline pathology and selective effects of treatment on biological and cognitive components of panic disorder."5.08Growing placebo response rate: the problem in recent therapeutic trials? ( Matuzas, W; Thompson, PM; Uhlenhuth, EH; Warner, TD, 1997)
"The reinforcing effects of alprazolam were investigated in 14 patients who had generalized anxiety or panic disorder, but were not current users/abusers of other psychoactive substances."5.08Alprazolam-reinforced medication use in outpatients with anxiety. ( Creson, DR; Meisch, RA; Roache, JD; Shah, NN; Stanley, MA, 1997)
"We determined whether blindness in a double-blind randomized controlled trial of alprazolam and exposure therapies in patients with panic disorder and agoraphobia was maintained in assessors and patients, what were the factors related to "unblinding," and whether unblinding was associated with clinical outcome."5.08Double-blindness procedures, rater blindness, and ratings of outcome. Observations from a controlled trial. ( Başoğlu, M; Livanou, M; Marks, I; Swinson, R, 1997)
"Fifty-two subjects with panic disorder and generalized anxiety disorder were interviewed 12-18 months after they completed an acute treatment study (9-11 weeks) with alprazolam followed by blind and controlled drug discontinuation."5.08Subjective experience and attitudes towards participation in clinical trials among patients with anxiety disorders. ( Klein, E; Lenox, RH; Malel, D; Zilberman, I, 1997)
" The efficacy of alprazolam and placebo in panic disorder with agoraphobia, and the side-effect and adverse effect profiles of both drug groups were measured."5.07Safety and side-effects of alprazolam. Controlled study in agoraphobia with panic disorder. ( Başoğlu, M; Kirby, M; Kuch, K; Marks, IM; Noshirvani, H; O'Sullivan, GH; Swinson, R, 1994)
" Eighty-two agoraphobics with panic disorder were randomly allocated to one of four treatment groups resulting from a combination of two drug treatments (alprazolam or placebo) and two psychological treatments (exposure or relaxation)."5.07Memory functions, alprazolam and exposure therapy: a controlled longitudinal study of agoraphobia with panic disorder. ( Bond, A; Bruce, M; Curran, HV; Lader, M; Lelliot, P; Marks, I; O'Sullivan, G; Shine, P, 1994)
"Pre-treatment predictors of treatment outcome were examined in a group of 144 patients with panic disorder and agoraphobia randomly allocated to alprazolam+exposure (AE), placebo+exposure (PE), alprazolam+relaxation (AR), and placebo+relaxation (PR)."5.07Pre-treatment predictors of treatment outcome in panic disorder and agoraphobia treated with alprazolam and exposure. ( Başoğlu, M; Kuch, K; Marks, IM; Noshirvani, H; O'Sullivan, G; Swinson, RP, 1994)
"In a controlled trial of alprazolam and exposure in 154 patients with panic disorder with agoraphobia, relations between panic, anticipatory anxiety, and phobic avoidance were examined."5.07Relationship of panic, anticipatory anxiety, agoraphobia and global improvement in panic disorder with agoraphobia treated with alprazolam and exposure. ( Başoğlu, M; Kiliç, C; Kuch, K; Marks, IM; Noshirvani, H; O'Sullivan, G; Swinson, RP, 1994)
"Patients with panic disorder plus agoraphobia had 8 weeks of drug treatment (alprazolam or placebo) plus psychological treatment (exposure or relaxation)."5.07Alprazolam and exposure for panic disorder with agoraphobia. Attribution of improvement to medication predicts subsequent relapse. ( Başoğlu, M; Brewin, CR; Kiliç, C; Marks, IM; Swinson, RP, 1994)
"Forty Danish panic disorder patients participating in a placebo controlled study of alprazolam and imipramine (The Cross National Collaborative Panic Study, Phase II) were followed up by a telephone interview three years later, with essentially the same battery of evaluation procedures applied at baseline, end of study, and follow-up."5.07Three years follow-up of panic disorder patients: a naturalistic study. ( Rosenberg, NK; Rosenberg, R, 1994)
"This study was designed to examine the possibility that patients with panic disorder are especially vulnerable to alprazolam withdrawal, as well as to evaluate the efficacy of carbamazepine as adjunctive treatment during alprazolam discontinuation."5.07Alprazolam withdrawal in patients with panic disorder and generalized anxiety disorder: vulnerability and effect of carbamazepine. ( Colin, V; Klein, E; Lenox, RH; Stolk, J, 1994)
"This study examines clinical predictors of outcome for patients with panic disorder and depression in a 16 week, placebo-controlled trial of alprazolam and imipramine (n = 126)."5.07Anxiety psychopathology predictive of outcome in patients with panic disorder and depression treated with imipramine, alprazolam and placebo. ( Deltito, JA; Keller, MB; Leon, A; Otto, MW; Pollack, MH; Rosenbaum, JF; Sachs, GS; Shear, MK, 1994)
"The primary aim of this study was to determine if pretreatment with a single dose of alprazolam reduces anxiety and panic provoked by the inhalation of 35% carbon dioxide (CO2) in patients with panic disorder."5.07Alprazolam blockade of CO2-provoked panic in patients with panic disorder. ( Asnis, GM; Sanderson, WC; Wetzler, S, 1994)
" The group with prominent respiratory symptoms suffered more spontaneous panic attacks and responded to imipramine, whereas the group without prominent respiratory symptoms suffered more situational panic attacks and responded more to alprazolam."5.07Subtyping of panic disorder by symptom profile. ( Brandon, S; Briggs, AC; Stretch, DD, 1993)
" The present study provided systematic data from a double blind comparison of maintenance therapy (up to 8 months) of panic disorder with or without agoraphobia with alprazolam, imipramine, or placebo in 181 patients who had responded to the same regimen in a randomized 8-week treatment trial."5.07Maintenance drug therapy of panic disorder. ( Ayuso, JL; Cassano, GB; Curtis, GC; Massana, J; Perugi, G; Udina, C, 1993)
"Date from a panic disorder treatment study with 506 patients, comparing alprazolam and placebo in a double-blind manner for 8 weeks, were analyzed to identify demographic and clinical characteristics of the patients that might predict response to treatment."5.07Predictors of response to alprazolam and placebo in patients with panic disorder. ( Ballenger, JC; Lydiard, RB; Mihalko, D; Noyes, R; Sievers, G; Woodman, CL, 1994)
"The authors investigated whether cognitive behavioral treatment could facilitate discontinuation of alprazolam therapy and maintenance of drug abstinence among panic disorder patients treated with alprazolam doses sufficient to suppress spontaneous panic attacks."5.07Does cognitive behavior therapy assist slow-taper alprazolam discontinuation in panic disorder? ( Bruce, TJ; Gregg, SF; Nuzzarello, A; Spiegel, DA, 1994)
"One hundred ninety-four patients with diagnosis of agoraphobia with panic attacks or panic disorder with limited phobic avoidance underwent a 1-week placebo washout before being randomly assigned to groups receiving 8 weeks of double-blind treatment with either sustained-release alprazolam or placebo."5.07Double-blind, placebo-controlled study of a once-a-day, sustained-release preparation of alprazolam for the treatment of panic disorder. ( Patterson, W; Rickels, K; Rosenthal, M; Schweizer, E, 1993)
"Fifty-five patients with moderate to sever panic disorder were treated for 9 weeks with alprazolam or imipramine and were then, except for one patient who had committed suicide, re-examined after on average 3 years of treatment."5.07Three-year follow-up of patients with panic disorder after short-term treatment with alprazolam and imipramine. ( Lepola, UM; Riekkinen, PJ; Rimón, RH, 1993)
"A series of 237 patients with DSM-III-diagnosed panic disorder, or agoraphobia with panic attacks, received alprazolam as part of the placebo-controlled Cross-National Collaborative Panic Study."5.07Plasma alprazolam concentrations. Relation to efficacy and side effects in the treatment of panic disorder. ( Greenblatt, DJ; Harmatz, JS; Shader, RI, 1993)
"Outpatients treated for panic disorder with alprazolam or clonazepam for a minimum of 6 months and expressing a desire to stop taking the medication (N = 33) were randomly assigned to one of two taper conditions: a slow taper condition alone or a slow taper condition in conjunction with 10 weeks of group cognitive-behavioral therapy."5.07Discontinuation of benzodiazepine treatment: efficacy of cognitive-behavioral therapy for patients with panic disorder. ( Meltzer-Brody, S; Otto, MW; Pollack, MH; Reiter, SR; Rosenbaum, JF; Sachs, GS, 1993)
"Forty-eight patients with panic disorder completing 8 months of maintenance treatment with alprazolam (mean dose, 5."5.07Maintenance drug treatment for panic disorder. II. Short- and long-term outcome after drug taper. ( Rickels, K; Schweizer, E; Weiss, S; Zavodnick, S, 1993)
"The present study is aimed at assessing a 48-outpatient sample that had been diagnosed as Panic Disorder cases: Approximately 5 years ago, patients had been treated with either Alprazolam, Imipramine or placebo during an 8-week double-blind trial."5.07[Patients with panic disorder: a 5-year follow-up study]. ( Arévalo, W; Gaviria, LF; Leon, A; León, CA, 1992)
"The acute effects of diazepam on plasma GABA were determined in 18 patients with panic disorder, 13 patients with generalized anxiety disorder and 20 healthy controls."5.07Effect of acute and chronic benzodiazepines on plasma GABA in anxious patients and controls. ( Cowley, DS; Greenblatt, DJ; Hommer, D; Kramer, GL; Petty, F; Roy-Byrne, PP, 1992)
" According to logistic regression analysis, the relationships between plasma alprazolam concentration and response, as reflected by number of panic attacks reported, phobia ratings, physicians' and patients' ratings of global improvement, and the emergence of side effects, were significant."5.07Alprazolam plasma concentrations and treatment response in panic disorder and agoraphobia. ( Antal, E; Ballenger, JC; DuPont, R; Lesser, IM; Lydiard, RB; Rubin, RT, 1992)
"The reactivity of 40 panic disorder patients on mental arithmetic, cold pressor, and 5% CO2 inhalation stressors was tested before and after 8 weeks of treatment with imipramine, alprazolam, or placebo."5.07Imipramine and alprazolam effects on stress test reactivity in panic disorder. ( Agras, WS; Ehlers, A; Haddad, JM; Maddock, RJ; Margraf, J; Roth, WT; Taylor, CB, 1992)
"To investigate whether alprazolam (ALP) coprescription early in the imipramine (IMI) treatment of panic disorder would improve overall treatment response to IMI alone, 48 panic disorder patients were randomly assigned to receive either IMI plus placebo or IMI plus ALP for 4-6 weeks, followed by 2 weeks of IMI plus placebo-ALP taper and 2 more weeks of IMI alone."5.07Controlled trial of alprazolam supplementation during imipramine treatment of panic disorder. ( Charney, DS; Heninger, GR; Koleszar, AS; Krystal, JH; Nagy, LM; Woods, SW, 1992)
"A recently reported multinational, 8-week double-blind, placebo-controlled study assessing the efficacy of alprazolam versus placebo in the treatment of panic disorder indicated significant differences favoring alprazolam."5.07A fixed-dose study of alprazolam 2 mg, alprazolam 6 mg, and placebo in panic disorder. ( Ballenger, JC; DuPont, R; Laraia, M; Lesser, IM; Lydiard, RB; Rubin, RT, 1992)
"We studied the efficacy of propranolol (Inderal) compared to alprazolam (Xanax) in 29 patients with a diagnosis of agoraphobia with panic disorder or panic disorder with or without limited phobic avoidance in a 6-week double-blind controlled experiment."5.07A controlled study of alprazolam and propranolol in panic-disordered and agoraphobic outpatients. ( Friedman, MJ; Hauri, PJ; McHugo, GJ; Ravaris, CL, 1991)
"The impact of the avoidance behaviour on the psychopharmacological treatment of panic disorder was explored in the Cross National Collaborative Panic Study (n = 1134 patients); in this double blind randomized trial alprazolam, imipramine and placebo were compared during an 8-week treatment period."5.07Avoidance behaviour: a predictor of the efficacy of pharmacotherapy in panic disorder? ( Argyle, N; Benkert, O; Brandon, S; Buller, R; Lavori, P; Maier, W; Roth, SM, 1991)
"To investigate the potential impact of increasing prescription rates of alprazolam for the treatment of panic disorder (PD) in Australia through a review of efficacy, tolerability and adverse outcome literature."4.88The role of alprazolam for the treatment of panic disorder in Australia. ( Berk, M; Giorlando, F; Moylan, S; Nordfjærn, T, 2012)
"We performed a meta-analysis of all single- or double-blind, randomized controlled trials comparing alprazolam to another benzodiazepine in the treatment of adult patients meeting the Diagnostic and Statistical Manual of Mental Disorders, Third or Fourth Edition, criteria for panic disorder or agoraphobia with panic attacks."4.87The efficacy and safety of alprazolam versus other benzodiazepines in the treatment of panic disorder. ( Berk, M; Moylan, S; Rogerson, J; Staples, J; Stein, DJ; Ward, SA, 2011)
"Alprazolam is a benzodiazepine derivative that is currently used in the treatment of generalized anxiety, panic attacks with or without agoraphobia, and depression."4.82Clinical pharmacology, clinical efficacy, and behavioral toxicity of alprazolam: a review of the literature. ( Verster, JC; Volkerts, ER, 2004)
"Alprazolam was the first pharmacological agent to be approved for the treatment of panic disorder."4.80Efficacy studies of alprazolam in panic disorder. ( Spiegel, DA, 1998)
"A review of the worldwide published literature was conducted to assess the efficacy and safety of alprazolam for the treatment of anxiety disorders, panic disorder, and depression in comparison with those of other active drugs (including other benzodiazepines and antidepressant medications)."4.78A comparison of the safety and efficacy of alprazolam versus other agents in the treatment of anxiety, panic, and depression: a review of the literature. ( Cohon, MS; Jonas, JM, 1993)
"Therapeutic efficacy for depression and panic disorder has been demonstrated with the triazolobenzodiazepine alprazolam."4.78Alprazolam and depression: a review of risks and benefits. ( Fawcett, J; Kravitz, HM; Newman, AJ, 1993)
" Doxapram is an analeptic capable of inducing panic attacks with respiratory symptoms in individuals diagnosed with the disorder; however, its neuroanatomical targets and its effects on experimental animals remain uncharacterized."4.02Intravenous doxapram administration as a potential model of panic attacks in rats. ( Batista, LA; Brianis, RC; Haibara, AS; Lopes, JB; Moreira, FA, 2021)
