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alprazolam and Aggression

alprazolam has been researched along with Aggression in 16 studies

Alprazolam: A triazolobenzodiazepine compound with antianxiety and sedative-hypnotic actions, that is efficacious in the treatment of PANIC DISORDERS, with or without AGORAPHOBIA, and in generalized ANXIETY DISORDERS. (From AMA Drug Evaluations Annual, 1994, p238)
alprazolam : A member of the class of triazolobenzodiazepines that is 4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine carrying methyl, phenyl and chloro substituents at positions 1, 6 and 8 respectively. Alprazolam is only found in individuals that have taken this drug.

Aggression: Behavior which may be manifested by destructive and attacking action which is verbal or physical, by covert attitudes of hostility or by obstructionism.

Research Excerpts

ExcerptRelevanceReference
"23 patients with a diagnosis of panic disorder with agoraphobia were randomly assigned to 8 weeks' treatment with alprazolam or placebo."9.08Behavioural aggression in panic disorder after 8 weeks' treatment with alprazolam. ( Bond, AJ; Bruce, MS; Curran, HV; O'Sullivan, G; Shine, P, 1995)
"The activity of chronic (3 weeks) treatment with the triazolobenzodiazepines, alprazolam and adinazolam, on clonidine- and apomorphine-induced aggression were studied."7.67Effect of chronic administration of alprazolam and adinazolam on clonidine- or apomorphine-induced aggression in laboratory rodents. ( Baiguerra, G; Kostowski, W; Valzelli, L, 1986)
"Data regarding benzodiazepine and other substance use, approach and avoidance motivation, and general and physical aggressive behaviour were collected via self-report questionnaires."5.43Motivational drive and alprazolam misuse: A recipe for aggression? ( Albrecht, B; Best, D; Hall, K; Kambouropoulos, N; Staiger, PK, 2016)
"23 patients with a diagnosis of panic disorder with agoraphobia were randomly assigned to 8 weeks' treatment with alprazolam or placebo."5.08Behavioural aggression in panic disorder after 8 weeks' treatment with alprazolam. ( Bond, AJ; Bruce, MS; Curran, HV; O'Sullivan, G; Shine, P, 1995)
"Mice offspring that were exposed prenatally to alprazolam demonstrated more individual rather than group activities, avoidance of open areas, and aggression in males."3.72Effects from prenatal exposure to alprazolam on the social behavior of mice offspring. ( Christensen, HD; Gonzalez, CL; Rayburn, WF, 2003)
"The activity of chronic (3 weeks) treatment with the triazolobenzodiazepines, alprazolam and adinazolam, on clonidine- and apomorphine-induced aggression were studied."3.67Effect of chronic administration of alprazolam and adinazolam on clonidine- or apomorphine-induced aggression in laboratory rodents. ( Baiguerra, G; Kostowski, W; Valzelli, L, 1986)
"Data regarding benzodiazepine and other substance use, approach and avoidance motivation, and general and physical aggressive behaviour were collected via self-report questionnaires."1.43Motivational drive and alprazolam misuse: A recipe for aggression? ( Albrecht, B; Best, D; Hall, K; Kambouropoulos, N; Staiger, PK, 2016)
"Alprazolam exposure was associated with more aggression among C3H/He and C57BL/6 male offspring (P <."1.31Neurobehavior effects in four strains of mice offspring exposed prenatally to alprazolam. ( Christensen, HD; Gold, KM; Gonzalez, CL; Rayburn, WF, 2002)
"Alprazolam (1 mg/kg) was given orally twice daily for 8 days and once on the 9th day."1.30Aggressive and social behavior after alprazolam withdrawal: experimental therapy with Ro 19-8022. ( Krsiak, M; Miczek, KA; Podhorná, J, 1998)
"Alprazolam was more potent than diazepam and lorazepam in potentiating thiopental, ether and ethanol anesthesia in mice."1.26[Behavioral and electroencephalographic effects of alprazolam and its metabolites (author's transl)]. ( Kataoka, Y; Kawahara, K; Lee, SC; Liou, SY; Ohta, H; Shibata, K; Shibata, S; Suwandi, D; Takano, M; Tazoe, N; Ueki, S; Watanabe, S; Yamamoto, T, 1981)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19905 (31.25)18.7374
1990's4 (25.00)18.2507
2000's3 (18.75)29.6817
2010's4 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ennis, MD1
Hoffman, RL1
Ghazal, NB1
Olson, RM1
Knauer, CS1
Chio, CL1
Hyslop, DK1
Campbell, JE1
Fitzgerald, LW1
Nichols, NF1
Svensson, KA1
McCall, RB1
Haber, CL1
Kagey, ML1
Dinh, DM1
Stepita, ME2
Bain, MJ1
Wong, DM1
Alcott, CJ1
Davis, JL1
Hepworth, KL1
Wulf, L1
Coetzee, JH1
Albrecht, B1
Staiger, PK1
Hall, K1
Kambouropoulos, N1
Best, D1
Rayburn, WF2
Christensen, HD2
Gold, KM1
Gonzalez, CL2
Ueki, S1
Watanabe, S1
Yamamoto, T1
Kataoka, Y1
Tazoe, N1
Shibata, S1
Shibata, K1
Ohta, H1
Kawahara, K1
Takano, M1
Suwandi, D1
Lee, SC1
Liou, SY1
Bond, AJ2
Silveira, JC1
Curran, HV1
Bruce, MS1
O'Sullivan, G1
Shine, P1
Krsiak, M2
Podhorná, J1
Miczek, KA1
Sulcova, A1
Rudorfer, MV1
Osman, OT1
Potter, WZ1
Ortiz, A1
Gershon, S1
French, AP1
Kostowski, W1
Valzelli, L1
Baiguerra, G1

