Page last updated: 2024-10-22

alprazolam and Neonatal Abstinence Syndrome

alprazolam has been researched along with Neonatal Abstinence Syndrome in 2 studies

Alprazolam: A triazolobenzodiazepine compound with antianxiety and sedative-hypnotic actions, that is efficacious in the treatment of PANIC DISORDERS, with or without AGORAPHOBIA, and in generalized ANXIETY DISORDERS. (From AMA Drug Evaluations Annual, 1994, p238)
alprazolam : A member of the class of triazolobenzodiazepines that is 4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine carrying methyl, phenyl and chloro substituents at positions 1, 6 and 8 respectively. Alprazolam is only found in individuals that have taken this drug.

Neonatal Abstinence Syndrome: Fetal and neonatal addiction and withdrawal as a result of the mother's dependence on drugs during pregnancy. Withdrawal or abstinence symptoms develop shortly after birth. Symptoms exhibited are loud, high-pitched crying, sweating, yawning and gastrointestinal disturbances.

Research Excerpts

ExcerptRelevanceReference
"The newborn of a mother reporting alprazolam use during pregnancy presented with respiratory distress and clinical features consistent with neonatal withdrawal syndrome or neonatal sepsis of vertical transmission."7.74Confirmation of gestational exposure to alprazolam by analysis of biological matrices in a newborn with neonatal sepsis. ( García-Algar, O; López-Vílchez, MA; Martín, I; Mur, A; Pacifici, R; Pellegrini, M; Pichini, S; Rossi, S, 2007)
" In this study, the association between NAS and plasma alprazolam concentration was examined using the measured neonatal concentrations in the time series as well as simulated plasma concentrations of pregnant woman and neonate by physiologically based pharmacokinetic (PBPK) modeling."5.51Pharmacokinetic assessment of alprazolam-induced neonatal abstinence syndrome using physiologically based pharmacokinetic model. ( Fujioka, K; Fukushima, S; Hashimoto, M; Iijima, K; Mishima, Y; Yamakawa, K; Yamamoto, K; Yano, I, 2019)
"The newborn of a mother reporting alprazolam use during pregnancy presented with respiratory distress and clinical features consistent with neonatal withdrawal syndrome or neonatal sepsis of vertical transmission."3.74Confirmation of gestational exposure to alprazolam by analysis of biological matrices in a newborn with neonatal sepsis. ( García-Algar, O; López-Vílchez, MA; Martín, I; Mur, A; Pacifici, R; Pellegrini, M; Pichini, S; Rossi, S, 2007)
" In this study, the association between NAS and plasma alprazolam concentration was examined using the measured neonatal concentrations in the time series as well as simulated plasma concentrations of pregnant woman and neonate by physiologically based pharmacokinetic (PBPK) modeling."1.51Pharmacokinetic assessment of alprazolam-induced neonatal abstinence syndrome using physiologically based pharmacokinetic model. ( Fujioka, K; Fukushima, S; Hashimoto, M; Iijima, K; Mishima, Y; Yamakawa, K; Yamamoto, K; Yano, I, 2019)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yamamoto, K1
Fukushima, S1
Mishima, Y1
Hashimoto, M1
Yamakawa, K1
Fujioka, K1
Iijima, K1
Yano, I1
García-Algar, O1
López-Vílchez, MA1
Martín, I1
Mur, A1
Pellegrini, M1
Pacifici, R1
Rossi, S1
Pichini, S1

Other Studies

2 other studies available for alprazolam and Neonatal Abstinence Syndrome

ArticleYear
Pharmacokinetic assessment of alprazolam-induced neonatal abstinence syndrome using physiologically based pharmacokinetic model.
    Drug metabolism and pharmacokinetics, 2019, Volume: 34, Issue:6

    Topics: Alprazolam; Female; Humans; Hypnotics and Sedatives; Models, Biological; Neonatal Abstinence Syndrom

2019
Confirmation of gestational exposure to alprazolam by analysis of biological matrices in a newborn with neonatal sepsis.
    Clinical toxicology (Philadelphia, Pa.), 2007, Volume: 45, Issue:3

    Topics: Adult; Alprazolam; Anti-Anxiety Agents; Diagnosis, Differential; Female; Fetal Blood; Hair; Humans;

2007