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alprazolam and Chronic Insomnia

alprazolam has been researched along with Chronic Insomnia in 19 studies

Alprazolam: A triazolobenzodiazepine compound with antianxiety and sedative-hypnotic actions, that is efficacious in the treatment of PANIC DISORDERS, with or without AGORAPHOBIA, and in generalized ANXIETY DISORDERS. (From AMA Drug Evaluations Annual, 1994, p238)
alprazolam : A member of the class of triazolobenzodiazepines that is 4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine carrying methyl, phenyl and chloro substituents at positions 1, 6 and 8 respectively. Alprazolam is only found in individuals that have taken this drug.

Research Excerpts

ExcerptRelevanceReference
"Restless leg syndrome is a frequently misdiagnosed and often misunderstood condition contributing to a complaint of insomnia in geriatric patients."5.27Possible efficacy of alprazolam in restless leg syndrome. ( Brown, L; Hirschowitz, J; Scharf, MB, 1986)
"Olanzapine antagonizes multiple receptors and has potential to treat a host of symptoms including nausea, anorexia, anxiety, and insomnia, but healthcare providers should be mindful of potential risks and unclear benefits for off-label indications."4.31Benefits and risks of off-label olanzapine use for symptom management in cancer patients-a case report. ( Amaram-Davila, JS; Bruera, E; Dev, R; Fortuno, ES; Haider, A, 2023)
"The alprazolam group had lower higher scores in PSQI than that before treatment, with great statistical significant in difference (P < 0."2.78[Study on efficacy of zaoren anshen capsules in treating senile insomnia and changes in its hemorheology]. ( Gan, JG; Qin, GX; Tian, GQ, 2013)
"Seventy-six insomnia patients were randomly allocated to an acupuncture group and a medication group, 38 cases in each group."2.73[Observation on the therapeutic effect of neck clustered needling on insomnia]. ( Ma, XP; Qi, LZ; Yang, L, 2008)
"Long-term, nightly benzodiazepine treatment of injurious parasomnias and other disorders of disrupted nocturnal sleep resulted in sustained efficacy in most cases, with low risk of dosage tolerance, adverse effects, or abuse."2.68Long-term, nightly benzodiazepine treatment of injurious parasomnias and other disorders of disrupted nocturnal sleep in 170 adults. ( Mahowald, MW; Schenck, CH, 1996)
"Restless leg syndrome is a frequently misdiagnosed and often misunderstood condition contributing to a complaint of insomnia in geriatric patients."1.27Possible efficacy of alprazolam in restless leg syndrome. ( Brown, L; Hirschowitz, J; Scharf, MB, 1986)
"Alprazolam treatment was tapered in 17 panic patients at a rate of 10% of the starting dose every 3 days."1.27Discontinuation of alprazolam treatment in panic patients. ( Campeas, R; Davies, SO; Fyer, AJ; Goetz, D; Gorman, JM; Klein, DF; Levin, A; Liebowitz, MR, 1987)
"Alprazolam is a new type triazolobenzodiazepine anxiolytic agent."1.26Alprazolam, a new type anxiolytic in neurotic patients. A pilot study. ( Itoh, H; Miura, S; Takahashi, R, 1980)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19908 (42.11)18.7374
1990's2 (10.53)18.2507
2000's3 (15.79)29.6817
2010's3 (15.79)24.3611
2020's3 (15.79)2.80

Authors

AuthorsStudies
Lu, X1
Huang, H1
Huang, Y1
Zhang, L1
Wu, X1
Wang, Z1
Xiao, J1
Dev, R1
Fortuno, ES1
Amaram-Davila, JS1
Haider, A1
Bruera, E1
Kalita, J1
Dongre, N1
Misra, UK1
Gan, JG1
Tian, GQ1
Qin, GX1
Li, Y1
Li, Z1
Lei, F1
Du, L1
Tang, X1
Cui, JF1
Yang, W1
Xie, YM1
Sun, Y1
Zhuang, Y1
Wang, YY1
Qi, LZ1
Ma, XP1
Yang, L1
Porecha, S1
shah, T1
Jogani, V1
Naik, S1
Misra, A1
Kumar, A1
Kulkarni, SK1
Itoh, H1
Takahashi, R1
Miura, S1
Ayd, FJ1
Schenck, CH1
Mahowald, MW1
Freeman, S1
Rapport, DJ1
Covington, EC1
Allen, RM1
Slak, S1
Scharf, MB1
Brown, L1
Hirschowitz, J1
Fyer, AJ1
Liebowitz, MR1
Gorman, JM1
Campeas, R1
Levin, A1
Davies, SO1
Goetz, D1
Klein, DF1

Trials

3 trials available for alprazolam and Chronic Insomnia

ArticleYear
[Study on efficacy of zaoren anshen capsules in treating senile insomnia and changes in its hemorheology].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2013, Volume: 38, Issue:2

    Topics: Aged; Aged, 80 and over; Alprazolam; Blood Viscosity; Capsules; Drugs, Chinese Herbal; Female; Hemor

