Page last updated: 2024-10-22

alprazolam and Ache

alprazolam has been researched along with Ache in 18 studies

Alprazolam: A triazolobenzodiazepine compound with antianxiety and sedative-hypnotic actions, that is efficacious in the treatment of PANIC DISORDERS, with or without AGORAPHOBIA, and in generalized ANXIETY DISORDERS. (From AMA Drug Evaluations Annual, 1994, p238)
alprazolam : A member of the class of triazolobenzodiazepines that is 4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine carrying methyl, phenyl and chloro substituents at positions 1, 6 and 8 respectively. Alprazolam is only found in individuals that have taken this drug.

Research Excerpts

ExcerptRelevanceReference
"To evaluate five different preoperative anxiolytic regimens in cataract surgery performed under regional anesthesia; to quantify the pain associated with combined peri- and retrobulbar injection (PRBI) of local anesthetic drugs; and to describe a technique of painless eye block."9.08Evaluation of anxiolysis and pain associated with combined peri- and retrobulbar eye block for cataract surgery. ( Berry, RA; Boezaart, AP; Laubscher, JJ; Nell, ML, 1998)
"One hundred chronic pain patients were begun on alprazolam, 1."9.06Effectiveness of alprazolam in the treatment of chronic pain: results of a preliminary study. ( Cicala, RS; Westbrook, L; Wright, H, 1990)
"To evaluate the effect of pre-operative alprazolam medication on anxiety and pain in flexible cystoscopy for bladder cancer follow-up."7.85Does using alprazolam during outpatient flexible cystoscopy decrease anxiety and pain? ( Cevik, I; Dillioglugil, O; Karakose, A; Koprulu, S; Ozkan, TA, 2017)
" While undergoing treatment with the minor tranquilizer alprazolam for a coincidental psychiatric disturbance, 39 patients with malignancies and an associated causalgic pain syndrome had a marked analgesic response."7.67Analgesic effect of alprazolam in patients with chronic, organic pain of malignant origin. ( Adams, F; Fernandez, F; Holmes, VF, 1987)
"Alprazolam resulted in lower anxiety and pain ratings during pain stimulation, supporting the idea that (presumably pain-related) anxiety may increase the experience of pain."6.69No interactive effects of naltrexone and benzodiazepines on pain during phobic fear. ( Arntz, A; Janssen, SA, 1999)
"Flurbiprofen was found to have a significant analgesic effect but this was not enhanced by combining it with alprazolam."6.67Comparison of flurbiprofen and alprazolam in the management of chronic pain syndrome. ( Wilson, A, 1990)
"Alprazolam is a triazolobenzodiazepine derivative used as a tranquilizer."5.37Effects of Alprazolam, Zolpidem and Zopiclone, and of chronic inflammation on peripheral experimental algesia in Wistar rats. ( Antonescu, A; Bogdan, M; Dobjanschi, L; Moş, I; Mureşan, M; Muţiu, G; Zdrîncă, M, 2011)
" As part of an ongoing research program, we examined the effects of a commonly prescribed combination of medications for pain relief: alprazolam, a benzodiazepine, and a hydrocodone preparation, a combination opiate and acetaminophen, on a simulated driving protocol."5.27Evaluating drugged driving: Effects of exemplar pain and anxiety medications. ( Brown, TL; Gaffney, G; Milavetz, G; Spurgin, A, 2018)
"Patients experienced greater reduction in anxiety score after medication with sublingual alprazolam (mean 2."5.19Premedication with sublingual or oral alprazolam in adults undergoing diagnostic upper gastrointestinal endoscopy. ( Gholamrezaei, A; Khodadoostan, M; Minakari, M; Shavakhi, A; Shavakhi, S; Soleiman, S; Tahery, A, 2014)
"To evaluate five different preoperative anxiolytic regimens in cataract surgery performed under regional anesthesia; to quantify the pain associated with combined peri- and retrobulbar injection (PRBI) of local anesthetic drugs; and to describe a technique of painless eye block."5.08Evaluation of anxiolysis and pain associated with combined peri- and retrobulbar eye block for cataract surgery. ( Berry, RA; Boezaart, AP; Laubscher, JJ; Nell, ML, 1998)