" Previously, she was treated for a longer period with alprazolam due to panic disorder."3.80Pseudopheochromocytoma induced by anxiolytic withdrawal. ( Barna, S; Becs, G; Czifra, A; Erdei, A; Kovács, P; Páll, A; Páll, D; Paragh, G; Pfliegler, G; Sira, L; Szabó, Z, 2014)
") sodium lactate (NaLac) infusions, in a manner similar to what occurs in patients with panic disorder."3.79Group II metabotropic glutamate receptor type 2 allosteric potentiators prevent sodium lactate-induced panic-like response in panic-vulnerable rats. ( Engleman, EA; Fitz, SD; Johnson, PL; Schkeryantz, JM; Shekhar, A; Svensson, KA, 2013)
"We experienced an 11-year-old boy with panic disorder responding remarkably to paroxetine."3.7411-year-old boy with panic disorder responding to paroxetine. ( Matsumoto, H; Tamai, Y, 2007)
"This study investigated an anxiety-prone cognitive style (measured by the Anxious Thoughts and Tendencies Questionnaire, AT&T) as a predictor of the acute response to increasing alprazolam plasma levels in panic disorder."3.74Cognitive style, alprazolam plasma levels, and treatment response in panic disorder. ( Antal, EJ; Barnhill, J; Javaid, JI; Matuzas, W; Qualls, C; Starcevic, V; Uhlenhuth, EH, 2008)
"Escitalopram, the active enantiomer of the selective serotonin reuptake inhibitor (SSRI) citalopram, has effects in animal models for the detection of antidepressant and anxiolytic effect and in patients with major depressive and anxiety disorders."3.73Prediction of anti-panic properties of escitalopram in the dorsal periaqueductal grey model of panic anxiety. ( Hogg, S; Jessa, M; Michan, L, 2006)
" Changes in the plasma cortisol level were reported in a male patient with panic disorder during the period of low-dose alprazolam treatment (mean 0."3.70Decreased plasma cortisol level during alprazolam treatment of panic disorder: a case report. ( Fukuda, M; Hata, A; Hiramatsu, K; Iwanami, A; Kasai, K; Nakagome, K; Takazawa, S, 1998)
"Plasma concentrations of tumor necrosis factor-alpha (TNF-alpha) were measured in 10 outpatients with panic disorder, twice (at a 48-h interval) before and twice on days 30-32 of treatment with alprazolam (2-2."3.70Plasma levels of tumor necrosis factor-alpha in patients with panic disorder: effect of alprazolam therapy. ( Bellodi, L; Brambilla, F; Perna, G, 1999)
"In a previous paper the authors reported survival data for 20 panic disorder patients whose therapeutic doses of alprazolam were tapered by one of two methods: slow, flexible drug taper with supportive medical management or the same taper procedure carried out concurrently with cognitive behavior therapy."3.69Predictors of alprazolam discontinuation with and without cognitive behavior therapy in panic disorder. ( Bruce, TJ; Gregg, SF; Nuzzarello, A; Spiegel, DA, 1995)
"Plasma interleukin-1 beta (IL-1 beta) concentrations were measured in 10 outpatients with panic disorder before and on days 30 and 32 of treatment with alprazolam (2-2."3.69Plasma interleukin-1 beta concentrations in panic disorder. ( Bellodi, L; Bertani, A; Brambilla, F; Panerai, A; Perna, G; Sacerdote, P, 1994)
"The aim of the current study was to determine the degree to which patients with panic disorder develop tolerance to subjective and physiological effects of benzodiazepine after chronic treatment with alprazolam."3.69Benzodiazepine sensitivity in panic disorder: effects of chronic alprazolam treatment. ( Cowley, DS; Greenblatt, DJ; Hommer, DW; Nemeroff, CB; Radant, A; Ritchie, JC; Roy-Byrne, PP, 1995)
"The authors report on seven consecutive openly treated patients with panic disorder who showed inadequate antipanic responses to treatment regimens including either a tricyclic (TCA) or fluoxetine."3.69Augmentation strategies with tricyclic or fluoxetine treatment in seven partially responsive panic disorder patients. ( Coplan, JD; Gorman, JM; Papp, LA; Tiffon, L, 1994)
"Follow-up clinical data were obtained for 18 of 20 patients with panic disorder who participated in a detailed study of HPA axis activity in panic, both before and during their treatment with alprazolam."3.69Hypothalamic-pituitary-adrenal axis activity in panic disorder: prediction of long-term outcome by pretreatment cortisol levels. ( Abelson, JL; Curtis, GC, 1996)
"Thirty-six patients with panic disorder (PD) and 35 patients with generalized anxiety disorder (GAD) participated in an open alprazolam treatment phase that preceded controlled withdrawal from alprazolam."3.69Clinical similarity and biological diversity in the response to alprazolam in patients with panic disorder and generalized anxiety disorder. ( Colin, V; Greenberg, A; Klein, E; Lenox, RH; Levy, N; Zilberman, I; Zinder, O, 1995)
"This study applied the corticotropin-releasing hormone (CRH) stimulation test to patients with panic disorder, before and during treatment with alprazolam, and to control subjects."3.69Adrenocorticotropic hormone and cortisol responses to corticotropin-releasing hormone: changes in panic disorder and effects of alprazolam treatment. ( Abelson, JL; Curtis, GC; Gold, PW, 1997)
"Out of 69 patients with panic disorder plus agoraphobia who had been in an 8-week controlled study of alprazolam and/or exposure, 31 were followed up at a mean of 3."3.69Agoraphobia and panic disorder: 3.5 years after alprazolam and/or exposure treatment. ( Başoğlu, M; Kiliç, C; Marks, I; Noshirvani, H, 1997)
"This 8-week double-blind placebo-controlled trial investigated the relative efficacy and safety of alprazolam and buspirone in the treatment of panic disorder."3.68The relative efficacy of high-dose buspirone and alprazolam in the treatment of panic disorder: a double-blind placebo-controlled study. ( Harnett-Sheehan, K; Knapp, E; Raj, AB; Sheehan, DV; Soto, S, 1993)
" The charts of 78 panic disorder outpatients treated with alprazolam (mean dose 4."3.68Alprazolam in panic disorder: a retrospective analysis. ( Harvey, DS; Loosen, PT; Shelton, RC; Stewart, PM, 1993)
"Immunological, neuroendocrine and psychological parameters were examined in 14 psychophysically healthy subjects and in 17 panic disorder patients before and after a 30-day course of alprazolam therapy."3.68Psychoimmunoendocrine aspects of panic disorder. ( Battaglia, M; Bellodi, L; Brambilla, F; Diaferia, G; Panerai, A; Perna, G; Petraglia, F; Sacerdote, P; Sciuto, G, 1992)
"The most common pharmacological treatments for panic disorder with agoraphobia (PDA) include the use of imipramine and alprazolam while the most common behavior therapy is the use of graded in vivo exposure."3.68A meta-analysis of treatments for panic disorder with agoraphobia: imipramine, alprazolam, and in vivo exposure. ( Cox, BJ; Endler, NS; Lee, PS; Swinson, RP, 1992)
"Alprazolam and diazepam were associated with a lower dropout rate compared to placebo and were ranked as the most tolerated of all the medications examined."3.01Pharmacological treatments in panic disorder in adults: a network meta-analysis. ( Barbui, C; Bighelli, I; Caldwell, DM; Cipriani, A; Davies, SJ; Dawson, S; Dias, S; Furukawa, TA; Guaiana, G; Imai, H; Koesters, M; Meader, N; Pompoli, A; Robertson, L; Tajika, A, 2023)
"Despite its acute efficacy for the treatment of panic disorder, benzodiazepines (BZs) are associated with a withdrawal syndrome that closely mimics anxiety sensations, leading to difficulty with treatment discontinuation and often disorder relapse."2.75Efficacy of CBT for benzodiazepine discontinuation in patients with panic disorder: Further evaluation. ( Farach, FJ; McHugh, RK; Otto, MW; Pollack, MH; Simon, NM; Worthington, JJ, 2010)
"Alprazolam-XR is an extended-release formulation of alprazolam designed to deliver sustained therapeutic concentrations for 24 h after once-daily dosing."2.71Alprazolam extended-release in panic disorder. ( Rickels, K, 2004)
"Patients with panic disorder have blunted growth hormone (GH) responses to clonidine, suggesting subsensitivity of post-synaptic alpha(2)-adrenoreceptors, presumably in response to excessive central noradrenergic outflow."2.71Twenty-four hour growth hormone secretion in patients with panic disorder. ( Abelson, JL; Curtis, GC; Uhde, TW, 2005)
"Alprazolam clearly was preferred over placebo; however, there were large between-subjects differences in the amount of medication used."2.69Predictors of individual differences in alprazolam self-medication. ( Oswald, LM; Rhoades, HM; Roache, JD, 1999)
"The course of panic disorder is not uniform."2.68Long-term follow-up after a drug trial for panic disorder. ( Amering, M; Ballenger, JC; Briggs, A; Buller, R; Cassano, G; Garvey, M; Katschnig, H; Klerman, GL; Roth, M; Stolk, JM, 1995)
" The aim of the XR preparation is to offer less frequent dosing and to reduce interdose anxiety."2.67A double-blind, placebo-controlled, multicenter study with alprazolam and extended-release alprazolam in the treatment of panic disorder. ( Alexander, P; Luthe, L; Munjack, D; Pecknold, J, 1994)
"Panic disorder is a chronic illness with only some degree of spontaneous recovery."2.67Discontinuation reactions to alprazolam in panic disorder. ( Pecknold, JC, 1993)
" If a side effect profile is known, it will be easier for a clinician to choose the right drug and the appropriate management by taking into account compliance, safety and efficacy in each patient under treatment."2.67Adverse effects associated with the short-term treatment of panic disorder with imipramine, alprazolam or placebo. ( Benkert, O; Cassano, GB; Curtis, G; Deltito, J; Hippius, H; Klerman, G; Maier, W; Petracca, A; Shera, D; Toni, C, 1994)
"5 years, 78% of patients remained on medication and the mean dosage of alprazolam and clonazepam did not increase."2.67Long-term outcome after acute treatment with alprazolam or clonazepam for panic disorder. ( Cohen, LS; Meltzer-Brody, S; Otto, MW; Pollack, MH; Rosenbaum, JF; Tesar, GE, 1993)
"Alprazolam therapy was effective and well tolerated at a mean daily dose of 5."2.67Maintenance drug treatment of panic disorder. I. Results of a prospective, placebo-controlled comparison of alprazolam and imipramine. ( Rickels, K; Schweizer, E; Weiss, S; Zavodnick, S, 1993)
" The majority (67%) of patients interviewed discontinued alprazolam for a period of at least 3 days after a gradual dosage reduction schedule over a 4-week period at the end of the long-term treatment study."2.67Discontinuation of alprazolam after long-term treatment of panic-related disorders. ( Ballenger, JC; Burrows, GD; DuPont, RL; Noyes, R; Pecknold, JC; Rifkin, A; Rubin, RT; Swinson, RP, 1992)
"Help-seeking behaviour for treatment of panic disorder was investigated in the sample of the Cross-National Collaborative Panic Study Second Phase."2.67Center differences and cross-national invariance in help-seeking for panic disorder. A report from the cross-national collaborative panic study. ( Amering, M; Buller, R; Deltito, JA; Katschnig, H; Klerman, GL; Lavori, PW; Winter, P, 1992)
" Small sample sizes in many panic provocation studies, lack of dose-response aspects, and still-insufficient knowledge about the biological underpinning of experimental and spontaneous panic limit the interpretation of existing findings and should inspire further research."2.47Experimental panic provocation in healthy man-a translational role in anti-panic drug development? ( Kellner, M, 2011)
"Because the other standard treatments of panic disorder, the SSRIs, have a slow onset of action, adding an extended-release benzodiazepine to the treatment regimen for the initial 6 to 8 weeks could serve as an effective bridge until the desired SSRI effect is realized."2.41The management of panic disorder. ( Sheehan, DV, 2002)
"Clonazepam has several advantages over other benzodiazepines and can be considered a first-line agent for panic disorder."2.40Use of benzodiazepines in panic disorder. ( Davidson, JR, 1997)
"The etiology and optimum treatment of panic disorder remain unclear."2.39Serotonin uptake inhibitors are superior to imipramine and alprazolam in alleviating panic attacks: a meta-analysis. ( Boyer, W, 1995)
"Drug treatment of panic disorder is reviewed with focus on recent controlled studies."2.38Drug treatment of panic disorder. ( Rosenberg, R, 1993)
"Panic disorder is a serious, often chronic condition that warrants vigorous treatment."2.38Psychopharmacological treatment of panic disorder. ( Bowden, CL, 1992)
" Chronic administration of both paroxetine and alprazolam decreased these responses with morphological correlates between the panicolytic effect of both drugs administered at the highest dose and decreases in Fos protein-immunolabeled perikarya found in the amygdaloid complex, hypothalamus and periaqueductal gray matter columns, which are structures that make up the encephalic aversion system."1.48The Rodent-versus-wild Snake Paradigm as a Model for Studying Anxiety- and Panic-like Behaviors: Face, Construct and Predictive Validities. ( Coimbra, JPC; Coimbra, NC; de Freitas, RL; Dos Anjos-Garcia, T; Falconi-Sobrinho, LL; Laure, CJ; Paschoalin-Maurin, T, 2018)
"Panic disorder is a severe anxiety disorder with recurrent, debilitating panic attacks."1.36A key role for orexin in panic anxiety. ( Brundin, L; Dietrich, A; Fitz, SD; Goddard, AW; Johnson, PL; Minick, PE; Sanghani, S; Shekhar, A; Träskman-Bendz, L; Truitt, W, 2010)
"The management of the patient's withdrawal symptoms is described."1.31Pharmacokinetically induced benzodiazepine withdrawal. ( Ninan, PT, 2001)
"Posttraumatic stress disorder (PTSD) and panic disorder (PD) share several clinical features, and theory postulates that phasic arousal is similarly dysregulated in both."1.30Alprazolam reduces response to loud tones in panic disorder but not in posttraumatic stress disorder. ( Bloch, M; Bonne, O; Peri, T; Shalev, AY, 1998)
"T cells from patients with untreated panic disorder exhibited significantly higher cholecystokinin-4-induced calcium mobilization than those from healthy controls or patients with treated panic disorder."1.29CCK-4-induced calcium mobilization in T cells is enhanced in panic disorder. ( Akiyoshi, J; Fujii, I; Isogawa, K; Kuga, K; Miyamoto, M; Moriyama, T; Sasaki, I; Yamada, K; Yamamoto, H, 1996)
"In 2 patients Graves' disease occurred in the setting of previously established euthyroid panic disorder."1.29Graves'disease after the onset of panic disorder. ( Kubo, C; Matsubayashi, S; Matsumoto, Y; Morita, T; Mukuta, T; Tamagawa, K; Tamaí, H, 1996)