Reviews

1 review available for alprazolam and Aggression

ArticleYear
The future of neuroleptic psychopharmacology.
    The Journal of clinical psychiatry, 1986, Volume: 47 Suppl

    Topics: Acute Disease; Aggression; Alprazolam; Antipsychotic Agents; Benzodiazepines; Carbamazepine; Clinica

1986

Trials

3 trials available for alprazolam and Aggression

ArticleYear
The combination of alprazolam and alcohol on behavioral aggression.
    Journal of studies on alcohol. Supplement, 1993, Volume: 11

    Topics: Aggression; Alprazolam; Anxiety; Competitive Behavior; Ethanol; Female; Heart Rate; Humans; Male; Pl

1993
Behavioural aggression in panic disorder after 8 weeks' treatment with alprazolam.
    Journal of affective disorders, 1995, Dec-13, Volume: 35, Issue:3

    Topics: Adult; Aggression; Agoraphobia; Alprazolam; Anti-Anxiety Agents; Arousal; Competitive Behavior; Doub

1995
The future of neuroleptic psychopharmacology.
    The Journal of clinical psychiatry, 1986, Volume: 47 Suppl

    Topics: Acute Disease; Aggression; Alprazolam; Antipsychotic Agents; Benzodiazepines; Carbamazepine; Clinica

1986

Other Studies

13 other studies available for alprazolam and Aggression

ArticleYear
2,3,4,5-tetrahydro- and 2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indoles: new templates for 5-HT(2C) agonists.
    Bioorganic & medicinal chemistry letters, 2003, Jul-21, Volume: 13, Issue:14

    Topics: Aggression; Animals; Anti-Anxiety Agents; Ataxia; Azepines; Drug Design; Electroshock; Indicators an

2003
Animal behavior case of the month. Noise phobia, cognitive dysfunction, separation anxiety, attention-seeking behavior, and medical causes.
    Journal of the American Veterinary Medical Association, 2013, May-01, Volume: 242, Issue:9

    Topics: Aggression; Alprazolam; Animals; Behavior, Animal; Dog Diseases; Dogs; Dose-Response Relationship, D

2013
Animal behavior case of the month. Fear-related aggression.
    Journal of the American Veterinary Medical Association, 2014, Aug-15, Volume: 245, Issue:4

    Topics: Aggression; Alprazolam; Animals; Anti-Anxiety Agents; Anxiety Disorders; Behavior, Animal; Dogs; Fea

2014
Use of alprazolam to facilitate mare-foal bonding in an aggressive postparturient mare.
    Journal of veterinary internal medicine, 2015, Volume: 29, Issue:1

    Topics: Aggression; Alprazolam; Animals; Animals, Newborn; Animals, Suckling; Behavior, Animal; Female; GABA

2015
Motivational drive and alprazolam misuse: A recipe for aggression?
    Psychiatry research, 2016, 06-30, Volume: 240

    Topics: Adolescent; Adult; Aggression; Alprazolam; Benzodiazepines; Drive; Female; Humans; Male; Middle Aged

2016
Neurobehavior effects in four strains of mice offspring exposed prenatally to alprazolam.
    American journal of obstetrics and gynecology, 2002, Volume: 187, Issue:4

    Topics: Aggression; Alprazolam; Animals; Anti-Anxiety Agents; Anxiety, Separation; Behavior, Animal; Female;

2002
Effects from prenatal exposure to alprazolam on the social behavior of mice offspring.
    American journal of obstetrics and gynecology, 2003, Volume: 189, Issue:5

    Topics: Aggression; Alprazolam; Animals; Anti-Anxiety Agents; Behavior, Animal; Escape Reaction; Female; Mal

2003
[Behavioral and electroencephalographic effects of alprazolam and its metabolites (author's transl)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1981, Volume: 77, Issue:5

    Topics: Aggression; Alprazolam; Animals; Anticonvulsants; Behavior, Animal; Benzodiazepines; Brain; Conflict

1981
Aggressive and social behavior after alprazolam withdrawal: experimental therapy with Ro 19-8022.
    Neuroscience and biobehavioral reviews, 1998, Volume: 23, Issue:2

    Topics: Aggression; Alprazolam; Animals; Anti-Anxiety Agents; Escape Reaction; Male; Mice; Mice, Inbred ICR;

1998
Differential effects of six structurally related benzodiazepines on some ethological measures of timidity, aggression and locomotion in mice.
    Psychopharmacology, 1990, Volume: 101, Issue:3

    Topics: Aggression; Alprazolam; Animals; Anti-Anxiety Agents; Behavior, Animal; Clonazepam; Lorazepam; Male;

1990
Alprazolam and aggression.
    The American journal of psychiatry, 1989, Volume: 146, Issue:7

    Topics: Aggression; Alprazolam; Humans; Violence

1989
Dangerously aggressive behavior as a side effect of alprazolam.
    The American journal of psychiatry, 1989, Volume: 146, Issue:2

    Topics: Adult; Aggression; Alprazolam; Brain Injuries; Dangerous Behavior; Depressive Disorder; Humans; Male

1989
Effect of chronic administration of alprazolam and adinazolam on clonidine- or apomorphine-induced aggression in laboratory rodents.
    Neuropharmacology, 1986, Volume: 25, Issue:7

    Topics: Aggression; Alprazolam; Animals; Anti-Anxiety Agents; Apomorphine; Benzodiazepines; Clonidine; Desip

1986