"One hundred chronic pain patients were begun on alprazolam, 1."5.06Effectiveness of alprazolam in the treatment of chronic pain: results of a preliminary study. ( Cicala, RS; Westbrook, L; Wright, H, 1990)
"To evaluate the effect of pre-operative alprazolam medication on anxiety and pain in flexible cystoscopy for bladder cancer follow-up."3.85Does using alprazolam during outpatient flexible cystoscopy decrease anxiety and pain? ( Cevik, I; Dillioglugil, O; Karakose, A; Koprulu, S; Ozkan, TA, 2017)
" While undergoing treatment with the minor tranquilizer alprazolam for a coincidental psychiatric disturbance, 39 patients with malignancies and an associated causalgic pain syndrome had a marked analgesic response."3.67Analgesic effect of alprazolam in patients with chronic, organic pain of malignant origin. ( Adams, F; Fernandez, F; Holmes, VF, 1987)
"Alprazolam resulted in lower anxiety and pain ratings during pain stimulation, supporting the idea that (presumably pain-related) anxiety may increase the experience of pain."2.69No interactive effects of naltrexone and benzodiazepines on pain during phobic fear. ( Arntz, A; Janssen, SA, 1999)
"Flurbiprofen was found to have a significant analgesic effect but this was not enhanced by combining it with alprazolam."2.67Comparison of flurbiprofen and alprazolam in the management of chronic pain syndrome. ( Wilson, A, 1990)
"Alprazolam is a triazolobenzodiazepine derivative used as a tranquilizer."1.37Effects of Alprazolam, Zolpidem and Zopiclone, and of chronic inflammation on peripheral experimental algesia in Wistar rats. ( Antonescu, A; Bogdan, M; Dobjanschi, L; Moş, I; Mureşan, M; Muţiu, G; Zdrîncă, M, 2011)
"Alprazolam is a triazolobenzodiazepine, with a potent anxiolytic action and a short half-life."1.30Antinociceptive interaction between alprazolam and opioids. ( Pick, CG, 1997)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19902 (11.11)18.7374
1990's8 (44.44)18.2507
2000's3 (16.67)29.6817
2010's5 (27.78)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ozkan, TA1
Koprulu, S1
Karakose, A1
Dillioglugil, O1
Cevik, I1
Brown, TL1
Milavetz, G1
Gaffney, G1
Spurgin, A1
Shavakhi, A1
Soleiman, S1
Gholamrezaei, A1
Khodadoostan, M1
Shavakhi, S1
Tahery, A1
Minakari, M1
Camus, M1
Heyries, L1
Metivier-Cesbron, E1
Le Balleur, Y1
Koch, S1
Lesur, G1
Zdrîncă, M2
Muţiu, G1
Bogdan, M1
Dobjanschi, L1
Antonescu, A2
Moş, I1
Mureşan, M1
Dolezal, T1
Krsiak, M1
Loscalzo, LM1
Wasowski, C1
Paladini, AC1
Marder, M1
Silberman, EK1
Sullivan, JL1
Katz, RC1
Wilson, L1
Frazer, N1
Pick, CG1
Boezaart, AP1
Berry, RA1
Laubscher, JJ1
Nell, ML1
Hans, P1
Coussaert, E1
Cantraine, F1
Dewandre, PY1
Brichant, JF1
Grevesse, M1
Lamy, M1
Janssen, SA1
Arntz, A1
Jenck, F1
Wichmann, J1
Dautzenberg, FM1
Moreau, JL1
Ouagazzal, AM1
Martin, JR1
Lundstrom, K1
Cesura, AM1
Poli, SM1
Roever, S1
Kolczewski, S1
Adam, G1
Kilpatrick, G1
Westbrook, L1
Cicala, RS1
Wright, H1
Russell, IJ1
Fletcher, EM1
Michalek, JE1
McBroom, PC1
Hester, GG1
Wilson, A1
Fernandez, F1
Adams, F1
Holmes, VF1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison Between Sublingual and Oral Alprazolam as Conscious Sedation for Upper Gastrointestinal Endoscopy[NCT01949038]Phase 2/Phase 3220 participants (Actual)Interventional2011-09-30Completed
Comparing Efficacy of Oral Midazolam and Sublingual Alprazolam in Reducing Anxiety and Pain/Discomfort Related to Diagnostic Upper Gastrointestinal Endoscopy in Adults[NCT03130842]Phase 2/Phase 3136 participants (Actual)Interventional2016-09-17Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for alprazolam and Ache