Research

Studies (190)

TimeframeStudies, this research(%)All Research%
pre-19901 (0.53)18.7374
1990's139 (73.16)18.2507
2000's32 (16.84)29.6817
2010's16 (8.42)24.3611
2020's2 (1.05)2.80

Authors

AuthorsStudies
Guaiana, G1
Meader, N1
Barbui, C1
Davies, SJ1
Furukawa, TA1
Imai, H1
Dias, S1
Caldwell, DM1
Koesters, M1
Tajika, A1
Bighelli, I1
Pompoli, A1
Cipriani, A1
Dawson, S1
Robertson, L1
Batista, LA2
Lopes, JB1
Brianis, RC1
Haibara, AS2
Moreira, FA2
Paschoalin-Maurin, T1
Dos Anjos-Garcia, T1
Falconi-Sobrinho, LL1
de Freitas, RL1
Coimbra, JPC1
Laure, CJ1
Coimbra, NC1
Baltás, P1
Páll, A1
Becs, G1
Erdei, A1
Sira, L1
Czifra, A1
Barna, S1
Kovács, P1
Páll, D1
Pfliegler, G1
Paragh, G1
Szabó, Z1
Schenberg, LC1
Okumura, A1
Morii, A1
Kiriyama, M1
Takamatsu, H1
Shimizu, M1
Yasui, S1
Takagawa, K1
Bailey, JE1
Papadopoulos, A1
Seddon, K1
Nutt, DJ1
Rupprecht, R2
Rammes, G1
Eser, D2
Baghai, TC2
Schüle, C1
Nothdurfter, C1
Troxler, T1
Gentsch, C1
Kalkman, HO1
Chaperon, F1
Uzunov, V1
McAllister, KH1
Bertaina-Anglade, V1
La Rochelle, CD1
Tuerck, D1
Floesser, A1
Kiese, B1
Schumacher, M1
Landgraf, R1
Holsboer, F1
Kucher, K1
Hooper, S1
Bruno, R1
Sharpe, M1
Tahmindjis, A1
Johnson, PL2
Truitt, W1
Fitz, SD2
Minick, PE1
Dietrich, A1
Sanghani, S1
Träskman-Bendz, L1
Goddard, AW1
Brundin, L1
Shekhar, A2
Otto, MW6
McHugh, RK1
Simon, NM1
Farach, FJ1
Worthington, JJ1
Pollack, MH10
Tamai, Y1
Matsumoto, H1
Sabljić, V1
Rakun, R1
Ružić, K1
Grahovac, T1
Roberson-Nay, R1
Latendresse, SJ1
Kendler, KS1
Moylan, S2
Staples, J1
Ward, SA1
Rogerson, J1
Stein, DJ1
Berk, M2
Marazziti, D1
Carlini, M1
Dell'Osso, L1
Kellner, M1
Giorlando, F1
Nordfjærn, T1
Starcevic, V5
Lampe, L1
Engleman, EA1
Svensson, KA1
Schkeryantz, JM1
Ninan, PT2
Kolar, D1
Latas, M1
Bogojevic, G1
Kelin, K1
Sheehan, DV4
Roy-Byrne, P1
Russo, J1
Pollack, M1
Stewart, R1
Bystrisky, A1
Bell, J1
Rosenbaum, J1
Corrigan, MH1
Stolk, J2
Rush, AJ1
Ballenger, J2
Litvintsev, SV1
Reznik, AM1
Kvashnina, NV1
Arbuzov, AL1
Krylov, KE1
Boerner, RJ1
Andersch, S1
Hetta, J1
Verster, JC1
Volkerts, ER1
Rickels, K6
Abelson, JL3
Curtis, GC4
Uhde, TW1
Schreier, H1
Martinez, K1
Fiseković, S1
Loga-Zec, S1
Choi, YH1
Vincelli, F1
Riva, G1
Wiederhold, BK1
Lee, JH1
Park, KH1
Prasko, J1
Houbová, P1
Novák, T1
Záleský, R1
Espa-Cervená, K1
Pasková, B1
Vyskocilová, J1
Uhlenhuth, EH5
Leon, AC7
Matuzas, W4
Cerra, D1
Hogg, S1
Michan, L1
Jessa, M1
Zwanzger, P1
Völkel, N1
Möller, HJ1
Padberg, F1
Qualls, C2
Antal, EJ2
Javaid, JI2
Barnhill, J2
Himmerich, H1
Nickel, T1
Dalal, MA1
Müller, MB1
Béchir, M1
Schwegler, K1
Chenevard, R1
Binggeli, C1
Caduff, C1
Büchi, S1
Buddeberg, C1
Lüscher, TF1
Noll, G1
Benjamin, AB1
Sheehan, KH1
Raj, BA1
Virit, O1
Savas, HA1
Shear, MK4
Rosenbaum, JF9
Keller, MB3
Marzuk, PM1
Portera, L5
Boyer, W1
Bruce, TJ3
Spiegel, DA5
Gregg, SF2
Nuzzarello, A2
Brambilla, F6
Bellodi, L6
Perna, G6
Bertani, A1
Panerai, A3
Sacerdote, P3
Cowley, DS2
Roy-Byrne, PP2
Radant, A1
Ritchie, JC1
Greenblatt, DJ5
Nemeroff, CB1
Hommer, DW1
O'Sullivan, GH1
Noshirvani, H6
Başoğlu, M10
Marks, IM7
Swinson, R2
Kuch, K3
Kirby, M1
Pecknold, J2
Luthe, L1
Munjack, D1
Alexander, P1
Garberi, A2
Nobile, P2
Arancio, C1
Shader, RI4
Curran, HV3
Bond, A1
O'Sullivan, G5
Bruce, M1
Marks, I3
Lelliot, P1
Shine, P2
Lader, M1
Klein, DF1
Swinson, RP6
Kiliç, C4
Brewin, CR1
Rosenberg, NK1
Rosenberg, R2
Labbate, LA1
Tesar, GM1
Jonas, JM2
Piper, A1
Klein, E3
Colin, V2
Lenox, RH3
Rosenfeld, DS1
Furman, Y1
Baron, C1
Marcotte, JE1
Sachs, GS3
Leon, A3
Deltito, JA3
Sanderson, WC1
Wetzler, S1
Asnis, GM1
Mant, A2
Kaspi, SP1
Hammerness, PG1
Briggs, AC1
Stretch, DD1
Brandon, S2
Tiffon, L1
Coplan, JD1
Papp, LA1
Gorman, JM1
Roberts, JM1
Malcolm, R1
Santos, AB1
Roth, M2
Weissman, M1
Lavori, P2
Gorman, J1
Rush, J1
Miyaoka, H1
Nozaki, S1
Kinami, Y1
Kamishima, K1
Massana, J1
Udina, C1
Ayuso, JL1
Cassano, GB3
Perugi, G1
Pecknold, JC2
Gelder, MG1
Clark, DM1
Salkovskis, P1
Woodman, CL1
Noyes, R3
Ballenger, JC7
Lydiard, RB3
Sievers, G1
Mihalko, D1
Toni, C2
Petracca, A1
Deltito, J1
Benkert, O2
Curtis, G1
Hippius, H1
Maier, W2
Shera, D2
Klerman, G1
Klerman, GL5
Goldenberg, I1
Olanoff, LS1
Sellers, EM2
von Moltke, LL1
Harmatz, JS3
Ciraulo, DA1
Cohon, MS1
Kravitz, HM1
Fawcett, J1
Newman, AJ1
Lavori, PW3
Goldenberg, IM1
Baker, LA1
Shear, K1
Schweizer, E4
Patterson, W1
Rosenthal, M1
Lepola, UM1
Rimón, RH1
Riekkinen, PJ1
Raj, AB2
Harnett-Sheehan, K2
Soto, S1
Knapp, E2
Tesar, GE1
Cohen, LS1
Meltzer-Brody, S2
Reiter, SR1
Greist, J1
Weiss, S2
Zavodnick, S2
Jolkkonen, J2
Lepola, U3
Bissette, G1
Nemeroff, C1
Riekkinen, P2
Munjack, DJ1
Brown, RA1
Cabe, DD1
McDowell, DE1
Baltazar, PL1
Shelton, RC1
Harvey, DS1
Stewart, PM1
Loosen, PT1
Dawson, R1
Diukova, GM1
Vorob'eva, OV1
Petrova, EP1
Smirnov, SV1
Tumalaeva, ZN1
Rimón, R1
Halonen, T1
Akiyoshi, J1
Moriyama, T1
Isogawa, K1
Miyamoto, M1
Sasaki, I1
Kuga, K1
Yamamoto, H1
Yamada, K1
Fujii, I1
Fava, GA1
Shioiri, T2
Fujii, K1
Someya, T1
Takahashi, S2
Koponen, H1
Leinonen, E1
Bond, AJ1
Bruce, MS1
Burrows, GD3
Reich, JH1
Judd, FK2
Garvey, MJ1
Norman, TR2
Cook, BL1
Marriott, P1
Kita, N1
Katschnig, H3
Amering, M3
Stolk, JM2
Briggs, A1
Buller, R4
Cassano, G1
Garvey, M1
Hetem, LA1
Zinder, O1
Zilberman, I2
Levy, N1
Greenberg, A1
Matsubayashi, S1
Tamaí, H1
Matsumoto, Y1
Tamagawa, K1
Mukuta, T1
Morita, T1
Kubo, C1
Pols, H1
Verburg, K1
Hauzer, R1
Meijer, J1
Griez, E1
Pollock, RA1
Gold, PW1
Davidson, JR1
Barlow, DH1
Olfson, M1
Warner, TD1
Thompson, PM1
Dorotheo, J1
Sheehan, MF1
Trehan, R1
Swiontek, A1
Coleman, B1
Roache, JD2
Stanley, MA1
Creson, DR1
Shah, NN1
Meisch, RA1
Livanou, M1
Wilhelm, FH1
Roth, WT2
Malel, D1
Biron, CR1
Shalev, AY1
Bloch, M1
Peri, T1
Bonne, O1
Matthews, J1
Scott, EL1
Fukuda, M1
Takazawa, S1
Nakagome, K1
Iwanami, A1
Hata, A1
Kasai, K1
Hiramatsu, K1
Hegel, MT1
Sheikh, JI1
Swales, PJ1
Lowell, K1
Rheinheimer, D1
Oswald, LM1
Rhoades, HM1
Kaplan, GB1
Ehrenberg, BL1
Goddard, JE1
Gladsjo, JA1
Rapaport, MH1
McKinney, R1
Auerbach, M1
Hahn, T1
Rabin, A1
Oliver, T1
Haze, A1
Judd, LL1
Sandyk, R1
Dann, LC1
Trochim, WM1
Cappelleri, JC1
Battaglia, M1
Sciuto, G1
Diaferia, G1
Petraglia, F1
León, CA1
Arévalo, W1
Gaviria, LF1
Sengün, S1
McCann, UD1
Ricaurte, GA1
Van Gool, D1
Igodt, P1
De Cuyper, H1
Hommer, D1
Kramer, GL1
Petty, F1
Watts-Jones, D1
Lesser, IM2
Antal, E1
Rubin, RT3
DuPont, R2
Scheibe, G1
Nutzinger, D1
Walther, AU1
Romach, MK1
Somer, GR1
Sobell, LC1
Sobell, MB1
Kaplan, HL1
DuPont, RL1
Rifkin, A1
Cox, BJ1
Endler, NS1
Lee, PS1
Albus, M1
Zahn, TP1
Breier, A1
Musetti, L1
van Balkom, AJ1
van Dyck, R1
Oosterbaan, D1
Margraf, J1
Ehlers, A1
Haddad, JM1
Maddock, RJ1
Agras, WS1
Taylor, CB1
Woods, SW1
Nagy, LM1
Koleszar, AS1
Krystal, JH1
Heninger, GR1
Charney, DS1
Laraia, M1
Korn, ML1
Kotler, M1
Molcho, A1
Botsis, AJ1
Grosz, D1
Chen, C1
Plutchik, R1
Brown, SL1
van Praag, HM1
Glod, CA1
Martin, T1
Winter, P1
Bowden, CL1
Ravaris, CL1
Friedman, MJ1
Hauri, PJ1
McHugo, GJ1
Roth, SM1
Argyle, N2
Ross, CA1
Clark, DB1
Solyom, C1
Solyom, L1
Saran, A1
Halaris, A1

