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alprazolam and Cognition Disorders

alprazolam has been researched along with Cognition Disorders in 7 studies

Alprazolam: A triazolobenzodiazepine compound with antianxiety and sedative-hypnotic actions, that is efficacious in the treatment of PANIC DISORDERS, with or without AGORAPHOBIA, and in generalized ANXIETY DISORDERS. (From AMA Drug Evaluations Annual, 1994, p238)
alprazolam : A member of the class of triazolobenzodiazepines that is 4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine carrying methyl, phenyl and chloro substituents at positions 1, 6 and 8 respectively. Alprazolam is only found in individuals that have taken this drug.

Cognition Disorders: Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment.

Research Excerpts

ExcerptRelevanceReference
"Alprazolam was as effective as low dose haloperidol in this population."2.69Alprazolam as an alternative to low-dose haloperidol in older, cognitively impaired nursing facility patients. ( Benfield, WR; Christensen, DB, 1998)
"Transgenic R6/2 mice carrying the Huntington's disease (HD) mutation show disrupted circadian rhythms that worsen as the disease progresses."1.34Pharmacological imposition of sleep slows cognitive decline and reverses dysregulation of circadian gene expression in a transgenic mouse model of Huntington's disease. ( Chesham, JE; Dyball, R; Hastings, MH; Inyushkin, AN; Maywood, ES; Morton, AJ; Pallier, PN; Zheng, Z, 2007)
"Imidazenil is a highly potent partial allosteric modulator of gamma-aminobutyric acid action at a great variety of gamma-aminobutyric acid(A) receptors, whereas alprazolam is a full allosteric modulator at these receptors."1.29Imidazenil, a new anxiolytic and anticonvulsant drug, attenuates a benzodiazepine-induced cognition deficit in monkeys. ( Auta, J; Costa, E; Guidotti, A; Thompson, DM, 1995)
" The results have implications for evaluating the safety of the long-term use of BZ medications."1.27Chronic use of benzodiazepines and psychomotor and cognitive test performance. ( Geller, AM; Lucki, I; Rickels, K, 1986)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's2 (28.57)18.2507
2000's3 (42.86)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pallier, PN2
Morton, AJ2
Vandesquille, M1
Carrié, I1
Louis, C1
Beracochea, D1
Lestage, P1
Snyder, PJ1
Werth, J1
Giordani, B1
Caveney, AF1
Feltner, D1
Maruff, P1
Maywood, ES1
Zheng, Z1
Chesham, JE1
Inyushkin, AN1
Dyball, R1
Hastings, MH1
Thompson, DM1
Auta, J1
Guidotti, A1
Costa, E1
Christensen, DB1
Benfield, WR1
Lucki, I1
Rickels, K1
Geller, AM1

Trials

2 trials available for alprazolam and Cognition Disorders

ArticleYear
A method for determining the magnitude of change across different cognitive functions in clinical trials: the effects of acute administration of two different doses alprazolam.
    Human psychopharmacology, 2005, Volume: 20, Issue:4

    Topics: Adult; Alprazolam; Anti-Anxiety Agents; Association Learning; Attention; Cognition Disorders; Double

2005
Alprazolam as an alternative to low-dose haloperidol in older, cognitively impaired nursing facility patients.
    Journal of the American Geriatrics Society, 1998, Volume: 46, Issue:5

    Topics: Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Antipsychotic Agents; Behavioral Symptoms;

1998

Other Studies

5 other studies available for alprazolam and Cognition Disorders

ArticleYear
Management of sleep/wake cycles improves cognitive function in a transgenic mouse model of Huntington's disease.
    Brain research, 2009, Jul-07, Volume: 1279

    Topics: Affect; Alprazolam; Animals; Benzhydryl Compounds; Body Weight; Central Nervous System Stimulants; C

2009
Effects of positive modulators of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors in a benzodiazepine-induced deficit of spatial discrimination in mice.
    Journal of psychopharmacology (Oxford, England), 2012, Volume: 26, Issue:6

    Topics: Alprazolam; Amnesia; Animals; Behavior, Animal; Benzothiadiazines; Cognition Disorders; Discriminati

2012
Pharmacological imposition of sleep slows cognitive decline and reverses dysregulation of circadian gene expression in a transgenic mouse model of Huntington's disease.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Jul-18, Volume: 27, Issue:29

    Topics: Age Factors; Alprazolam; Animals; Cell Cycle Proteins; Chloral Hydrate; Choice Behavior; Circadian R

2007
Imidazenil, a new anxiolytic and anticonvulsant drug, attenuates a benzodiazepine-induced cognition deficit in monkeys.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 273, Issue:3

    Topics: Alprazolam; Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Cognition Disorders; Ery

1995
Chronic use of benzodiazepines and psychomotor and cognitive test performance.
    Psychopharmacology, 1986, Volume: 88, Issue:4

    Topics: Adult; Affect; Aged; Alprazolam; Anti-Anxiety Agents; Benzodiazepines; Clorazepate Dipotassium; Cogn

1986