ArticleYear
Atypical depression.
    The Psychiatric clinics of North America, 1984, Volume: 7, Issue:3

    Topics: Alprazolam; Anxiety Disorders; Benzodiazepines; Bipolar Disorder; Character; Chronic Disease; Clinic

1984

Trials

8 trials available for alprazolam and Ache

ArticleYear
Evaluating drugged driving: Effects of exemplar pain and anxiety medications.
    Traffic injury prevention, 2018, 02-28, Volume: 19, Issue:sup1

    Topics: Acetaminophen; Adult; Alprazolam; Anxiety; Cross-Over Studies; Double-Blind Method; Driving Under th

2018
Premedication with sublingual or oral alprazolam in adults undergoing diagnostic upper gastrointestinal endoscopy.
    Endoscopy, 2014, Volume: 46, Issue:8

    Topics: Administration, Intravenous; Administration, Oral; Administration, Sublingual; Adult; Alprazolam; An

2014
Premedication with sublingual or oral alprazolam in adults undergoing diagnostic upper gastrointestinal endoscopy.
    Endoscopy, 2014, Volume: 46, Issue:8

    Topics: Administration, Intravenous; Administration, Oral; Administration, Sublingual; Adult; Alprazolam; An

2014
Premedication with sublingual or oral alprazolam in adults undergoing diagnostic upper gastrointestinal endoscopy.
    Endoscopy, 2014, Volume: 46, Issue:8

    Topics: Administration, Intravenous; Administration, Oral; Administration, Sublingual; Adult; Alprazolam; An

2014
Premedication with sublingual or oral alprazolam in adults undergoing diagnostic upper gastrointestinal endoscopy.
    Endoscopy, 2014, Volume: 46, Issue:8

    Topics: Administration, Intravenous; Administration, Oral; Administration, Sublingual; Adult; Alprazolam; An

2014
Atypical depression.
    The Psychiatric clinics of North America, 1984, Volume: 7, Issue:3

    Topics: Alprazolam; Anxiety Disorders; Benzodiazepines; Bipolar Disorder; Character; Chronic Disease; Clinic

1984
Evaluation of anxiolysis and pain associated with combined peri- and retrobulbar eye block for cataract surgery.
    Journal of clinical anesthesia, 1998, Volume: 10, Issue:3

    Topics: Aged; Alprazolam; Anesthesia, Local; Anesthetics, Local; Anti-Anxiety Agents; Anxiety; Bromazepam; B

1998
No interactive effects of naltrexone and benzodiazepines on pain during phobic fear.
    Behaviour research and therapy, 1999, Volume: 37, Issue:1

    Topics: Adolescent; Adult; Alprazolam; Anxiety; Benzodiazepines; Drug Interactions; Electroshock; Female; Hu

1999
Effectiveness of alprazolam in the treatment of chronic pain: results of a preliminary study.
    The Clinical journal of pain, 1990, Volume: 6, Issue:1

    Topics: Alprazolam; Anti-Anxiety Agents; Chronic Disease; Female; Humans; Male; Pain; Pain Measurement

