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alprazolam and Akinetic-Rigid Variant of Huntington Disease

alprazolam has been researched along with Akinetic-Rigid Variant of Huntington Disease in 2 studies

Alprazolam: A triazolobenzodiazepine compound with antianxiety and sedative-hypnotic actions, that is efficacious in the treatment of PANIC DISORDERS, with or without AGORAPHOBIA, and in generalized ANXIETY DISORDERS. (From AMA Drug Evaluations Annual, 1994, p238)
alprazolam : A member of the class of triazolobenzodiazepines that is 4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine carrying methyl, phenyl and chloro substituents at positions 1, 6 and 8 respectively. Alprazolam is only found in individuals that have taken this drug.

Research Excerpts

ExcerptRelevanceReference
"Transgenic R6/2 mice carrying the Huntington's disease (HD) mutation show disrupted circadian rhythms that worsen as the disease progresses."1.34Pharmacological imposition of sleep slows cognitive decline and reverses dysregulation of circadian gene expression in a transgenic mouse model of Huntington's disease. ( Chesham, JE; Dyball, R; Hastings, MH; Inyushkin, AN; Maywood, ES; Morton, AJ; Pallier, PN; Zheng, Z, 2007)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pallier, PN2
Morton, AJ2
Maywood, ES1
Zheng, Z1
Chesham, JE1
Inyushkin, AN1
Dyball, R1
Hastings, MH1

Other Studies

2 other studies available for alprazolam and Akinetic-Rigid Variant of Huntington Disease

ArticleYear
Management of sleep/wake cycles improves cognitive function in a transgenic mouse model of Huntington's disease.
    Brain research, 2009, Jul-07, Volume: 1279

    Topics: Affect; Alprazolam; Animals; Benzhydryl Compounds; Body Weight; Central Nervous System Stimulants; C

2009
Pharmacological imposition of sleep slows cognitive decline and reverses dysregulation of circadian gene expression in a transgenic mouse model of Huntington's disease.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Jul-18, Volume: 27, Issue:29

    Topics: Age Factors; Alprazolam; Animals; Cell Cycle Proteins; Chloral Hydrate; Choice Behavior; Circadian R

2007