Clinical Trials (6)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Role of Orexin in Human Panic Disorder[NCT02593682]Phase 43 participants (Actual)Interventional2016-05-31Completed
Searching for Exosomal microRNAs and Cellular Biomarkers and Mechanisms Underlying the Differences Between Panic Disorder Patients Who Are Responders and Non-responders to Cognitive Behavior Therapy[NCT04029740]80 participants (Anticipated)Interventional2019-03-24Recruiting
[NCT00004373]Phase 280 participants Interventional1997-03-31Completed
Age-based Cut-off Point as Methodological Approach in Search for Differences in Mortality and Revision for Fixation Type: Cemented Versus Uncemented Total Hip Arthroplasty[NCT05108155]43,789 participants (Actual)Observational [Patient Registry]2007-01-31Completed
Patient-centered Treatment of Anxiety After Low-Risk Chest Pain in the Emergency Room[NCT04811521]375 participants (Anticipated)Interventional2021-04-01Enrolling by invitation
Cognitive Remediation for Neuropsychological Impairment in Compulsive Hoarding[NCT01451697]Early Phase 120 participants (Anticipated)Interventional2011-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

27 reviews available for alprazolam and Panic Disorder

ArticleYear
Pharmacological treatments in panic disorder in adults: a network meta-analysis.
    The Cochrane database of systematic reviews, 2023, 11-28, Volume: 11

    Topics: Adult; Alprazolam; Antidepressive Agents; Antidepressive Agents, Tricyclic; Benzodiazepines; Clomipr

2023
The efficacy and safety of alprazolam versus other benzodiazepines in the treatment of panic disorder.
    Journal of clinical psychopharmacology, 2011, Volume: 31, Issue:5

    Topics: Agoraphobia; Alprazolam; Anti-Anxiety Agents; Benzodiazepines; Humans; Panic Disorder; Psychiatric S

2011
Treatment strategies of obsessive-compulsive disorder and panic disorder/agoraphobia.
    Current topics in medicinal chemistry, 2012, Volume: 12, Issue:4

    Topics: Agoraphobia; Alprazolam; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Clomipramine; Cognit

2012
Experimental panic provocation in healthy man-a translational role in anti-panic drug development?
    Dialogues in clinical neuroscience, 2011, Volume: 13, Issue:4

    Topics: Alprazolam; Anti-Anxiety Agents; Clinical Trials as Topic; Drug Design; Humans; Panic Disorder; Tetr

2011
The role of alprazolam for the treatment of panic disorder in Australia.
    The Australian and New Zealand journal of psychiatry, 2012, Volume: 46, Issue:3

    Topics: Alprazolam; Anti-Anxiety Agents; Australia; Controlled Clinical Trials as Topic; Guideline Adherence

2012
The management of panic disorder.
    The Journal of clinical psychiatry, 2002, Volume: 63 Suppl 14

    Topics: Alprazolam; Antidepressive Agents, Tricyclic; Benzodiazepines; Clinical Trials as Topic; Delayed-Act

2002
[Panic attacks and panic disorder. Checklist for the diagnosis].
    MMW Fortschritte der Medizin, 2003, May-26, Volume: 145 Suppl 2

    Topics: Adult; Alprazolam; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Antidepressive Age

2003
Clinical pharmacology, clinical efficacy, and behavioral toxicity of alprazolam: a review of the literature.
    CNS drug reviews, 2004,Spring, Volume: 10, Issue:1

    Topics: Alprazolam; Animals; Anti-Anxiety Agents; Anxiety Disorders; Automobile Driving; Behavior; Clinical

2004
Serotonin uptake inhibitors are superior to imipramine and alprazolam in alleviating panic attacks: a meta-analysis.
    International clinical psychopharmacology, 1995, Volume: 10, Issue:1

    Topics: Alprazolam; Double-Blind Method; Humans; Imipramine; Panic Disorder; Prospective Studies; Psychiatri

1995
Pure sleep panic: two case reports and a review of the literature.
    Sleep, 1994, Volume: 17, Issue:5

    Topics: Adult; Alcoholism; Alprazolam; Arousal; Combined Modality Therapy; Depressive Disorder; Female; Huma

1994
Drug treatment of panic disorder.
    Pharmacology & toxicology, 1993, Volume: 72, Issue:6

    Topics: Alprazolam; Anti-Anxiety Agents; Antidepressive Agents; Humans; Imipramine; Panic Disorder

1993
Cognitive treatment for panic disorder.
    Journal of psychiatric research, 1993, Volume: 27 Suppl 1

    Topics: Alprazolam; Arousal; Clinical Trials as Topic; Cognitive Behavioral Therapy; Humans; Imipramine; Pan

1993
Medication discontinuation in panic disorder.
    The Journal of clinical psychiatry, 1993, Volume: 54 Suppl

    Topics: Alprazolam; Benzodiazepines; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Admini

1993
Alprazolam pharmacokinetics, metabolism, and plasma levels: clinical implications.
    The Journal of clinical psychiatry, 1993, Volume: 54 Suppl

    Topics: Alprazolam; Anxiety Disorders; Biotransformation; Clinical Trials as Topic; Cytochrome P-450 Enzyme

1993
A comparison of the safety and efficacy of alprazolam versus other agents in the treatment of anxiety, panic, and depression: a review of the literature.
    The Journal of clinical psychiatry, 1993, Volume: 54 Suppl

    Topics: Alprazolam; Antidepressive Agents; Anxiety Disorders; Benzodiazepines; Buspirone; Clinical Trials as

1993
Alprazolam and depression: a review of risks and benefits.
    The Journal of clinical psychiatry, 1993, Volume: 54 Suppl

    Topics: Adolescent; Adult; Aged; Alprazolam; Benzodiazepines; Clinical Trials as Topic; Depressive Disorder;

1993
Clinical issues in the long-term treatment of panic disorder.
    The Journal of clinical psychiatry, 1996, Volume: 57 Suppl 10

    Topics: Age Factors; Agoraphobia; Alprazolam; Anti-Anxiety Agents; Antidepressive Agents; Child; Cognitive B

1996
Use of benzodiazepines in panic disorder.
    The Journal of clinical psychiatry, 1997, Volume: 58 Suppl 2

    Topics: Alprazolam; Benzodiazepines; Clonazepam; Humans; Lorazepam; Panic Disorder; Treatment Outcome

1997
Cognitive-behavioral therapy for panic disorder: current status.
    The Journal of clinical psychiatry, 1997, Volume: 58 Suppl 2

    Topics: Alprazolam; Cognitive Behavioral Therapy; Combined Modality Therapy; Controlled Clinical Trials as T

1997
Issues in the assessment of treatment response in panic disorder with special reference to fluvoxamine.
    The Journal of clinical psychiatry, 1997, Volume: 58 Suppl 5

    Topics: Alprazolam; Behavior Therapy; Clinical Trials as Topic; Cognitive Behavioral Therapy; Combined Modal

1997
Efficacy studies of alprazolam in panic disorder.
    Psychopharmacology bulletin, 1998, Volume: 34, Issue:2

    Topics: Alprazolam; Anti-Anxiety Agents; Clinical Trials as Topic; Humans; Panic Disorder

1998
Panic disorder: long-term pharmacotherapy and discontinuation.
    Journal of clinical psychopharmacology, 1998, Volume: 18, Issue:6 Suppl 2

    Topics: Alprazolam; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Chronic Disease; Controlled Clini

1998
Mode of action of the triazolobenzodiazepines in the treatment of panic attacks: a hypothesis.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1992, Volume: 2, Issue:4

    Topics: Alprazolam; Anti-Anxiety Agents; Humans; Panic Disorder

1992
Pharmacological and behavioural treatment of panic disorder.
    Psychotherapy and psychosomatics, 1992, Volume: 58, Issue:2

    Topics: Agoraphobia; Alprazolam; Humans; Panic Disorder

1992
[Benzodiazepines as pharmacotherapeutic possibility in the treatment of panic disorders].
    Nederlands tijdschrift voor geneeskunde, 1992, Feb-29, Volume: 136, Issue:9

