Page last updated: 2024-10-22

alprazolam and Amnesia

alprazolam has been researched along with Amnesia in 11 studies

Alprazolam: A triazolobenzodiazepine compound with antianxiety and sedative-hypnotic actions, that is efficacious in the treatment of PANIC DISORDERS, with or without AGORAPHOBIA, and in generalized ANXIETY DISORDERS. (From AMA Drug Evaluations Annual, 1994, p238)
alprazolam : A member of the class of triazolobenzodiazepines that is 4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine carrying methyl, phenyl and chloro substituents at positions 1, 6 and 8 respectively. Alprazolam is only found in individuals that have taken this drug.

Amnesia: Pathologic partial or complete loss of the ability to recall past experiences (AMNESIA, RETROGRADE) or to form new memories (AMNESIA, ANTEROGRADE). This condition may be of organic or psychologic origin. Organic forms of amnesia are usually associated with dysfunction of the DIENCEPHALON or HIPPOCAMPUS. (From Adams et al., Principles of Neurology, 6th ed, pp426-7)

Research Excerpts

ExcerptRelevanceReference
" The brain acetylcholinesterase activity (AChE), serum cholesterol, brain monoaldehyde (MDA), brain reduced glutathione (GSH) and brain nitrite were estimated and Alprazolam, Scopolamine and Electroshock induced amnesia was employed to describe the actions."7.85Trachyspermum ammi Seeds Supplementation Helps Reverse Scopolamine, Alprazolam and Electroshock Induced Amnesia. ( Parle, M; Soni, K, 2017)
"Alprazolam produced anterograde as well as retrograde amnesia in mice assessed using elevated plus-maze."7.70Possible mechanism of alprazolam-induced amnesia in mice. ( Sharma, A; Singh, M; Singh, N, 1998)
" The brain acetylcholinesterase activity (AChE), serum cholesterol, brain monoaldehyde (MDA), brain reduced glutathione (GSH) and brain nitrite were estimated and Alprazolam, Scopolamine and Electroshock induced amnesia was employed to describe the actions."3.85Trachyspermum ammi Seeds Supplementation Helps Reverse Scopolamine, Alprazolam and Electroshock Induced Amnesia. ( Parle, M; Soni, K, 2017)
" Alprazolam, Scopolamine and high fat diet (HFD) induced amnesia served as interoceptive memory models where as, Water-maze and Elevated plus-maze served as exteroceptive models."3.74Reversal of memory deficits by Atorvastatin and Simvastatin in rats. ( Parle, M; Singh, N, 2007)
"Alprazolam produced anterograde as well as retrograde amnesia in mice assessed using elevated plus-maze."3.70Possible mechanism of alprazolam-induced amnesia in mice. ( Sharma, A; Singh, M; Singh, N, 1998)
" Amnesia was associated with the drug combination, and a protective action of the long-lived drugs against lidocaine toxicity is theorized."3.70Oral sedation allows for comfort and amnesia during office surgery. ( Gatti, JE, 2000)
" Results suggest that individuals who take benzodiazepines will perform less well on an anterograde memory delayed recall task completed after dosing on the sixth day of treatment, but no similar difference will be found in performance on a similar task completed just before dosing on the sixth day."2.66Anxiolytics and memory: a comparison of lorazepam and alprazolam. ( Gabrielli, WF; Goodwin, DW; Kumar, R; Mac, DS, 1987)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19902 (18.18)18.7374
1990's2 (18.18)18.2507
2000's3 (27.27)29.6817
2010's3 (27.27)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Gao, X1
Chen, M1
Huang, Y1
Yang, X1
Chen, X1
Yuan, G1
Soni, K1
Parle, M3
García-Gutiérrez, MS1
Manzanares, J1
Vandesquille, M1
Carrié, I1
Louis, C1
Beracochea, D1
Lestage, P1
Singh, N3
Barbee, JG1
Sharma, A1
Singh, M1
Gatti, JE1
Terrell, HB1
Kumar, R1
Mac, DS1
Gabrielli, WF1
Goodwin, DW1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Neurocognitive Functioning Following The PROMETA® Treatment Protocol In Subjects With Alcohol Dependence[NCT00570388]120 participants (Anticipated)Interventional2007-03-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for alprazolam and Amnesia