1990
Treatment of primary fibrositis/fibromyalgia syndrome with ibuprofen and alprazolam. A double-blind, placebo-controlled study.
    Arthritis and rheumatism, 1991, Volume: 34, Issue:5

    Topics: Adolescent; Adult; Aged; Alprazolam; Depression; Double-Blind Method; Fibromyalgia; Humans; Ibuprofe

1991
Comparison of flurbiprofen and alprazolam in the management of chronic pain syndrome.
    Psychiatric journal of the University of Ottawa : Revue de psychiatrie de l'Universite d'Ottawa, 1990, Volume: 15, Issue:3

    Topics: Adult; Aged; Alprazolam; Chronic Disease; Double-Blind Method; Female; Flurbiprofen; Humans; Male; M

1990

Other Studies

10 other studies available for alprazolam and Ache

ArticleYear
Does using alprazolam during outpatient flexible cystoscopy decrease anxiety and pain?
    Archivos espanoles de urologia, 2017, Volume: 70, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Ambulatory Care; Anti-Anxiety Agents; Anxiety; Cystoscop

2017
[Commentary on the work of Shavakhi A et al., pp. 633].
    Endoscopy, 2014, Volume: 46, Issue:8

    Topics: Alprazolam; Anxiety; Endoscopy, Gastrointestinal; Female; Humans; Hypnotics and Sedatives; Male; Pai

2014
Effects of Alprazolam, Zolpidem and Zopiclone, and of chronic inflammation on peripheral experimental algesia in Wistar rats.
    Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie, 2011, Volume: 52, Issue:1 Suppl

    Topics: Alprazolam; Animals; Azabicyclo Compounds; Chronic Disease; Granuloma, Foreign-Body; Inflammation; M

2011
Augmentation of analgesic effect of ibuprofen by alprazolam in experimental model of pain.
    Physiological research, 2002, Volume: 51, Issue:2

    Topics: Acetic Acid; Acute Disease; Administration, Oral; Alprazolam; Analgesics, Non-Narcotic; Animals; Dis

2002
Opioid receptors are involved in the sedative and antinociceptive effects of hesperidin as well as in its potentiation with benzodiazepines.
    European journal of pharmacology, 2008, Feb-12, Volume: 580, Issue:3

    Topics: Acetic Acid; Alprazolam; Analgesics; Animals; Behavior, Animal; Benzodiazepines; Dose-Response Relat

2008
Anxiety and its determinants in patients undergoing magnetic resonance imaging.
    Journal of behavior therapy and experimental psychiatry, 1994, Volume: 25, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alprazolam; Anxiety; Fear; Female; Humans; Magnetic Reso

1994
Antinociceptive interaction between alprazolam and opioids.
    Brain research bulletin, 1997, Volume: 42, Issue:3

    Topics: Alprazolam; Animals; Dose-Response Relationship, Drug; Drug Interactions; Male; Mice; Mice, Inbred S

1997
Effects of target-controlled anesthesia with propofol and sufentanil on the hemodynamic response to Mayfield head holder application.
    Acta anaesthesiologica Belgica, 1998, Volume: 49, Issue:1

    Topics: Adjuvants, Anesthesia; Alprazolam; Analysis of Variance; Anesthesia, Intravenous; Anesthetics, Intra

1998
A synthetic agonist at the orphanin FQ/nociceptin receptor ORL1: anxiolytic profile in the rat.
    Proceedings of the National Academy of Sciences of the United States of America, 2000, Apr-25, Volume: 97, Issue:9

    Topics: Acoustic Stimulation; Alprazolam; Animals; Anti-Anxiety Agents; Cognition; Conflict, Psychological;

2000
Analgesic effect of alprazolam in patients with chronic, organic pain of malignant origin.
    Journal of clinical psychopharmacology, 1987, Volume: 7, Issue:3

    Topics: Adjustment Disorders; Adolescent; Adult; Aged; Alprazolam; Causalgia; Chronic Disease; Depressive Di

1987