alprazolam has been researched along with Pain in 18 studies
Alprazolam: A triazolobenzodiazepine compound with antianxiety and sedative-hypnotic actions, that is efficacious in the treatment of PANIC DISORDERS, with or without AGORAPHOBIA, and in generalized ANXIETY DISORDERS. (From AMA Drug Evaluations Annual, 1994, p238)
alprazolam : A member of the class of triazolobenzodiazepines that is 4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine carrying methyl, phenyl and chloro substituents at positions 1, 6 and 8 respectively. Alprazolam is only found in individuals that have taken this drug.
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate five different preoperative anxiolytic regimens in cataract surgery performed under regional anesthesia; to quantify the pain associated with combined peri- and retrobulbar injection (PRBI) of local anesthetic drugs; and to describe a technique of painless eye block." | 9.08 | Evaluation of anxiolysis and pain associated with combined peri- and retrobulbar eye block for cataract surgery. ( Berry, RA; Boezaart, AP; Laubscher, JJ; Nell, ML, 1998) |
| "One hundred chronic pain patients were begun on alprazolam, 1." | 9.06 | Effectiveness of alprazolam in the treatment of chronic pain: results of a preliminary study. ( Cicala, RS; Westbrook, L; Wright, H, 1990) |
| "To evaluate the effect of pre-operative alprazolam medication on anxiety and pain in flexible cystoscopy for bladder cancer follow-up." | 7.85 | Does using alprazolam during outpatient flexible cystoscopy decrease anxiety and pain? ( Cevik, I; Dillioglugil, O; Karakose, A; Koprulu, S; Ozkan, TA, 2017) |
| " While undergoing treatment with the minor tranquilizer alprazolam for a coincidental psychiatric disturbance, 39 patients with malignancies and an associated causalgic pain syndrome had a marked analgesic response." | 7.67 | Analgesic effect of alprazolam in patients with chronic, organic pain of malignant origin. ( Adams, F; Fernandez, F; Holmes, VF, 1987) |
| "Alprazolam resulted in lower anxiety and pain ratings during pain stimulation, supporting the idea that (presumably pain-related) anxiety may increase the experience of pain." | 6.69 | No interactive effects of naltrexone and benzodiazepines on pain during phobic fear. ( Arntz, A; Janssen, SA, 1999) |
| "Flurbiprofen was found to have a significant analgesic effect but this was not enhanced by combining it with alprazolam." | 6.67 | Comparison of flurbiprofen and alprazolam in the management of chronic pain syndrome. ( Wilson, A, 1990) |
| "Alprazolam is a triazolobenzodiazepine derivative used as a tranquilizer." | 5.37 | Effects of Alprazolam, Zolpidem and Zopiclone, and of chronic inflammation on peripheral experimental algesia in Wistar rats. ( Antonescu, A; Bogdan, M; Dobjanschi, L; Moş, I; Mureşan, M; Muţiu, G; Zdrîncă, M, 2011) |
| " As part of an ongoing research program, we examined the effects of a commonly prescribed combination of medications for pain relief: alprazolam, a benzodiazepine, and a hydrocodone preparation, a combination opiate and acetaminophen, on a simulated driving protocol." | 5.27 | Evaluating drugged driving: Effects of exemplar pain and anxiety medications. ( Brown, TL; Gaffney, G; Milavetz, G; Spurgin, A, 2018) |
| "Patients experienced greater reduction in anxiety score after medication with sublingual alprazolam (mean 2." | 5.19 | Premedication with sublingual or oral alprazolam in adults undergoing diagnostic upper gastrointestinal endoscopy. ( Gholamrezaei, A; Khodadoostan, M; Minakari, M; Shavakhi, A; Shavakhi, S; Soleiman, S; Tahery, A, 2014) |
| "To evaluate five different preoperative anxiolytic regimens in cataract surgery performed under regional anesthesia; to quantify the pain associated with combined peri- and retrobulbar injection (PRBI) of local anesthetic drugs; and to describe a technique of painless eye block." | 5.08 | Evaluation of anxiolysis and pain associated with combined peri- and retrobulbar eye block for cataract surgery. ( Berry, RA; Boezaart, AP; Laubscher, JJ; Nell, ML, 1998) |
| "One hundred chronic pain patients were begun on alprazolam, 1." | 5.06 | Effectiveness of alprazolam in the treatment of chronic pain: results of a preliminary study. ( Cicala, RS; Westbrook, L; Wright, H, 1990) |