2013
[Observation on the therapeutic effect of neck clustered needling on insomnia].
    Zhongguo zhen jiu = Chinese acupuncture & moxibustion, 2008, Volume: 28, Issue:12

    Topics: Acupuncture Points; Acupuncture Therapy; Adult; Aged; Alprazolam; Female; Humans; Hypnotics and Seda

2008
Long-term, nightly benzodiazepine treatment of injurious parasomnias and other disorders of disrupted nocturnal sleep in 170 adults.
    The American journal of medicine, 1996, Volume: 100, Issue:3

    Topics: Adult; Alprazolam; Anti-Anxiety Agents; Chronic Disease; Clonazepam; Drug Administration Schedule; F

1996

Other Studies

16 other studies available for alprazolam and Chronic Insomnia

ArticleYear
Evaluation of anticholinergic burden in elderly outpatients and the risk factors.
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2023, Jan-28, Volume: 48, Issue:1

    Topics: Aged; Alprazolam; Cholinergic Antagonists; Eszopiclone; Humans; Metoprolol; Nifedipine; Outpatients;

2023
Benefits and risks of off-label olanzapine use for symptom management in cancer patients-a case report.
    Annals of palliative medicine, 2023, Volume: 12, Issue:3

    Topics: Adenocarcinoma; Aged; Alprazolam; Anorexia; Antiemetics; Cisplatin; Female; Humans; Male; Middle Age

2023
Myasthenic crisis due to anxiety and insomnia during COVID -19 pandemic.
    Sleep medicine, 2020, Volume: 75

    Topics: Alprazolam; Anti-Anxiety Agents; Anxiety; COVID-19; Disease Progression; Humans; Male; Middle Aged;

2020
Persistent insomnia despite long-term nightly use of sleeping pills.
    Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2013, Aug-15, Volume: 9, Issue:8

    Topics: Alprazolam; Continuous Positive Airway Pressure; Female; Follow-Up Studies; Humans; Hypnotics and Se

2013
[Real-world analysis of concurrent diseases and medicine use among patients with insomnia].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2014, Volume: 39, Issue:18

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Antipsychotic Agents; B

2014
Microemulsion based intranasal delivery system for treatment of insomnia.
    Drug delivery, 2009, Volume: 16, Issue:3

    Topics: Administration, Intranasal; Alprazolam; Animals; Diazepam; Disease Models, Animal; Drug Compounding;

2009
On the sleep promoting effects of BR-16A: interaction with GABAergic modulators.
    Indian journal of experimental biology, 2004, Volume: 42, Issue:5

    Topics: Alprazolam; Animals; Dose-Response Relationship, Drug; Drug Interactions; Female; GABA Agonists; GAB

2004
Alprazolam, a new type anxiolytic in neurotic patients. A pilot study.
    International pharmacopsychiatry, 1980, Volume: 15, Issue:6

    Topics: Adult; Age Factors; Alprazolam; Anti-Anxiety Agents; Benzodiazepines; Humans; Neurotic Disorders; Pi

1980
Three more benzodiazepines.
    Drug and therapeutics bulletin, 1983, Aug-12, Volume: 21, Issue:16

    Topics: Alprazolam; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Bromazepam; Flunitrazepam; Humans; Sleep

1983
Is it anxiety or depression?
    Southern medical journal, 1984, Volume: 77, Issue:10

    Topics: Aged; Alprazolam; Antidepressive Agents; Anxiety; Benzodiazepines; Circadian Rhythm; Depression; Dia

1984
The realities of clonazepam discontinuation.
    Psychiatric services (Washington, D.C.), 1997, Volume: 48, Issue:7

    Topics: Alprazolam; Anxiety Disorders; Benzodiazepines; Clonazepam; Drug Administration Schedule; GABA Modul

1997
Motor phenomena in benzodiazepine withdrawal.
    Hospital & community psychiatry, 1989, Volume: 40, Issue:12

    Topics: Aged; Alprazolam; Anti-Anxiety Agents; Diagnosis, Differential; Diazepam; Drug Therapy, Combination;

1989
Tranquilizers and sedative/hypnotics: appropriate use in the elderly.
    Geriatrics, 1986, Volume: 41, Issue:5

    Topics: Aged; Alprazolam; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Half-Life; Humans; Hypnotics and Se

1986
Alprazolam withdrawal insomnia.
    Psychological reports, 1986, Volume: 58, Issue:2

    Topics: Alprazolam; Anti-Anxiety Agents; Benzodiazepines; Humans; Sleep Initiation and Maintenance Disorders

1986
Possible efficacy of alprazolam in restless leg syndrome.
    The Hillside journal of clinical psychiatry, 1986, Volume: 8, Issue:2

    Topics: Aged; Aged, 80 and over; Alprazolam; Dose-Response Relationship, Drug; Drug Tolerance; Female; Human

1986
Discontinuation of alprazolam treatment in panic patients.
    The American journal of psychiatry, 1987, Volume: 144, Issue:3

    Topics: Acute Disease; Adult; Alprazolam; Anxiety Disorders; Dizziness; Fear; Female; Humans; Male; Middle A

1987
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