    Topics: Alprazolam; Antidepressive Agents; Benzodiazepines; Clinical Trials as Topic; Double-Blind Method; H

1992
Xanax: pros and cons.
    Journal of psychosocial nursing and mental health services, 1992, Volume: 30, Issue:6

    Topics: Adult; Alprazolam; Anxiety Disorders; Depressive Disorder; Female; Humans; Panic Disorder; Stress Di

1992
Psychopharmacological treatment of panic disorder.
    Bulletin of the Menninger Clinic, 1992,Spring, Volume: 56, Issue:2 Suppl A

    Topics: Adult; Alprazolam; Antidepressive Agents, Tricyclic; Benzodiazepines; Depressive Disorder; Female; H

1992

Trials

88 trials available for alprazolam and Panic Disorder

ArticleYear
A comparison of the effects of a subtype selective and non-selective benzodiazepine receptor agonist in two CO(2) models of experimental human anxiety.
    Journal of psychopharmacology (Oxford, England), 2009, Volume: 23, Issue:2

    Topics: Administration, Inhalation; Adolescent; Adult; Alprazolam; Anti-Anxiety Agents; Anxiety Disorders; C

2009
Translocator protein (18 kD) as target for anxiolytics without benzodiazepine-like side effects.
    Science (New York, N.Y.), 2009, Jul-24, Volume: 325, Issue:5939

    Topics: Adult; Alprazolam; Animals; Anti-Anxiety Agents; Benzodiazepines; Cell Line; Drug Tolerance; gamma-A

2009
Efficacy of CBT for benzodiazepine discontinuation in patients with panic disorder: Further evaluation.
    Behaviour research and therapy, 2010, Volume: 48, Issue:8

    Topics: Adult; Alprazolam; Benzodiazepines; Clonazepam; Cognitive Behavioral Therapy; Dose-Response Relation

2010
Personality and symptom sensitivity predictors of alprazolam withdrawal in panic disorder.
    Psychological medicine, 2003, Volume: 33, Issue:3

    Topics: Adult; Alprazolam; Anti-Anxiety Agents; Dose-Response Relationship, Drug; Female; Humans; Male; Pani

2003
A 15-year follow-up study of patients with panic disorder.
    European psychiatry : the journal of the Association of European Psychiatrists, 2003, Volume: 18, Issue:8

    Topics: Activities of Daily Living; Agoraphobia; Alprazolam; Anti-Anxiety Agents; Antidepressive Agents, Sec

2003
Alprazolam extended-release in panic disorder.
    Expert opinion on pharmacotherapy, 2004, Volume: 5, Issue:7

    Topics: Alprazolam; Clinical Trials as Topic; Cross-Over Studies; Delayed-Action Preparations; Double-Blind

2004
Twenty-four hour growth hormone secretion in patients with panic disorder.
    Psychoneuroendocrinology, 2005, Volume: 30, Issue:1

    Topics: Adult; Alprazolam; Anti-Anxiety Agents; Circadian Rhythm; Female; Human Growth Hormone; Humans; Hypo

2005
Sertraline and alprazolam in the treatment of panic desorder.
    Bosnian journal of basic medical sciences, 2005, Volume: 5, Issue:2

    Topics: Adult; Alprazolam; Anti-Anxiety Agents; Drug Therapy, Combination; Female; Follow-Up Studies; Humans

2005
Effects of group experiential cognitive therapy for the treatment of panic disorder with agoraphobia.
    Cyberpsychology & behavior : the impact of the Internet, multimedia and virtual reality on behavior and society, 2005, Volume: 8, Issue:4

    Topics: Adult; Agoraphobia; Alprazolam; Anti-Anxiety Agents; Anticonvulsants; Clonazepam; Cognitive Behavior

2005
Influence of personality disorder on the treatment of panic disorder--comparison study.
    Neuro endocrinology letters, 2005, Volume: 26, Issue:6

    Topics: Adult; Agoraphobia; Alprazolam; Anti-Anxiety Agents; Cognitive Behavioral Therapy; Combined Modality

2005
Psychopathology of panic attacks in panic disorder.
    Journal of affective disorders, 2006, Volume: 92, Issue:1

    Topics: Agoraphobia; Alprazolam; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Cognition; Humans; I

2006
Abrupt discontinuation of alprazolam and cognitive style in patients with panic disorder: early effects on mood, performance, and vital signs.
    Journal of clinical psychopharmacology, 2006, Volume: 26, Issue:5

    Topics: Adolescent; Adult; Affect; Alprazolam; Anti-Anxiety Agents; Blood Pressure; Cognition; Cognitive Beh

2006
Anxiolytic therapy with alprazolam increases muscle sympathetic activity in patients with panic disorders.
    Autonomic neuroscience : basic & clinical, 2007, Jul-31, Volume: 134, Issue:1-2

    Topics: Adult; Alprazolam; Anti-Anxiety Agents; Blood Pressure; Female; Heart Rate; Humans; Male; Middle Age

2007
The speed of onset of action of alprazolam-XR compared to alprazolam-CT in panic disorder.
    Psychopharmacology bulletin, 2007, Volume: 40, Issue:2

    Topics: Adult; Agoraphobia; Alprazolam; Anti-Anxiety Agents; Biological Availability; Cross-Over Studies; De

2007
Pattern of placebo response in panic disorder.
    Psychopharmacology bulletin, 1995, Volume: 31, Issue:2

    Topics: Alprazolam; Follow-Up Studies; Humans; Imipramine; Panic Disorder; Placebo Effect; Time Factors; Tre

1995
Safety and side-effects of alprazolam. Controlled study in agoraphobia with panic disorder.
    The British journal of psychiatry : the journal of mental science, 1994, Volume: 165, Issue:1

    Topics: Adult; Agoraphobia; Alprazolam; Combined Modality Therapy; Desensitization, Psychologic; Dose-Respon

1994
A double-blind, placebo-controlled, multicenter study with alprazolam and extended-release alprazolam in the treatment of panic disorder.
    Journal of clinical psychopharmacology, 1994, Volume: 14, Issue:5

    Topics: Adult; Alprazolam; Arousal; Delayed-Action Preparations; Dose-Response Relationship, Drug; Double-Bl

1994
Alpha 2-adrenergic receptor sensitivity in panic disorder: I. GH response to GHRH and clonidine stimulation in panic disorder.
    Psychoneuroendocrinology, 1995, Volume: 20, Issue:1

    Topics: Adult; Agoraphobia; Alprazolam; Clonidine; Female; Growth Hormone; Growth Hormone-Releasing Hormone;

1995
Alpha 2-adrenergic receptor sensitivity in panic disorder: II. Cortisol response to clonidine stimulation in panic disorder.
    Psychoneuroendocrinology, 1995, Volume: 20, Issue:1

    Topics: Adult; Agoraphobia; Alprazolam; Clonidine; Female; Humans; Hydrocortisone; Male; Middle Aged; Panic

1995
Memory functions, alprazolam and exposure therapy: a controlled longitudinal study of agoraphobia with panic disorder.
    Psychological medicine, 1994, Volume: 24, Issue:4

    Topics: Adult; Affect; Agoraphobia; Alprazolam; Arousal; Combined Modality Therapy; Desensitization, Psychol

1994
Panic disorder with agoraphobia.
    The British journal of psychiatry : the journal of mental science, 1993, Volume: 163

    Topics: Agoraphobia; Alprazolam; Combined Modality Therapy; Desensitization, Psychologic; Humans; Panic Diso

1993
Pre-treatment predictors of treatment outcome in panic disorder and agoraphobia treated with alprazolam and exposure.
    Journal of affective disorders, 1994, Volume: 30, Issue:2

    Topics: Adult; Agoraphobia; Alprazolam; Combined Modality Therapy; Depressive Disorder; Desensitization, Psy

1994
Relationship of panic, anticipatory anxiety, agoraphobia and global improvement in panic disorder with agoraphobia treated with alprazolam and exposure.
    The British journal of psychiatry : the journal of mental science, 1994, Volume: 164, Issue:5

    Topics: Adult; Agoraphobia; Alprazolam; Anxiety Disorders; Arousal; Combined Modality Therapy; Desensitizati

1994
Alprazolam and exposure for panic disorder with agoraphobia. Attribution of improvement to medication predicts subsequent relapse.
    The British journal of psychiatry : the journal of mental science, 1994, Volume: 164, Issue:5

    Topics: Adult; Agoraphobia; Alprazolam; Arousal; Combined Modality Therapy; Desensitization, Psychologic; Fe

1994
Three years follow-up of panic disorder patients: a naturalistic study.
    Scandinavian journal of psychology, 1994, Volume: 35, Issue:3

    Topics: Adult; Alprazolam; Analysis of Variance; Chronic Disease; Female; Follow-Up Studies; Humans; Imipram

1994
The relationship of alprazolam and clonazepam dose to steady-state concentration in plasma.
    Journal of clinical psychopharmacology, 1994, Volume: 14, Issue:4

    Topics: Adolescent; Adult; Alprazolam; Clonazepam; Dose-Response Relationship, Drug; Double-Blind Method; Dr

1994
Alprazolam withdrawal in patients with panic disorder and generalized anxiety disorder: vulnerability and effect of carbamazepine.
    The American journal of psychiatry, 1994, Volume: 151, Issue:12

    Topics: Adult; Alprazolam; Anxiety Disorders; Carbamazepine; Double-Blind Method; Drug Administration Schedu

1994
Anxiety psychopathology predictive of outcome in patients with panic disorder and depression treated with imipramine, alprazolam and placebo.
    Journal of affective disorders, 1994, Volume: 30, Issue:4

    Topics: Adult; Aged; Alprazolam; Comorbidity; Depressive Disorder; Double-Blind Method; Female; Humans; Imip

1994
Alprazolam blockade of CO2-provoked panic in patients with panic disorder.
    The American journal of psychiatry, 1994, Volume: 151, Issue:8

    Topics: Administration, Inhalation; Adult; Alprazolam; Carbon Dioxide; Dose-Response Relationship, Drug; Dou

1994
Cognitive behavior therapy for treatment-refractory panic disorder.
    The Journal of clinical psychiatry, 1994, Volume: 55, Issue:5

    Topics: Adult; Alprazolam; Clonazepam; Cognitive Behavioral Therapy; Combined Modality Therapy; Female; Fluo

1994
Subtyping of panic disorder by symptom profile.
    The British journal of psychiatry : the journal of mental science, 1993, Volume: 163

    Topics: Adult; Alprazolam; Colombia; Europe; Female; Humans; Imipramine; Interview, Psychological; Linear Mo

1993
Comment on the London/Toronto Study of Alprazolam and Exposure in Panic Disorder with Agoraphobia.
    The British journal of psychiatry : the journal of mental science, 1993, Volume: 162

    Topics: Adolescent; Adult; Aged; Agoraphobia; Alprazolam; Combined Modality Therapy; Desensitization, Psycho

1993
Maintenance drug therapy of panic disorder.
    Journal of psychiatric research, 1993, Volume: 27 Suppl 1

    Topics: Agoraphobia; Alprazolam; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Imipramine;

1993
Discontinuation reactions to alprazolam in panic disorder.
    Journal of psychiatric research, 1993, Volume: 27 Suppl 1

    Topics: Agoraphobia; Alprazolam; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Adminis

1993
Predictors of response to alprazolam and placebo in patients with panic disorder.
    Journal of affective disorders, 1994, Volume: 30, Issue:1

    Topics: Adult; Alprazolam; Arousal; Double-Blind Method; Female; Humans; Male; Middle Aged; Panic Disorder;

1994
Does cognitive behavior therapy assist slow-taper alprazolam discontinuation in panic disorder?
    The American journal of psychiatry, 1994, Volume: 151, Issue:6

    Topics: Adult; Alprazolam; Ambulatory Care; Cognitive Behavioral Therapy; Combined Modality Therapy; Drug Ad

1994
Adverse effects associated with the short-term treatment of panic disorder with imipramine, alprazolam or placebo.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1994, Volume: 4, Issue:1

    Topics: Adolescent; Adult; Aged; Alprazolam; Double-Blind Method; Humans; Imipramine; Middle Aged; Panic Dis

1994
A comparison of symptom determinants of patient and clinician global ratings in patients with panic disorder and depression.
    Journal of clinical psychopharmacology, 1993, Volume: 13, Issue:5

    Topics: Adult; Aged; Alprazolam; Depressive Disorder; Double-Blind Method; Female; Humans; Imipramine; Male;