ArticleYear
Memory, benzodiazepines, and anxiety: integration of theoretical and clinical perspectives.
    The Journal of clinical psychiatry, 1993, Volume: 54 Suppl

    Topics: Alprazolam; Amnesia; Anxiety Disorders; Benzodiazepines; Dose-Response Relationship, Drug; Humans; M

1993

Trials

1 trial available for alprazolam and Amnesia

ArticleYear
Anxiolytics and memory: a comparison of lorazepam and alprazolam.
    The Journal of clinical psychiatry, 1987, Volume: 48, Issue:4

    Topics: Adult; Alprazolam; Amnesia; Double-Blind Method; Humans; Lorazepam; Male; Memory; Memory, Short-Term

1987

Other Studies

9 other studies available for alprazolam and Amnesia

ArticleYear
Alprazolam and clarithromycin interaction induced lethargy and short-term memory loss in an elderly patient: a case report.
    Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society, 2021, Volume: 21, Issue:1

    Topics: Aged; Alprazolam; Amnesia; Clarithromycin; Double-Blind Method; Humans; Lethargy; Memory, Short-Term

2021
Trachyspermum ammi Seeds Supplementation Helps Reverse Scopolamine, Alprazolam and Electroshock Induced Amnesia.
    Neurochemical research, 2017, Volume: 42, Issue:5

    Topics: Acetylcholinesterase; Alprazolam; Amnesia; Animals; Apiaceae; Dietary Supplements; Dose-Response Rel

2017
The cannabinoid CB1 receptor is involved in the anxiolytic, sedative and amnesic actions of benzodiazepines.
    Journal of psychopharmacology (Oxford, England), 2010, Volume: 24, Issue:5

    Topics: Alprazolam; Amnesia; Amygdala; Animals; Anti-Anxiety Agents; Anxiety; Avoidance Learning; Behavior,

2010
Effects of positive modulators of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors in a benzodiazepine-induced deficit of spatial discrimination in mice.
    Journal of psychopharmacology (Oxford, England), 2012, Volume: 26, Issue:6

    Topics: Alprazolam; Amnesia; Animals; Behavior, Animal; Benzothiadiazines; Cognition Disorders; Discriminati

2012
Sildenafil improves acquisition and retention of memory in mice.
    Indian journal of physiology and pharmacology, 2003, Volume: 47, Issue:3

    Topics: Alprazolam; Amnesia; Animals; Caffeine; Cholinesterase Inhibitors; Dose-Response Relationship, Drug;

2003
Reversal of memory deficits by Atorvastatin and Simvastatin in rats.
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2007, Volume: 127, Issue:7

    Topics: Alprazolam; Amnesia; Animals; Atorvastatin; Body Weight; Cholesterol; Dietary Fats; Female; Heptanoi

2007
Possible mechanism of alprazolam-induced amnesia in mice.
    Pharmacology, 1998, Volume: 56, Issue:1

    Topics: Alprazolam; Amnesia; Animals; Azepines; Drug Evaluation, Preclinical; Female; Flumazenil; GABA Agoni

1998
Oral sedation allows for comfort and amnesia during office surgery.
    Annals of plastic surgery, 2000, Volume: 44, Issue:5

    Topics: Acetaminophen; Adult; Alprazolam; Ambulatory Surgical Procedures; Amnesia; Analgesics, Non-Narcotic;

2000
Behavioral dyscontrol associated with combined use of alprazolam and ethanol.
    The American journal of psychiatry, 1988, Volume: 145, Issue:10

    Topics: Adult; Alcohol Drinking; Alprazolam; Amnesia; Depressive Disorder; Drug Interactions; Ethanol; Femal

1988