alprazolam has been researched along with Aging in 9 studies
Alprazolam: A triazolobenzodiazepine compound with antianxiety and sedative-hypnotic actions, that is efficacious in the treatment of PANIC DISORDERS, with or without AGORAPHOBIA, and in generalized ANXIETY DISORDERS. (From AMA Drug Evaluations Annual, 1994, p238)
alprazolam : A member of the class of triazolobenzodiazepines that is 4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine carrying methyl, phenyl and chloro substituents at positions 1, 6 and 8 respectively. Alprazolam is only found in individuals that have taken this drug.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Alprazolam is a benzodiazepine that, when administered acutely, results in impairments in several aspects of cognition, including attention, learning, and memory." | 2.77 | A process-based approach to characterizing the effect of acute alprazolam challenge on visual paired associate learning and memory in healthy older adults. ( Harel, BT; Lim, YY; Maruff, P; Pietrzak, RH; Scott, JC; Snyder, PJ, 2012) |
| " In each dosage group, three patients were older than and three were younger than 65 years of age." | 2.67 | Age-related digoxin-alprazolam interaction. ( Cavdar, C; Fowler, J; Guneri, S; Guven, H; Tuncok, Y, 1993) |
| "Treatment with alprazolam (1 mg/Kg) partially reversed this adverse effect of stress." | 1.30 | Effects of alprazolam on the free-choice ethanol consumption induced by isolation stress in aged rats. ( Becerra, MA; De Miguel, S; Freire-Garabal, M; Legazpi, MP; Mayán, JM; Núñez, LA; Núñez, MJ; Quintans, MR; Rey-Méndez, M; Riveiro, P; Varela, M, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (77.78) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Seifi, M | 1 |
| Swinny, JD | 1 |
| Pietrzak, RH | 1 |
| Scott, JC | 1 |
| Harel, BT | 1 |
| Lim, YY | 1 |
| Snyder, PJ | 1 |
| Maruff, P | 1 |
| Jin, L | 1 |
| Lau, CE | 1 |
| Guven, H | 1 |
| Tuncok, Y | 1 |
| Guneri, S | 1 |
| Cavdar, C | 1 |
| Fowler, J | 1 |
| Charpentier, KP | 1 |
| von Moltke, LL | 1 |
| Poku, JW | 1 |
| Harmatz, JS | 1 |
| Shader, RI | 1 |
| Greenblatt, DJ | 1 |
| Bertz, RJ | 1 |
| Kroboth, PD | 1 |
| Kroboth, FJ | 1 |
| Reynolds, IJ | 1 |
| Salek, F | 1 |
| Wright, CE | 1 |
| Smith, RB | 1 |
| Núñez, MJ | 1 |
| Riveiro, P | 1 |
| Becerra, MA | 1 |
| De Miguel, S | 1 |
| Quintans, MR | 1 |
| Núñez, LA | 1 |
| Legazpi, MP | 1 |
| Mayán, JM | 1 |
| Rey-Méndez, M | 1 |
| Varela, M | 1 |
| Freire-Garabal, M | 1 |
| Nikaido, AM | 1 |
| Ellinwood, EH | 1 |
| Heatherly, DG | 1 |
| Gupta, SK | 1 |
| Penati, G | 1 |
| Panza, G | 1 |
| Mantero, M | 1 |
| Mauri, MC | 1 |
4 trials available for alprazolam and Aging
| Article | Year |
|---|---|
A process-based approach to characterizing the effect of acute alprazolam challenge on visual paired associate learning and memory in healthy older adults.
Topics: Aged; Aged, 80 and over; Aging; Alprazolam; Anti-Anxiety Agents; Association Learning; Attention; Cr | 2012 |
Age-related digoxin-alprazolam interaction.
Topics: Aged; Aging; Alprazolam; Digoxin; Dose-Response Relationship, Drug; Drug Interactions; Humans; Middl | 1993 |
Alprazolam in young and elderly men: sensitivity and tolerance to psychomotor, sedative and memory effects.
Topics: Adult; Aged; Aging; Alprazolam; Double-Blind Method; Drug Tolerance; Humans; Male; Memory; Psychomot | 1997 |
Age-related increase in CNS sensitivity to benzodiazepines as assessed by task difficulty.
Topics: Adult; Aged; Aging; Alprazolam; Anti-Anxiety Agents; Brain; Dose-Response Relationship, Drug; Female | 1990 |
5 other studies available for alprazolam and Aging
| Article | Year |
|---|---|
Developmental and age-dependent plasticity of GABA
Topics: Aging; Alprazolam; Animals; Colon; Enteric Nervous System; GABA Modulators; Gastrointestinal Motilit | 2019 |
Determination of alprazolam and its major metabolites in serum microsamples by high-performance liquid chromatography and its application to pharmacokinetics in rats.
Topics: Acetates; Acetic Acid; Acetonitriles; Aging; Alprazolam; Animals; Buffers; Chromatography, High Pres | 1994 |
Alprazolam hydroxylation by mouse liver microsomes in vitro: the effect of age and phenobarbital induction.
Topics: Aging; Alprazolam; Animals; Anti-Anxiety Agents; Biotransformation; Cytochrome P-450 Enzyme System; | 1997 |
Effects of alprazolam on the free-choice ethanol consumption induced by isolation stress in aged rats.
Topics: Aging; Alcohol Drinking; Alcoholism; Alprazolam; Animals; Anti-Anxiety Agents; Disease Models, Anima | 1999 |
Paranoid ideation in geriatric depressed patients treated with alprazolam.
Topics: Aged; Aging; Alprazolam; Depression; Female; Humans; Male; Middle Aged; Paranoid Disorders | 1991 |