1993
Upjohn answers Consumer Reports.
    Journal of clinical psychopharmacology, 1993, Volume: 13, Issue:5

    Topics: Adverse Drug Reaction Reporting Systems; Alprazolam; Anxiety Disorders; Drug Industry; Humans; Panic

1993
Influence of depression on the treatment of panic disorder with imipramine, alprazolam and placebo.
    Journal of affective disorders, 1993, Volume: 28, Issue:1

    Topics: Adult; Aged; Alprazolam; Arousal; Depressive Disorder; Double-Blind Method; Female; Humans; Imiprami

1993
Double-blind, placebo-controlled study of a once-a-day, sustained-release preparation of alprazolam for the treatment of panic disorder.
    The American journal of psychiatry, 1993, Volume: 150, Issue:8

    Topics: Administration, Oral; Adolescent; Adult; Alprazolam; Delayed-Action Preparations; Double-Blind Metho

1993
Three-year follow-up of patients with panic disorder after short-term treatment with alprazolam and imipramine.
    International clinical psychopharmacology, 1993,Summer, Volume: 8, Issue:2

    Topics: Adolescent; Adult; Agoraphobia; Alprazolam; Dose-Response Relationship, Drug; Double-Blind Method; D

1993
Plasma alprazolam concentrations. Relation to efficacy and side effects in the treatment of panic disorder.
    Archives of general psychiatry, 1993, Volume: 50, Issue:9

    Topics: Adolescent; Adult; Agoraphobia; Alprazolam; Dose-Response Relationship, Drug; Double-Blind Method; D

1993
Long-term outcome after acute treatment with alprazolam or clonazepam for panic disorder.
    Journal of clinical psychopharmacology, 1993, Volume: 13, Issue:4

    Topics: Adult; Alprazolam; Clonazepam; Double-Blind Method; Female; Follow-Up Studies; Humans; Male; Panic D

1993
Discontinuation of benzodiazepine treatment: efficacy of cognitive-behavioral therapy for patients with panic disorder.
    The American journal of psychiatry, 1993, Volume: 150, Issue:10

    Topics: Adult; Alprazolam; Ambulatory Care; Benzodiazepines; Clonazepam; Cognitive Behavioral Therapy; Combi

1993
Drug treatment of panic disorder. Further comment.
    The British journal of psychiatry : the journal of mental science, 1993, Volume: 162

    Topics: Alprazolam; Bias; Combined Modality Therapy; Follow-Up Studies; Humans; Panic Disorder; Psychotherap

1993
Maintenance drug treatment of panic disorder. I. Results of a prospective, placebo-controlled comparison of alprazolam and imipramine.
    Archives of general psychiatry, 1993, Volume: 50, Issue:1

    Topics: Adult; Agoraphobia; Alprazolam; Anxiety Disorders; Dose-Response Relationship, Drug; Double-Blind Me

1993
Maintenance drug treatment for panic disorder. II. Short- and long-term outcome after drug taper.
    Archives of general psychiatry, 1993, Volume: 50, Issue:1

    Topics: Adult; Alprazolam; Ambulatory Care; Dose-Response Relationship, Drug; Double-Blind Method; Drug Admi

1993
A multiple imputation strategy for clinical trials with truncation of patient data.
    Statistics in medicine, 1995, Sep-15, Volume: 14, Issue:17

    Topics: Adult; Alprazolam; Ambulatory Care; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Bayes The

1995
[The efficacy of alprazolam in the therapy of panic disorders].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 1995, Volume: 95, Issue:4

    Topics: Adolescent; Adult; Alprazolam; Anti-Anxiety Agents; Female; Humans; Male; Middle Aged; Panic Disorde

1995
Cerebrospinal fluid gamma-aminobutyric acid in patients with panic disorder.
    Biological psychiatry, 1995, Dec-01, Volume: 38, Issue:11

    Topics: Adult; Alprazolam; Antidepressive Agents, Tricyclic; Female; GABA Modulators; gamma-Aminobutyric Aci

1995
Effect of pharmacotherapy on serum cholesterol levels in patients with panic disorder.
    Acta psychiatrica Scandinavica, 1996, Volume: 93, Issue:3

    Topics: Adult; Agoraphobia; Alprazolam; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Antipsychotic

1996
Behavioural aggression in panic disorder after 8 weeks' treatment with alprazolam.
    Journal of affective disorders, 1995, Dec-13, Volume: 35, Issue:3

    Topics: Adult; Aggression; Agoraphobia; Alprazolam; Anti-Anxiety Agents; Arousal; Competitive Behavior; Doub

1995
Diazepam versus alprazolam for the treatment of panic disorder.
    The Journal of clinical psychiatry, 1996, Volume: 57, Issue:8

    Topics: Adult; Age of Onset; Alprazolam; Diazepam; Double-Blind Method; Drug Administration Schedule; Female

1996
Long-term follow-up after a drug trial for panic disorder.
    The British journal of psychiatry : the journal of mental science, 1995, Volume: 167, Issue:4

    Topics: Adolescent; Adult; Aged; Alprazolam; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Dose-Res

1995
Alprazolam premedication and 35% carbon dioxide vulnerability in panic patients.
    Biological psychiatry, 1996, Nov-01, Volume: 40, Issue:9

    Topics: Adult; Agoraphobia; Alprazolam; Anti-Anxiety Agents; Arousal; Carbon Dioxide; Cross-Over Studies; Do

1996
Predictors of quality of life in a long-term followup study in panic disorder patients after a clinical drug trial.
    Psychopharmacology bulletin, 1996, Volume: 32, Issue:1

    Topics: Alprazolam; Follow-Up Studies; Humans; Imipramine; Panic Disorder; Prognosis; Prospective Studies; Q

1996
Service utilization and expenditures for the treatment of panic disorder.
    General hospital psychiatry, 1997, Volume: 19, Issue:2

    Topics: Adult; Alprazolam; Ambulatory Care; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Community

1997
Growing placebo response rate: the problem in recent therapeutic trials?
    Psychopharmacology bulletin, 1997, Volume: 33, Issue:1

    Topics: Alprazolam; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Double-

1997
Alprazolam-reinforced medication use in outpatients with anxiety.
    Drug and alcohol dependence, 1997, May-02, Volume: 45, Issue:3

    Topics: Adult; Alprazolam; Analysis of Variance; Anti-Anxiety Agents; Anxiety Disorders; Behavior, Addictive

1997
Double-blindness procedures, rater blindness, and ratings of outcome. Observations from a controlled trial.
    Archives of general psychiatry, 1997, Volume: 54, Issue:8

    Topics: Agoraphobia; Alprazolam; Combined Modality Therapy; Double-Blind Method; Drug Administration Schedul

1997
Acute and delayed effects of alprazolam on flight phobics during exposure.
    Behaviour research and therapy, 1997, Volume: 35, Issue:9

    Topics: Adult; Aircraft; Alprazolam; Analysis of Variance; Anti-Anxiety Agents; Anxiety; Case-Control Studie

1997
Subjective experience and attitudes towards participation in clinical trials among patients with anxiety disorders.
    The Israel journal of psychiatry and related sciences, 1997, Volume: 34, Issue:4

    Topics: Adult; Alprazolam; Anti-Anxiety Agents; Anxiety Disorders; Female; Humans; Male; Panic Disorder; Pat

1997
Panic disorder: long-term pharmacotherapy and discontinuation.
    Journal of clinical psychopharmacology, 1998, Volume: 18, Issue:6 Suppl 2

    Topics: Alprazolam; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Chronic Disease; Controlled Clini

1998
Cognitive-behavioral therapy helps prevent relapse and recurrence of panic disorder following alprazolam discontinuation: a long-term follow-up of the Peoria and Dartmouth studies.
    Journal of consulting and clinical psychology, 1999, Volume: 67, Issue:1

    Topics: Alprazolam; Benzodiazepines; Cognitive Behavioral Therapy; Combined Modality Therapy; Female; Follow

1999
Long-term effects of alprazolam on memory: a 3.5 year follow-up of agoraphobia/panic patients.
    Psychological medicine, 1999, Volume: 29, Issue:1

    Topics: Adult; Agoraphobia; Alprazolam; Anti-Anxiety Agents; Female; Follow-Up Studies; Humans; Male; Memory

1999
Treatment of panic disorder in older adults: a pilot study comparison of alprazolam, imipramine, and placebo.
    International journal of psychiatry in medicine, 1999, Volume: 29, Issue:1

    Topics: Aged; Alprazolam; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Dose-Response Relationship,

1999
A strategy to evaluate a covariate by group interaction in an analysis of covariance.
    Psychopharmacology bulletin, 1998, Volume: 34, Issue:4

    Topics: Alprazolam; Analysis of Variance; Anti-Anxiety Agents; Data Interpretation, Statistical; Humans; Mod

1998
Predictors of individual differences in alprazolam self-medication.
    Experimental and clinical psychopharmacology, 1999, Volume: 7, Issue:4

    Topics: Adult; Affect; Alprazolam; Anti-Anxiety Agents; Anxiety Disorders; Double-Blind Method; Female; Huma

1999
Differences in pharmacodynamics but not pharmacokinetics between subjects with panic disorder and healthy subjects after treatment with a single dose of alprazolam.
    Journal of clinical psychopharmacology, 2000, Volume: 20, Issue:3

    Topics: Adult; Alprazolam; Anti-Anxiety Agents; Cross-Over Studies; Double-Blind Method; Electroencephalogra

2000
Absence of neuropsychologic deficits in patients receiving long-term treatment with alprazolam-XR for panic disorder.
    Journal of clinical psychopharmacology, 2001, Volume: 21, Issue:2

    Topics: Adult; Alprazolam; Analysis of Variance; Anti-Anxiety Agents; Attention; Delayed-Action Preparations

2001
Drug treatment of panic disorder. Reply to comment by Marks and associates.
    The British journal of psychiatry : the journal of mental science, 1992, Volume: 161

    Topics: Agoraphobia; Alprazolam; Anxiety Disorders; Cross-Cultural Comparison; Dose-Response Relationship, D

1992
[Patients with panic disorder: a 5-year follow-up study].
    Acta psiquiatrica y psicologica de America latina, 1992, Volume: 38, Issue:4

    Topics: Adult; Alprazolam; Double-Blind Method; Female; Follow-Up Studies; Humans; Imipramine; Male; Middle

1992
Effect of acute and chronic benzodiazepines on plasma GABA in anxious patients and controls.
    Psychopharmacology, 1992, Volume: 109, Issue:1-2

    Topics: Adult; Alprazolam; Anti-Anxiety Agents; Anxiety Disorders; Diazepam; gamma-Aminobutyric Acid; Humans

1992
Alprazolam plasma concentrations and treatment response in panic disorder and agoraphobia.
    The American journal of psychiatry, 1992, Volume: 149, Issue:11

    Topics: Adult; Agoraphobia; Alprazolam; Clinical Protocols; Dose-Response Relationship, Drug; Double-Blind M

1992
Pretreatment anxiety level as differential predictor in outpatients with panic disorder.
    Arzneimittel-Forschung, 1992, Volume: 42, Issue:9

    Topics: Adult; Alprazolam; Anxiety; Female; Humans; Imipramine; Male; Outpatients; Panic Disorder; Prognosis

1992
Discontinuation of alprazolam after long-term treatment of panic-related disorders.
    Journal of clinical psychopharmacology, 1992, Volume: 12, Issue:5

    Topics: Adult; Alprazolam; Double-Blind Method; Drug Administration Schedule; Drug Tolerance; Female; Follow

1992
Anxiogenic properties of yohimbine. I. Behavioral, physiological and biochemical measures.
    European archives of psychiatry and clinical neuroscience, 1992, Volume: 241, Issue:6

    Topics: Adult; Agoraphobia; Alprazolam; Arousal; Female; Galvanic Skin Response; Heart Rate; Humans; Hydroco

1992
Treatment of panic disorder.
    Advances in biochemical psychopharmacology, 1992, Volume: 47

    Topics: Adult; Agoraphobia; Alprazolam; Double-Blind Method; Female; Humans; Imipramine; Male; Panic Disorde

1992
Drug treatment of panic disorder. Comparative efficacy of alprazolam, imipramine, and placebo. Cross-National Collaborative Panic Study, Second Phase Investigators.
    The British journal of psychiatry : the journal of mental science, 1992, Volume: 160

    Topics: Adult; Alprazolam; Cross-Sectional Studies; Double-Blind Method; Female; Humans; Imipramine; Neurops

1992
Imipramine and alprazolam effects on stress test reactivity in panic disorder.
    Biological psychiatry, 1992, Jan-01, Volume: 31, Issue:1