| "To evaluate the effect of pre-operative alprazolam medication on anxiety and pain in flexible cystoscopy for bladder cancer follow-up." | 3.85 | Does using alprazolam during outpatient flexible cystoscopy decrease anxiety and pain? ( Cevik, I; Dillioglugil, O; Karakose, A; Koprulu, S; Ozkan, TA, 2017) |
| " While undergoing treatment with the minor tranquilizer alprazolam for a coincidental psychiatric disturbance, 39 patients with malignancies and an associated causalgic pain syndrome had a marked analgesic response." | 3.67 | Analgesic effect of alprazolam in patients with chronic, organic pain of malignant origin. ( Adams, F; Fernandez, F; Holmes, VF, 1987) |
| "Alprazolam resulted in lower anxiety and pain ratings during pain stimulation, supporting the idea that (presumably pain-related) anxiety may increase the experience of pain." | 2.69 | No interactive effects of naltrexone and benzodiazepines on pain during phobic fear. ( Arntz, A; Janssen, SA, 1999) |
| "Flurbiprofen was found to have a significant analgesic effect but this was not enhanced by combining it with alprazolam." | 2.67 | Comparison of flurbiprofen and alprazolam in the management of chronic pain syndrome. ( Wilson, A, 1990) |
| "Alprazolam is a triazolobenzodiazepine derivative used as a tranquilizer." | 1.37 | Effects of Alprazolam, Zolpidem and Zopiclone, and of chronic inflammation on peripheral experimental algesia in Wistar rats. ( Antonescu, A; Bogdan, M; Dobjanschi, L; Moş, I; Mureşan, M; Muţiu, G; Zdrîncă, M, 2011) |
| "Alprazolam is a triazolobenzodiazepine, with a potent anxiolytic action and a short half-life." | 1.30 | Antinociceptive interaction between alprazolam and opioids. ( Pick, CG, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (11.11) | 18.7374 |
| 1990's | 8 (44.44) | 18.2507 |
| 2000's | 3 (16.67) | 29.6817 |
| 2010's | 5 (27.78) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ozkan, TA | 1 |
| Koprulu, S | 1 |
| Karakose, A | 1 |
| Dillioglugil, O | 1 |
| Cevik, I | 1 |
| Brown, TL | 1 |
| Milavetz, G | 1 |
| Gaffney, G | 1 |
| Spurgin, A | 1 |
| Shavakhi, A | 1 |
| Soleiman, S | 1 |
| Gholamrezaei, A | 1 |
| Khodadoostan, M | 1 |
| Shavakhi, S | 1 |
| Tahery, A | 1 |
| Minakari, M | 1 |
| Camus, M | 1 |
| Heyries, L | 1 |
| Metivier-Cesbron, E | 1 |
| Le Balleur, Y | 1 |
| Koch, S | 1 |
| Lesur, G | 1 |
| Zdrîncă, M | 2 |
| Muţiu, G | 1 |
| Bogdan, M | 1 |
| Dobjanschi, L | 1 |
| Antonescu, A | 2 |
| Moş, I | 1 |
| Mureşan, M | 1 |
| Dolezal, T | 1 |
| Krsiak, M | 1 |
| Loscalzo, LM | 1 |
| Wasowski, C | 1 |
| Paladini, AC | 1 |
| Marder, M | 1 |
| Silberman, EK | 1 |
| Sullivan, JL | 1 |
| Katz, RC | 1 |
| Wilson, L | 1 |
| Frazer, N | 1 |
| Pick, CG | 1 |
| Boezaart, AP | 1 |
| Berry, RA | 1 |
| Laubscher, JJ | 1 |
| Nell, ML | 1 |
| Hans, P | 1 |
| Coussaert, E | 1 |
| Cantraine, F | 1 |
| Dewandre, PY | 1 |
| Brichant, JF | 1 |
| Grevesse, M | 1 |
| Lamy, M | 1 |
| Janssen, SA | 1 |
| Arntz, A | 1 |
| Jenck, F | 1 |
| Wichmann, J | 1 |
| Dautzenberg, FM | 1 |
| Moreau, JL | 1 |
| Ouagazzal, AM | 1 |
| Martin, JR | 1 |
| Lundstrom, K | 1 |
| Cesura, AM | 1 |
| Poli, SM | 1 |
| Roever, S | 1 |
| Kolczewski, S | 1 |
| Adam, G | 1 |
| Kilpatrick, G | 1 |
| Westbrook, L | 1 |
| Cicala, RS | 1 |
| Wright, H | 1 |
| Russell, IJ | 1 |
| Fletcher, EM | 1 |
| Michalek, JE | 1 |
| McBroom, PC | 1 |
| Hester, GG | 1 |
| Wilson, A | 1 |
| Fernandez, F | 1 |
| Adams, F | 1 |
| Holmes, VF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison Between Sublingual and Oral Alprazolam as Conscious Sedation for Upper Gastrointestinal Endoscopy[NCT01949038] | Phase 2/Phase 3 | 220 participants (Actual) | Interventional | 2011-09-30 | Completed | ||
| Comparing Efficacy of Oral Midazolam and Sublingual Alprazolam in Reducing Anxiety and Pain/Discomfort Related to Diagnostic Upper Gastrointestinal Endoscopy in Adults[NCT03130842] | Phase 2/Phase 3 | 136 participants (Actual) | Interventional | 2016-09-17 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for alprazolam and Pain
| Article | Year |
|---|---|
Atypical depression.
Topics: Alprazolam; Anxiety Disorders; Benzodiazepines; Bipolar Disorder; Character; Chronic Disease; Clinic | 1984 |
8 trials available for alprazolam and Pain
| Article | Year |
|---|---|
Evaluating drugged driving: Effects of exemplar pain and anxiety medications.