    Topics: Adult; Alprazolam; Anxiety; Arrhythmias, Cardiac; Blood Pressure; Carbon Dioxide; Cold Temperature;

1992
Controlled trial of alprazolam supplementation during imipramine treatment of panic disorder.
    Journal of clinical psychopharmacology, 1992, Volume: 12, Issue:1

    Topics: Adolescent; Adult; Aged; Alprazolam; Analysis of Variance; Double-Blind Method; Drug Therapy, Combin

1992
A fixed-dose study of alprazolam 2 mg, alprazolam 6 mg, and placebo in panic disorder.
    Journal of clinical psychopharmacology, 1992, Volume: 12, Issue:2

    Topics: Adolescent; Adult; Aged; Agoraphobia; Alprazolam; Arousal; Dose-Response Relationship, Drug; Double-

1992
Assessing impairment in patients with panic disorder: the Sheehan Disability Scale.
    Social psychiatry and psychiatric epidemiology, 1992, Volume: 27, Issue:2

    Topics: Activities of Daily Living; Adolescent; Adult; Aged; Alprazolam; Disability Evaluation; Double-Blind

1992
Assessing impairment in patients with panic disorder: the Sheehan Disability Scale.
    Social psychiatry and psychiatric epidemiology, 1992, Volume: 27, Issue:2

    Topics: Activities of Daily Living; Adolescent; Adult; Aged; Alprazolam; Disability Evaluation; Double-Blind

1992
Assessing impairment in patients with panic disorder: the Sheehan Disability Scale.
    Social psychiatry and psychiatric epidemiology, 1992, Volume: 27, Issue:2

    Topics: Activities of Daily Living; Adolescent; Adult; Aged; Alprazolam; Disability Evaluation; Double-Blind

1992
Assessing impairment in patients with panic disorder: the Sheehan Disability Scale.
    Social psychiatry and psychiatric epidemiology, 1992, Volume: 27, Issue:2

    Topics: Activities of Daily Living; Adolescent; Adult; Aged; Alprazolam; Disability Evaluation; Double-Blind

1992
Center differences and cross-national invariance in help-seeking for panic disorder. A report from the cross-national collaborative panic study.
    Social psychiatry and psychiatric epidemiology, 1992, Volume: 27, Issue:3

    Topics: Adult; Alprazolam; Cross-Cultural Comparison; Cross-Sectional Studies; Female; Humans; Imipramine; I

1992
A controlled study of alprazolam and propranolol in panic-disordered and agoraphobic outpatients.
    Journal of clinical psychopharmacology, 1991, Volume: 11, Issue:6

    Topics: Adolescent; Adult; Agoraphobia; Alprazolam; Double-Blind Method; Female; Humans; Male; Middle Aged;

1991
Avoidance behaviour: a predictor of the efficacy of pharmacotherapy in panic disorder?
    European archives of psychiatry and clinical neuroscience, 1991, Volume: 241, Issue:3

    Topics: Adult; Agoraphobia; Alprazolam; Arousal; Double-Blind Method; Fear; Female; Humans; Imipramine; Male

1991
The structure of phobias in panic disorder.
    The British journal of psychiatry : the journal of mental science, 1991, Volume: 159

    Topics: Adult; Agoraphobia; Alprazolam; Double-Blind Method; Female; Humans; Imipramine; Male; Middle Aged;

1991

Other Studies

76 other studies available for alprazolam and Panic Disorder

ArticleYear
Intravenous doxapram administration as a potential model of panic attacks in rats.
    Behavioural pharmacology, 2021, 04-01, Volume: 32, Issue:2&3

    Topics: Administration, Intravenous; Alprazolam; Animals; Benzamides; Carbamates; Central Nervous System Sti

2021
The Rodent-versus-wild Snake Paradigm as a Model for Studying Anxiety- and Panic-like Behaviors: Face, Construct and Predictive Validities.
    Neuroscience, 2018, 01-15, Volume: 369

    Topics: Alprazolam; Animals; Anti-Anxiety Agents; Anxiety; Dose-Response Relationship, Drug; Elapidae; Escap

2018
[Family malediction in the background of panic disorder -- case report].
    Psychiatria Hungarica : A Magyar Pszichiatriai Tarsasag tudomanyos folyoirata, 2013, Volume: 28, Issue:4

    Topics: Adult; Alprazolam; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Anxiety; Citalopra

2013
Pseudopheochromocytoma induced by anxiolytic withdrawal.
    European journal of medical research, 2014, Oct-08, Volume: 19

    Topics: Adrenal Gland Neoplasms; Alprazolam; Anti-Anxiety Agents; Female; Headache; Humans; Hypertension; Mi

2014
Effects of alprazolam and cannabinoid-related compounds in an animal model of panic attack.
    Behavioural brain research, 2017, 01-15, Volume: 317

    Topics: Alprazolam; Analgesics; Animals; Arachidonic Acids; Benzamides; Benzoxazines; Blood Pressure; Cannab

2017
A CASE OF ADVANCED NON-SEMINOMATOUS TESTICULAR GERM CELL TUMOR ACCOMPANIED PANIC DISORDER.
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 2016, Volume: 107, Issue:1

    Topics: Adult; alpha-Fetoproteins; Alprazolam; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, T

2016
Alprazolam prescribing in Tasmania: a two-fold intervention designed to reduce inappropriate prescribing and concomitant opiate prescription.
    Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists, 2009, Volume: 17, Issue:4

    Topics: Alprazolam; Analgesics, Opioid; Australia; Drug Prescriptions; Drug Utilization; Guidelines as Topic

2009
A key role for orexin in panic anxiety.
    Nature medicine, 2010, Volume: 16, Issue:1

    Topics: Adult; Alprazolam; Animals; Anxiety; Disease Models, Animal; Female; Humans; Hypothalamus; Intracell

2010
11-year-old boy with panic disorder responding to paroxetine.
    The Tokai journal of experimental and clinical medicine, 2007, Mar-20, Volume: 32, Issue:1

    Topics: Alprazolam; Anti-Anxiety Agents; Child; Humans; Male; Neuropsychological Tests; Panic Disorder; Paro

2007
Duloxetine-related panic attacks.
    Psychiatria Danubina, 2011, Volume: 23, Issue:1

    Topics: Alprazolam; Anti-Anxiety Agents; Antidepressive Agents; Antidepressive Agents, Tricyclic; Dose-Respo

2011
A latent class approach to the external validation of respiratory and non-respiratory panic subtypes.
    Psychological medicine, 2012, Volume: 42, Issue:3

    Topics: Age of Onset; Alprazolam; Anti-Anxiety Agents; Antidepressive Agents; Diagnostic and Statistical Man

2012
Reconsidering benzodiazepines in the treatment of panic disorder.
    The Australian and New Zealand journal of psychiatry, 2012, Volume: 46, Issue:3

    Topics: Alprazolam; Anti-Anxiety Agents; Humans; Panic Disorder

2012
Commentary on 'The role of alprazolam for the treatment of panic disorder in Australia'.
    The Australian and New Zealand journal of psychiatry, 2012, Volume: 46, Issue:3

    Topics: Alprazolam; Anti-Anxiety Agents; Humans; Panic Disorder

2012
Group II metabotropic glutamate receptor type 2 allosteric potentiators prevent sodium lactate-induced panic-like response in panic-vulnerable rats.
    Journal of psychopharmacology (Oxford, England), 2013, Volume: 27, Issue:2

    Topics: Alprazolam; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Cardiovascular System; gamma-Am

2013
Pharmacokinetically induced benzodiazepine withdrawal.
    Psychopharmacology bulletin, 2001,Autumn, Volume: 35, Issue:4

    Topics: Alprazolam; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Cyclohexanols; Drug Inter

2001
Panic disorder patients at the time of air strikes.
    Depression and anxiety, 2002, Volume: 16, Issue:4

    Topics: Adult; Agoraphobia; Aircraft; Alprazolam; Catchment Area, Health; Clonazepam; Female; Follow-Up Stud

2002
Xanax XR for panic disorder.
    The Medical letter on drugs and therapeutics, 2003, May-26, Volume: 45, Issue:1157

    Topics: Alprazolam; Anti-Anxiety Agents; Delayed-Action Preparations; Drug Interactions; Humans; Panic Disor

2003
[Clinical picture and treatment of agoraphobia with panic disorder].
    Voenno-meditsinskii zhurnal, 2003, Volume: 324, Issue:6

    Topics: Adult; Agoraphobia; Alprazolam; Anti-Anxiety Agents; Benzodiazepines; Humans; Middle Aged; Military

2003
Panic symptoms without report of anxiety.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2005, Volume: 44, Issue:5

    Topics: Adolescent; Alprazolam; Anti-Anxiety Agents; Anxiety; Child; Diagnostic and Statistical Manual of Me

2005
Trimipramine for refractory panic attacks.
    The American journal of psychiatry, 2006, Volume: 163, Issue:3

    Topics: Adult; Alprazolam; Antidepressive Agents, Tricyclic; Drug Resistance; Drug Therapy, Combination; Hum

2006
Prediction of anti-panic properties of escitalopram in the dorsal periaqueductal grey model of panic anxiety.
    Neuropharmacology, 2006, Volume: 51, Issue:1

    Topics: Adrenergic alpha-Antagonists; Alprazolam; Animals; Anxiety; Citalopram; Dose-Response Relationship,

2006
Effects of repetitive transcranial magnetic stimulation (rTMS) on panic attacks induced by cholecystokinin-tetrapeptide (CCK-4).
    The international journal of neuropsychopharmacology, 2007, Volume: 10, Issue:2

    Topics: Adrenocorticotropic Hormone; Adult; Alprazolam; Anti-Anxiety Agents; Area Under Curve; Female; Heart

2007
[Gabapentin treatment in a female patient with panic disorder and adverse effects under carbamazepine during benzodiazepine withdrawal].
    Psychiatrische Praxis, 2007, Volume: 34, Issue:2

    Topics: Aged; Alprazolam; Amines; Antimanic Agents; Benzodiazepines; Carbamazepine; Chemical and Drug Induce

2007
Medication management with panic disorder in the exercise state: some prescribing guidelines.
    CNS spectrums, 2007, Volume: 12, Issue:3

    Topics: Adult; Alprazolam; Anti-Anxiety Agents; Dose-Response Relationship, Drug; Drug Prescriptions; Exerci

2007
Cognitive style, alprazolam plasma levels, and treatment response in panic disorder.
    Depression and anxiety, 2008, Volume: 25, Issue:8

    Topics: Adolescent; Adult; Alprazolam; Anti-Anxiety Agents; Anxiety; Cognition; Depression; Diagnostic and S

2008
Citalopram-associated spontaneous ejaculations.
    Journal of clinical psychopharmacology, 2008, Volume: 28, Issue:3

    Topics: Adult; Alprazolam; Antidepressive Agents, Second-Generation; Citalopram; Depressive Disorder, Major;

2008
More reliable outcome measures can reduce sample size requirements.
    Archives of general psychiatry, 1995, Volume: 52, Issue:10

    Topics: Alprazolam; Depressive Disorder; Humans; Imipramine; Panic Disorder; Placebos; Psychiatric Status Ra

1995
Predictors of alprazolam discontinuation with and without cognitive behavior therapy in panic disorder.
    The American journal of psychiatry, 1995, Volume: 152, Issue:8

    Topics: Adult; Alprazolam; Cognitive Behavioral Therapy; Combined Modality Therapy; Drug Administration Sche

1995
Plasma interleukin-1 beta concentrations in panic disorder.
    Psychiatry research, 1994, Volume: 54, Issue:2

    Topics: Adult; Alprazolam; Amitriptyline; Antibodies, Monoclonal; Anxiety; Benzodiazepines; Cytokines; Femal

1994
Benzodiazepine sensitivity in panic disorder: effects of chronic alprazolam treatment.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1995, Volume: 12, Issue:2

    Topics: Adult; Alprazolam; Diazepam; Dose-Response Relationship, Drug; Drug Tolerance; Female; Growth Hormon

1995
Is there anything new on the use of psychotropic drugs during pregnancy?
    Journal of clinical psychopharmacology, 1994, Volume: 14, Issue:6

    Topics: Abnormalities, Drug-Induced; Adult; Alprazolam; Anti-Anxiety Agents; Female; Humans; Infant, Newborn

1994
Upjohn responds to Consumer Reports letter.
    Journal of clinical psychopharmacology, 1994, Volume: 14, Issue:4

    Topics: Alprazolam; Anxiety Disorders; Clinical Trials as Topic; Drug Industry; Drug Utilization; Humans; Pa