Topics: Acetaminophen; Adult; Alprazolam; Anxiety; Cross-Over Studies; Double-Blind Method; Driving Under th | 2018 |
Premedication with sublingual or oral alprazolam in adults undergoing diagnostic upper gastrointestinal endoscopy.
Topics: Administration, Intravenous; Administration, Oral; Administration, Sublingual; Adult; Alprazolam; An | 2014 |
Premedication with sublingual or oral alprazolam in adults undergoing diagnostic upper gastrointestinal endoscopy.
Topics: Administration, Intravenous; Administration, Oral; Administration, Sublingual; Adult; Alprazolam; An | 2014 |
Premedication with sublingual or oral alprazolam in adults undergoing diagnostic upper gastrointestinal endoscopy.
Topics: Administration, Intravenous; Administration, Oral; Administration, Sublingual; Adult; Alprazolam; An | 2014 |
Premedication with sublingual or oral alprazolam in adults undergoing diagnostic upper gastrointestinal endoscopy.
Topics: Administration, Intravenous; Administration, Oral; Administration, Sublingual; Adult; Alprazolam; An | 2014 |
Atypical depression.
Topics: Alprazolam; Anxiety Disorders; Benzodiazepines; Bipolar Disorder; Character; Chronic Disease; Clinic | 1984 |
Evaluation of anxiolysis and pain associated with combined peri- and retrobulbar eye block for cataract surgery.
Topics: Aged; Alprazolam; Anesthesia, Local; Anesthetics, Local; Anti-Anxiety Agents; Anxiety; Bromazepam; B | 1998 |
No interactive effects of naltrexone and benzodiazepines on pain during phobic fear.
Topics: Adolescent; Adult; Alprazolam; Anxiety; Benzodiazepines; Drug Interactions; Electroshock; Female; Hu | 1999 |
Effectiveness of alprazolam in the treatment of chronic pain: results of a preliminary study.
Topics: Alprazolam; Anti-Anxiety Agents; Chronic Disease; Female; Humans; Male; Pain; Pain Measurement | 1990 |
Treatment of primary fibrositis/fibromyalgia syndrome with ibuprofen and alprazolam. A double-blind, placebo-controlled study.
Topics: Adolescent; Adult; Aged; Alprazolam; Depression; Double-Blind Method; Fibromyalgia; Humans; Ibuprofe | 1991 |
Comparison of flurbiprofen and alprazolam in the management of chronic pain syndrome.
Topics: Adult; Aged; Alprazolam; Chronic Disease; Double-Blind Method; Female; Flurbiprofen; Humans; Male; M | 1990 |
10 other studies available for alprazolam and Pain
| Article | Year |
|---|---|
Does using alprazolam during outpatient flexible cystoscopy decrease anxiety and pain?
Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Ambulatory Care; Anti-Anxiety Agents; Anxiety; Cystoscop | 2017 |
[Commentary on the work of Shavakhi A et al., pp. 633].
Topics: Alprazolam; Anxiety; Endoscopy, Gastrointestinal; Female; Humans; Hypnotics and Sedatives; Male; Pai | 2014 |
Effects of Alprazolam, Zolpidem and Zopiclone, and of chronic inflammation on peripheral experimental algesia in Wistar rats.
Topics: Alprazolam; Animals; Azabicyclo Compounds; Chronic Disease; Granuloma, Foreign-Body; Inflammation; M | 2011 |
Augmentation of analgesic effect of ibuprofen by alprazolam in experimental model of pain.
Topics: Acetic Acid; Acute Disease; Administration, Oral; Alprazolam; Analgesics, Non-Narcotic; Animals; Dis | 2002 |
Opioid receptors are involved in the sedative and antinociceptive effects of hesperidin as well as in its potentiation with benzodiazepines.
Topics: Acetic Acid; Alprazolam; Analgesics; Animals; Behavior, Animal; Benzodiazepines; Dose-Response Relat | 2008 |
Anxiety and its determinants in patients undergoing magnetic resonance imaging.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alprazolam; Anxiety; Fear; Female; Humans; Magnetic Reso | 1994 |
Antinociceptive interaction between alprazolam and opioids.
Topics: Alprazolam; Animals; Dose-Response Relationship, Drug; Drug Interactions; Male; Mice; Mice, Inbred S | 1997 |
Effects of target-controlled anesthesia with propofol and sufentanil on the hemodynamic response to Mayfield head holder application.
Topics: Adjuvants, Anesthesia; Alprazolam; Analysis of Variance; Anesthesia, Intravenous; Anesthetics, Intra | 1998 |
A synthetic agonist at the orphanin FQ/nociceptin receptor ORL1: anxiolytic profile in the rat.
Topics: Acoustic Stimulation; Alprazolam; Animals; Anti-Anxiety Agents; Cognition; Conflict, Psychological; | 2000 |
Analgesic effect of alprazolam in patients with chronic, organic pain of malignant origin.
Topics: Adjustment Disorders; Adolescent; Adult; Aged; Alprazolam; Causalgia; Chronic Disease; Depressive Di | 1987 |