1994
Response to "high anxiety".
    Journal of clinical psychopharmacology, 1994, Volume: 14, Issue:4

    Topics: Alprazolam; Anxiety Disorders; Dose-Response Relationship, Drug; Female; Humans; Panic Disorder; Ris

1994
Role of panic attacks in the intractability of asthma in children.
    Pediatrics, 1994, Volume: 94, Issue:1

    Topics: Alprazolam; Asthma; Child, Preschool; Humans; Male; Panic Disorder

1994
Alprazolam utilisation in 1991.
    Australian family physician, 1994, Volume: 23, Issue:6

    Topics: Alprazolam; Humans; Panic Disorder

1994
Augmentation strategies with tricyclic or fluoxetine treatment in seven partially responsive panic disorder patients.
    The Journal of clinical psychiatry, 1994, Volume: 55, Issue:2

    Topics: Adult; Alprazolam; Antidepressive Agents, Tricyclic; Desipramine; Drug Therapy, Combination; Female;

1994
Treatment of panic disorder and comorbid substance abuse with divalproex sodium.
    The American journal of psychiatry, 1994, Volume: 151, Issue:10

    Topics: Adult; Alprazolam; Comorbidity; Humans; Male; Panic Disorder; Substance-Related Disorders; Treatment

1994
[Drug therapy of panic disorder and prediction of its therapeutic responses].
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 1993, Volume: 95, Issue:11

    Topics: Adult; Alprazolam; Female; Humans; Male; Panic Disorder; Prognosis

1993
Panic disorders and the listing of alprazolam on authority on the PBS. Beware of overdiagnosis.
    Australian family physician, 1994, Volume: 23, Issue:4

    Topics: Alprazolam; Diagnostic Errors; Humans; Panic Disorder

1994
Lymphocyte cholecystokinin concentrations in panic disorder.
    The American journal of psychiatry, 1993, Volume: 150, Issue:7

    Topics: Adolescent; Adult; Alprazolam; Child; Female; Humans; Lymphocytes; Male; Panic Disorder; Severity of

1993
The relative efficacy of high-dose buspirone and alprazolam in the treatment of panic disorder: a double-blind placebo-controlled study.
    Acta psychiatrica Scandinavica, 1993, Volume: 88, Issue:1

    Topics: Adolescent; Adult; Alprazolam; Benzodiazepines; Buspirone; Comorbidity; Depressive Disorder; Double-

1993
CSF corticotropin-releasing factor is not affected in panic disorder.
    Biological psychiatry, 1993, Jan-15, Volume: 33, Issue:2

    Topics: Adult; Alprazolam; Corticotropin-Releasing Hormone; Female; Humans; Male; Panic Disorder

1993
A naturalistic follow-up of panic patients after short-term pharmacologic treatment.
    Journal of clinical psychopharmacology, 1993, Volume: 13, Issue:2

    Topics: Adult; Alprazolam; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Male; Middle Age

1993
Alprazolam in panic disorder: a retrospective analysis.
    Progress in neuro-psychopharmacology & biological psychiatry, 1993, Volume: 17, Issue:3

    Topics: Adult; Agoraphobia; Alprazolam; Depressive Disorder; Female; Humans; Male; Panic Disorder; Psychiatr

1993
Hypothalamic-pituitary-adrenal axis activity in panic disorder: prediction of long-term outcome by pretreatment cortisol levels.
    The American journal of psychiatry, 1996, Volume: 153, Issue:1

    Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Alprazolam; Circadian Rhythm; Female; Follow-Up Stud

1996
CCK-4-induced calcium mobilization in T cells is enhanced in panic disorder.
    Journal of neurochemistry, 1996, Volume: 66, Issue:4

    Topics: Adult; Alprazolam; Biomarkers; Calcium; Dose-Response Relationship, Drug; Female; Humans; Male; Midd

1996
Anxiety sensitivity.
    The American journal of psychiatry, 1996, Volume: 153, Issue:8

    Topics: Agoraphobia; Alprazolam; Anxiety Disorders; Benzodiazepines; Cognitive Behavioral Therapy; Combined

1996
A naturalistic 6-year follow-up study of patients with panic disorder.
    Acta psychiatrica Scandinavica, 1996, Volume: 93, Issue:3

    Topics: Adult; Alcoholism; Alprazolam; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Comorbidity; D

1996
Two cases of alprazolam-induced hyperprolactinemia in patients with panic disorder.
    International clinical psychopharmacology, 1996, Volume: 11, Issue:2

    Topics: Adult; Alprazolam; Anti-Anxiety Agents; Female; Humans; Hyperprolactinemia; Middle Aged; Panic Disor

1996
Addition of d-fenfluramine to benzodiazepines produces a marked improvement in refractory panic disorder--a case report.
    Journal of clinical psychopharmacology, 1996, Volume: 16, Issue:1

    Topics: Adult; Alprazolam; Anti-Anxiety Agents; Clonazepam; Drug Resistance; Female; Fenfluramine; Humans; P

1996
Clinical similarity and biological diversity in the response to alprazolam in patients with panic disorder and generalized anxiety disorder.
    Acta psychiatrica Scandinavica, 1995, Volume: 92, Issue:6

    Topics: Adrenocorticotropic Hormone; Adult; Alprazolam; Anti-Anxiety Agents; Anxiety Disorders; Catecholamin

1995
Graves'disease after the onset of panic disorder.
    Psychotherapy and psychosomatics, 1996, Volume: 65, Issue:5

    Topics: Alprazolam; Anxiety Disorders; Benzodiazepines; Female; Graves Disease; Humans; Hyperthyroidism; Lif

1996
Adrenocorticotropic hormone and cortisol responses to corticotropin-releasing hormone: changes in panic disorder and effects of alprazolam treatment.
    Biological psychiatry, 1997, Jan-01, Volume: 41, Issue:1

    Topics: Adrenocorticotropic Hormone; Adult; Agoraphobia; Alprazolam; Anti-Anxiety Agents; Arousal; Corticotr

1997
Method for assessing the duration of therapeutic action and milligram equivalence of anxiolytics.
    Anxiety, 1996, Volume: 2, Issue:1

    Topics: Adolescent; Adult; Aged; Agoraphobia; Alprazolam; Anti-Anxiety Agents; Anxiety Disorders; Delayed-Ac

1996
Personality dimensions in panic disorder before and after effective treatment.
    Anxiety, 1996, Volume: 2, Issue:2

    Topics: Adult; Agoraphobia; Alprazolam; Anti-Anxiety Agents; Female; Humans; Male; Middle Aged; Panic Disord

1996
Agoraphobia and panic disorder: 3.5 years after alprazolam and/or exposure treatment.
    Psychotherapy and psychosomatics, 1997, Volume: 66, Issue:4

    Topics: Adult; Agoraphobia; Alprazolam; Anti-Anxiety Agents; Female; Follow-Up Studies; Humans; Male; Panic

1997
Calm response soothes patients' panic attacks, but nervousness needs to be addressed earlier.
    RDH, 1996, Volume: 16, Issue:11

    Topics: Adult; Alprazolam; Anti-Anxiety Agents; Dental Anxiety; Female; Humans; Panic Disorder

1996
Alprazolam reduces response to loud tones in panic disorder but not in posttraumatic stress disorder.
    Biological psychiatry, 1998, Jul-01, Volume: 44, Issue:1

    Topics: Acoustic Stimulation; Adult; Alprazolam; Arousal; Auditory Perception; Blinking; Diagnosis, Differen

1998
Gabapentin as a potential treatment for anxiety disorders.
    The American journal of psychiatry, 1998, Volume: 155, Issue:7

    Topics: Acetates; Adult; Alprazolam; Amines; Anticonvulsants; Anxiety Disorders; Cyclohexanecarboxylic Acids

1998
Decreased plasma cortisol level during alprazolam treatment of panic disorder: a case report.
    Progress in neuro-psychopharmacology & biological psychiatry, 1998, Volume: 22, Issue:5

    Topics: Adult; Alprazolam; Anti-Anxiety Agents; Dose-Response Relationship, Drug; Hormones; Humans; Hydrocor

1998
Experimental procedures and the placebo response.
    The Harvard mental health letter, 1998, Volume: 15, Issue:4

    Topics: Alprazolam; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Humans; Imipramine; Panic Disorde

1998
Plasma levels of tumor necrosis factor-alpha in patients with panic disorder: effect of alprazolam therapy.
    Psychiatry research, 1999, Dec-13, Volume: 89, Issue:1

    Topics: Adult; Agoraphobia; Alprazolam; Anti-Anxiety Agents; Female; Humans; Male; Middle Aged; Panic Disord

1999
Seasonal panic disorder: a possible variant of seasonal affective disorder.
    The International journal of neuroscience, 1992, Volume: 62, Issue:3-4

    Topics: Adult; Alprazolam; Anxiety Disorders; Circadian Rhythm; Combined Modality Therapy; Depressive Disord

1992
Cutoff assignment strategies for enhancing randomized clinical trials.
    Controlled clinical trials, 1992, Volume: 13, Issue:3

    Topics: Alprazolam; Bias; Ethics, Medical; Humans; Models, Statistical; Panic Disorder; Personality Inventor

1992
Psychoimmunoendocrine aspects of panic disorder.
    Neuropsychobiology, 1992, Volume: 26, Issue:1-2

    Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Agoraphobia; Alprazolam; beta-Endorphin; Corticotrop

1992
A prospective study of panic and anxiety in agoraphobia with panic disorder.
    The British journal of psychiatry : the journal of mental science, 1992, Volume: 160

    Topics: Adult; Agoraphobia; Alprazolam; Anxiety Disorders; Arousal; Combined Modality Therapy; Desensitizati

1992
MDMA ("ecstasy") and panic disorder: induction by a single dose.
    Biological psychiatry, 1992, Nov-15, Volume: 32, Issue:10

    Topics: 3,4-Methylenedioxyamphetamine; Administration, Oral; Adult; Alprazolam; Anxiety Disorders; Arousal;

1992
Cultural and integrative therapy issues in the treatment of a Jamaican woman with panic disorder.
    Family process, 1992, Volume: 31, Issue:2

    Topics: Adult; Alprazolam; Culture; Ethnicity; Female; Humans; Jamaica; Panic Disorder; Psychotherapy; Unite

1992
Characteristics of long-term alprazolam users in the community.
    Journal of clinical psychopharmacology, 1992, Volume: 12, Issue:5

    Topics: Alprazolam; Attitude to Health; Depressive Disorder; Drug Administration Schedule; Humans; Panic Dis

1992
A meta-analysis of treatments for panic disorder with agoraphobia: imipramine, alprazolam, and in vivo exposure.
    Journal of behavior therapy and experimental psychiatry, 1992, Volume: 23, Issue:3

    Topics: Agoraphobia; Alprazolam; Female; Humans; Imipramine; Male; Panic Disorder; Psychiatric Status Rating

1992
Suicide and violence associated with panic attacks.
    Biological psychiatry, 1992, Mar-15, Volume: 31, Issue:6

    Topics: Adult; Alprazolam; Depressive Disorder; Drug Therapy, Combination; Female; Fluoxetine; Humans; Male;

1992
Xanax can lead to dependency.
    American pharmacy, 1992, Volume: NS32, Issue:6

    Topics: Alprazolam; Humans; Panic Disorder; Substance-Related Disorders

1992
Adverse reaction to generic alprazolam.
    The American journal of psychiatry, 1991, Volume: 148, Issue:11

    Topics: Alprazolam; Drugs, Generic; Female; Humans; Middle Aged; Panic Disorder; Recurrence

1991
Follow-up study of patients with panic disorder.
    Archives of general psychiatry, 1991, Volume: 48, Issue:9

    Topics: Alprazolam; Antidepressive Agents, Tricyclic; Behavior Therapy; Combined Modality Therapy; Follow-Up

1991
Surreptitious drug use by panic disorder patients.
    The Journal of clinical psychiatry, 1991, Volume: 52, Issue:10

    Topics: Alprazolam; Clinical Trials as Topic; Humans; Imipramine; Panic Disorder; Placebos; Self Medication

1991
Panic attack precipitated by fluoxetine.
    The Journal of neuropsychiatry and clinical neurosciences, 1989,Spring, Volume: 1, Issue:2

    Topics: Adult; Alprazolam; Fluoxetine; Humans; Male; Obsessive-Compulsive Disorder; Panic Disorder; Psychiat

1989